1
|
Fuster V, Rydén LE, Cannom DS, Crijns HJ,
Curtis AB, Ellenbogen KA, Halperin JL, Kay GN, Le Huezey JY, Lowe
JE, Olsson SB, Prystowsky EN, Tamargo JL, Wann LS, Smith SC Jr,
Priori SG, Estes NA III, Ezekowitz MD, Jackman WM, January CT, Lowe
JE, Page RL, Slotwiner DJ, Stevenson WG, Tracy CM, Jacobs AK,
Anderson JL, Albert N, Buller CE, Creager MA, Ettinger SM, Guyton
RA, Halperin JL, Hochman JS, Kushner FG, Ohman EM, Stevenson WG,
Tarkington LG and Yancy CW; American College of Cardiology
Foundation/American Heart Association Task Force. 2011 ACCF/AHA/HRS
focused updates incorporated into the ACC/AHA/ESC 2006 guidelines
for the management of patients with atrial fibrillation: a report
of the American College of Cardiology Foundation/American Heart
Association Task Force on practice guidelines. Circulation.
123:e269–e367. 2011.
|
2
|
Lloyd-Jones DM, Wang TJ, Leip EP, Larson
MG, Levy D, Vasan RS, D’Agostino RB, Massaro JM, Beiser A, Wolf PA
and Benjamin EJ: Lifetime risk for development of atrial
fibrillation: the Framingham Heart Study. Circulation.
110:1042–1046. 2004. View Article : Google Scholar : PubMed/NCBI
|
3
|
Miyasaka Y, Barnes ME, Gersh BJ, Cha SS,
Bailey KR, Abhayaratna WP, Seward JB and Tsang TS: Secular trends
in incidence of atrial fibrillation in Olmsted County, Minnesota,
1980 to 2000, and implications on the projections for future
prevalence. Circulation. 114:119–125. 2006. View Article : Google Scholar : PubMed/NCBI
|
4
|
Benjamin EJ, Wolf PA, D’Agostino RB,
Silbershatz H, Kannel WB and Levy D: Impact of atrial fibrillation
on the risk of death: the Framingham Heart Study. Circulation.
98:946–952. 1998. View Article : Google Scholar : PubMed/NCBI
|
5
|
Wolf PA, Abbott RD and Kannel WB: Atrial
fibrillation as an independent risk factor for stroke: the
Framingham Study. Stroke. 22:983–988. 1991. View Article : Google Scholar : PubMed/NCBI
|
6
|
Wolowacz SE, Samuel M, Brennan VK,
Jasso-Mosqueda JG and Van Gelder IC: The cost of illness of atrial
fibrillation: a systematic review of the recent literature.
Europace. 13:1375–1385. 2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Darbar D, Herron KJ, Ballew JD, Jahangir
A, Gersh BJ, Shen WK, Hammill SC, Packer DL and Olson TM: Familial
atrial fibrillation is a genetically heterogeneous disorder. J Am
Coll Cardiol. 41:2185–2192. 2003. View Article : Google Scholar : PubMed/NCBI
|
8
|
Ellinor PT, Yoerger DM, Ruskin JN and
MacRae CA: Familial aggregation in lone atrial fibrillation. Hum
Genet. 118:179–184. 2005. View Article : Google Scholar : PubMed/NCBI
|
9
|
Arnar DO, Thorvaldsson S, Manolio TA,
Thorgeirsson G, Kristjansson K, Hakonarson H and Stefansson K:
Familial aggregation of atrial fibrillation in Iceland. Eur Heart
J. 27:708–712. 2006. View Article : Google Scholar : PubMed/NCBI
|
10
|
Junttila MJ, Raatikainen MJ, Perkiömäki
JS, Hong K, Brugada R and Huikuri HV: Familial clustering of lone
atrial fibrillation in patients with saddleback-type ST-segment
elevation in right precordial leads. Eur Heart J. 28:463–468. 2007.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Christophersen IE, Ravn LS,
Budtz-Joergensen E, Skytthe A, Haunsoe S, Svendsen JH and
Christensen K: Familial aggregation of atrial fibrillation: a study
in Danish twins. Circ Arrhythm Electrophysiol. 2:378–383. 2009.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Yang YQ, Zhang XL, Wang XH, Tan HW, Shi
HF, Fang WY and Liu X: Familial aggregation of lone atrial
fibrillation in the Chinese population. Intern Med. 49:2385–2391.
