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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2016 Volume 37 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle

Arunava Bandyopadhaya, Caterina Constantinou, Nikolaos Psychogios, Ryusuke Ueki, Shingo Yasuhara, J. A. Jeevendra Martyn, Julie Wilhelmy, Michael Mindrinos, Laurence G. Rahme, A. Aria Tzika
Pages: 867-878
Published online on: 12 February 2016

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Article Open Access

The human ovarian cancer cell line CABA I: A peculiar genetic evolution

Ilaria Giusti, Carla Cervelli, Sandra D'Ascenzo, Marianna Di Francesco, Claudio Ligas, Elvira D'Alessandro, Franco Papola, Vincenza Dolo
Pages: 879-888
Published online on: 25 February 2016

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Article Open Access

Exendin-4 protects bone marrow-derived mesenchymal stem cells against oxygen/glucose and serum deprivation-induced apoptosis through the activation of the cAMP/PKA signaling pathway and the attenuation of ER stress

Jieqiong He, Chao Wang, Yunpeng Sun, Bo Lu, Jinjin Cui, Nana Dong, Maomao Zhang, Youbing Liu, Bo Yu
Pages: 889-900
Published online on: 29 February 2016

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Article Open Access

Linarin promotes osteogenic differentiation by activating the BMP-2/RUNX2 pathway via protein kinase A signaling

Jia Li, Lingyu Hao, Junhua Wu, Jiquan Zhang, Jiansheng Su
Pages: 901-910
Published online on: 18 February 2016

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Article Open Access

Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signaling

Wen Wu, Daimin Zhang, Daorong Pan, Guangfeng Zuo, Xiaomin Ren, Shaoliang Chen
Pages: 911-920
Published online on: 18 February 2016

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Article Open Access

Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury

Yan Feng, Ying Cui, Jun-Ling Gao, Ming-Hang Li, Ran Li, Xiao-Hua Jiang, Yan-Xia Tian, Kai-Jie Wang, Chang-Meng Cui, Jian-Zhong Cui
Pages: 921-930
Published online on: 19 February 2016

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Article Open Access

MicroRNA-29a induces insulin resistance by targeting PPARδ in skeletal muscle cells

Yuehua Zhou, Pingqing Gu, Weijie Shi, Jingyun Li, Qun Hao, Xiaomei Cao, Qin Lu, Yu Zeng
Pages: 931-938
Published online on: 22 February 2016

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Article Open Access

Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.)in YD-15 tongue mucoepidermoid carcinoma cells

Hae Nim Lee, Hye Yeon Jang, Hyeong Jin Kim, Seong Ah Shin, Gang Sik Choo, Young Seok Park, Sang Ki Kim, Ji Youn Jung
Pages: 939-948
Published online on: 04 March 2016

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Article Open Access

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis

Feng Jin, Chong Qiao, Nannan Luan, Hui Li
Pages: 949-957
Published online on: 26 February 2016

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Article Open Access

Role of Alix in miRNA packaging during extracellular vesicle biogenesis

Alessandra Iavello, Valeska S.L. Frech, Chiara Gai, Maria Chiara Deregibus, Peter J. Quesenberry, Giovanni Camussi
Pages: 958-966
Published online on: 12 February 2016

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Article Open Access

MicroRNA-16 suppresses the activation of inflammatory macrophages in atherosclerosis by targeting PDCD4

Xue Liang, Zhao Xu, Meng Yuan, Yue Zhang, Bo Zhao, Junqian Wang, Aixue Zhang, Guangping Li
Pages: 967-975
Published online on: 22 February 2016

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Article Open Access

Effect of the harvest procedure and tissue site on the osteogenic function of and gene expression in human mesenchymal stem cells

Dirk Henrich, Christoph Nau, Saskia Bo Kraft, Maximilian Zollfrank, Kerstin Kontradowitz, Elsie Oppermann, Judith Schultheiss, Simon Meier, Johannes Frank, Ingo Marzi, Caroline Seebach
Pages: 976-988
Published online on: 12 February 2016

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Article Open Access

Uric acid enhances PKC-dependent eNOS phosphorylation and mediates cellular ER stress: A mechanism for uric acid-induced endothelial dysfunction

Peng Li, Lina Zhang, Mei Zhang, Changyong Zhou, Nan Lin
Pages: 989-997
Published online on: 18 February 2016

