|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2020. CA Cancer J Clin. 70:7–30. 2020.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Ostrom QT, Gittleman H, Farah P, Ondracek
A, Chen Y, Wolinsky Y, Stroup NE, Kruchko C and Barnholtz-Sloan JS:
CBTRUS statistical report: Primary brain and central nervous system
tumors diagnosed in the United States in 2006-2010. Neuro Oncol. 15
(Suppl 2):ii1–ii56. 2013.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Louis DN, Perry A, Reifenberger G, von
Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD,
Kleihues P and Ellison DW: The 2016 world health organization
classification of tumors of the central nervous system: A summary.
Acta Neuropathol. 131:803–820. 2016.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Peciu-Florianu I, Vannod-Michel Q, Vauleon
E, Bonneterre ME and Reyns N: Long term follow-up of patients with
newly diagnosed glioblastoma treated by intraoperative photodynamic
therapy: An update from the INDYGO trial (NCT03048240). J
Neurooncol: May 16, 2024 (Epub ahead of print) doi:
10.1007/s11060-024-04693-4, 2024.
|
|
5
|
Ohgaki H and Kleihues P: The definition of
primary and secondary glioblastoma. Clin Cancer Res. 19:764–772.
2013.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Kleihues P and Ohgaki H: Primary and
secondary glioblastomas: From concept to clinical diagnosis. Neuro
Oncol. 1:44–51. 1999.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Louis DN, Perry A, Wesseling P, Brat DJ,
Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM and
Reifenberger G: , et al: The 2021 WHO classification of
tumors of the central nervous system: A summary. Neuro Oncol.
23:1231–1251. 2021.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Taphoorn MJ and Bottomley A:
Health-related quality of life and symptom research in glioblastoma
multiforme patients. Expert Rev Pharmacoecon Outcomes Res.
5:763–774. 2005.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Omuro A and DeAngelis LM: Glioblastoma and
other malignant gliomas: A clinical review. JAMA. 310:1842–1850.
2013.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Caccese M, Indraccolo S, Zagonel V and
Lombardi G: PD-1/PD-L1 immune-checkpoint inhibitors in
glioblastoma: A concise review. Crit Rev Oncol Hematol.
135:128–134. 2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Golla H, Ahmad MA, Galushko M, Hampl J,
Maarouf M, Schroeter M, Herrlinger U, Hellmich M and Voltz R:
Glioblastoma multiforme from diagnosis to death: A prospective,
hospital-based, cohort, pilot feasibility study of patient reported
symptoms and needs. Support Care Cancer. 22:3341–3352.
2014.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Patel AV, Friedenreich CM, Moore SC, Hayes
SC, Silver JK, Campbell KL, Winters-Stone K, Gerber LH, George SM,
Fulton JE, et al: American college of sports medicine roundtable
report on physical activity, sedentary behavior, and cancer
prevention and control. Med Sci Sports Exerc. 51:2391–2402.
2019.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Ashcraft KA, Warner AB, Jones LW and
Dewhirst MW: Exercise as adjunct therapy in cancer. Semin Radiat
Oncol. 29:16–24. 2019.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Yang L, Morielli AR, Heer E, Kirkham AA,
Cheung WY, Usmani N, Friedenreich CM and Courneya KS: Effects of
exercise on cancer treatment efficacy: A systematic review of
preclinical and clinical studies. Cancer Res. 81:4889–4895.
2021.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Gerritsen JK and Vincent AJ: Exercise
improves quality of life in patients with cancer: A systematic
review and meta-analysis of randomised controlled trials. Br J
Sports Med. 50:796–803. 2016.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Ohgaki H, Dessen P, Jourde B, Horstmann S,
Nishikawa T, Di Patre PL, Burkhard C, Schüler D, Probst-Hensch NM,
Maiorka PC, et al: Genetic pathways to glioblastoma: A
population-based study. Cancer Res. 64:6892–6899. 2004.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Aldape K, Zadeh G, Mansouri S,
Reifenberger G and von Deimling A: Glioblastoma: Pathology,
molecular mechanisms and markers. Acta Neuropathol. 129:829–848.
2015.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Yang L, Lin C, Wang L, Guo H and Wang X:
Hypoxia and hypoxia-inducible factors in glioblastoma multiforme
progression and therapeutic implications. Exp Cell Res.
318:2417–2426. 2012.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Lee DH, Lee TH, Jung CH and Kim YH:
Wogonin induces apoptosis by activating the AMPK and p53 signaling
pathways in human glioblastoma cells. Cell Signal. 24:2216–2225.
2012.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Nagarajan RP and Costello JF: Epigenetic
mechanisms in glioblastoma multiforme. Semin Cancer Biol.
