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Review Open Access

Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review)

  • Authors:
    • Ratih Dewi Yudhani
    • Dyonisa Nasirochmi Pakha
    • Nanang Wiyono
    • Brian Wasita
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java 57126, Indonesia, Department of Anatomy, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java 57126, Indonesia, Department of Anatomical Pathology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java 57126, Indonesia
    Copyright: © Yudhani et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 70
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    Published online on: October 8, 2024
       https://doi.org/10.3892/wasj.2024.285
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Abstract

Obesity has become a global health concern, and the number of individuals with obesity continues to increase significantly worldwide. Obesity increases the risk of developing chronic diseases, resulting in increases morbidity and mortality rates in humans. Zinc (chemical symbol, Zn) has been found to be associated with obesity. Zinc participates in several physiological processes, having been shown to play roles in energy balance, lipid metabolism, appetite regulation, insulin resistance, the regulation of the serum leptin concentration, as well as in inflammatory responses. However, in terms of alleviating obesity, the molecular mechanisms underlying the role of zinc in this process remain poorly understood. Therefore, the present review aimed to provide a comprehensive analysis of what is currently known regarding the molecular mechanisms of zinc supplementation in alleviating obesity, with a focus on lipid metabolism, appetite regulation, insulin signalling and the inflammatory response. 
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Copy and paste a formatted citation
Spandidos Publications style
Yudhani RD, Pakha DN, Wiyono N and Wasita B: Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review). World Acad Sci J 6: 70, 2024.
APA
Yudhani, R.D., Pakha, D.N., Wiyono, N., & Wasita, B. (2024). Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review). World Academy of Sciences Journal, 6, 70. https://doi.org/10.3892/wasj.2024.285
MLA
Yudhani, R. D., Pakha, D. N., Wiyono, N., Wasita, B."Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review)". World Academy of Sciences Journal 6.6 (2024): 70.
Chicago
Yudhani, R. D., Pakha, D. N., Wiyono, N., Wasita, B."Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review)". World Academy of Sciences Journal 6, no. 6 (2024): 70. https://doi.org/10.3892/wasj.2024.285
Copy and paste a formatted citation
x
Spandidos Publications style
Yudhani RD, Pakha DN, Wiyono N and Wasita B: Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review). World Acad Sci J 6: 70, 2024.
APA
Yudhani, R.D., Pakha, D.N., Wiyono, N., & Wasita, B. (2024). Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review). World Academy of Sciences Journal, 6, 70. https://doi.org/10.3892/wasj.2024.285
MLA
Yudhani, R. D., Pakha, D. N., Wiyono, N., Wasita, B."Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review)". World Academy of Sciences Journal 6.6 (2024): 70.
Chicago
Yudhani, R. D., Pakha, D. N., Wiyono, N., Wasita, B."Molecular mechanisms of zinc in alleviating obesity: Recent updates (Review)". World Academy of Sciences Journal 6, no. 6 (2024): 70. https://doi.org/10.3892/wasj.2024.285
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