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Article Open Access

Silencing of phosphoglucose isomerase/autocrine motility factor decreases U87 human glioblastoma cell migration

Yang Li, Zhenqing Wei, Bin Dong, Zhigang Lian, Yinghui Xu
Pages: 998-1004
Published online on: 23 February 2016

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Article Open Access

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes

Yasuyuki Igarashi, Naoyuki Chosa, Shunsuke Sawada, Hisatomo Kondo, Takashi Yaegashi, Akira Ishisaki
Pages: 1005-1013
Published online on: 25 February 2016

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Article Open Access

Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response

Haige Zhao, Sijing Hao, Hongfei Xu, Liang Ma, Zheng Zhang, Yiming Ni, Luyang Yu
Pages: 1014-1022
Published online on: 25 February 2016

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Article Open Access

Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway

Ae Sin Lee, Yu Jin Jung, Tùng Nguyễn Thanh, Sik Lee, Won Kim, Kyung Pyo Kang, Sung Kwang Park
Pages: 1023-1029
Published online on: 04 March 2016

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Article

miR-409-3p sensitizes colon cancer cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy

Shifan Tan, Huijuan Shi, Mingchen Ba, Shengqv Lin, Hongsheng Tang, Xiaoqi Zeng, Xiangliang Zhang
Pages: 1030-1038
Published online on: 18 February 2016

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Article

LKB1 inhibits the proliferation of gastric cancer cells by suppressing the nuclear translocation of Yap and β-catenin

Lian-Gang Ma, Shi-Bo Bian, Jian-Xin Cui, Hong-Qing Xi, Ke-Cheng Zhang, Hong-Zhen Qin, Xiao-Ming Zhu, Lin Chen
Pages: 1039-1048
Published online on: 19 February 2016

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Article

SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

Ying-Wei Ding, Guang-Ju Zhao, Xiao-Lin Li, Guang-Liang Hong, Meng-Fang Li, Qiao-Meng Qiu, Bin Wu, Zhong-Qiu Lu
Pages: 1049-1058
Published online on: 25 February 2016

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Article

Atorvastatin ameliorates early brain injury after subarachnoid hemorrhage via inhibition of AQP4 expression in rabbits

Jun-Hui Chen, Li-Kun Yang, Lei Chen, Yu-Hai Wang, Yun Wu, Bing-Jie Jiang, Jie Zhu, Pei-Pei Li
Pages: 1059-1066
Published online on: 25 February 2016

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Article

Downregulation of microRNA-196a enhances the sensitivity of non-small cell lung cancer cells to cisplatin treatment

Qian Li, Zailiang Yang, Mingyan Chen, Ying Liu
Pages: 1067-1074
Published online on: 01 March 2016

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Article

Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway

Wencheng Yang, Yan Yang, Jian-Yi Yang, Ming Liang, Jiangtao Song
Pages: 1075-1082
Published online on: 22 February 2016

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Article

iTRAQ-based quantitative proteomic analysis of the anti-apoptotic effect of hyperin, which is mediated by Mcl-1 and Bid, in H2O2-injured EA.hy926 cells

Xiao-Xia Liu, Li Tang, Rui Ge, Jian-Kuan Li, Ya Kang, Mei-Xia Zhu, Qing-Shan Li, Xu-Liang Hao
Pages: 1083-1090
Published online on: 29 February 2016

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Article

Clausena anisata-mediated protection against lipopolysaccharide-induced acute lung injury in mice

Chan-Mi Jeon, In-Sik Shin, Na-Rae Shin, Ju-Mi Hong, Ok-Kyoung Kwon, Jung-Hee Kim, Sei-Ryang Oh, Tran-The Bach, Do-Van Hai, Bui-Hong Quang, Sang-Ho Choi, Joongku Lee, Pyung-Keun Myung, Kyung-Seop Ahn
Pages: 1091-1098
Published online on: 03 March 2016

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Article

The inhibitory effect of A20 on the inflammatory reaction of epidermal keratinocytes

Kyung-Cheol Sohn, Seung Ju Back, Dae-Kyoung Choi, Jung-Min Shin, Sue Jeong Kim, Myung Im, Young Lee, Young-Joon Seo, Tae-Jin Yoon, Young Ho Lee, Jeung-Hoon Lee, Chang Deok Kim
Pages: 1099-1104
Published online on: 03 March 2016

