Open Access

Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation

  • Authors:
    • Shi-Yan Yan
    • Yi Zhang
    • Chao Sun
    • Hai-Xia Cao
    • Guang-Ming Li
    • Yu-Qin Wang
    • Jian-Gao Fan
  • View Affiliations

  • Published online on: June 10, 2016     https://doi.org/10.3892/etm.2016.3448
  • Pages: 1345-1348
  • Copyright: © Yan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary liver cancer has a high incidence and high mortality rates, and currently the only viable option is surgery, although there are a number of difficulties related to this method. The aim of the present study was to investigate the potential advantages of the real-time contrast-enhanced ultrasonography (CEUS) for microwave ablation of primary liver cancer. One hundred patients with primary liver cancer were included in the study. The patients were divided into the ordinary ultrasonography and the CEUS groups. For the ordinary ultrasonography group, the ordinary ultrasonography-guided microwave ablation method was used, while microwave ablation under the guidance of CEUS was conducted for the CEUS group. The size of lesions and clearness of the tumor boundary prior to surgery in the two groups were compared. Additionally, postoperative complications and the survival rate were monitored. Lesion boundary areas measured by CEUS were significantly larger than those measured with ordinary ultrasonography. The incidence rate of postoperative pain, fever, intra-abdominal hemorrhage and infection and other complications in the ordinary ultrasonography group were significantly higher than that in the CEUS group. The tumor recurrence rate in the CEUS group was significantly lower than that in the ordinary ultrasonography group. Seventy-two percent of patients in the CEUS group showed no progress, compared to 48% of in the ordinary ultrasonography group. The progress‑free survival rate in the CEUS group after 6 months was significantly higher than that in the ordinary ultrasonography group. Disease-free survival time in the CEUS group was considerably longer than the control group. In conclusion, the guidance of real‑time CEUS on the primary liver cancer microwave ablation treatment can achieve good intra-operative results. It offers a real-time guidance effect, improves survival time and reduces the incidence of complications.
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September-2016
Volume 12 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Yan S, Zhang Y, Sun C, Cao H, Li G, Wang Y and Fan J: Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Exp Ther Med 12: 1345-1348, 2016
APA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., & Fan, J. (2016). Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Experimental and Therapeutic Medicine, 12, 1345-1348. https://doi.org/10.3892/etm.2016.3448
MLA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12.3 (2016): 1345-1348.
Chicago
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1345-1348. https://doi.org/10.3892/etm.2016.3448