Vitamin E slows down the progression of osteoarthritis (Review)

  • Authors:
    • Xi Li
    • Zhongli Dong
    • Fuhou Zhang
    • Junjie Dong
    • Yuan Zhang
  • View Affiliations

  • Published online on: May 10, 2016     https://doi.org/10.3892/etm.2016.3322
  • Pages: 18-22
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Abstract

Osteoarthritis is a chronic degenerative joint disorder with the characteristics of articular cartilage destruction, subchondral bone alterations and synovitis. Clinical signs and symptoms of osteoarthritis include pain, stiffness, restricted motion and crepitus. It is the major cause of joint dysfunction in developed nations and has enormous social and economic consequences. Current treatments focus on symptomatic relief, however, they lack efficacy in controlling the progression of this disease, which is a leading cause of disability. Vitamin E is safe to use and may delay the progression of osteoarthritis by acting on several aspects of the disease. In this review, how vitamin E may promote the maintenance of skeletal muscle and the regulation of nucleic acid metabolism to delay osteoarthritis progression is explored. In addition, how vitamin E may maintain the function of sex organs and the stability of mast cells, thus conferring a greater resistance to the underlying disease process is also discussed. Finally, the protective effect of vitamin E on the subchondral vascular system, which decreases the reactive remodeling in osteoarthritis, is reviewed.
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July-2016
Volume 12 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Li X, Dong Z, Zhang F, Dong J and Zhang Y: Vitamin E slows down the progression of osteoarthritis (Review). Exp Ther Med 12: 18-22, 2016
APA
Li, X., Dong, Z., Zhang, F., Dong, J., & Zhang, Y. (2016). Vitamin E slows down the progression of osteoarthritis (Review). Experimental and Therapeutic Medicine, 12, 18-22. https://doi.org/10.3892/etm.2016.3322
MLA
Li, X., Dong, Z., Zhang, F., Dong, J., Zhang, Y."Vitamin E slows down the progression of osteoarthritis (Review)". Experimental and Therapeutic Medicine 12.1 (2016): 18-22.
Chicago
Li, X., Dong, Z., Zhang, F., Dong, J., Zhang, Y."Vitamin E slows down the progression of osteoarthritis (Review)". Experimental and Therapeutic Medicine 12, no. 1 (2016): 18-22. https://doi.org/10.3892/etm.2016.3322