19:188–197. 2009.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Thakkar JP, Dolecek TA, Horbinski C,
Ostrom QT, Lightner DD, Barnholtz-Sloan JS and Villano JL:
Epidemiologic and molecular prognostic review of glioblastoma.
Cancer Epidemiol Biomarkers Prev. 23:1985–1996. 2014.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Li X, Wu C, Chen N, Gu H, Yen A, Cao L,
Wang E and Wang L: PI3K/Akt/mTOR signaling pathway and targeted
therapy for glioblastoma. Oncotarget. 7:33440–33450.
2016.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Huang Y, Lin D and Taniguchi CM: Hypoxia
inducible factor (HIF) in the tumor microenvironment: Friend or
foe? Sci China Life Sci. 60:1114–1124. 2017.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Cao WD, Kawai N, Miyake K, Zhang X, Fei Z
and Tamiya T: Relationship of 14-3-3zeta (ζ), HIF-1α, and VEGF
expression in human brain gliomas. Brain Tumor Pathol. 31:1–10.
2014.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Mihaylova MM and Shaw RJ: The AMPK
signalling pathway coordinates cell growth, autophagy and
metabolism. Nat Cell Biol. 13:1016–1023. 2011.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Chhipa RR, Fan Q, Anderson J,
Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM,
Khuchua Z, et al: AMP kinase promotes glioblastoma bioenergetics
and tumour growth. Nat Cell Biol. 20:823–835. 2018.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Alfarouk KO, Verduzco D, Rauch C,
Muddathir AK, Adil HH, Elhassan GO, Ibrahim ME, Orozco JD, Cardone
RA, Reshkin SJ and Harguindey S: Glycolysis, tumor metabolism,
cancer growth and dissemination. A new pH-based etiopathogenic
perspective and therapeutic approach to an old cancer question.
Oncoscience. 1:777–802. 2014.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Morland C, Andersson KA, Haugen ØP, Hadzic
A, Kleppa L, Gille A, Rinholm JE, Palibrk V, Diget EH, Kennedy LH,
et al: Exercise induces cerebral VEGF and angiogenesis via the
lactate receptor HCAR1. Nat Commun. 8(15557)2017.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Mao P, Joshi K, Li J, Kim SH, Li P,
Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, et al:
Mesenchymal glioma stem cells are maintained by activated
glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proc
Natl Acad Sci USA. 110:8644–8649. 2013.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Codrici E, Enciu AM, Popescu ID, Mihai S
and Tanase C: Glioma stem cells and their microenvironments:
Providers of challenging therapeutic targets. Stem Cells Int.
2016(5728438)2016.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Guichet PO, Guelfi S, Teigell M, Hoppe L,
Bakalara N, Bauchet L, Duffau H, Lamszus K, Rothhut B and Hugnot
JP: Notch1 stimulation induces a vascularization switch with
pericyte-like cell differentiation of glioblastoma stem cells. Stem
Cells. 33:21–34. 2015.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Zheng H, Ying H, Yan H, Kimmelman AC,
Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, et al: p53
and Pten control neural and glioma stem/progenitor cell renewal and
differentiation. Nature. 455:1129–1133. 2008.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Zhang Y, Dube C, Gibert M Jr, Cruickshanks
N, Wang B, Coughlan M, Yang Y, Setiady I, Deveau C, Saoud K, et al:
The p53 pathway in glioblastoma. Cancers (Basel).
10(297)2018.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Brennan CW, Verhaak RGW, McKenna A, Campos
B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ,
Berman SH, et al: The somatic genomic landscape of glioblastoma.
Cell. 155:462–477. 2013.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Wakimoto H, Tanaka S, Curry WT, Loebel F,
Zhao D, Tateishi K, Chen J, Klofas LK, Lelic N, Kim JC, et al:
Targetable signaling pathway mutations are associated with
malignant phenotype in IDH-mutant gliomas. Clin Cancer Res.
20:2898–2909. 2014.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Chen CY, Chen J, He L and Stiles BL: PTEN:
Tumor suppressor and metabolic regulator. Front Endocrinol
(Lausanne). 9(338)2018.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Koul D: PTEN signaling pathways in
glioblastoma. Cancer Biol Ther. 7:1321–1325. 2008.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Han F, Hu R, Yang H, Liu J, Sui J, Xiang
X, Wang F, Chu L and Song S: PTEN gene mutations correlate to poor
prognosis in glioma patients: A meta-analysis. Onco Targets Ther.
