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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 24 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity

Hongyan Liang, Sandra O'Reilly, Youhua Liu, Roger Abounader, John Laterra, Veronica M. Maher, J. Justin McCormick
Pages: 1057-1067
Published online on: 01 May 2004

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Article

The balance between MMP-2/-9 and TIMP-1/-2 is shifted towards MMP in renal cell carcinomas and can be further disturbed by hydrogen peroxide

Bernhard Hemmerlein, Ulrike Johanns, Julia Halbfass, Tobias Böttcher, Markus Heuser, Heinz-Joachim Radzun, Paul Thelen
Pages: 1069-1076
Published online on: 01 May 2004

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Article

Immunohistochemical analysis and mutational analyses of β-catenin, Axin family and APC genes in hepatocellular carcinomas

Yasuyo Ishizaki, Satoshi Ikeda, Masahiko Fujimori, Yosuke Shimizu, Takeshi Kurihara, Toshiyuki Itamoto, Akira Kikuchi, Masazumi Okajima, Toshimasa Asahara
Pages: 1077-1083
Published online on: 01 May 2004

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Article

cDNA microarray analysis with amplified RNA after isolation of intact cellular RNA from neoplastic and non-neoplastic prostate tissue separated by laser microdissections

Paul Thelen, Peter Burfeind, Michal Grzmil, Silke Voigt, Rolf-Hermann Ringert, Bernhard Hemmerlein
Pages: 1085-1092
Published online on: 01 May 2004

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Article

Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3

Jiahua Jiang, Veronika Slivova, Tatiana Valachovicova, Kevin Harvey, Daniel Sliva
Pages: 1093-1099
Published online on: 01 May 2004

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Review

Molecular targeting for malignant gliomas (Review)

Yasuko Kondo, Emporia F. Hollingsworth, Seiji Kondo
Pages: 1101-1109
Published online on: 01 May 2004

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Article

Calbindin-D28k and calcium sensing receptor cooperate in MCF-7 human breast cancer cells

Jai Parkash, Muhammad A. Chaudhry, William B. Rhoten
Pages: 1111-1119
Published online on: 01 May 2004

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Article

Quinoxaline 1,4-dioxides are novel angiogenesis inhibitors that potentiate antitumor effects of ionizing radiation

Hala Gali-Muhtasib, Mazen Sidani, Fady Geara, Assaf-Diab Mona, Josianne Al-Hmaira, Makhluf J. Haddadin, Ghazi Zaatari
Pages: 1121-1131
Published online on: 01 May 2004

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Article

The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice

Sharmila Shankar, Thiyam Ramsing Singh, Xufeng Chen, Hitesh Thakkar, Jason Firnin, Rakesh K. Srivastava
Pages: 1133-1140
Published online on: 01 May 2004

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Article

Establishment and characterization of a cytogenetically complex Chinese multiple myeloma-derived cell line with homozygous p53 deletion and cyclin E overexpression

Suk Hang Cheng, Margaret Heung Ling Ng, Kam Sze Tsang, Kin Mang Lau, Joyce Chee Wun Chan, Herman Sung Yu Liu, Raymond Wan Chu, Cycles Suet Ping Poon, Ho Keung Ng
Pages: 1141-1148
Published online on: 01 May 2004

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Article

Cerivastatin demonstrates enhanced antitumor activity against human breast cancer cell lines when used in combination with doxorubicin or cisplatin

Katarzyna Kozar, Rafal Kaminski, Magdalena Legat, Maciej Kopec, Dominika Nowis, Janusz S. Skierski, Miroslawa Koronkiewicz, Marek Jakóbisiak, Jakub Golab
Pages: 1149-1157
Published online on: 01 May 2004

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Article

Induction of p97MAPK expression regulates collagen mediated inhibition of proliferation and migration in human squamous cell carcinoma lines

David L. Crowe
Pages: 1159-1163
Published online on: 01 May 2004

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Article

Clinicopathological states of Epstein-Barr virus-associated T/NK-cell lymphoproliferative disorders (severe chronic active EBV infection) of children and young adults