2010. View Article : Google Scholar : PubMed/NCBI
|
13
|
Lubitz SA, Yin X, Fontes JD, Magnani JW,
Rienstra M, Pai M, Villalon ML, Vasan RS, Pencina MJ, Levy D,
Larson MG, Ellinor PT and Benjamin EJ: Association between familial
atrial fibrillation and risk of new-onset atrial fibrillation.
JAMA. 304:2263–2269. 2010. View Article : Google Scholar : PubMed/NCBI
|
14
|
Fox CS, Parise H, D’Agostino RB Sr,
Lloyd-Jones DM, Vasan RS, Wang TJ, Levy D, Wolf PA and Benjamin EJ:
Parental atrial fibrillation as a risk factor for atrial
fibrillation in offspring. JAMA. 291:2851–2855. 2004. View Article : Google Scholar : PubMed/NCBI
|
15
|
Brugada R, Tapscott T, Czernuszewicz GZ,
Marian AJ, Iglesias A, Mont L, Brugada J, Girona J, Domingo A,
Bachinski LL and Roberts R: Identification of a genetic locus for
familial atrial fibrillation. N Engl J Med. 336:905–911. 1997.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Ellinor PT, Shin JT, Moore RK, Yoerger DM
and MacRae CA: Locus for atrial fibrillation maps to chromosome
6q14-16. Circulation. 107:2880–2883. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Chen YH, Xu SJ, Bendahhou S, Wang XL, Wang
Y, Xu WY, Jin HW, Sun H, Su XY, Zhuang QN, Yang YQ, Li YB, Liu Y,
Xu HJ, Li XF, Ma N, Mou CP, Chen Z, Barhanin J and Huang W: KCNQ1
gain-of-function mutation in familial atrial fibrillation. Science.
299:251–254. 2003. View Article : Google Scholar : PubMed/NCBI
|
18
|
Oberti C, Wang L, Li L, Dong J, Rao S, Du
W and Wang Q: Genome-wide linkage scan identifies a novel genetic
locus on chromosome 5p13 for neonatal atrial fibrillation
associated with sudden death and variable cardiomyopathy.
Circulation. 110:3753–3759. 2004. View Article : Google Scholar : PubMed/NCBI
|
19
|
Zhang X, Chen S, Yoo S, Chakrabarti S,
Zhang T, Ke T, Oberti C, Yong SL, Fang F, Li L, de la Fuente R,
Wang L, Chen Q and Wang QK: Mutation in nuclear pore component
NUP155 leads to atrial fibrillation and early sudden cardiac death.
Cell. 135:1017–1027. 2008. View Article : Google Scholar : PubMed/NCBI
|
20
|
Volders PG, Zhu Q, Timmermans C, Eurlings
PM, Su X, Arens YH, Li L, Jongbloed RJ, Xia M, Rodriguez LM and
Chen YH: Mapping a novel locus for familial atrial fibrillation on
chromosome 10p11-q21. Heart Rhythm. 4:469–475. 2007. View Article : Google Scholar : PubMed/NCBI
|
21
|
Darbar D, Hardy A, Haines JL and Roden DM:
Prolonged signal-averaged P-wave duration as an intermediate
phenotype for familial atrial fibrillation. J Am Coll Cardiol.
51:1083–1089. 2008. View Article : Google Scholar : PubMed/NCBI
|
22
|
Yang Y, Xia M, Jin Q, Bendahhou S, Shi J
and Chen Y, Liang B, Lin J, Liu Y, Liu B, Zhou Q, Zhang D, Wang R,
Ma N, Su X, Niu K, Pei Y, Xu W, Chen Z, Wan H, Cui J, Barhanin J
and Chen Y: Identification of a KCNE2 gain-of-function mutation in
patients with familial atrial fibrillation. Am J Hum Genet.
75:899–905. 2004. View
Article : Google Scholar : PubMed/NCBI
|
23
|
Hong K, Bjerregaard P, Gussak I and
Brugada R: Short QT syndrome and atrial fibrillation caused by
mutation in KCNH2. J Cardiovasc Electrophysiol. 16:394–396. 2005.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Xia M, Jin Q, Bendahhou S, He Y, Larroque
MM and Chen Y, Zhou Q, Yang Y, Liu Y, Liu B, Zhu Q, Zhou Y, Lin J,
Liang B, Li L, Dong X, Pan Z, Wang R, Wan H, Qiu W, Xu W, Eurlings
P, Barhanin J and Chen Y: A Kir2.1 gain-of-function mutation
underlies familial atrial fibrillation. Biochem Biophys Res Commun.