9:3485–3492. 2016.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Pearson JRD and Regad T: Targeting
cellular pathways in glioblastoma multiforme. Signal Transduct
Target Ther. 2(17040)2017.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Galvão RP and Zong H: Inflammation and
gliomagenesis: Bi-directional communication at early and late
stages of tumor progression. Curr Pathobiol Rep. 1:19–28.
2013.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Coffelt SB, Tal AO, Scholz A, De Palma M,
Patel S, Urbich C, Biswas SK, Murdoch C, Plate KH, Reiss Y and
Lewis CE: Angiopoietin-2 regulates gene expression in
TIE2-expressing monocytes and augments their inherent proangiogenic
functions. Cancer Res. 70:5270–5280. 2010.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Gabrilovich D: Mechanisms and functional
significance of tumour-induced dendritic-cell defects. Nat Rev
Immunol. 4:941–952. 2004.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Ham SW, Jeon HY, Jin X, Kim EJ, Kim JK,
Shin YJ, Lee Y, Kim SH, Lee SY, Seo S, et al: TP53 gain-of-function
mutation promotes inflammation in glioblastoma. Cell Death Differ.
26:409–425. 2019.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Guo J, Shinriki S, Su Y, Nakamura T,
Hayashi M, Tsuda Y, Murakami Y, Tasaki M, Hide T, Takezaki T, et
al: Hypoxia suppresses cylindromatosis (CYLD) expression to promote
inflammation in glioblastoma: Possible link to acquired resistance
to anti-VEGF therapy. Oncotarget. 5:6353–6364. 2014.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Moore SC, Lee IM, Weiderpass E, Campbell
PT, Sampson JN, Kitahara CM, Keadle SK, Arem H, de Gonzalez AB,
Hartge P, et al: Association of leisure-time physical activity with
risk of 26 types of cancer in 1.44 million adults. JAMA Intern Med.
176:816–825. 2016.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Galvão DA and Newton RU: Review of
exercise intervention studies in cancer patients. J Clin Oncol.
23:899–909. 2005.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Koelwyn GJ, Quail DF, Zhang X, White RM
and Jones LW: Exercise-dependent regulation of the tumour
microenvironment. Nat Rev Cancer. 17:620–632. 2017.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Hojman P, Gehl J, Christensen JF and
Pedersen BK: Molecular mechanisms linking exercise to cancer
prevention and treatment. Cell Metab. 27:10–21. 2018.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Woods JA, Wilund KR, Martin SA and Kistler
BM: Exercise, inflammation and aging. Aging Dis. 3:130–140.
2012.PubMed/NCBI
|
|
50
|
Coffey VG and Hawley JA: The molecular
bases of training adaptation. Sports Med. 37:737–763.
2007.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Yu M, King B, Ewert E, Su X, Mardiyati N,
Zhao Z and Wang W: Exercise ACTIVATES p53 and negatively regulates
IGF-1 pathway in epidermis within a skin cancer model. PLoS One.
11(e0160939)2016.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Nezamdoost Z, Saghebjoo M, Hoshyar R,
Hedayati M and Keska A: High-intensity training and saffron:
Effects on breast cancer-related gene expression. Med Sci Sports
Exerc. 52:1470–1476. 2020.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Zaidi SK, Van Wijnen AJ, Lian JB, Stein JL
and Stein GS: Targeting deregulated epigenetic control in cancer. J
Cell Physiol. 228:2103–2108. 2013.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Ferioli M, Zauli G, Maiorano P, Milani D,
Mirandola P and Neri LM: Role of physical exercise in the
regulation of epigenetic mechanisms in inflammation, cancer,
neurodegenerative diseases, and aging process. J Cell Physiol.
234:14852–14864. 2019.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Zeng H, Irwin ML, Lu L, Risch H, Mayne S,
Mu L, Deng Q, Scarampi L, Mitidieri M, Katsaros D and Yu H:
Physical activity and breast cancer survival: An epigenetic link
through reduced methylation of a tumor suppressor gene L3MBTL1.
Breast Cancer Res Treat. 133:127–135. 2012.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Khori V, Shalamzari SA, Isanejad A,
Alizadeh AM, Alizadeh S, Khodayari S, Khodayari H, Shahbazi S,
Zahedi A, Sohanaki H, et al: Effects of exercise training together
with tamoxifen in reducing mammary tumor burden in mice: Possible
underlying pathway of miR-21. Eur J Pharmacol. 765:179–187.
2015.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Liu LZ, Li C, Chen Q, Jing Y, Carpenter R,
Jiang Y, Kung HF, Lai L and Jiang BH: MiR-21 induced angiogenesis
through AKT and ERK activation and HIF-1α expression. PLoS One.