Keiko Suzuki, Koichi Ohshima, Kennosuke Karube, Junji Suzumiya, Shouichi Ohga, Shigehiko Ishihara, Kazuo Tamura, Masahiro Kikuchi
Pages: 1165-1174
Published online on: 01 May 2004

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Article

Adjuvant oral 5-fluorouracil for cervical cancer: Japanese Gynecologic Oncology Group report

Kaichiro Yamamoto, Rikuichi Izumi, Kazuo Hasegawa, Hisayoshi Nakajima, Kazutomo Ohashi, Ryuichi Kudo, Hiroyuki Okuda, Takeshi Takahashi, Hideki Origasa, Hajime Sugimori
Pages: 1175-1179
Published online on: 01 May 2004

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Article

Enhanced therapeutic effects of doxorubicin and paclitaxel in combination with liposome-entrapped ends-modified raf antisense oligonucleotide against human prostate, lung and breast tumor models

Rajshree R. Mewani, Wenhua Tang, Aquilur Rahman, Anatoly Dritschilo, Imran Ahmad, Usha N. Kasid, Prafulla C. Gokhale
Pages: 1181-1188
Published online on: 01 May 2004

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Article

Establishment and characterization of unique human gallbladder cancer cell lines

Mila Ghosh, Naoto Koike, Go Yanagimoto, Shin-Ichi Tsunoda, Sunil Kaul, Takashi Hirano, Fabian Emura, Hironobu Kashiwagi, Toru Kawamoto, Nobuhiro Ohkohchi, Kaoru Saijo, Tadao Ohno, Masanao Miwa, Takeshi Todoroki
Pages: 1189-1196
Published online on: 01 May 2004

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Article

Prognostic significance of angiogenesis evaluated by CD105 expression compared to CD31 in 905 breast carcinomas: Correlation with long-term patient outcome

Jean-Philippe Dales, Stephane Garcia, Lucile Andrac, Severine Carpentier, Olivier Ramuz, Marie-Noëlle Lavaut, Claude Allasia, Pascal Bonnier, Colette Charpin
Pages: 1197-1204
Published online on: 01 May 2004

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Article

Expression of G1 phase-related cell cycle molecules in naturally developing hepatocellular carcinoma of Long-Evans Cinnamon rats

Yuko Kita, Tsutomu Masaki, Fumi Funakoshi, Shuhei Yoshida, Misuzu Tanaka, Kazutaka Kurokohchi, Naohito Uchida, Seishiro Watanabe, Kozo Matsumoto, Shigeki Kuriyama
Pages: 1205-1211
Published online on: 01 May 2004

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Article

Introduction of p16INK4a inhibits telomerase activity through transcriptional suppression of human telomerase reverse transcriptase expression in human gliomas

Masahiro Saito, Kou Nakagawa, Katsuyuki Hamada, Susumu Hirose, Hironobu Harada, Shohei Kohno, Shigeyuki Nagato, Takanori Ohnishi
Pages: 1213-1220
Published online on: 01 May 2004

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Article

Necrotic cell death induced by photodynamic treatment of human lung adenocarcinoma A-549 cells with palladium(II)-tetraphenylporphycene

M. Cañete, C. Ortega, A. Gavaldá, J. Cristobal, A. Juarranz, S. Nonell, J. Teixidó, J. I. Borrell, A. Villanueva, S. Rello, J. C. Stockert
Pages: 1221-1228
Published online on: 01 May 2004

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Article

Smad2 mediates Erk1/2 activation by TGF-β1 in suspended, but not in adherent, gastric carcinoma cells

Mi-Sook Lee, Seong-Gyu Ko, Hwang-Phill Kim, Yong-Bae Kim, Sung-Yul Lee, Sang-Gyun Kim, Hyun-Soon Jong, Tae-You Kim, Jung Weon Lee, Yung-Jue Bang
Pages: 1229-1234
Published online on: 01 May 2004

