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Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality

  • Authors:
    • Meruyert Sharipova
    • Gulyash Tanysheva
    • Khalida Sharipova
    • Bologan Ion
    • Aizhan Shakhanova
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynaecology, Semey Medical University, Semey 071400, Republic of Kazakhstan, Department of Obstetrics and Gynaecology, Astana Medical University, Astana 010000, Republic of Kazakhstan, Department of Obstetrics and Gynaecology, Nicolae Testemițanu State University of Medicine and Pharmacy, Chisinau MD-2004, Republic of Moldova, Department of Internal Medicine and Rheumatology, Semey Medical University, Semey 071400, Republic of Kazakhstan
    Copyright: © Sharipova et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 11
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    Published online on: December 2, 2024
       https://doi.org/10.3892/wasj.2024.299
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Abstract

Females with fetuses which are considered small for gestational age (SGA) or a large for gestational age (LGA) require increased attention as regards the management of pregnancy, as they may have various pregnancy‑related complications at birth. Stillbirths are the result of fetal growth retardation (FGR) and reduced fetal reserve from stress during labor and these fetuses often do not reach their optimal birth weight. The aim of the present study was to determine the association between fetal weight and maternal physiological and pathological characteristics. The present study was a retrospective study. In the present study, 6,547 individual charts and illness lists of pregnant women hospitalized for delivery in antenatal clinics and maternity hospitals were analyzed. The results revealed that maternal physiological and pathological characteristics were statistically higher in the group of newborns with SGA and LGA than the group of newborns with a normal weight. According to the ROC analysis, maternal age, weight and body mass index (BMI) were independently associated with the risk of prediction of SGA or LGA. It was found that the maternal BMI at the beginning of pregnancy could influence the birth weight of the newborns. The maternal age and BMI were independently associated with the risk of predicting of stillbirth or perinatal mortality. On the whole, these results indicate a high risk of stillbirth and perinatal mortality regardless of fetal weight in the study population. Therefore, it is necessary to prevent the risk of stillbirth and perinatal mortality in healthy newborns, as well as in small newborns who were born with a normal weight, but have FGR.
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1 

Millogo T, Ouédraogo GH, Baguiya A, Meda IB, Kouanda S and Sondo B: Factors associated with fresh stillbirths: A hospital-based, matched, case-control study in Burkina Faso. Int J Gynecol Obstet. 135 (Suppl 1):S98–S102. 2016.PubMed/NCBI View Article : Google Scholar

2 

Bonellie S, Chalmers J, Gray R, Greer I, Jarvis S and Williams C: Centile charts for birthweight for gestational age for Scottish singleton births. BMC Pregnancy Childbirth. 8(5)2008.PubMed/NCBI View Article : Google Scholar

3 

ACOG: Fetal growth restriction. Pract Bullettin. 204:97–109. 2019.

4 

Ministry of Health of the Republic of Kazakhstan. Care of low birth weight newborns. Clin Protocol Diagnosis Treatment: 177, 2023.

5 

Ministry of Health of the Republic of Kazakhstan. Shoulder dystocia (difficulty in the shoulder girdle at birth). Clin Protocol Diagnosis Treatment: 178, 2023.

6 

Nguyen MT and Ouzounian JG: Evaluation and Management of Fetal Macrosomia. Obstet Gynecol Clin North Am. 48:387–399. 2021.PubMed/NCBI View Article : Google Scholar

7 

Beckmann CR, Ling FW, Herbert WN and Laube DWSR: Obstetrics and gynecology. Lippincott Williams & Wilkins; 8th edition. Section II. 350–366. 2019.

8 

Figueras F, Figueras J, Meler E, Eixarch E, Coll O, Gratacos E, Gardosi J and Carbonell X: Customised birthweight standards accurately predict perinatal morbidity. Arch Dis Child Fetal Neonatal Ed. 92:F277–F280. 2007.PubMed/NCBI View Article : Google Scholar

9 

Barros FC, Bhutta ZA, Batra M, Hansen TN, Victora CG and Rubens CE: GAPPS Review Group. Global report on preterm birth and stillbirth (3 of 7): Evidence for effectiveness of interventions. BMC Pregnancy Childbirth. 10 (Suppl 1)(S3)2010.PubMed/NCBI View Article : Google Scholar

10 

Risnes KR, Vatten LJ, Baker JL, Jameson K, Sovio U, Kajantie E, Osler M, Morley R, Jokela M, Painter RC, et al: Birthweight and mortality in adulthood: A systematic review and meta-analysis. Int J Epidemiol. 40:647–661. 2011.PubMed/NCBI View Article : Google Scholar