6(e19139)2011.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Elsner VR, Lovatel GA, Bertoldi K,
Vanzella C, Santos FM, Spindler C, de Almeida EF, Nardin P and
Siqueira IR: Effect of different exercise protocols on histone
acetyltransferases and histone deacetylases activities in rat
hippocampus. Neuroscience. 192:580–587. 2011.PubMed/NCBI View Article : Google Scholar
|
|
59
|
Gomez-Pinilla F, Zhuang Y, Feng J, Ying Z
and Fan G: Exercise impacts brain-derived neurotrophic factor
plasticity by engaging mechanisms of epigenetic regulation. Eur J
Neurosci. 33:383–390. 2011.PubMed/NCBI View Article : Google Scholar
|
|
60
|
Abel JL and Rissman EF: Running-induced
epigenetic and gene expression changes in the adolescent brain. Int
J Dev Neurosci. 31:382–390. 2013.PubMed/NCBI View Article : Google Scholar
|
|
61
|
Wójtowicz K, Czarzasta K, Przepiorka L,
Kujawski S, Cudnoch-Jedrzejewska A, Marchel A and Kunert P:
Brain-Derived neurotrophic factor (BDNF) concentration levels in
cerebrospinal fluid and plasma in patients with glioblastoma: A
prospective, observational, controlled study. Cureus.
15(e48237)2023.PubMed/NCBI View Article : Google Scholar
|
|
62
|
Ng DQ, Cheng I, Wang C, Tan CJ, Toh YL,
Koh YQ, Ke Y, Foo KM, Chan RJ, Ho HK, et al: Brain-derived
neurotrophic factor as a biomarker in cancer-related cognitive
impairment among adolescent and young adult cancer patients. Sci
Rep. 13(16298)2023.PubMed/NCBI View Article : Google Scholar
|
|
63
|
Agostini D, Natalucci V, Baldelli G, De
Santi M, Zeppa SD, Vallorani L, Annibalini G, Lucertini F, Federici
A, Izzo R, et al: New insights into the role of exercise in
inhibiting mTOR signaling in triple-negative breast cancer. Oxid
Med Cell Longev. 2018(5896786)2018.PubMed/NCBI View Article : Google Scholar
|
|
64
|
Alizadeh AM, Heydari Z, Rahimi M, Bazgir
B, Shirvani H, Alipour S, Heidarian Y, Khalighfard S and Isanejad
A: Oxytocin mediates the beneficial effects of the exercise
training on breast cancer. Exp Physiol. 103:222–235.
2018.PubMed/NCBI View Article : Google Scholar
|
|
65
|
Jain RK: Antiangiogenesis strategies
revisited: From starving tumors to alleviating hypoxia. Cancer
Cell. 26:605–622. 2014.PubMed/NCBI View Article : Google Scholar
|
|
66
|
Faustino-Rocha AI, Silva A, Gabriel J, da
Costa RM, Moutinho M, Oliveira PA, Gama A, Ferreira R and Ginja M:
Long-term exercise training as a modulator of mammary cancer
vascularization. Biomed Pharmacother. 81:273–280. 2016.PubMed/NCBI View Article : Google Scholar
|
|
67
|
Isanejad A, Alizadeh AM, Shalamzari SA,
Khodayari H, Khodayari S, Khori V and Khojastehnjad N:
MicroRNA-206, let-7a and microRNA-21 pathways involved in the
anti-angiogenesis effects of the interval exercise training and
hormone therapy in breast cancer. Life Sci. 151:30–40.
2016.PubMed/NCBI View Article : Google Scholar
|
|
68
|
Jones LW, Antonelli J, Masko EM,
Broadwater G, Lascola CD, Fels D, Dewhirst MW, Dyck JR, Nagendran
J, Flores CT, et al: Exercise modulation of the host-tumor
interaction in an orthotopic model of murine prostate cancer. J
Appl Physiol (1985). 113:263–272. 2012.PubMed/NCBI View Article : Google Scholar
|
|
69
|
Jones LW, Viglianti BL, Tashjian JA,
Kothadia SM, Keir ST, Freedland SJ, Potter MQ, Moon EJ, Schroeder
T, Herndon JE II and Dewhirst MW: Effect of aerobic exercise on
tumor physiology in an animal model of human breast cancer. J Appl
Physiol. 108:343–348. 1985.PubMed/NCBI View Article : Google Scholar
|
|
70
|
Rincón-Castanedo C, Morales JS,
Martín-Ruiz A, Valenzuela PL, Ramírez M, Santos-Lozano A, Lucia A
and Fiuza-Luces C: Physical exercise effects on metastasis: A
systematic review and meta-analysis in animal cancer models. Cancer
Metastasis Rev. 39:91–114. 2020.PubMed/NCBI View Article : Google Scholar
|
|
71
|
O'Neill HM: AMPK and exercise: Glucose
uptake and insulin sensitivity. Diabetes Metab J. 37:1–21.
