SNPs and haplotypes: Genetic markers for disease and drug response (Review)

  • Authors:
    • Barkur S. Shastry
  • View Affiliations

  • Published online on: March 1, 2003     https://doi.org/10.3892/ijmm.11.3.379
  • Pages: 379-382
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Abstract

The genetic make-up of an individual not only determines disease susceptibility but also response to drug treatment. It is because of this reason tremendous progress has recently been made in cataloging human sequence variations with an intention such that a high-density map will provide necessary tools to develop genetic-based diagnostic and therapeutic options. The availability of the human DNA sequence, its variation between individuals and the functional understanding of genetic determinants between individuals may enable pharmaceutical companies to discover safer and effective drugs. This will provide physicians with better tools to select the most appropriate treatment for each patient and avoid drugs that cause adverse effects. When a personalized medication becomes a more realistic and beneficial treatment, every newborn child in the neonatal unit will probably be genotyped as a routine procedure for improved treatment. This newly developed toxicogenomic or pharmacogenomic field is rapidly advancing and may change the practice of medicine in the future, providing personalized medicine for each individual.

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March 2003
Volume 11 Issue 3

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Shastry BS: SNPs and haplotypes: Genetic markers for disease and drug response (Review). Int J Mol Med 11: 379-382, 2003
APA
Shastry, B.S. (2003). SNPs and haplotypes: Genetic markers for disease and drug response (Review). International Journal of Molecular Medicine, 11, 379-382. https://doi.org/10.3892/ijmm.11.3.379
MLA
Shastry, B. S."SNPs and haplotypes: Genetic markers for disease and drug response (Review)". International Journal of Molecular Medicine 11.3 (2003): 379-382.
Chicago
Shastry, B. S."SNPs and haplotypes: Genetic markers for disease and drug response (Review)". International Journal of Molecular Medicine 11, no. 3 (2003): 379-382. https://doi.org/10.3892/ijmm.11.3.379