1
|
Boersma E, Mercado N, Poldermans D,
Gardien M, Vos J and Simoons ML: Acute myocardial infarction.
361:847–858. 2003.
|
2
|
Uccelli A, Moretta L and Pistoia V:
Mesenchymal stem cells in health and disease. Nat Rev Immunol.
8:726–736. 2008. View
Article : Google Scholar
|
3
|
Gnecchi M, He H, Liang OD, Melo LG,
Morello F, Mu H, Noiseux N, Zhang L, Pratt RE, Ingwall JS and Dzau
VJ: Paracrine action accounts for marked protection of ischemic
heart by Akt-modified mesenchymal stem cells. Nat Med. 11:367–368.
2005. View Article : Google Scholar : PubMed/NCBI
|
4
|
Dai W, Hale SL, Martin BJ, Kuang JQ, Dow
JS, Wold LE and Kloner RA: Allogeneic mesenchymal stem cell
transplantation in postinfarcted rat myocardium: short- and
long-term effects. Circulation. 112:214–223. 2005. View Article : Google Scholar : PubMed/NCBI
|
5
|
Toma C, Pittenger MF, Cahill KS, Byrne BJ
and Kessler PD: Human mesenchymal stem cells differentiate to a
cardiomyocyte phenotype in the adult murine heart. Circulation.
105:93–98. 2002. View Article : Google Scholar : PubMed/NCBI
|
6
|
Minamino T and Kitakaze M: ER stress in
cardiovascular disease. J Mol Cell Cardiol. 48:1105–1110. 2010.
View Article : Google Scholar
|
7
|
Hou M, Liu J, Liu F, Liu K and Yu B: C1q
tumor necrosis factor-related protein-3 protects mesenchymal stem
cells against hypoxia- and serum deprivation-induced apoptosis
through the phosphoinositide 3-kinase/Akt pathway. Int J Mol Med.
33:97–104. 2014.
|
8
|
Mangi AA, Noiseux N, Kong D, He H, Rezvani
M, Ingwall JS and Dzau VJ: Mesenchymal stem cells modified with Akt
prevent remodeling and restore performance of infarcted hearts. Nat
Med. 9:1195–1201. 2003. View
Article : Google Scholar : PubMed/NCBI
|
9
|
Hou M, Cui J, Liu J, Liu F, Jiang R, Liu
K, Wang Y, Yin L, Liu W and Yu B: Angiopoietin-like 4 confers
resistance to hypoxia/serum deprivation-induced apoptosis through
PI3K/Akt and ERK1/2 signaling pathways in mesenchymal stem cells.
PLoS One. 9:e858082014. View Article : Google Scholar : PubMed/NCBI
|
10
|
Willms B, Werner J, Holst JJ, Orskov C,
Creutzfeldt W and Nauck MA: Gastric emptying, glucose responses,
and insulin secretion after a liquid test meal: effects of
exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2
(noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab.
81:327–332. 1996.PubMed/NCBI
|
11
|
Xu G, Stoffers DA, Habener JF and
Bonner-Weir S: Exendin-4 stimulates both beta-cell replication and
neogenesis, resulting in increased beta-cell mass and improved
glucose tolerance in diabetic rats. Diabetes. 48:2270–2276. 1999.
View Article : Google Scholar : PubMed/NCBI
|
12
|
DeFronzo RA, Ratner RE, Han J, Kim DD,
Fineman MS and Baron AD: Effects of exenatide (exendin-4) on
glycemic control and weight over 30 weeks in metformin-treated
patients withtype 2 diabetes. Diabetes Care. 28:1092–1100. 2005.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Sonne DP, Engstrøm T and Treiman M:
Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36)
amide against ischemia-reperfusion injury in rat heart. Regul Pept.