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Article

The mechanisms of substance P-mediated migration of bone marrow-derived mesenchymal stem cell-like ST2 cells

Maria Jose Dubon, Ki-Sook Park
Pages: 1105-1111
Published online on: 19 February 2016

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Article

miR-542-3p inhibits the growth and invasion of colorectal cancer cells through targeted regulation of cortactin

Hao-Cheng Long, Xia Gao, Chang-Jiang Lei, Bin Zhu, Lei Li, Cheng Zeng, Jian-Bin Huang, Jia-Rui Feng
Pages: 1112-1118
Published online on: 25 February 2016

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Article

Rosa hybrida extract suppresses vascular smooth muscle cell responses by the targeting of signaling pathways, cell cycle regulation and matrix metalloproteinase-9 expression

Se-Jung Lee, Se Yeon Won, Sung Lyea Park, Jun-Hui Song, Dae-Hwa Noh, Hong-Man Kim, Chang Shik Yin, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1119-1126
Published online on: 25 February 2016

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Article

Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice

Shirin Elhaik Goldman, Shahar Dotan, Amir Talias, Amit Lilo, Shalhevet Azriel, Itay Malka, Maxim Portnoi, Ariel Ohayon, Daniel Kafka, Ronald Ellis, Moshe Elkabets, Angel Porgador, Ditza Levin, Rosa Azhari, Edwin Swiatlo, Eduard Ling, Galia Feldman, Michael Tal, Ron Dagan, Yaffa Mizrachi Nebenzahl
Pages: 1127-1138
Published online on: 01 March 2016

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Article

Slit-miR-218-Robo axis regulates retinal neovascularization

Yichun Kong, Bei Sun, Quanhong Han, Shuang Han, Yuchuan Wang, Ying Chen
Pages: 1139-1145
Published online on: 29 February 2016

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Journal Cover
December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Tracing the malignant trajectory of microplastics and nanoplastics: Biological pathways potentially implicated in carcinogenesis (Review)

Mary A. Vasilopoulou, Maria Adamaki, Panagiotis Zoumpourlis, Demetrios A. Spandidos, Dimosthenis Sarigiannis, Vassilis Zoumpourlis
Article Number: 376
Published online on: 10 November 2026

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Piezo1 in acute and critical illnesses: From mechanosensing to organ dysfunction (Review)

Li Zhang, Hong Gu, Yibin Zhu, Lulu Tang, Jiaxing An, Jiaxing Zhu, Hai Jin, Biguang Tuo
Article Number: 375
Published online on: 10 November 2026

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Transmembrane proteins across cellular membranes: Emerging roles in non‑cancerous diseases (Review)

Pei-Feng Liu, Chia-Hsuan Chang, Hsing-Hsiang Wang, Chih-Wen Shu, Yung-Fu Chang
Article Number: 374
Published online on: 09 November 2026

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MEX3B leads to aberrant expression of VCAN, aggravating the thoracic aortic dissection by contributing to the phenotype transformation of VSMCs

Jianmao Hong, Bijun Xu, Shiqiang Wang, Fan He
Article Number: 373
Published online on: 06 November 2026

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From crystals to damage: The emerging role of ferroptosis in calcium oxalate nephropathy (Review)

Zhu Wang, Changzhi Xu, Qiong Deng, Yin Zhang, Hui Liang
Article Number: 372
Published online on: 05 November 2026

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Orm1 protects steatotic livers against ischaemia‑reperfusion injury by stabilising Prdx1 and activating the Pi3k/Akt axis

Yuming Wang, Ruidong Ding, Hailun Cai, Huan Liu, Yilin Wang, Xiangheng Cai, Jinzhen Cai
Article Number: 371
Published online on: 05 November 2026

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Article Open Access

Emodin ameliorates diabetic cardiomyopathy by regulating mitochondrial dynamics of fission and fusion and ferroptosis through the AHR‑Nrf2 pathway

Xinrou Yu, Haifei Lou, Jiedong Zhou, Hui Lin, Jinjing Yang, Jufang Chi
Article Number: 370
Published online on: 05 November 2026

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Macrophage polarization reprogramming by resveratrol: A novel mechanism for protecting the intestinal mucosal barrier in sepsis (Review)

