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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2005 Volume 16 Issue 1

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Tight junctions and bladder cancer (Review)

Mark D. Haynes, Tracey A. Martin, Spencer A. Jenkins, Howard G. Kynaston, Philip N. Matthews, Wen G. Jiang
Pages: 3-9
Published online on: 01 July 2005

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Article

Identification of proteins from colorectal cancer tissue by two-dimensional gel electrophoresis and SELDI mass spectrometry

Christian Melle, Dirk Osterloh, Günther Ernst, Bettina Schimmel, Annett Bleul, Ferdinand Von Eggeling
Pages: 11-17
Published online on: 01 July 2005

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Article

Cloning, expression and characterization of human glutathione S-transferase Omega 2

Liu Wang, Jian Xu, Chaoneng Ji, Shaohua Gu, You Lv, Shi Li, Yiren Xu, Yi Xie, Yumin Mao
Pages: 19-27
Published online on: 01 July 2005

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Article

Drug-induced toxic epidermal necrolysis and pancytopenia: A puzzling association

Philippe Paquet, Eric Jacob, Jean Pirson, Gerald E. Pierard
Pages: 29-33
Published online on: 01 July 2005

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Article

Differential expression and function of beacon in the rat adrenal cortex and medulla

Marcin Rucinski, Paola G. Andreis, Agnieszka Ziolkowska, Gastone G. Nussdorfer, Ludwik K. Malendowicz
Pages: 35-40
Published online on: 01 July 2005

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Article

Regulatory effects of emodin on NF-κB activation and inflammatory cytokine expression in RAW 264.7 macrophages

Hai-Long Li, Hai-Long Chen, Hong Li, Kai-Li Zhang, Xiao-Yan Chen, Xiao-Wei Wang, Qing-You Kong, Jia Liu
Pages: 41-47
Published online on: 01 July 2005

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Article

Direct effect of plasma permeability factors from patients with idiopatic FSGS on nephrin and podocin expression in human podocytes

Sophie Doublier, Luca Musante, Enrico Lupia, Giovanni Candiano, Tiziana Spatola, Gianluca Caridi, Cristina Zennaro, Michele Carraro, Gian Marco Ghiggeri, Giovanni Camussi
Pages: 49-58
Published online on: 01 July 2005

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Article

Remote delivery and expression of soluble type II TGF-β receptor in muscle prevents hepatic fibrosis in rats

Makoto Nakamuta, Shusuke Morizono, Satoru Tsuruta, Motoyuki Kohjima, Kazuhiro Kotoh, Munechika Enjoji
Pages: 59-64
Published online on: 01 July 2005

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Article

Generation and characterization of iBREC: Novel hTERT-immortalized bovine retinal endothelial cells

Heidrun Deissler, Helmut Deissler, Gerhard K. Lang, Gabriele E. Lang
Pages: 65-70
Published online on: 01 July 2005

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Article

Cytokine-induced neutrophil accumulation in the pathogenesis of acute reflux esophagitis in rats

Taiji Yamaguchi, Norimasa Yoshida, Naoya Tomatsuri, Ryuretsu Takayama, Kazuhiro Katada, Tomohisa Takagi, Hiroshi Ichikawa, Yuji Naito, Takeshi Okanoue, Toshikazu Yoshikawa
Pages: 71-77
Published online on: 01 July 2005

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Article

Frequent apoptosis in placental villi from pregnancies complicated with intrauterine growth restriction and without maternal symptoms

Hisae Endo, Aikou Okamoto, Kyosuke Yamada, Takashi Nikaido, Tadao Tanaka
Pages: 79-84
Published online on: 01 July 2005

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Article

Aberrations of the CHK2 gene are rare in pediatric solid tumors

Yu Yan Chen, Junko Takita, Kiyoshi Tanaka, Kohmei Ida, Katsuyoshi Koh, Takashi Igarashi, Ryoji Hanada, Akira Kikuchi, Yukichi Tanaka, Yasunori Toyoda, Yasuhide Hayashi
Pages: 85-91
Published online on: 01 July 2005

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Fine deletional mapping of chromosome 4q22-35 region in oral cancer

Yasuo Shinno, Esra Gunduz, Mehmet Gunduz, Hitoshi Nagatsuka, Hidetsugu Tsujigiwa, Beyhan Cengiz, You-Jin Lee, Ryo Tamamura, Mamoru Ouchida, Kunihiro Fukushima, Kenji Shimizu, Noriyuki Nagai
Pages: 93-98
Published online on: 01 July 2005