332:1012–1019. 2005. View Article : Google Scholar : PubMed/NCBI
|
25
|
Olson TM, Alekseev AE, Liu XK, Park S,
Zingman LV, Bienengraeber M, Sattiraju S, Ballew JD, Jahangir A and
Terzic A: Kv1.5 channelopathy due to KCNA5 loss-of-function
mutation causes human atrial fibrillation. Hum Mol Genet.
15:2185–2191. 2006. View Article : Google Scholar : PubMed/NCBI
|
26
|
Olson TM, Michels VV, Ballew JD, Reyna SP,
Karst ML, Herron KJ, Horton SC, Rodeheffer RJ and Anderson JL:
Sodium channel mutations and susceptibility to heart failure and
atrial fibrillation. JAMA. 293:447–454. 2005. View Article : Google Scholar
|
27
|
Li RG, Wang Q, Xu YJ, Zhang M, Qu XK, Liu
X, Fang WY and Yang YQ: Mutations of SCN4B-encoded sodium
channel β4 subunit in familial atrial fibrillation. Int J Mol Med.
32:144–150. 2013.
|
28
|
Hodgson-Zingman DM, Karst ML, Zingman LV,
Heublein DM, Darbar D, Herron KJ, Ballew JD, de Andrade M, Burnett
JC Jr and Olson TM: Atrial natriuretic peptide frameshift mutation
in familial atrial fibrillation. N Engl J Med. 359:158–165. 2008.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Gollob MH, Jones DL, Krahn AD, Danis L,
Gong XQ, Shao Q, Liu X, Veinot JP, Tang AS, Stewart AF, Tesson F,
Klein GJ, Yee R, Skanes AC, Guiraudon GM, Ebihara L and Bai D:
Somatic mutations in the connexin 40 gene (GJA5) in atrial
fibrillation. N Engl J Med. 354:2677–2688. 2006. View Article : Google Scholar : PubMed/NCBI
|
30
|
Yang YQ, Zhang XL, Wang XH, Tan HW, Shi
HF, Jiang WF, Fang WY and Liu X: Connexin40 nonsense mutation in
familial atrial fibrillation. Int J Mol Med. 26:605–610.
2010.PubMed/NCBI
|
31
|
Sun Y, Yang YQ, Gong XQ, Wang XH, Li RG,
Tan HW, Liu X, Fang WY and Bai D: Novel germline GJA5/connexin40
mutations associated with lone atrial fibrillation impair gap
junctional intercellular communication. Hum Mutat. 34:603–609.
2013.PubMed/NCBI
|
32
|
Shi HF, Yang JF, Wang Q, Li RG, Xu YJ, Qu
XK, Fang WY, Liu X and Yang YQ: Prevalence and spectrum of GJA5
mutations associated with lone atrial fibrillation. Mol Med Rep.
7:767–774. 2013.PubMed/NCBI
|
33
|
Yang YQ, Wang MY, Zhang XL, Tan HW, Shi
HF, Jiang WF, Wang XH, Fang WY and Liu X: GATA4 loss-of-function
mutations in familial atrial fibrillation. Clin Chim Acta.
412:1825–1830. 2011. View Article : Google Scholar : PubMed/NCBI
|
34
|
Jiang JQ, Shen FF, Fang WY, Liu X and Yang
YQ: Novel GATA4 mutations in lone atrial fibrillation. Int J Mol
Med. 28:1025–1032. 2011.PubMed/NCBI
|
35
|
Wang J, Sun YM and Yang YQ: utation
spectrum of the GATA4 gene in patients with idiopathic atrial
fibrillation. Mol Biol Rep. 39:8127–8135. 2012. View Article : Google Scholar : PubMed/NCBI
|
36
|
Yang YQ, Wang J, Wang XH, Wang Q, Tan HW,
Zhang M, Shen FF, Jiang JQ, Fang WY and Liu X: Mutational spectrum
of the GATA5 gene associated with familial atrial fibrillation. Int
J Cardiol. 157:305–307. 2012. View Article : Google Scholar : PubMed/NCBI
|
37
|
Wang XH, Huang CX, Wang Q, Li RG, Xu YJ,
Liu X, Fang WY and Yang YQ: A novel GATA5 loss-of-function mutation
underlies lone atrial fibrillation. Int J Mol Med. 31:43–50.
2013.PubMed/NCBI
|
38
|
Gu JY, Xu JH, Yu H and Yang YQ: Novel
GATA5 loss-of-function mutations underlie familial atrial
fibrillation. Clinics (Sao Paulo). 67:1393–1399. 2012. View Article : Google Scholar : PubMed/NCBI
|
39
|
Yang YQ, Wang XH, Tan HW, Jiang WF, Fang
WY and Liu X: Prevalence and spectrum of GATA6 mutations associated
with familial atrial fibrillation. Int J Cardiol. 155:494–496.