2013.PubMed/NCBI View Article : Google Scholar
|
|
72
|
Li W, Saud SM, Young MR, Chen G and Hua B:
Targeting AMPK for cancer prevention and treatment. Oncotarget.
6:7365–7378. 2015.PubMed/NCBI View Article : Google Scholar
|
|
73
|
Kim I and He YY: Targeting the
AMP-activated protein kinase for cancer prevention and therapy.
Front Oncol. 3(175)2013.PubMed/NCBI View Article : Google Scholar
|
|
74
|
Piguet AC, Saran U, Simillion C, Keller I,
Terracciano L, Reeves HL and Dufour JF: Regular exercise decreases
liver tumors development in hepatocyte-specific PTEN-deficient mice
independently of steatosis. J Hepatol. 62:1296–1303.
2015.PubMed/NCBI View Article : Google Scholar
|
|
75
|
Vara-Ciruelos D, Russell FM and Hardie DG:
The strange case of AMPK and cancer: Dr Jekyll or Mr
Hyde?†. Open Biol. 9(190099)2019.PubMed/NCBI View Article : Google Scholar
|
|
76
|
Hardie DG: AMPK: Positive and negative
regulation, and its role in whole-body energy homeostasis. Curr
Opin Cell Biol. 33:1–7. 2015.PubMed/NCBI View Article : Google Scholar
|
|
77
|
Faubert B, Boily G, Izreig S, Griss T,
Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, et
al: AMPK is a negative regulator of the Warburg effect and
suppresses tumor growth in vivo. Cell Metab. 17:113–124.
2013.PubMed/NCBI View Article : Google Scholar
|
|
78
|
Ponnusamy L, Natarajan SR, Thangaraj K and
Manoharan R: Therapeutic aspects of AMPK in breast cancer:
Progress, challenges, and future directions. Biochim Biophys Acta
Rev Cancer. 1874(188379)2020.PubMed/NCBI View Article : Google Scholar
|
|
79
|
Aveseh M, Nikooie R and Aminaie M:
Exercise-induced changes in tumour LDH-B and MCT1 expression are
modulated by oestrogen-related receptor alpha in breast
cancer-bearing BALB/c mice. J Physiol. 593:2635–2648.
2015.PubMed/NCBI View Article : Google Scholar
|
|
80
|
Bacurau RF, Belmonte MA, Seelaender MC and
Costa Rosa LF: Effect of a moderate intensity exercise training
protocol on the metabolism of macrophages and lymphocytes of
tumour-bearing rats. Cell Biochem Funct. 18:249–258.
2000.PubMed/NCBI View Article : Google Scholar
|
|
81
|
Campos JC, Fernandes T, Bechara LR, da
Paixão NA, Brum PC, de Oliveira EM and Ferreira JC: Increased
clearance of reactive aldehydes and damaged proteins in
hypertension-induced compensated cardiac hypertrophy: Impact of
exercise training. Oxid Med Cell Longev.
2015(464195)2015.PubMed/NCBI View Article : Google Scholar
|
|
82
|
Zhang X, Ashcraft KA, Warner AB, Nair SK
and Dewhirst MW: Can exercise-induced modulation of the tumor
physiologic microenvironment improve antitumor immunity? Cancer
Res. 79:2447–2456. 2019.PubMed/NCBI View Article : Google Scholar
|
|
83
|
Nieman DC and Wentz LM: The compelling
link between physical activity and the body's defense system. J
Sport Health Sci. 8:201–217. 2019.PubMed/NCBI View Article : Google Scholar
|
|
84
|
Campbell JP and Turner JE: Debunking the
myth of exercise-induced immune suppression: Redefining the impact
of exercise on immunological health across the lifespan. Front
Immunol. 9(648)2018.PubMed/NCBI View Article : Google Scholar
|
|
85
|
Gupta P, Bigley AB, Markofski M, Laughlin
M and LaVoy EC: Autologous serum collected 1 h post-exercise
enhances natural killer cell cytotoxicity. Brain Behav Immun.
71:81–92. 2018.PubMed/NCBI View Article : Google Scholar
|
|
86
|
Nieman DC, Henson DA, Austin MD and Brown
VA: Immune response to a 30-minute walk. Med Sci Sports Exerc.