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Article

Decreased levels of osteopontin and bone sialoprotein II are correlated with reduced proliferation, colony formation, and migration of GFP-MDA-MB-231 cells

Hassan Adwan, Tobias Bäuerle, Yousef Najajreh, Victoria Elazer, Gershon Golomb, Martin R. Berger
Pages: 1235-1244
Published online on: 01 May 2004

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Article

Down-regulation of p21Waf-1 protein facilitates IR- and UV-induced apoptosis in human squamous carcinoma cells

Shinsuke Izumaru, Nobuyuki Arima, Yasuo Toyozumi, Seiya Kato, Minoru Morimatsu, Tadashi Nakashima
Pages: 1245-1255
Published online on: 01 May 2004

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Review

Structural and functional conservation of the lgl recessive oncogenes (Review)

Kwang-Hyun Baek
Pages: 1257-1261
Published online on: 01 May 2004

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Article

Sensitivity of fresh isolates of soft tissue sarcoma, osteosarcoma and giant cell tumour cells to Apo2L/TRAIL and doxorubicin

S. Bouralexis, M. Clayer, G. J. Atkins, A. Labrinidis, S. Hay, S. Graves, D. M. Findlay, A. Evdokiou
Pages: 1263-1270
Published online on: 01 May 2004

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Article

Loss of heterozygosity at chromosome 9q22-31 is a frequent and early event in ovarian tumors

Jennifer Byrom, Vivek Mudaliar, Charles W. Redman, Peter Jones, Richard C. Strange, Paul R. Hoban
Pages: 1271-1277
Published online on: 01 May 2004

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Article

Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil

Paula M. De Angelis, Bjørg Fjell, Katherine L. Kravik, Terje Haug, Siv H. Tunheim, Wenche Reichelt, Marzieh Beigi, Ole Petter Clausen, Eivind Galteland, Trond Stokke
Pages: 1279-1288
Published online on: 01 May 2004

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Article

Specific tumour localisation of a huA33 antibody - carboxypeptidase A conjugate and activation of methotrexate-phenylalanine

P. Markus Deckert, William G. Bornmann, Gerd Ritter, Clarence Williams, Juergen Franke, Ulrich Keilholz, Eckhard Thiel, Lloyd J. Old, Joseph R. Bertino, Sydney Welt
Pages: 1289-1295
Published online on: 01 May 2004

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Article

Reduction of CWR22 prostate tumor xenograft growth by combined tamoxifen-quercetin treatment is associated with inhibition of angiogenesis and cellular proliferation

Zeng-Shuan Ma, Thanh Hoa Huynh, Chee Pang Ng, Phuc Tien Do, Thanh Hung Nguyen, Hung Huynh
Pages: 1297-1304
Published online on: 01 May 2004

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Article

Identification of a functional peroxisome proliferator activated receptor response element in the 3' untranslated region of the human bcl-2 gene

Brent D. Butts, Nhan L. Tran, Margaret M. Briehl
Pages: 1305-1310
Published online on: 01 May 2004

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Article

Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells

Marie-Eve St-Germain, Veronique Gagnon, Isabelle Mathieu, Sophie Parent, Eric Asselin
Pages: 1311-1324
Published online on: 01 May 2004

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Article

Gonadotropin-induced gene regulation in human granulosa cells obtained from IVF patients: Modulation of genes coding for growth factors and their receptors and genes involved in cancer and other diseases

E. Rimon, R. Sasson, A. Dantes, A. Land-Bracha, A. Amsterdam
Pages: 1325-1338
Published online on: 01 May 2004

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Article

Identification and characterization of human FOXN5 and rat Foxn5 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 1339-1344
Published online on: 01 May 2004

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Article

Identification and characterization of TMEM16E and TMEM16F genes in silico

Masuko Katoh, Masaru Katoh
Pages: 1345-1349
Published online on: 01 May 2004

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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