Comparison of DWIBS/T2 image fusion and PET/CT for the diagnosis of cancer in the abdominal cavity

Tomizawa,Minoru; Shinozaki,Fuminobu; Uchida,Yoshitaka; Uchiyama,Katsuhiro; Tanaka,Satomi; Sunaoshi,Takafumi; Kano,Daisuke; Sugiyama,Eriko; Shite,Misaki; Haga,Ryouta; Fukamizu,Yoshiya; Fujita,Toshiyuki; Kagayama,Satoshi; Hasegawa,Rumiko; Shirai,Yoshinori; Motoyoshi,Yasufumi; Sugiyama,Takao; Yamamoto,Shigenori; Ishige,Naoki

doi:10.3892/etm.2017.4987

Comparison of DWIBS/T2 image fusion and PET/CT for the diagnosis of cancer in the abdominal cavity

Authors:
- Minoru Tomizawa
- Fuminobu Shinozaki
- Yoshitaka Uchida
- Katsuhiro Uchiyama
- Satomi Tanaka
- Takafumi Sunaoshi
- Daisuke Kano
- Eriko Sugiyama
- Misaki Shite
- Ryouta Haga
- Yoshiya Fukamizu
- Toshiyuki Fujita
- Satoshi Kagayama
- Rumiko Hasegawa
- Yoshinori Shirai
- Yasufumi Motoyoshi
- Takao Sugiyama
- Shigenori Yamamoto
- Naoki Ishige
View Affiliations

Affiliations: Department of Gastroenterology, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Radiology, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Diagnostic PET Imaging Center, Department of Radiology, Sannoh Hospital Medical Center, Chiba 263‑0002, Japan, Department of Surgery, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurology, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Rheumatology, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Pediatrics, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurosurgery, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan
Published online on: August 22, 2017 https://doi.org/10.3892/etm.2017.4987
Pages: 3754-3760

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Fusion images of diffusion‑weighted whole‑body imaging with background body signal suppression and T2‑weighted image (DWIBS/T2) demonstrate a strong signal for malignancies, with a high contrast against the surrounding tissues, and enable anatomical analysis. In the present study, DWIBS/T2 was compared with 18F‑fluorodeoxyglucose (18F‑FDG) positron emission tomography/computed tomography (PET/CT) for diagnosing cancer in the abdomen. Patient records, including imaging results of examination conducted between November 2012 and May 2014, were analyzed retrospectively. In total, 10 men (age, 73.6±9.6 years) and 8 women (age, 68.9±7.1 years) were enrolled into the current study. Of the enrolled patients, 2 were diagnosed with hepatocellular carcinoma, 1 with cholangiocellular carcinoma, 1 with liver metastasis, 2 with pancreatic ductal adenocarcinoma, 1 with renal cell carcinoma and 1 with malignant lymphoma. Benign lesions were also analyzed, including adenomyomatosis of the gallbladder (5 patients), intraductal papillary mucinous neoplasm (4 patients) and right adrenal adenoma (1 case). All the patients with cancer showed positive results on DWIBS/T2 images. However, only 7 out of 8 patients were positive with PET/CT. One patient with right renal cellular carcinoma was positive with DWIBS/T2, but negative with PET/CT. All the patients with benign lesions were negative with DWIBS/T2 and PET/CT. In conclusion, DWIBS/T2 was more sensitive in diagnosing cancer of organs in the abdominal cavity compared with PET/CT. Furthermore, negative results with DWIBS/T2 and PET/CT were useful for the diagnosis of benign lesions, such as adenomyomatosis of the gallbladder and intraductal papillary mucinous neoplasm.