37:57–62. 2005.PubMed/NCBI View Article : Google Scholar
|
|
87
|
Fridman WH, Pagès F, Sautès-Fridman C and
Galon J: The immune contexture in human tumours: Impact on clinical
outcome. Nat Rev Cancer. 12:298–306. 2012.PubMed/NCBI View Article : Google Scholar
|
|
88
|
Idorn M and Hojman P: Exercise-dependent
regulation of NK cells in cancer protection. Trends Mol Med.
22:565–577. 2016.PubMed/NCBI View Article : Google Scholar
|
|
89
|
Evans ES, Hackney AC, McMurray RG, Randell
SH, Muss HB, Deal AM and Battaglini CL: Impact of acute
intermittent exercise on natural killer cells in breast cancer
survivors. Integr Cancer Ther. 14:436–445. 2015.PubMed/NCBI View Article : Google Scholar
|
|
90
|
Barra NG, Fan IY, Gillen JB, Chew M,
Marcinko K, Steinberg GR, Gibala MJ and Ashkar AA: High intensity
interval training increases natural killer cell number and function
in obese breast cancer-challenged mice and obese women. J Cancer
Prev. 22:260–266. 2017.PubMed/NCBI View Article : Google Scholar
|
|
91
|
Pedersen L, Idorn M, Olofsson GH,
Lauenborg B, Nookaew I, Hansen RH, Johannesen HH, Becker JC,
Pedersen KS, Dethlefsen C, et al: Voluntary running suppresses
tumor growth through epinephrine- and IL-6-dependent NK cell
mobilization and redistribution. Cell Metab. 23:554–562.
2016.PubMed/NCBI View Article : Google Scholar
|
|
92
|
Wennerberg E, Lhuillier C, Rybstein MD,
Dannenberg K, Rudqvist NP, Koelwyn GJ, Jones LW and Demaria S:
Exercise reduces immune suppression and breast cancer progression
in a preclinical model. Oncotarget. 11:452–461. 2020.PubMed/NCBI View Article : Google Scholar
|
|
93
|
Sharma P and Allison JP: Immune checkpoint
targeting in cancer therapy: Toward combination strategies with
curative potential. Cell. 161:205–214. 2015.PubMed/NCBI View Article : Google Scholar
|
|
94
|
Schirrmacher V: From chemotherapy to
biological therapy: A review of novel concepts to reduce the side
effects of systemic cancer treatment (Review). Int J Oncol.
54:407–419. 2019.PubMed/NCBI View Article : Google Scholar
|
|
95
|
Scott JM, Khakoo A, Mackey JR, Haykowsky
MJ, Douglas PS and Jones LW: Modulation of anthracycline-induced
cardiotoxicity by aerobic exercise in breast cancer: Current
evidence and underlying mechanisms. Circulation. 124:642–650.
2011.PubMed/NCBI View Article : Google Scholar
|
|
96
|
Repka CP and Hayward R: Oxidative stress
and fitness changes in cancer patients after exercise training. Med
Sci Sports Exerc. 48:607–614. 2016.PubMed/NCBI View Article : Google Scholar
|
|
97
|
Park HS, Kim CJ, Kwak HB, No MH, Heo JW
and Kim TW: Physical exercise prevents cognitive impairment by
enhancing hippocampal neuroplasticity and mitochondrial function in
doxorubicin-induced chemobrain. Neuropharmacology. 133:451–461.
2018.PubMed/NCBI View Article : Google Scholar
|
|
98
|
Spina S, Facciorusso S, Cinone N,
Pellegrino R, Fiore P and Santamato A: Rehabilitation interventions
for glioma patients: A mini-review. Front Surg.
10(1137516)2023.PubMed/NCBI View Article : Google Scholar
|
|
99
|
Sandler CX, Matsuyama M, Jones TL,
Bashford J, Langbecker D and Hayes SC: Physical activity and
exercise in adults diagnosed with primary brain cancer: A
systematic review. J Neurooncol. 153:1–14. 2021.PubMed/NCBI View Article : Google Scholar
|
|
100
|
Pace A, Dirven L, Koekkoek JAF, Golla H,
Fleming J, Rudà R, Marosi C, Le Rhun E, Grant R, Oliver K, et al:
European association for neuro-oncology (EANO) guidelines for
palliative care in adults with glioma. Lancet Oncol. 18:e330–e340.
2017.PubMed/NCBI View Article : Google Scholar
|
|
101
|
Piil K, Juhler M, Jakobsen J and Jarden M:
Controlled rehabilitative and supportive care intervention trials
in patients with high-grade gliomas and their caregivers: A
systematic review. BMJ Support Palliat Care. 6:27–34.