146:243–249. 2008. View Article : Google Scholar
|
14
|
Lee CH, Yan B, Yoo KY, Choi JH, Kwon SH,
Her S, Sohn Y, Hwang IK, Cho JH, Kim YM and Won MH:
Ischemia-induced changes in glucagon-like peptide-1 receptor and
neuroprotective effect of its agonist, exendin-4, in experimental
transient cerebral ischemia. J Neurosci Res. 89:1103–1113. 2011.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Arakawa M, Mita T, Azuma K, Ebato C, Goto
H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R and Watada H:
Inhibition of monocyte adhesion to endothelial cells and
attenuation of atherosclerotic lesion by a glucagon-like peptide-1
receptor agonist, exendin-4. Diabetes. 59:1030–1037. 2010.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Younce CW, Burmeister MA and Ayala JE:
Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis
via inhibition of endoplasmic reticulum stress and activation of
SERCA2a. Am J Physiol Cell Physiol. 304:C508–C518. 2013. View Article : Google Scholar : PubMed/NCBI
|
17
|
Marzioni M, Alpini G, Saccomanno S,
Candelaresi C, Venter J, Rychlicki C, Fava G, Francis H, Trozzi L
and Benedetti A: Exendin-4, a glucagon-like peptide 1 receptor
agonist, protects cholangiocytes from apoptosis. Gut. 58:990–997.
2009. View Article : Google Scholar :
|
18
|
Ferdaoussi M, Abdelli S, Yang J-Y, Cornu
M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber
G and Abderrahmani A: Exendin-4 protects β-cells from interleukin-1
β-induced apoptosis by interfering with the c-Jun NH2-terminal
kinase pathway. Diabetes. 57:1205–1215. 2008. View Article : Google Scholar : PubMed/NCBI
|
19
|
Lee J, Hong SW, Park SE, Rhee EJ, Park CY,
Oh KW, Park SW and Lee WY: Exendin-4 attenuates endoplasmic
reticulum stress through a SIRT1-dependent mechanism. Cell Stress
Chaperones. 19:649–656. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Clark JD, Gebhart GF, Gonder JC, Keeling
ME and Kohn DF: The 1996 guide for the care and use of laboratory
animals. ILAR J. 38:41–48. 1997. View Article : Google Scholar
|
21
|
Walter P and Ron D: The unfolded protein
response: from stress pathway to homeostatic regulation. Science.
334:1081–1086. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Cao J, Dai D-L, Yao L, Yu H-H, Ning B,
Zhang Q, Chen J, Cheng WH, Shen W and Yang ZX: Saturated fatty acid
induction of endoplasmic reticulum stress and apoptosis in human
liver cells via the PERK/ATF4/CHOP signaling pathway. Mol Cell
Biochem. 364:115–129. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Drucker DJ: Glucagon-like peptides:
regulators of cell proliferation, differentiation, and apoptosis.
Mol Endocrinol. 17:161–171. 2003. View Article : Google Scholar : PubMed/NCBI
|
24
|
Parekkadan B and Milwid JM: Mesenchymal
stem cells as therapeutics. Annu Rev Biomed Eng. 12:87–117. 2010.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Lipinski MJ, Biondi-Zoccai GG, Abbate A,
Khianey R, Sheiban I, Bartunek J, Vanderheyden M, Kim HS, Kang HJ,
Strauer BE and Vetrovec GW: Impact of intracoronary cell therapy on
left ventricular function in the setting of acute myocardial
infarction: a collaborative systematic review and meta-analysis of
controlled clinical trials. J Am Coll Cardiol. 50:1761–1767. 2007.
View Article : Google Scholar : PubMed/NCBI
|
26
|
van der Bogt KE, Schrepfer S, Yu J, Sheikh
AY, Hoyt G, Govaert JA, Velotta JB, Contag CH, Robbins RC and Wu
JC: Comparison of transplantation of adipose tissue- and bone
marrow-derived mesenchymal stem cells in the infarcted heart.
