Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review)

  • Authors:
    • V.E. MacRae
    • S.C. Wong
    • C. Farquharson
    • S.F. Ahmed
  • View Affiliations

  • Published online on: December 1, 2006     https://doi.org/10.3892/ijmm.18.6.1011
  • Pages: 1011-1018
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Abstract

Growth disorders are commonly observed in children suffering from chronic inflammatory diseases such as Juvenile Idiopathic Arthritis (JIA) and Inflammatory Bowel Disease (IBD). These disorders range from general growth retardation to local acceleration of growth in the affected limb and are associated with the increased production of pro-inflammatory cytokines. In this article, we review how cytokines influence child growth by exerting a local effect at the level of the growth plate, and through systemic effects throughout the whole body.

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December 2006
Volume 18 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
MacRae V, Wong S, Farquharson C and Ahmed S: Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review). Int J Mol Med 18: 1011-1018, 2006.
APA
MacRae, V., Wong, S., Farquharson, C., & Ahmed, S. (2006). Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review). International Journal of Molecular Medicine, 18, 1011-1018. https://doi.org/10.3892/ijmm.18.6.1011
MLA
MacRae, V., Wong, S., Farquharson, C., Ahmed, S."Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review)". International Journal of Molecular Medicine 18.6 (2006): 1011-1018.
Chicago
MacRae, V., Wong, S., Farquharson, C., Ahmed, S."Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review)". International Journal of Molecular Medicine 18, no. 6 (2006): 1011-1018. https://doi.org/10.3892/ijmm.18.6.1011