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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2016 Volume 37 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle

Arunava Bandyopadhaya, Caterina Constantinou, Nikolaos Psychogios, Ryusuke Ueki, Shingo Yasuhara, J. A. Jeevendra Martyn, Julie Wilhelmy, Michael Mindrinos, Laurence G. Rahme, A. Aria Tzika
Pages: 867-878
Published online on: 12 February 2016

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Article Open Access

The human ovarian cancer cell line CABA I: A peculiar genetic evolution

Ilaria Giusti, Carla Cervelli, Sandra D'Ascenzo, Marianna Di Francesco, Claudio Ligas, Elvira D'Alessandro, Franco Papola, Vincenza Dolo
Pages: 879-888
Published online on: 25 February 2016

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Article Open Access

Exendin-4 protects bone marrow-derived mesenchymal stem cells against oxygen/glucose and serum deprivation-induced apoptosis through the activation of the cAMP/PKA signaling pathway and the attenuation of ER stress

Jieqiong He, Chao Wang, Yunpeng Sun, Bo Lu, Jinjin Cui, Nana Dong, Maomao Zhang, Youbing Liu, Bo Yu
Pages: 889-900
Published online on: 29 February 2016

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Article Open Access

Linarin promotes osteogenic differentiation by activating the BMP-2/RUNX2 pathway via protein kinase A signaling

Jia Li, Lingyu Hao, Junhua Wu, Jiquan Zhang, Jiansheng Su
Pages: 901-910
Published online on: 18 February 2016

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Article Open Access

Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signaling

Wen Wu, Daimin Zhang, Daorong Pan, Guangfeng Zuo, Xiaomin Ren, Shaoliang Chen
Pages: 911-920
Published online on: 18 February 2016

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Article Open Access

Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury

Yan Feng, Ying Cui, Jun-Ling Gao, Ming-Hang Li, Ran Li, Xiao-Hua Jiang, Yan-Xia Tian, Kai-Jie Wang, Chang-Meng Cui, Jian-Zhong Cui
Pages: 921-930
Published online on: 19 February 2016

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Article Open Access

MicroRNA-29a induces insulin resistance by targeting PPARδ in skeletal muscle cells

Yuehua Zhou, Pingqing Gu, Weijie Shi, Jingyun Li, Qun Hao, Xiaomei Cao, Qin Lu, Yu Zeng
Pages: 931-938
Published online on: 22 February 2016

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Article Open Access

Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.)in YD-15 tongue mucoepidermoid carcinoma cells

Hae Nim Lee, Hye Yeon Jang, Hyeong Jin Kim, Seong Ah Shin, Gang Sik Choo, Young Seok Park, Sang Ki Kim, Ji Youn Jung
Pages: 939-948
Published online on: 04 March 2016

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Article Open Access

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis

Feng Jin, Chong Qiao, Nannan Luan, Hui Li
Pages: 949-957
Published online on: 26 February 2016

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Article Open Access

Role of Alix in miRNA packaging during extracellular vesicle biogenesis

Alessandra Iavello, Valeska S.L. Frech, Chiara Gai, Maria Chiara Deregibus, Peter J. Quesenberry, Giovanni Camussi
Pages: 958-966
Published online on: 12 February 2016

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Article Open Access

MicroRNA-16 suppresses the activation of inflammatory macrophages in atherosclerosis by targeting PDCD4

Xue Liang, Zhao Xu, Meng Yuan, Yue Zhang, Bo Zhao, Junqian Wang, Aixue Zhang, Guangping Li
Pages: 967-975
Published online on: 22 February 2016

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Article Open Access

Effect of the harvest procedure and tissue site on the osteogenic function of and gene expression in human mesenchymal stem cells

Dirk Henrich, Christoph Nau, Saskia Bo Kraft, Maximilian Zollfrank, Kerstin Kontradowitz, Elsie Oppermann, Judith Schultheiss, Simon Meier, Johannes Frank, Ingo Marzi, Caroline Seebach
Pages: 976-988
Published online on: 12 February 2016

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Article Open Access

Uric acid enhances PKC-dependent eNOS phosphorylation and mediates cellular ER stress: A mechanism for uric acid-induced endothelial dysfunction

Peng Li, Lina Zhang, Mei Zhang, Changyong Zhou, Nan Lin
Pages: 989-997
Published online on: 18 February 2016

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Article Open Access

Silencing of phosphoglucose isomerase/autocrine motility factor decreases U87 human glioblastoma cell migration

Yang Li, Zhenqing Wei, Bin Dong, Zhigang Lian, Yinghui Xu
Pages: 998-1004
Published online on: 23 February 2016

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Article Open Access

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes

Yasuyuki Igarashi, Naoyuki Chosa, Shunsuke Sawada, Hisatomo Kondo, Takashi Yaegashi, Akira Ishisaki
Pages: 1005-1013
Published online on: 25 February 2016

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Article Open Access

Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response

Haige Zhao, Sijing Hao, Hongfei Xu, Liang Ma, Zheng Zhang, Yiming Ni, Luyang Yu
Pages: 1014-1022
Published online on: 25 February 2016

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Article Open Access

Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway

Ae Sin Lee, Yu Jin Jung, Tùng Nguyễn Thanh, Sik Lee, Won Kim, Kyung Pyo Kang, Sung Kwang Park
Pages: 1023-1029
Published online on: 04 March 2016

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Article

miR-409-3p sensitizes colon cancer cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy

