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Print ISSN: 2632-2900 Online ISSN: 2632-2919
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March-April 2026 Volume 8 Issue 2

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Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis

  • Authors:
    • Dhirajaya Dharma Kadar
    • Branson Thamran
    • Krisna Adhitya Wilantara Yusuf
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Haji Adam Malik Hospital, Medan, North Sumatra 20136, Indonesia, Department of Urology, Dr. Cipto Mangunkusumo Hospital, Jakarta 10320, Indonesia
    Copyright: © Kadar et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 22
    |
    Published online on: February 10, 2026
       https://doi.org/10.3892/wasj.2026.437
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Abstract

The present study was carried out to determine the efficacy of the apex preservation technique in the management of benign prostatic hyperplasia (BPH) complications following surgery. For this purpose, the PubMed, Embase and Cochrane Library electronic databases were widely searched for controlled trials published up to 2025. The ROBINS‑I tool was used to assess the risk of bias in the included studies. Funnel plots and Egger's regression test were applied for publication bias in the present study. GRADEpro was used to assess the quality of evidence. The results revealed that the surgery duration of the preserving technique was significantly shorter [mean difference (MD), ‑9.82; 95% confidence interval (CI), ‑13.91 to ‑5.73; P<0.00001]. The preserving technique method was associated with a lower incontinence rate (relative risk, 0.18; 95% CI, 0.07 to 0.46; P=0.0004). Blood loss in the preserving technique group was also less (MD, ‑65.37; 95% CI, ‑121.97 to ‑8.77; P=0.02). On the whole, as demonstrated herein, preserving the prostatic apex is also more time‑efficient, leading to a markedly lower risk of developing complications such as blood loss and quicker urinary continence recovery following catheter removal. This leads to improved patient satisfaction, while maintaining similar International Prostate Symptom Score, quality of life and peak urinary flow rate values. Therefore, further research is required in order to fully determine the clinical effects of prostatic apex preservation in BPH surgery in minimizing the rate of complications.

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Copy and paste a formatted citation
Spandidos Publications style
Kadar DD, Thamran B and Yusuf KA: Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis. World Acad Sci J 8: 22, 2026.
APA
Kadar, D.D., Thamran, B., & Yusuf, K.A. (2026). Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis. World Academy of Sciences Journal, 8, 22. https://doi.org/10.3892/wasj.2026.437
MLA
Kadar, D. D., Thamran, B., Yusuf, K. A."Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis". World Academy of Sciences Journal 8.2 (2026): 22.
Chicago
Kadar, D. D., Thamran, B., Yusuf, K. A."Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis". World Academy of Sciences Journal 8, no. 2 (2026): 22. https://doi.org/10.3892/wasj.2026.437
Copy and paste a formatted citation
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Spandidos Publications style
Kadar DD, Thamran B and Yusuf KA: Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis. World Acad Sci J 8: 22, 2026.
APA
Kadar, D.D., Thamran, B., & Yusuf, K.A. (2026). Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis. World Academy of Sciences Journal, 8, 22. https://doi.org/10.3892/wasj.2026.437
MLA
Kadar, D. D., Thamran, B., Yusuf, K. A."Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis". World Academy of Sciences Journal 8.2 (2026): 22.
Chicago
Kadar, D. D., Thamran, B., Yusuf, K. A."Clinical efficacy of prostatic apex preservation vs. the non‑preserving method in the management of BPH: A systematic review and meta‑analysis". World Academy of Sciences Journal 8, no. 2 (2026): 22. https://doi.org/10.3892/wasj.2026.437
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