Yang Tan, Jin Xia, Chuan-Yun Qian, Mei-Xian Su, Shu-Ji Gao, Yan-Lin Zhu, Xiao-Yu Yang, Wei Zhang, Ming-Wei Liu
Article Number: 369
Published online on: 04 November 2026

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Harnessing the power of Scutellaria baicalensis: Advances in active compounds and their impact on skeletal system diseases (Review)

Weichao Sun, Yuqi Wu, Liangyu Chen, Yan Ni, Chunling Zhao, Wei Sun, Yinxing Cui, Qian Yi
Article Number: 368
Published online on: 04 November 2026

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Protein S‑palmitoylation in T cell‑mediated antitumor immunity: Context‑dependent mechanisms and therapeutic opportunities (Review)

Shiting Wang, Rui Xu, Sikan Jin, Ting Yu, Ming Qin, Lin Xu, Xianyao Wang
Article Number: 367
Published online on: 04 November 2026

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Fatty acid‑binding proteins at the inflammation‑cancer interface: Isoform‑specific metabolic‑immune mechanisms and therapeutic implications (Review)

Young-Sool Hah, Young-Tae Ju, Seung-Jun Lee, Jeongyun Hwang, Seung-Jin Kwag
Article Number: 366
Published online on: 04 November 2026

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Role of microglia in neuromyelitis optica (Review)

Yuan Zhang, Jian-Bin Hong, Ming-Wei Liu, Lin-Ming Zhang
Article Number: 365
Published online on: 03 November 2026

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Roles of TRIM proteins in cardiovascular diseases: From pathogenesis to therapeutic targeting (Review)

Fengmei Wang, Zhibo Xing, Yujuan Gao, Yanhong Gai
Article Number: 364
Published online on: 02 November 2026

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[Corrigendum] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy

Liangchun Yang, Minghua Yang, Hong Zhang, Zhuo Wang, Yan Yu, Min Xie, Mingyi Zhao, Liying Liu, Lizhi Cao
Article Number: 363
Published online on: 02 November 2026

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S100 proteins in kidney disease: Inflammatory biomarkers, pathogenic mechanisms and therapeutic prospects (Review)

Hongfei Wang, Zhaoyang Li, Qianqian Li, Yufang Ni, Lifeng Meng, Jianchun Li
Article Number: 362
Published online on: 30 October 2026

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Review

Mechanisms and therapeutic perspectives of mucosal glycosylation-innate immunity crosstalk in inflammatory bowel disease (Review)

Xiaowen Liu, Tao Zhang, Jiayi Jin, Yumeng Song, Mozhu Li, Haotong Zhong, Mingyue Cai, Siyuan Ding, Xiaowei Han
Article Number: 361
Published online on: 30 October 2026

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Glycolysis in pulmonary fibrosis: From drivers to therapeutic opportunities (Review)

Changhong Yao, Huanyu Yang, Mengjia Han, Qi Xu
Article Number: 360
Published online on: 29 October 2026

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Correction Open Access

[Corrigendum] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 359
Published online on: 29 October 2026

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Emerging role of non‑coding RNAs in the progression of MASLD‑driven hepatocellular carcinoma (Review)

Weihua Zheng, Caiyan An, Long Xia, Hongquan Wang, Yumin Wang, Junjing Zhang
Article Number: 358
Published online on: 27 October 2026

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Targeting ferroptosis in metabolic dysfunction‑associated steatotic liver disease: From mechanisms to cell type‑specific therapeutic strategies (Review)

Xiang Tao, Mei Liu
Article Number: 357
Published online on: 26 October 2026

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Hormonal remodeling and molecular mechanisms in postmenopausal osteoporosis: Pathogenesis and therapeutic implications (Review)

Wenjun Liu, Zhengzheng Li, Penglin Wang, Jiahao Zeng, Haimin Zeng, Yining Xie, Ruhui Yang, Liu Yang, Sijian Lin, Chenyu Zhang
Article Number: 356
Published online on: 26 October 2026

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Correction Open Access

[Corrigendum] Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells 

Yunlu Jiang, Haiqing Liu, Bingyuan Ji, Zhengwen Wang, Chunmei Wang, Chunqing Yang, Yanyou Pan, Jing Chen, Baohua Cheng, Bo Bai
Article Number: 355
Published online on: 26 October 2026