Shifan Tan, Huijuan Shi, Mingchen Ba, Shengqv Lin, Hongsheng Tang, Xiaoqi Zeng, Xiangliang Zhang
Pages: 1030-1038
Published online on: 18 February 2016

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Article

LKB1 inhibits the proliferation of gastric cancer cells by suppressing the nuclear translocation of Yap and β-catenin

Lian-Gang Ma, Shi-Bo Bian, Jian-Xin Cui, Hong-Qing Xi, Ke-Cheng Zhang, Hong-Zhen Qin, Xiao-Ming Zhu, Lin Chen
Pages: 1039-1048
Published online on: 19 February 2016

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Article

SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

Ying-Wei Ding, Guang-Ju Zhao, Xiao-Lin Li, Guang-Liang Hong, Meng-Fang Li, Qiao-Meng Qiu, Bin Wu, Zhong-Qiu Lu
Pages: 1049-1058
Published online on: 25 February 2016

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Article

Atorvastatin ameliorates early brain injury after subarachnoid hemorrhage via inhibition of AQP4 expression in rabbits

Jun-Hui Chen, Li-Kun Yang, Lei Chen, Yu-Hai Wang, Yun Wu, Bing-Jie Jiang, Jie Zhu, Pei-Pei Li
Pages: 1059-1066
Published online on: 25 February 2016

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Article

Downregulation of microRNA-196a enhances the sensitivity of non-small cell lung cancer cells to cisplatin treatment

Qian Li, Zailiang Yang, Mingyan Chen, Ying Liu
Pages: 1067-1074
Published online on: 01 March 2016

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Article

Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway

Wencheng Yang, Yan Yang, Jian-Yi Yang, Ming Liang, Jiangtao Song
Pages: 1075-1082
Published online on: 22 February 2016

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Article

iTRAQ-based quantitative proteomic analysis of the anti-apoptotic effect of hyperin, which is mediated by Mcl-1 and Bid, in H2O2-injured EA.hy926 cells

Xiao-Xia Liu, Li Tang, Rui Ge, Jian-Kuan Li, Ya Kang, Mei-Xia Zhu, Qing-Shan Li, Xu-Liang Hao
Pages: 1083-1090
Published online on: 29 February 2016

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Article

Clausena anisata-mediated protection against lipopolysaccharide-induced acute lung injury in mice

Chan-Mi Jeon, In-Sik Shin, Na-Rae Shin, Ju-Mi Hong, Ok-Kyoung Kwon, Jung-Hee Kim, Sei-Ryang Oh, Tran-The Bach, Do-Van Hai, Bui-Hong Quang, Sang-Ho Choi, Joongku Lee, Pyung-Keun Myung, Kyung-Seop Ahn
Pages: 1091-1098
Published online on: 03 March 2016

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Article

The inhibitory effect of A20 on the inflammatory reaction of epidermal keratinocytes

Kyung-Cheol Sohn, Seung Ju Back, Dae-Kyoung Choi, Jung-Min Shin, Sue Jeong Kim, Myung Im, Young Lee, Young-Joon Seo, Tae-Jin Yoon, Young Ho Lee, Jeung-Hoon Lee, Chang Deok Kim
Pages: 1099-1104
Published online on: 03 March 2016

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Article

The mechanisms of substance P-mediated migration of bone marrow-derived mesenchymal stem cell-like ST2 cells

Maria Jose Dubon, Ki-Sook Park
Pages: 1105-1111
Published online on: 19 February 2016

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Article

miR-542-3p inhibits the growth and invasion of colorectal cancer cells through targeted regulation of cortactin

Hao-Cheng Long, Xia Gao, Chang-Jiang Lei, Bin Zhu, Lei Li, Cheng Zeng, Jian-Bin Huang, Jia-Rui Feng
Pages: 1112-1118
Published online on: 25 February 2016

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Article

Rosa hybrida extract suppresses vascular smooth muscle cell responses by the targeting of signaling pathways, cell cycle regulation and matrix metalloproteinase-9 expression

Se-Jung Lee, Se Yeon Won, Sung Lyea Park, Jun-Hui Song, Dae-Hwa Noh, Hong-Man Kim, Chang Shik Yin, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1119-1126
Published online on: 25 February 2016

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Article

Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice

Shirin Elhaik Goldman, Shahar Dotan, Amir Talias, Amit Lilo, Shalhevet Azriel, Itay Malka, Maxim Portnoi, Ariel Ohayon, Daniel Kafka, Ronald Ellis, Moshe Elkabets, Angel Porgador, Ditza Levin, Rosa Azhari, Edwin Swiatlo, Eduard Ling, Galia Feldman, Michael Tal, Ron Dagan, Yaffa Mizrachi Nebenzahl
Pages: 1127-1138
Published online on: 01 March 2016

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Article

Slit-miR-218-Robo axis regulates retinal neovascularization

Yichun Kong, Bei Sun, Quanhong Han, Shuang Han, Yuchuan Wang, Ying Chen
Pages: 1139-1145
Published online on: 29 February 2016

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Review

Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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Article Open Access

IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Review Open Access

Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Review Open Access

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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Review Open Access

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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Correction Open Access

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Review Open Access

Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Review Open Access

Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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July-2026 Volume 58 Issue 1

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Review Open Access

Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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Article Open Access

CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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Article Open Access

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Review Open Access

Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Review Open Access

Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Review Open Access

Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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