2016.PubMed/NCBI View Article : Google Scholar
|
|
102
|
Vargo M: Brain tumor rehabilitation. Am J
Phys Med Rehabil. 90 (5 Suppl 1):S50–S62. 2011.PubMed/NCBI View Article : Google Scholar
|
|
103
|
Formica V, Del Monte G, Giacchetti I,
Grenga I, Giaquinto S, Fini M and Roselli M: Rehabilitation in
neuro-oncology: A meta-analysis of published data and a
mono-institutional experience. Integr Cancer Ther. 10:119–126.
2011.PubMed/NCBI View Article : Google Scholar
|
|
104
|
Roberts PS, Nuño M, Sherman D, Asher A,
Wertheimer J, Riggs RV and Patil CG: The impact of inpatient
rehabilitation on function and survival of newly diagnosed patients
with glioblastoma. PM R. 6:514–521. 2014.PubMed/NCBI View Article : Google Scholar
|
|
105
|
Capozzi LC, Boldt KR, Easaw J, Bultz B and
Culos-Reed SN: Evaluating a 12-week exercise program for brain
cancer patients. Psychooncology. 25:354–358. 2016.PubMed/NCBI View Article : Google Scholar
|
|
106
|
Riggs L, Piscione J, Laughlin S,
Cunningham T, Timmons BW, Courneya KS, Bartels U, Skocic J, de
Medeiros C, Liu F, et al: Exercise training for neural recovery in
a restricted sample of pediatric brain tumor survivors: A
controlled clinical trial with crossover of training versus no
training. Neuro Oncol. 19:440–450. 2017.PubMed/NCBI View Article : Google Scholar
|
|
107
|
Gehring K, Kloek CJ, Aaronson NK, Janssen
KW, Jones LW, Sitskoorn MM and Stuiver MM: Feasibility of a
home-based exercise intervention with remote guidance for patients
with stable grade II and III gliomas: A pilot randomized controlled
trial. Clin Rehabil. 32:352–366. 2018.PubMed/NCBI View Article : Google Scholar
|
|
108
|
Troschel FM, Brandt R, Wiewrodt R, Stummer
W and Wiewrodt D: High-intensity physical exercise in a
glioblastoma patient under multimodal treatment. Med Sci Sports
Exerc. 51:2429–2433. 2019.PubMed/NCBI View Article : Google Scholar
|
|
109
|
Halkett GKB, Cormie P, McGough S, Zopf EM,
Galvão DA, Newton RU and Nowak AK: Patients and carers'
perspectives of participating in a pilot tailored exercise program
during chemoradiotherapy for high grade glioma: A qualitative
study. Eur J Cancer Care (Engl). 30(e13453)2021.PubMed/NCBI View Article : Google Scholar
|
|
110
|
Hansen A, Søgaard K and Minet LR:
Development of an exercise intervention as part of rehabilitation
in a glioblastoma multiforme survivor during irradiation treatment:
A case report. Disabil Rehabil. 41:1608–1614. 2019.PubMed/NCBI View Article : Google Scholar
|
|
111
|
Yu J, Jung Y, Park J, Kim JM, Suh M, Cho
KG and Kim M: Intensive rehabilitation therapy following brain
tumor surgery: A pilot study of effectiveness and long-term
satisfaction. Ann Rehabil Med. 43:129–141. 2019.PubMed/NCBI View Article : Google Scholar
|
|
112
|
Hojan K and Gerreth K: Can
multidisciplinary inpatient and outpatient rehabilitation provide
sufficient prevention of disability in patients with a brain
tumor?-A case-series report of two programs and a prospective,
observational clinical trial. Int J Environ Res Public Health.
17(6488)2020.PubMed/NCBI View Article : Google Scholar
|
|
113
|
Cormie P, Nowak AK, Chambers SK, Galvão DA
and Newton RU: The potential role of exercise in neuro-oncology.
Front Oncol. 5(85)2015.PubMed/NCBI View Article : Google Scholar
|
|
114
|
Ji JF, Ji SJ, Sun R, Li K, Zhang Y, Zhang
LY and Tian Y: Forced running exercise attenuates hippocampal
neurogenesis impairment and the neurocognitive deficits induced by
whole-brain irradiation via the BDNF-mediated pathway. Biochem
Biophys Res Commun. 443:646–651. 2014.PubMed/NCBI View Article : Google Scholar
|
|
115
|
Fardell JE, Vardy J, Shah JD and Johnston
IN: Cognitive impairments caused by oxaliplatin and 5-fluorouracil
chemotherapy are ameliorated by physical activity.
