A comprehensive review of available omics data resources and molecular profiling for precision glioma studies (Review)

  • Authors:
    • Zheng Zhao
    • Kenan Zhang
    • Zhiliang Wang
    • Kuanyu Wang
    • Xing Liu
    • Fan Wu
    • Jing Chen
  • View Affiliations

  • Published online on: November 14, 2018     https://doi.org/10.3892/br.2018.1168
  • Pages: 3-9
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Gliomas are the most common and lethal type of primary malignant central nervous system tumors, with an extremely poor prognosis. The latest progression in the technological development of sequencing/microarray and bioinformatics has provided insights into the glioma genome. These technologies have generated large amounts of easily accessible biological omics data, providing an unprecedented opportunity to study glioma formation. According to the 2016 WHO organization classification of brain tumors, gliomas are currently diagnosed with respect to morphological and molecular tumor alterations, especially for isocitrate dehydrogenase and 1p/19q codeletions. In the present study, the comprehensive molecular profiling and available omics data resources for malignant gliomas were reviewed for novel insights into the biology and classification of these tumors. These molecular profiling resources may be useful for improving the understanding of malignant gliomas, and to accelerate the clinical, experimental and epidemiological studies that may lead to improvements in the lives of patients with glioma.
View Figures
View References

Related Articles

Journal Cover

January-2019
Volume 10 Issue 1

Print ISSN: 2049-9434
Online ISSN:2049-9442

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Zhao Z, Zhang K, Wang Z, Wang K, Liu X, Wu F and Chen J: A comprehensive review of available omics data resources and molecular profiling for precision glioma studies (Review). Biomed Rep 10: 3-9, 2019
APA
Zhao, Z., Zhang, K., Wang, Z., Wang, K., Liu, X., Wu, F., & Chen, J. (2019). A comprehensive review of available omics data resources and molecular profiling for precision glioma studies (Review). Biomedical Reports, 10, 3-9. https://doi.org/10.3892/br.2018.1168
MLA
Zhao, Z., Zhang, K., Wang, Z., Wang, K., Liu, X., Wu, F., Chen, J."A comprehensive review of available omics data resources and molecular profiling for precision glioma studies (Review)". Biomedical Reports 10.1 (2019): 3-9.
Chicago
Zhao, Z., Zhang, K., Wang, Z., Wang, K., Liu, X., Wu, F., Chen, J."A comprehensive review of available omics data resources and molecular profiling for precision glioma studies (Review)". Biomedical Reports 10, no. 1 (2019): 3-9. https://doi.org/10.3892/br.2018.1168