Tight junctions and bladder cancer (Review)

  • Authors:
    • Mark D. Haynes
    • Tracey A. Martin
    • Spencer A. Jenkins
    • Howard G. Kynaston
    • Philip N. Matthews
    • Wen G. Jiang
  • View Affiliations

  • Published online on: July 1, 2005     https://doi.org/10.3892/ijmm.16.1.3
  • Pages: 3-9
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Abstract

Tight junctions play a critical role in the maintenance of the urine-blood barrier creating a physiological barrier to the passage of ions and solutes between the urine and blood. Alterations in this urine-blood barrier function have been demonstrated in some diseases and regulation of the tight junction function has been recognised as an important aspect of the cell biology of cancer in terms of disease progression and as a potential therapeutic target. Although tight junctions play an important role in the physiological control of bladder function, there is little published on their molecular composition or regulation in the normal or diseased bladder. The purpose of this review is to summarise current understanding on the role and regulation of tight junction function in the normal and diseased bladder.

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July 2005
Volume 16 Issue 1

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Copy and paste a formatted citation
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Spandidos Publications style
Haynes MD, Martin TA, Jenkins SA, Kynaston HG, Matthews PN and Jiang WG: Tight junctions and bladder cancer (Review). Int J Mol Med 16: 3-9, 2005
APA
Haynes, M.D., Martin, T.A., Jenkins, S.A., Kynaston, H.G., Matthews, P.N., & Jiang, W.G. (2005). Tight junctions and bladder cancer (Review). International Journal of Molecular Medicine, 16, 3-9. https://doi.org/10.3892/ijmm.16.1.3
MLA
Haynes, M. D., Martin, T. A., Jenkins, S. A., Kynaston, H. G., Matthews, P. N., Jiang, W. G."Tight junctions and bladder cancer (Review)". International Journal of Molecular Medicine 16.1 (2005): 3-9.
Chicago
Haynes, M. D., Martin, T. A., Jenkins, S. A., Kynaston, H. G., Matthews, P. N., Jiang, W. G."Tight junctions and bladder cancer (Review)". International Journal of Molecular Medicine 16, no. 1 (2005): 3-9. https://doi.org/10.3892/ijmm.16.1.3