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Mechanisms and therapeutic implications of ferritinophagy in fibrotic diseases (Review)

Siying Sun, Jie Yu, Xuemei Li, Hongfei Liao
Article Number: 354
Published online on: 23 October 2026

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Immune remodeling in inflammatory bowel disease-associated colorectal cancer: Mechanisms and immunotherapeutic implications (Review)

Tao Zhang, Zhetan Ren, Ling Wang, Ru Man, Lin Wang, Jing Wang, Xiaozhen Cheng, Jirun Peng, Yongduo Yu
Article Number: 353
Published online on: 22 October 2026

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Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review)

Jingjing Cui, Qi Cui, Jinying Dou, Xiaoyan Li, Wenlong Chang, Lanchun Shi, Liyun An
Article Number: 352
Published online on: 22 October 2026

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Article Open Access

HMGN5 promotes renal tubular inflammation and pyroptosis‑associated signaling in chronic kidney disease via the IFNAR2 axis

Xue Rong, Jing Xu, Jienan Zhang, Qi Zhang, Jiangli Wang, Guoxin Zhang, Limin Nie
Article Number: 351
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Radiation induces primary osteocyte senescence phenotype and affects osteoclastogenesis in vitro

Yuyang Wang, Linshan Xu, Jianping Wang, Jiangtao Bai, Jianglong Zhai, Guoying Zhu
Article Number: 350
Published online on: 21 October 2026

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Review Open Access

Transcription factors in liver fibrosis: Mechanistic insights and nanotechnology‑driven therapeutic strategies (Review)

Xianfei Zhou, Chongjun Yang, Zhiyong Weng, Lihua Li
Article Number: 349
Published online on: 21 October 2026

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Review Open Access

From RNA fate to cancer state transitions: m5C‑driven metabolic and immune reprogramming (Review)

Yuanli Zhou, Bolv Zhu, Xingzhou Tang, Shuishui Yin
Article Number: 348
Published online on: 20 October 2026

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Correction Open Access

[Corrigendum] Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis 

Dong Ding, Jiangbo Yan, Gangning Feng, Yong Zhou, Long Ma, Qunhua Jin
Article Number: 347
Published online on: 19 October 2026

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Review Open Access

Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Review Open Access

Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Article Open Access

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Article Open Access

Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Review Open Access

Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Review Open Access

Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Review Open Access

Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Review Open Access

Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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January-2027 Volume 59 Issue 1

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Cellular and molecular mechanisms of arrhythmogenesis in Takotsubo syndrome (Review)

Danqi Xu, Xiaohong Chen, Maolin Hao, Qianqian Xu, Binbin Zhao, Wenjun Huang, Xiaobo Zhou, Qiang Xu, Huan Lan
Article Number: 5
Published online on: 12 November 2026

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Metabolic syndrome and Alzheimer's disease: Mechanistic links and precision prevention (Review)

Hanlu Chen, Tao Ding, Yifan Zhu, Mei Yang, Fangsheng Wang, Puwen Chen, Haihong Lin, Huapei Kang, Maohong Hu, Jun Zhou, Xiaoling Wang
Article Number: 4
Published online on: 12 November 2026

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Article Open Access

Irisin alleviates oxidative stress and osteoblast apoptosis in glucocorticoid-induced rat osteonecrosis of the femoral head via the integrin αVβ5/Bach1/Nrf2 signaling pathway

Xin Zhang, Yuankai Zhang, Yan Zhao, Keke Song, Xiaofei Liu, Kai Nan, Lihong Fan
Article Number: 3
Published online on: 12 November 2026

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Expression of Concern Open Access

[Expression of Concern] Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells

Xuehua Liu, Junhua Zuo, Yuan Fang, Jing Wen, Feihong Deng, Hui Zhong, Bo Jiang, Jide Wang, Biao Nie
Article Number: 2
Published online on: 11 November 2026

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Review Open Access

Mitochondria‑associated small RNAs in breast cancer: An asymmetric evidence landscape from metabolic rewiring to immune selection (Review)

Hung-Yu Lin, Hui-Wen Ho, Hao-Wen Hsiao, Yi-Ru Shen, Hao-Yi Li, Pei-Yi Chu
Article Number: 1
Published online on: 10 November 2026

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