Psychopharmacology (Berl). 220:183–193. 2012.PubMed/NCBI View Article : Google Scholar
|
|
116
|
Knöchel C, Oertel-Knöchel V, O'Dwyer L,
Prvulovic D, Alves G, Kollmann B and Hampel H: Cognitive and
behavioural effects of physical exercise in psychiatric patients.
Prog Neurobiol. 96:46–68. 2012.PubMed/NCBI View Article : Google Scholar
|
|
117
|
Levin GT, Greenwood KM, Singh F, Tsoi D
and Newton RU: Exercise improves physical function and mental
health of brain cancer survivors: Two exploratory case studies.
Integr Cancer Ther. 15:190–196. 2016.PubMed/NCBI View Article : Google Scholar
|
|
118
|
Gehring K, Stuiver MM, Visser E, Kloek C,
van den Bent M, Hanse M, Tijssen C, Rutten GJ, Taphoorn MJB,
Aaronson NK and Sitskoorn MM: A pilot randomized controlled trial
of exercise to improve cognitive performance in patients with
stable glioma: A proof of concept. Neuro Oncol. 22:103–115.
2020.PubMed/NCBI View Article : Google Scholar
|
|
119
|
Pieczyńska A, Zasadzka E, Pilarska A,
Procyk D, Adamska K and Hojan K: Rehabilitation exercises supported
by monitor-augmented reality for patients with high-grade glioma
undergoing radiotherapy: Results of a randomized clinical trial. J
Clin Med. 12(6838)2023.PubMed/NCBI View Article : Google Scholar
|
|
120
|
Lemke D, Pledl HW, Zorn M, Jugold M, Green
E, Blaes J, Löw S, Hertenstein A, Ott M, Sahm F, et al: Slowing
down glioblastoma progression in mice by running or the
anti-malarial drug dihydroartemisinin? Induction of oxidative
stress in murine glioblastoma therapy. Oncotarget. 7:56713–5625.
2016.PubMed/NCBI View Article : Google Scholar
|
|
121
|
Tantillo E, Colistra A, Baroncelli L,
Costa M, Caleo M and Vannini E: Voluntary physical exercise reduces
motor dysfunction and hampers tumor cell proliferation in a mouse
model of glioma. Int J Environ Res Public Health.
17(5667)2020.PubMed/NCBI View Article : Google Scholar
|
|
122
|
Betof AS, Dewhirst MW and Jones LW:
Effects and potential mechanisms of exercise training on cancer
progression: A translational perspective. Brain Behav Immun. 30
(Suppl):S75–S87. 2013.PubMed/NCBI View Article : Google Scholar
|
|
123
|
Wolff G, Davidson SJ, Wrobel JK and
Toborek M: Exercise maintains blood-brain barrier integrity during
early stages of brain metastasis formation. Biochem Biophys Res
Commun. 463:811–817. 2015.PubMed/NCBI View Article : Google Scholar
|
|
124
|
Michaelsen SR, Christensen IJ, Grunnet K,
Stockhausen MT, Broholm H, Kosteljanetz M and Poulsen HS: Clinical
variables serve as prognostic factors in a model for survival from
glioblastoma multiforme: An observational study of a cohort of
consecutive non-selected patients from a single institution. BMC
Cancer. 13(402)2013.PubMed/NCBI View Article : Google Scholar
|
|
125
|
Moore SC, Rajaraman P, Dubrow R, Darefsky
AS, Koebnick C, Hollenbeck A, Schatzkin A and Leitzmann MF: Height,
body mass index, and physical activity in relation to glioma risk.
Cancer Res. 69:8349–8355. 2009.PubMed/NCBI View Article : Google Scholar
|
|
126
|
Ruden E, Reardon DA, Coan AD, Herndon JE
II, Hornsby WE, West M, Fels DR, Desjardins A, Vredenburgh JJ,
Waner E, et al: Exercise behavior, functional capacity, and
survival in adults with malignant recurrent glioma. J Clin Oncol.
29:2918–2923. 2011.PubMed/NCBI View Article : Google Scholar
|
|
127
|
Williams PT: Reduced risk of brain cancer
mortality from walking and running. Med Sci Sports Exerc.
46:927–932. 2014.PubMed/NCBI View Article : Google Scholar
|
|
128
|
Campbell KL, Winters-Stone KM, Wiskemann
J, May AM, Schwartz AL, Courneya KS, Zucker DS, Matthews CE,
Ligibel JA, Gerber LH, et al: Exercise guidelines for cancer
survivors: Consensus statement from international multidisciplinary
roundtable. Med Sci Sports Exerc. 51:2375–2390. 2019.PubMed/NCBI View Article : Google Scholar
|
