Partial response to imatinib treatment in a patient with unresectable gastrointestinal stromal tumor: A case report and mini literature review

  • Authors:
    • Xiaolong Wu
    • Libo Feng
    • Qing Liu
    • Dong Xia
    • Liang Xu
  • View Affiliations

  • Published online on: August 23, 2016     https://doi.org/10.3892/etm.2016.3614
  • Pages: 2297-2301
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Abstract

The aim of the present study was to evaluate the efficacy and safety of imatinib mesylate in unresectable gastrointestinal stromal tumor (GIST) and to discuss its therapeutic regimen. A patient with unresectable GIST is described, and several key clinical studies are reviewed, including the clinical trials B2222 and S0033, which contain recently reported results of the long‑term clinical outcome of imatinib in patients with unresectable or metastatic GIST. The recent results of the two studies demonstrate the long‑term efficacy and safety of imatinib for unresectable or metastatic GIST. A positive response to imatinib treatment was observed in the present patient, which is consistent with the data of the B2222 and S0033 trials. However, further long‑term, large‑scale, multicenter and controlled trials are required to determine the relative efficacy of combining imatinib agents with surgical procedures or administering imatinib alone.
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October-2016
Volume 12 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Wu X, Feng L, Liu Q, Xia D and Xu L: Partial response to imatinib treatment in a patient with unresectable gastrointestinal stromal tumor: A case report and mini literature review. Exp Ther Med 12: 2297-2301, 2016.
APA
Wu, X., Feng, L., Liu, Q., Xia, D., & Xu, L. (2016). Partial response to imatinib treatment in a patient with unresectable gastrointestinal stromal tumor: A case report and mini literature review. Experimental and Therapeutic Medicine, 12, 2297-2301. https://doi.org/10.3892/etm.2016.3614
MLA
Wu, X., Feng, L., Liu, Q., Xia, D., Xu, L."Partial response to imatinib treatment in a patient with unresectable gastrointestinal stromal tumor: A case report and mini literature review". Experimental and Therapeutic Medicine 12.4 (2016): 2297-2301.
Chicago
Wu, X., Feng, L., Liu, Q., Xia, D., Xu, L."Partial response to imatinib treatment in a patient with unresectable gastrointestinal stromal tumor: A case report and mini literature review". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2297-2301. https://doi.org/10.3892/etm.2016.3614