2012. View Article : Google Scholar : PubMed/NCBI
|
40
|
Yang YQ, Li L, Wang J, Zhang XL, Li RG, Xu
YJ, Tan HW, Wang XH, Jiang JQ, Fang WY and Liu X: GATA6
loss-of-function mutation in atrial fibrillation. Eur J Med Genet.
55:520–526. 2012. View Article : Google Scholar : PubMed/NCBI
|
41
|
Li J, Liu WD, Yang ZL and Yang YQ: Novel
GATA6 loss-of-function mutation responsible for familial atrial
fibrillation. Int J Mol Med. 30:783–790. 2012.PubMed/NCBI
|
42
|
Huang RT, Xue S, Xu YJ, Zhou M and Yang
YQ: A novel NKX2.5 loss-of-function mutation responsible for
familial atrial fibrillation. Int J Mol Med. 31:1119–1126.
2013.PubMed/NCBI
|
43
|
Gudbjartsson DF, Arnar DO, Helgadottir A,
Gretarsdottir S, Holm H, Sigurdsson A, Jonasdottir A, Baker A,
Thorleifsson G, Kristjansson K, Palsson A, Blondal T, Sulem P,
Backman VM, Hardarson GA, Palsdottir E, Helgason A, Sigurjonsdottir
R, Sverrisson JT, Kostulas K, Ng MC, Baum L, So WY, Wong KS, Chan
JC, Furie KL, Greenberg SM, Sale M, Kelly P, MacRae CA, Smith EE,
Rosand J, Hillert J, Ma RC, Ellinor PT, Thorgeirsson G, Gulcher JR,
Kong A, Thorsteinsdottir U and Stefansson K: Variants conferring
risk of atrial fibrillation on chromosome 4q25. Nature.
448:353–357. 2007. View Article : Google Scholar : PubMed/NCBI
|
44
|
Kääb S, Darbar D, van Noord C, Dupuis J,
Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF,
Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J,
Perz S, Lunetta KL, Larson MG, Levy D, MacRae CA, Ruskin JN, Wacker
A, Schömig A, Wichmann HE, Steinbeck G, Meitinger T, Uitterlinden
AG, Witteman JC, Roden DM, Benjamin EJ and Ellinor PT: Large scale
replication and meta-analysis of variants on chromosome 4q25
associated with atrial fibrillation. Eur Heart J. 30:813–819.
2009.PubMed/NCBI
|
45
|
Body SC, Collard CD, Shernan SK, Fox AA,
Liu KY, Ritchie MD, Perry TE, Muehlschlegel JD, Aranki S, Donahue
BS, Pretorius M, Estrada JC, Ellinor PT, Newton-Cheh C, Seidman CE,
Seidman JG, Herman DS, Lichtner P, Meitinger T, Pfeufer A, Kääb S,
Brown NJ, Roden DM and Darbar D: Variation in the 4q25 chromosomal
locus predicts atrial fibrillation after coronary artery bypass
graft surgery. Circ Cardiovasc Genet. 2:499–506. 2009. View Article : Google Scholar : PubMed/NCBI
|
46
|
Husser D, Adams V, Piorkowski C, Hindricks
G and Bollmann A: Chromosome 4q25 variants and atrial fibrillation
recurrence after catheter ablation. J Am Coll Cardiol. 55:747–753.
2010. View Article : Google Scholar : PubMed/NCBI
|
47
|
Ritchie MD, Rowan S, Kucera G,
Stubblefield T, Blair M, Carter S, Roden DM and Darbar D:
Chromosome 4q25 variants are genetic modifiers of rare ion channel
mutations associated with familial atrial fibrillation. J Am Coll
Cardiol. 60:1173–1181. 2012. View Article : Google Scholar : PubMed/NCBI
|
48
|
Clauss S and Kääb S: Is Pitx2 growing up?
Circ Cardiovasc Genet. 4:105–107. 2011. View Article : Google Scholar : PubMed/NCBI
|
49
|
Haïssaguerre M, Jaïs P, Shah DC, Takahashi
A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Métayer P and
Clémenty J: Spontaneous initiation of atrial fibrillation by
ectopic beats originating in the pulmonary veins. N Engl J Med.