11 

Crotty M, Whitehead CH, Wundke R, Giles LC, Ben-Tovim D and Phillips PA: Transitional care facility for elderly people in hospital awaiting a long term care bed: Randomised controlled trial. Br Med J. 331:1110–1113. 2005.PubMed/NCBI View Article : Google Scholar

12 

Gardosi J, Madurasinghe V, Williams M, Malik A and Francis A: Maternal and fetal risk factors for stillbirth: Population based study. BMJ. 346(f108)2013.PubMed/NCBI View Article : Google Scholar

13 

The Investigation and Management of the Small-for-Gestational-Age Fetus. Green-top Guidel, 1-34, 2013.

14 

Williams M, Turner S, Butler E and Gardosi J: Fetal growth surveillance-Current guidelines, practices and challenges. Ultrasound. 26:69–79. 2018.PubMed/NCBI View Article : Google Scholar

15 

Ravula PC, Veluganti S, Gopireddy MMR and Aziz N: Impact of introduction of the growth assessment protocol in a South Indian tertiary hospital on SGA detection, stillbirth rate and neonatal outcome. J Perinat Med. 50:729–736. 2022.PubMed/NCBI View Article : Google Scholar

16 

Gelbaya TA and Nardo LG: Customised fetal growth chart: A systematic review. J Obstet Gynaecol. 25:445–450. 2005.PubMed/NCBI View Article : Google Scholar

17 

Gardosi J and Francis A: Controlled trial of fundal height measurement plotted on customised antenatal growth charts. Br J Obstet Gynaecol. 106:309–317. 1999.PubMed/NCBI View Article : Google Scholar

18 

Cnattingius S, Bergström R, Lipworth L and Kramer MS: Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 338:147–152. 1998.PubMed/NCBI View Article : Google Scholar

19 

Gardosi J, Clausson B and Francis A: The value of customised centiles in assessing perinatal mortality risk associated with parity and maternal size. BJOG. 116:1356–1363. 2009.PubMed/NCBI View Article : Google Scholar

20 

Gardosi J, Clausson B and Francis A: The use of customised versus population-based birthweight standards in predicting perinatal mortality. BJOG. 114:1301–1303. 2007.PubMed/NCBI View Article : Google Scholar

21 

Kiserud T, Benachi A, Hecher K, Perez RG, Carvalho J, Piaggio G and Platt LD: The World Health Organization fetal growth charts: Concept, findings, interpretation, and application. Am J Obstet Gynecol. 218 (Suppl 2):S619–S629. 2018.PubMed/NCBI View Article : Google Scholar

22 

Vayssière C, Sentilhes L, Ego A, Bernard C, Cambourieu D, Flamant C, Cambourieu D, Flamant C, Gascoin G, Gaudineau A, et al: Fetal growth restriction and intra-uterine growth restriction: Guidelines for clinical practice from the French College of Gynaecologists and Obstetricians. Eur J Obstet Gynecol Reprod Biol. 193:10–18. 2015.PubMed/NCBI View Article : Google Scholar

23 

Premru-Srsen T, Verdenik I, Mihevc Ponikvar B, Hugh O, Francis A and Gardosi J: Customised birthweight standard for a Slovenian population. J Perinat Med. 47:270–275. 2019.PubMed/NCBI View Article : Google Scholar

24 

Nasri K, Hantoushzadeh S, Hugh O, Heidarzadeh M, Habibelahi A, Shariat M, Tara F, Kashanian M, Radmehr M, Yekaninejad MS, et al: Customized birthweight standard for an Iranian population. J Matern Fetal Neonatal Med. 34:3651–3656. 2021.PubMed/NCBI View Article : Google Scholar

25 

Monier I, Blondel B, Ego A, Kaminski M, Goffinet F and Zeitlin J: Does the presence of risk factors for fetal growth restriction increase the probability of antenatal detection? A French National Study. Paediatr Perinat Epidemiol. 30:46–55. 2016.PubMed/NCBI View Article : Google Scholar

26 

Tarca AL, Romero R, Gudicha DW, Erez O, Hernandez-Andrade E, Yeo L, Bhatti G, Pacora P, Maymon E and Hassan SS: A new customized fetal growth standard for African American women: The PRB/NICHD Detroit study. Am J Obstet Gynecol. 218 (Suppl 2):S679–S691.e4. 2018.PubMed/NCBI View Article : Google Scholar