Transplantation. 87:642–652. 2009. View Article : Google Scholar : PubMed/NCBI
|
27
|
Szegezdi E, Duffy A, O'Mahoney ME, Logue
SE, Mylotte LA, O'brien T and Samali A: ER stress contributes to
ischemia-induced cardiomyocyte apoptosis. Biochem Biophys Res
Commun. 349:1406–1411. 2006. View Article : Google Scholar : PubMed/NCBI
|
28
|
Okada K, Minamino T, Tsukamoto Y, Liao Y,
Tsukamoto O, Takashima S, Hirata A, Fujita M, Nagamachi Y, Nakatani
T, et al: Prolonged endoplasmic reticulum stress in hypertrophic
and failing heart after aortic constriction: possible contribution
of endoplasmic reticulum stress to cardiac myocyte apoptosis.
Circulation. 110:705–712. 2004. View Article : Google Scholar : PubMed/NCBI
|
29
|
Hillion JA, Takahashi K, Maric D, Ruetzler
C, Barker JL and Hallenbeck JM: Development of an ischemic
tolerance model in a PC12 cell line. J Cereb Blood Flow Metab.
25:154–162. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Badiola N, Penas C, Miñano-Molina A,
Barneda-Zahonero B, Fadó R, Sánchez-Opazo G, Comella JX, Sabriá J,
Zhu C, Blomgren K, et al: Induction of ER stress in response to
oxygen-glucose deprivation of cortical cultures involves the
activation of the PERK and IRE-1 pathways and of caspase-12. Cell
Death Dis. 2:e1492011. View Article : Google Scholar : PubMed/NCBI
|
31
|
Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh
Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y and Niki I:
Protection of pancreatic beta-cells by exendin-4 may involve the
reduction of endoplasmic reticulum stress; in vivo and in vitro
studies. J Endocrinol. 193:65–74. 2007. View Article : Google Scholar : PubMed/NCBI
|
32
|
Liu J, Wang H, Wang Y, Yin Y, Wang L, Liu
Z, Yang J, Chen Y and Wang C: Exendin-4 pretreated adipose derived
stem cells are resistant to oxidative stress and improve cardiac
performance via enhanced adhesion in the infarcted heart. PLoS One.
9:e997562014. View Article : Google Scholar : PubMed/NCBI
|
33
|
Wright EJ, Farrell KA, Malik N, Kassem M,
Lewis AL, Wallrapp C and Holt CM: Encapsulated glucagon-like
peptide-1-producing mesenchymal stem cells have a beneficial effect
on failing pig hearts. Stem Cells Transl Med. 1:759–769. 2012.
View Article : Google Scholar : PubMed/NCBI
|
34
|
Favaro E, Granata R, Miceli I, Baragli A,
Settanni F, Cavallo Perin P, Ghigo E, Camussi G and Zanone MM: The
ghrelin gene products and exendin-4 promote survival of human
pancreatic islet endothelial cells inhyperglycaemic conditions,
through phosphoinositide 3-kinase/Akt, extracellular signal-related
kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling
pathways. Diabetologia. 55:1058–1070. 2012. View Article : Google Scholar : PubMed/NCBI
|
35
|
Oyadomari S and Mori M: Roles of
CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ.
11:381–389. 2004. View Article : Google Scholar
|
36
|
Zinszner H, Kuroda M, Wang X, Batchvarova
N, Lightfoot RT, Remotti H, Stevens JL and Ron D: CHOP is
implicated in programmed cell death in response to impaired
function of the endoplasmic reticulum. Genes Dev. 12:982–995. 1998.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Marciniak SJ, Yun CY, Oyadomari S, Novoa
I, Zhang Y, Jungreis R, Nagata K, Harding HP and Ron D: CHOP
induces death by promoting protein synthesis and oxidation in the
stressed endoplasmic reticulum. Genes Dev. 18:3066–3077. 2004.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Cunha DA, Ladrière L, Ortis F,
Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL and
Cnop M: Glucagon-like peptide-1 agonists protect pancreatic β-cells
from lipotoxic endoplasmic reticulum stress through upregulation of
BiP and JunB. Diabetes. 58:2851–2862. 2009. View Article : Google Scholar : PubMed/NCBI
|