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Connexin40 nonsense mutation in familial atrial fibrillation

  • Authors:
    • Yi-Qing Yang
    • Xian-Ling Zhang
    • Xin-Hua Wang
    • Hong-Wei Tan
    • Hai-Feng Shi
    • Wei-Feng Jiang
    • Wei-Yi Fang
    • Xu Liu

  • View Affiliations

  • Published online on: October 1, 2010     https://doi.org/10.3892/ijmm_00000505
  • Pages: 605-610
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with substantial morbidity and mortality. Genetic variants play important roles in the pathogenesis of AF. However, AF is a genetically heterogeneous disorder, and the genetic determinants in most patients with AF remain to be identified. In this study, the entire coding region of the connexin40 gene, encoding the cardiac gap junction membrane channel protein α5, was sequenced in 126 unrelated probands with familial AF. A novel heterozygous mutation, c.145C

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Journal Cover

October 2010
Volume 26 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

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  • Journal Metrics
  • Impact Factor: 5.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 10.7
  • CiteScore Rank: Q1: #35/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.994
  • SCImago Journal Rank (SJR): 0.922
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Spandidos Publications style
Yang Y, Zhang X, Wang X, Tan H, Shi H, Jiang W, Fang W and Liu X: Connexin40 nonsense mutation in familial atrial fibrillation . Int J Mol Med 26: 605-610, 2010
APA
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W. ... Liu, X. (2010). Connexin40 nonsense mutation in familial atrial fibrillation . International Journal of Molecular Medicine, 26, 605-610. https://doi.org/10.3892/ijmm_00000505
MLA
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W., Fang, W., Liu, X."Connexin40 nonsense mutation in familial atrial fibrillation ". International Journal of Molecular Medicine 26.4 (2010): 605-610.
Chicago
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W., Fang, W., Liu, X."Connexin40 nonsense mutation in familial atrial fibrillation ". International Journal of Molecular Medicine 26, no. 4 (2010): 605-610. https://doi.org/10.3892/ijmm_00000505