Open Access

Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm

  • Authors:
    • Xiya Chen
    • Ting Lei
  • View Affiliations

  • Published online on: May 3, 2018     https://doi.org/10.3892/etm.2018.6133
  • Pages: 236-240
  • Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study is to investigate whether glycerol fructose combined with vitamin B6 is beneficial to the postoperative recovery of patients with cerebral aneurysm (CA). A total of 134 patients receiving embolization of CA in the Central Hospital of Wuhan between February, 2013 and June, 2015 and were divided into observation and control groups according to the random number table method, with 67 cases in each group. The control was given vitamin B6 routine treatment, while the observation group received glycerol fructose on the basis of treatment in the control group. The incidence rate of postoperative complications after treatment, Glasgow coma scale (GCS) score, Barthel index score, and neurological fatigue index (NFI) score were compared between the two groups. After treatment, the GCS, Barthel index and NFI scores of patients in the observation were better than those in the control group (p<0.05), and the Barthel index score in the observation group was significantly higher than that in the control group (p<0.01). The mean flow velocity of middle cerebral artery (MCA) in the observation group after treatment was significantly different from that in the control group (p<0.05). As for complications, the incidence rates of postoperative cerebral vasospasm (1.49%), cerebral ischemia (1.49%), hematoma at puncture site (2.98%) and aneurysm rupture and hemorrhage (4.47%) in the observation group were lower than those of cerebral vasospasm (8.95%), cerebral ischemia (7.46%), hematoma at puncture site (8.95%) and aneurysm rupture and hemorrhage (10.44%) in the control group, and the differences were statistically significant (p<0.05). In conclusion, glycerol fructose combined with vitamin B6 can reduce the incidence rate of postoperative complications and improve patients' self-care ability and quality of life. Therefore, it is beneficial to postoperative recovery and it is worthy of clinical application.
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July-2018
Volume 16 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Chen X and Lei T: Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm. Exp Ther Med 16: 236-240, 2018.
APA
Chen, X., & Lei, T. (2018). Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm. Experimental and Therapeutic Medicine, 16, 236-240. https://doi.org/10.3892/etm.2018.6133
MLA
Chen, X., Lei, T."Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm". Experimental and Therapeutic Medicine 16.1 (2018): 236-240.
Chicago
Chen, X., Lei, T."Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm". Experimental and Therapeutic Medicine 16, no. 1 (2018): 236-240. https://doi.org/10.3892/etm.2018.6133