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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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December 2003 Volume 12 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December 2003 Volume 12 Issue 6

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Review

Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review)

  • Authors:
    • Toshio Inui
    • Shigeto Mizuno
    • Kenji Takai
    • Masao Nakagawa
    • Matsumi Uchida
    • Mineko Fujimiya
    • Akihiro Asakawa
    • Akio Inui
  • View Affiliations / Copyright

    Affiliations: Inui Clinic, Osaka, Japan
  • Pages: 917-921
    |
    Published online on: December 1, 2003
       https://doi.org/10.3892/ijmm.12.6.917
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Abstract

The impacts of toxins are generally observed as acute intoxications, whereas the environmental health effects of chronic exposure to mostly low levels of toxins are only poorly documented and are an emerging issue. Furthermore, toxins are potentially useful as tools to study the physiological role of particular channels or to determine structural features of channels that are important for their function. Recent studies suggest that vacuolating cytotoxin (VacA) is a novel ligand for receptor protein tyrosine phosphatase (RPTP) β. VacA is a virulence factor of Helicobacter pylori that is involved in gastric ulceration and cancer in experimental animals and humans. VacA may represent the chronic exposure of A-B family of bacterial endotoxins and be a useful probe for RPTPβ functions in the gastrointestinal system.

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Copy and paste a formatted citation
Spandidos Publications style
Inui T, Mizuno S, Takai K, Nakagawa M, Uchida M, Fujimiya M, Asakawa A and Inui A: Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review). Int J Mol Med 12: 917-921, 2003.
APA
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M. ... Inui, A. (2003). Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review). International Journal of Molecular Medicine, 12, 917-921. https://doi.org/10.3892/ijmm.12.6.917
MLA
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M., Asakawa, A., Inui, A."Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review)". International Journal of Molecular Medicine 12.6 (2003): 917-921.
Chicago
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M., Asakawa, A., Inui, A."Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review)". International Journal of Molecular Medicine 12, no. 6 (2003): 917-921. https://doi.org/10.3892/ijmm.12.6.917
Copy and paste a formatted citation
x
Spandidos Publications style
Inui T, Mizuno S, Takai K, Nakagawa M, Uchida M, Fujimiya M, Asakawa A and Inui A: Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review). Int J Mol Med 12: 917-921, 2003.
APA
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M. ... Inui, A. (2003). Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review). International Journal of Molecular Medicine, 12, 917-921. https://doi.org/10.3892/ijmm.12.6.917
MLA
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M., Asakawa, A., Inui, A."Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review)". International Journal of Molecular Medicine 12.6 (2003): 917-921.
Chicago
Inui, T., Mizuno, S., Takai, K., Nakagawa, M., Uchida, M., Fujimiya, M., Asakawa, A., Inui, A."Helicobacter pylori cytotoxin: A novel ligand for receptor-like protein tyrosine phosphatase β (Review)". International Journal of Molecular Medicine 12, no. 6 (2003): 917-921. https://doi.org/10.3892/ijmm.12.6.917
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