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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2003 Volume 11 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Influence of the intramural innervation on the morphogenesis of the enteroendocrine cells and the genetic construct involved (Review)

G. E. Holle, J. Dietl, I. Demir
Pages: 275-285
Published online on: 01 March 2003

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Article

Spatial distribution of liposome encapsulated tin etiopurpurin dichloride (SnET2) in the canine prostate: Implications for computer simulation of photodynamic therapy

Jacek Aniola, Steven H. Selman, Lothar Lilge, Rick Keck, Jerzy Jankun
Pages: 287-291
Published online on: 01 March 2003

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Article

Wilson disease protein ATP7B is localized in the late endosomes in a polarized human hepatocyte cell line

Masaru Harada, Hiroto Kumemura, Shotaro Sakisaka, Shoichiro Shishido, Eitaro Taniguchi, Takumi Kawaguchi, Shinichiro Hanada, Hironori Koga, Ryukichi Kumashiro, Takato Ueno, Tatsuo Suganuma, Koh Furuta, Masayoshi Namba, Toshihiro Sugiyama, Michio Sata
Pages: 293-298
Published online on: 01 March 2003

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Article

Role of apoptosis inhibition in various chondrocyte culture systems

Toshiaki Takahashi, Hiroshi Yamamoto, Yasuhiro Ogawa, Shoji Yoshida, Sayo Kataoka, Manas Majumdar, Elisabeth Morris, Stephen B. Tripple
Pages: 299-303
Published online on: 01 March 2003

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Article

Epidermal growth factor receptor expression in human pancreatic cancer: Significance for liver metastasis

Kosuke Tobita, Hiroshi Kijima, Shoichi Dowaki, Hiroyuki Kashiwagi, Yasuo Ohtani, Yasuhisa Oida, Hitoshi Yamazaki, Masato Nakamura, Yoshito Ueyama, Makiko Tanaka, Sadaki Inokuchi, Hiroyasu Makuuchi
Pages: 305-309
Published online on: 01 March 2003

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Article

Successive increases in human cyclin A1 promoter activity during spermatogenesis in transgenic mice

Carsten Müller-Tidow, Carol Readhead, Arthur H. Cohen, Kamlesh Asotra, Gregory Idos, Sven Diederichs, Thomas Cauvet, Rong Yang, Wolfgang E. Berdel, Hubert Serve, H. Phillip Koeffler
Pages: 311-315
Published online on: 01 March 2003

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Article

Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits

Jian-Gang Zou, Zhi-Rong Wang, Yuan-Zhu Huang, Ke-Jiang Cao, Joseph M. Wu
Pages: 317-320
Published online on: 01 March 2003

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Article

Genetic susceptibility for emphysematous changes of the lung in Japanese

Antariksa Budhi, Keiko Hiyama, Takeshi Isobe, Yoshie Oshima, Hitoshi Hara, Hiroyuki Maeda, Nobuoki Kohno
Pages: 321-329
Published online on: 01 March 2003

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Article

T cell epitopes of type II collagen in HLA-DRB1*0101 or DRB1*0405-positive Japanese patients with rheumatoid arthritis

Yasuyuki Ohnishi, Akito Tsutsumi, Tateo Sakamaki, Takayuki Sumida
Pages: 331-335
Published online on: 01 March 2003

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Article

Expression of copper-transporting P-type adenosine triphosphatase in human esophageal carcinoma

Masashi Higashimoto, Atsuko Kanzaki, Takeshi Shimakawa, Soichi Konno, Yoshihiko Naritaka, Yasutaka Nitta, Shiro Mori, Shinobu Shirata, Ayumi Yoshida, Kunihiko Terada, Toshihiro Sugiyama, Kenji Ogawa, Yuji Takebayashi
Pages: 337-341
Published online on: 01 March 2003

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Article

Telomerase activity, expression of Bcl-2 and cell cycle regulation in doxorubicin resistant gastric carcinoma cell lines

Kyong-Ah Yoon, Ja-Lok Ku, Jung Ok Yang, Jae-Gahb Park
Pages: 343-348
Published online on: 01 March 2003

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Article

Mucosal permeability regulates receptor binding of luminal epidermal growth factor in the adult rat intestine

Tomoyuki Tsujikawa, Akihiko Itoh, Takashi Yasuoka, Tetsuya Fukunaga, Jin Satoh, Katsuhiro Uda, Takashi Ihara, Masaya Sasaki, Yoshihide Fujiyama
Pages: 349-352
Published online on: 01 March 2003

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Article

Leukemia inhibitory factor regulates cell survival of normal human endometrial stromal cells

Satoko Nakajima, Tetsuji Tanaka, Naohiko Umesaki, Osamu Ishiko
Pages: 353-356
Published online on: 01 March 2003

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Article

Gender dimorphism in neutrophil priming and activation following trauma-hemorrhagic shock

Balazs Toth, Martin G. Schwacha, Joachim F. Kuebler, Kirby I. Bland, Ping Wang, Irshad H. Chaudrya
Pages: 357-364
Published online on: 01 March 2003

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Article

Percutaneous transluminal angioplasty against arteriosclerosis obliterans in dialysis patients

Kenji Tsuchida, Yoshiaki Takemoto, Kazunobu Sugimura, Rikio Yoshimura, Tatsuya Nakatani
Pages: 365-368
Published online on: 01 March 2003

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Article

Bax cleavage implicates caspase-dependent H2O2-induced apoptosis of hepatocytes

Hiroaki Tamura, Akira Ohtsuru, Yukio Kamohara, Hikaru Fujioka, Katsuhiko Yanaga, Takashi Kanematsu, Shunichi Yamashita
Pages: 369-374
Published online on: 01 March 2003

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Article

Effect of cryopreservation on in vitro clonal growth of cordonal blood cells

Laura Del Pup, Sergio De Angeli, Maria Teresa Conconi, Claudio Grandi, Pier Giorgio Gamba, Pier Paolo Parnigotto, Gastone G. Nussdorfer
Pages: 375-377
Published online on: 01 March 2003

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Review

SNPs and haplotypes: Genetic markers for disease and drug response (Review)

Barkur S. Shastry
Pages: 379-382
Published online on: 01 March 2003

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Article

Identification and characterization of human SNAIL3 (SNAI3) gene in silico

Masuko Katoh, Masaru Katoh
Pages: 383-388
Published online on: 01 March 2003

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Article

Apoptosis of bladder cancer cells induced by short-term and low-dose Mitomycin-C: Potential molecular mechanism and clinical implication

Jia Liu, Qian Wang, Xiaowei Wang, Yuan Sun, Xiao-Yan Chen, Qingyou Kong, Kai-Li Zhang, Hong Li
Pages: 389-394
Published online on: 01 March 2003

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Review

Stem cell transplantation for treatment of liver diseases: From biological foundations to clinical experience (Review)

Gennady T. Sukhikh, Alexander A. Shtil
Pages: 395-400
Published online on: 01 March 2003

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Article

The effects of interferon-γ and transforming growth factor-β on adherence and survival of group B Streptococcus type III strains in ECV304 cells

Gabriela S. Santos, Neide H.T. Miyazaki, Ana Luiza Mattos-Guaraldi, Prescilla E. Nagao
Pages: 401-406
Published online on: 01 March 2003

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
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Published online on: 30 March 2026

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Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
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Published online on: 27 March 2026

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Review Open Access

Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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