27 

Damhuis SE, Ganzevoort W and Gordijn SJ: Abnormal Fetal Growth: Small for gestational age, fetal growth restriction, large for gestational age: Definitions and epidemiology. Obstet Gynecol Clin North Am. 48:267–79. 2021.PubMed/NCBI View Article : Google Scholar

28 

Poon LCY, Volpe N, Muto B, Syngelaki A and Nicolaides KH: Birthweight with gestation and maternal characteristics in live births and stillbirths. Fetal Diagn Ther. 32:156–165. 2012.PubMed/NCBI View Article : Google Scholar

29 

Pritchard NL, Walker SP, Mitchell AR, Tong S and Lindquist AC: Adjusting growth standards for fetal sex improves correlation of small babies with stillbirth and adverse perinatal outcomes: A state-wide population study. PLoS One. 17(e0274521)2022.PubMed/NCBI View Article : Google Scholar

30 

Mifsud W and Sebire NJ: Placental pathology in early-onset and late-onset fetal growth restriction. Fetal Diagn Ther. 36:117–128. 2014.PubMed/NCBI View Article : Google Scholar

31 

Ogge G, Chaiworapongsa T, Romero R, Hussein Y, Kusanovic JP, Yeo L, Kim CJ and Hassan SS: Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia. J Perinat Med. 39:641–652. 2011.PubMed/NCBI View Article : Google Scholar

32 

Nelson DB, Ziadie MS, McIntire DD, Rogers BB and Leveno KJ: Placental pathology suggesting that preeclampsia is more than one disease. Am J Obstet Gynecol. 210:66.e1–7. 2014.PubMed/NCBI View Article : Google Scholar

33 

Liu Y, Li N, An H, Li Z, Zhang L, Li H, Zhang Y and Ye R: Impact of gestational hypertension and preeclampsia on low birthweight and small-for-gestational-age infants in China: A large prospective cohort study. J Clin Hypertens (Greenwich). 23:835–842. 2021.PubMed/NCBI View Article : Google Scholar

34 

Everett TR and Lees CC: Beyond the placental bed: Placental and systemic determinants of the uterine artery Doppler waveform. Placenta. 33:893–901. 2012.PubMed/NCBI View Article : Google Scholar

35 

Barker DJP, Bull AR, Osmond C and Simmonds SJ: Fetal and placental size and risk of hypertension in adult life. BMJ. 301:259–262. 1990.PubMed/NCBI View Article : Google Scholar

36 

Billionnet C, Mitanchez D, Weill A, Nizard J, Alla F, Hartemann A and Jacqueminet S: Gestational diabetes and adverse perinatal outcomes from 716,152 births in France in 2012. Diabetologia. 60:636–644. 2017.PubMed/NCBI View Article : Google Scholar

37 

Dittkrist L, Vetterlein J, Henrich W, Ramsauer B, Schlembach D, Abou-Dakn M, Gembruch U, Schild RL, Duewal A and Schaefer-Graf UM: Percent error of ultrasound examination to estimate fetal weight at term in different categories of birth weight with focus on maternal diabetes and obesity. BMC Pregnancy Childbirth. 22(241)2022.PubMed/NCBI View Article : Google Scholar

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Spandidos Publications style
Sharipova M, Tanysheva G, Sharipova K, Ion B and Shakhanova A: Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality. World Acad Sci J 7: 11, 2025.
APA
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., & Shakhanova, A. (2025). Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality. World Academy of Sciences Journal, 7, 11. https://doi.org/10.3892/wasj.2024.299
MLA
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., Shakhanova, A."Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality". World Academy of Sciences Journal 7.1 (2025): 11.
Chicago
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., Shakhanova, A."Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality". World Academy of Sciences Journal 7, no. 1 (2025): 11. https://doi.org/10.3892/wasj.2024.299
Copy and paste a formatted citation
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Spandidos Publications style
Sharipova M, Tanysheva G, Sharipova K, Ion B and Shakhanova A: Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality. World Acad Sci J 7: 11, 2025.
APA
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., & Shakhanova, A. (2025). Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality. World Academy of Sciences Journal, 7, 11. https://doi.org/10.3892/wasj.2024.299
MLA
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., Shakhanova, A."Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality". World Academy of Sciences Journal 7.1 (2025): 11.
Chicago
Sharipova, M., Tanysheva, G., Sharipova, K., Ion, B., Shakhanova, A."Association between maternal physiological and pathological factors and the risk of stillbirth and perinatal mortality". World Academy of Sciences Journal 7, no. 1 (2025): 11. https://doi.org/10.3892/wasj.2024.299
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