Open Access

Extramedullary hematopoiesis: A report of two cases

  • Authors:
    • Huan‑Zhu Zhang
    • Ying Li
    • Xin Liu
    • Bao‑Rong Chen
    • Guo‑Hua Yao
    • Yu‑Na Peng
  • View Affiliations

  • Published online on: November 2, 2016     https://doi.org/10.3892/etm.2016.3855
  • Pages: 3859-3862
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Extramedullary hematopoiesis (EMH) is defined as hematopoiesis occurring in organs outside of the bone marrow. The present report describes two cases of thalassemic patients with paraspinal medullary hematopoiesis and analyzes the clinical manifestations, imaging, pathology, diagnosis and treatment of EMH. In addition, a supplementary review of previously published cases is provided along with a review of the related literature. Computed tomography (CT) of the first case revealed multiple paraspinal masses, and the largest was 6.2x8.0 cm in diameter. Likewise, CT of the second patient revealed multiple paraspinal masses in the bottom of the left thoracic cavity, and the largest was measured 10.1x10.5 cm. The two cases underwent surgical biopsy and the findings were compatible with a diagnosis of EMH. In conclusion, EMH is a compatible and rare disease, and should be distinguished from other neoplasms. EMH must considered when masses with characteristic radiologic appearance are detected in patients with thalassemia intermedia.
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December-2016
Volume 12 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhang HZ, Li Y, Liu X, Chen BR, Yao GH and Peng YN: Extramedullary hematopoiesis: A report of two cases. Exp Ther Med 12: 3859-3862, 2016.
APA
Zhang, H., Li, Y., Liu, X., Chen, B., Yao, G., & Peng, Y. (2016). Extramedullary hematopoiesis: A report of two cases. Experimental and Therapeutic Medicine, 12, 3859-3862. https://doi.org/10.3892/etm.2016.3855
MLA
Zhang, H., Li, Y., Liu, X., Chen, B., Yao, G., Peng, Y."Extramedullary hematopoiesis: A report of two cases". Experimental and Therapeutic Medicine 12.6 (2016): 3859-3862.
Chicago
Zhang, H., Li, Y., Liu, X., Chen, B., Yao, G., Peng, Y."Extramedullary hematopoiesis: A report of two cases". Experimental and Therapeutic Medicine 12, no. 6 (2016): 3859-3862. https://doi.org/10.3892/etm.2016.3855