339:659–666. 1998.PubMed/NCBI
|
50
|
Douglas YL, Jongbloed MR, Deruiter MC and
Gittenberger-de Groot AC: Normal and abnormal development of
pulmonary veins: state of the art and correlation with clinical
entities. Int J Cardiol. 147:13–24. 2011. View Article : Google Scholar : PubMed/NCBI
|
51
|
Wang J, Klysik E, Sood S, Johnson RL,
Wehrens XH and Martin JF: Pitx2 prevents susceptibility to atrial
arrhythmias by inhibiting left-sided pacemaker specification. Proc
Natl Acad Sci USA. 107:9753–9758. 2010. View Article : Google Scholar : PubMed/NCBI
|
52
|
Chinchilla A, Daimi H, Lozano-Velasco E,
Dominguez JN, Caballero R, Delpón E, Tamargo J, Cinca J,
Hove-Madsen L, Aranega AE and Franco D: PITX2 insufficiency leads
to atrial electrical and structural remodeling linked to
arrhythmogenesis. Circ Cardiovasc Genet. 4:269–279. 2011.
View Article : Google Scholar : PubMed/NCBI
|
53
|
Kirchhof P, Kahr PC, Kaese S, Piccini I,
Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S,
Verheule S, Schotten U, Fabritz L and Brown NA: PITX2c is expressed
in the adult left atrium, and reducing Pitx2c expression promotes
atrial fibrillation inducibility and complex changes in gene
expression. Circ Cardiovasc Genet. 4:123–133. 2011. View Article : Google Scholar : PubMed/NCBI
|
54
|
Strungaru MH, Footz T, Liu Y, Berry FB,
Belleau P, Semina EV, Raymond V and Walter MA: PITX2 is involved in
stress response in cultured human trabecular meshwork cells through
regulation of SLC13A3. Invest Ophthalmol Vis Sci. 52:7625–7633.
2011. View Article : Google Scholar : PubMed/NCBI
|
55
|
Footz T, Idrees F, Acharya M, Kozlowski K
and Walter MA: Analysis of mutations of the PITX2 transcription
factor found in patients with Axenfeld-Rieger syndrome. Invest
Ophthalmol Vis Sci. 50:2599–2606. 2009. View Article : Google Scholar : PubMed/NCBI
|
56
|
Acharya M, Lingenfelter DJ, Huang L, Gage
PJ and Walter MA: Human PRKC apoptosis WT1 regulator is a novel
PITX2-interacting protein that regulates PITX2 transcriptional
activity in ocular cells. J Biol Chem. 284:34829–34838. 2009.
View Article : Google Scholar : PubMed/NCBI
|
57
|
Simard A, Di Giorgio L, Amen M, Westwood
A, Amendt BA and Ryan AK: The Pitx2c N-terminal domain is a
critical interaction domain required for asymmetric morphogenesis.
Dev Dyn. 238:2459–2470. 2009. View Article : Google Scholar : PubMed/NCBI
|
58
|
Semina EV, Reiter R, Leysens NJ, Alward
WL, Small KW, Datson NA, Siegel-Bartelt J, Bierke-Nelson D, Bitoun
P, Zabel BU, Carey JC and Murray JC: Cloning and characterization
of a novel bicoid-related homeobox transcription factor gene, RIEG,
involved in Rieger syndrome. Nat Genet. 14:392–399. 1996.
View Article : Google Scholar : PubMed/NCBI
|
59
|
Ganga M, Espinoza HM, Cox CJ, Morton L,
Hjalt TA, Lee Y and Amendt BA: PITX2 isoform-specific regulation of
atrial natriuretic factor expression: synergism and repression with
Nkx2.5. J Biol Chem. 278:22437–22445. 2003. View Article : Google Scholar : PubMed/NCBI
|
60
|
Mommersteeg MT, Brown NA, Prall OW, de
Gier-de Vries C, Harvey RP, Moorman AF and Christoffels VM: Pitx2c
and Nkx2-5 are required for the formation and identity of the
pulmonary myocardium. Circ Res. 101:902–909. 2007. View Article : Google Scholar : PubMed/NCBI
|
61
|
Mommersteeg MT, Christoffels VM, Anderson
RH and Moorman AF: Atrial fibrillation: a developmental point of
view. Heart Rhythm. 6:1818–1824. 2009. View Article : Google Scholar : PubMed/NCBI
|
62
|
Thibodeau IL, Xu J, Li Q, Liu G, Lam K,
Veinot JP, Birnie DH, Jones DL, Krahn AD, Lemery R, Nicholson BJ
and Gollob MH: Paradigm of genetic mosaicism and lone atrial
fibrillation: physiological characterization of a connexin
43-deletion mutant identified from atrial tissue. Circulation.
122:236–244. 2010. View Article : Google Scholar
|