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Article

The anti-inflammatory effects of 2 Hz electroacupuncture with different intensities on acute carrageenan-induced inflammation in the rat paw

Jun-Hyuk Lee, Yung-Hyun Choi, Byung-Tae Choi
Pages: 99-102
Published online on: 01 July 2005

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Article

Roles of His9 (P2 subsite) and His13 (P3' subsite) in angiotensinogen for catalytic reaction of renin

A.H.M. Nurun Nabi, Mohammad Nasir Uddin, Tsutomu Nakagawa, Takenori Orihashi, Akio Ebihara, Atsushi Iwasawa, Yukio Nakamura, Fumiaki Suzuki
Pages: 103-107
Published online on: 01 July 2005

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Article

Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area: A pilot study

Takumi Kawaguchi, Yumiko Nagao, Kazuo Tanaka, Tatsuya Ide, Masaru Harada, Ryukichi Kumashiro, Michio Sata
Pages: 109-114
Published online on: 01 July 2005

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Article

Semaphorin 4A induces growth cone collapse of hippocampal neurons in a Rho/Rho-kinase-dependent manner

Kazunori Yukawa, Tetsuji Tanaka, Tao Bai, Takashi Ueyama, Kyoko Owada-Makabe, Yuji Tsubota, Masanobu Maeda, Kazuhiro Suzuki, Hitoshi Kikutani, Atsushi Kumanogoh
Pages: 115-118
Published online on: 01 July 2005

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Article

Evidence of dual function of macrophage migration inhibitory factor relevant to tumor progression and regression

Tsuyoshi Fukushima, Jun Nishihira, Takashi Yoshiki, Kazuya Iwabuchi, Chikako Iwabuchi, Yoshiki Yamasaki, Masao Kondo, Bailong Sun, Yuji Sato, Satoru Todo
Pages: 119-126
Published online on: 01 July 2005

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Review

Two secretory immune systems (mucosal and barrier) in human intrauterine development, normal and pathological (Review)

Itshak Zusman, Pavel Gurevich, Herzl Ben-Hur
Pages: 127-133
Published online on: 01 July 2005

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Article

CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12

Paula Maguire, Kerstin Holmberg, Maria Kost-Alimova, Stefan Imreh, Lambert Skoog, Annika Lindblom
Pages: 135-141
Published online on: 01 July 2005

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Kinetic fluorescence rt-pcr is highly sensitive for detection of germ-cell-tumor-specific transcripts in peripheral blood

M. Schrader, H. Krause, S. Weikert, B. Straub, M. Schostak, F. Christoph, K. Miller
Pages: 143-147
Published online on: 01 July 2005

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Article

The influence of lidocaine and verapamil on the proliferation, CD44 expression and apoptosis behavior of human chondrocytes

D. Wohlrab, M. Vocke, T. Klapperstück, W. Hein
Pages: 149-157
Published online on: 01 July 2005

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Article

Vascular endothelial growth factor and basic fibroblast growth factor are released by squamous cell carcinoma cells after irradiation and increase resistance to subsequent irradiation

Jürgen Brieger, Petra Schroeder, Jan Gosepath, Wolf J. Mann
Pages: 159-164
Published online on: 01 July 2005

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Article

Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection

Lewis F. Neville, Yoav Barnea, Orly Hammer-Munz, Eyal Gur, Boris Kuzmenko, Hamutal Kahel-Raifer, Rachel Eren, Adi Elkeles, Kanneganti G.K. Murthy, Csaba Szabó, Andrew L. Salzman, Shlomo Dagan, Yehuda Carmeli, Shiri Navon-Venezia
Pages: 165-171
Published online on: 01 July 2005

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Article

Combined periprocedural evaluation of CRP and TNF-α enhances the prediction of clinical restenosis and major adverse cardiac events in patients undergoing percutaneous coronary interventions

Jacek Kubica, Marek Kozinski, Anna Krzewina-Kowalska, Magdalena Zbikowska-Gotz, Grazyna Dymek, Adam Sukiennik, Radoslaw Piasecki, Maria Bogdan, Grzegorz Grzesk, Maciej Chojnicki, Andrzej Dziedziczko, Grazyna Sypniewska
Pages: 173-180
Published online on: 01 July 2005

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Article

Comparative genomics on Shisa orthologs

Yuriko Katoh, Masaru Katoh
Pages: 181-185
Published online on: 01 July 2005

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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