Open Access

Effects of dexmedetomidine as an adjunct in transversus abdominis plane block during gynecological laparoscopy

  • Authors:
    • Yurong Xue
    • Hui Yuan
    • Yongquan Chen
  • View Affiliations

  • Published online on: June 12, 2018     https://doi.org/10.3892/etm.2018.6295
  • Pages: 1131-1136
  • Copyright: © Xue et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Ultrasound‑guided transversus abdominis plane (TAP) block for abdominal surgery has been widely studied in clinical settings. However, dexmedetomidine as an adjunctive analgesic combined with TAP block has been rarely reported. The present study evaluated the efficacy of TAP block combined with dexmedetomidine adjunct for gynecological laparoscopy. In brief, 90 patients were randomly divided into three groups: Group I, which received post‑operative intravenous analgesia only after general anesthesia; Group II, which received a TAP block with 20 ml 0.375% ropivacaine; and Group III, which received a TAP block with 20 ml of 0.375% ropivacaine and 1 µg/kg dexmedetomidine after induction. In all groups, propofol was used for general anesthesia. The dosage of propofol, duration of the operation, and the time of awakening, spontaneous breathing and extubation were recorded. In addition, the Steward and visual analogue scale (VAS) scores were determined at 2, 4, 8, 12 and 24 h post‑surgery. The occurrence of nausea and vomiting and/or respiratory depression was also recorded. Compared with those in Group I, the dosage of propofol, as well as the time of awakening, spontaneous breathing and extubation were significantly decreased in Group III (P<0.01 and P<0.05, respectively). In addition, the VAS score at 2 and 4 h in Group II (both P<0.05) and 2, 4 (both P<0.01) and 8 h (P<0.05) in Group III after the surgery were significantly lower compared with those in Group I. Furthermore, in Groups II and III, a lower number of cases experienced nausea and vomiting (P<0.05). In conclusion, the ultrasound‑guided TAP block combined with dexmedetomidine adjunct may improve recovery from anesthesia and reduce post‑operative pain (trial registration no. ChiCTR‑IPR‑15007398).
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August-2018
Volume 16 Issue 2

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Copy and paste a formatted citation
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Spandidos Publications style
Xue Y, Yuan H and Chen Y: Effects of dexmedetomidine as an adjunct in transversus abdominis plane block during gynecological laparoscopy. Exp Ther Med 16: 1131-1136, 2018
APA
Xue, Y., Yuan, H., & Chen, Y. (2018). Effects of dexmedetomidine as an adjunct in transversus abdominis plane block during gynecological laparoscopy. Experimental and Therapeutic Medicine, 16, 1131-1136. https://doi.org/10.3892/etm.2018.6295
MLA
Xue, Y., Yuan, H., Chen, Y."Effects of dexmedetomidine as an adjunct in transversus abdominis plane block during gynecological laparoscopy". Experimental and Therapeutic Medicine 16.2 (2018): 1131-1136.
Chicago
Xue, Y., Yuan, H., Chen, Y."Effects of dexmedetomidine as an adjunct in transversus abdominis plane block during gynecological laparoscopy". Experimental and Therapeutic Medicine 16, no. 2 (2018): 1131-1136. https://doi.org/10.3892/etm.2018.6295