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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2008 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

The use of monoclonal antibodies for the treatment of epithelial ovarian cancer (review)

Angèle L.M. Oei, Fred C.G.J. Sweep, Chris M.G. Thomas, Otto C. Boerman, Leon F.A.G. Massuger
Pages: 1145-1157
Published online on: 01 June 2008

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Article Open Access

Protective effect of hyaluronate on oxidative DNA damage in WI-38 and A549 cells

Hong Zhao, Toshiki Tanaka, Vadim Mitlitski, Julie Heeter, Endre A. Balazs, Zbigniew Darzynkiewicz
Pages: 1159-1167
Published online on: 01 June 2008

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Article

Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression

Z. Milicevic, D. Bogojevic, M. Mihailovic, M. Petrovic, Z. Krivokapic
Pages: 1169-1178
Published online on: 01 June 2008

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Article

Development of an optimized conditionally replicative adenoviral agent for ovarian cancer

Zeng B. Zhu, Baogen Lu, Miey Park, Sharmila K. Makhija, Thomas M. Numnum, James E. Kendrick, Minghui Wang, Yuko Tsuruta, Paul Fisher, Ronald D. Alvarez, Fen Zhou, Gene P. Siegal, Hongju Wu, David T. Curiel
Pages: 1179-1188
Published online on: 01 June 2008

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Article

Mitotic catastrophe induced in HeLa cells by photodynamic treatment with Zn(II)-phthalocyanine

Santiago Rello-Varona, Juan Carlos Stockert, Magdalena Cañete, Pilar Acedo, Ángeles Villanueva
Pages: 1189-1196
Published online on: 01 June 2008

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Article

Substances from the medicinal mushroom Daedalea gibbosa inhibit kinase activity of native and T315I mutated Bcr-Abl

Majed Yassin, Solomon P. Wasser, Jamal Mahajna
Pages: 1197-1204
Published online on: 01 June 2008

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Article

Synergistic apoptotic effects of taurolidine and TRAIL on squamous carcinoma cells of the esophagus

Adrien Daigeler, Ansgar Michael Chromik, Anne Geisler, Daniel Bulut, Christoph Hilgert, Andreas Krieg, Ludger Klein-Hitpass, Marcus Lehnhardt, Waldemar Uhl, Ulrich Mittelkötter
Pages: 1205-1220
Published online on: 01 June 2008

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Article

Involvement of Smad3 phosphoisoform-mediated signaling in the development of colonic cancer in IL-10-deficient mice

Daisaku Hachimine, Kazushige Uchida, Masanori Asada, Akiyoshi Nishio, Seiji Kawamata, Go Sekimoto, Miki Murata, Hideo Yamagata, Katsunori Yoshida, Shigeo Mori, Yoshiya Tahashi, Koichi Matsuzaki, Kazuichi Okazaki
Pages: 1221-1226
Published online on: 01 June 2008

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Article

Epigenetic modification is involved in aberrant expression of class III β-tubulin, TUBB3, in ovarian cancer cells

Naoko Izutsu, Chihaya Maesawa, Masahiko Shibazaki, Hiroki Oikawa, Tadahiro Shoji, Toru Sugiyama, Tomoyuki Masuda
Pages: 1227-1235
Published online on: 01 June 2008

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Article

Overexpression of Merlin in B16F10 mouse melanoma cells reduces their metastatic activity: Role of the cell surface heparan sulfate glycosaminoglycans

Zoya Galcheva-Gargova, Natalia Zhidkova, Sara Geisler, Jennifer Ozug, Steve Wudyka, Nur Sibel Gunay, Yi Wei Qi, Zachary Shriver, Ganesh Venkataraman
Pages: 1237-1243
Published online on: 01 June 2008

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Article

Genetic construction, expression, and characterization of a single chain anti-CEA antibody fused to cytosine deaminase from yeast

Silvia Zamboni, Alessandra Mallano, Michela Flego, Alessandro Ascione, Maria Luisa Dupuis, Mara Gellini, Stefano Barca, Maurizio Cianfriglia
Pages: 1245-1251
Published online on: 01 June 2008

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Article

Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma

Yohei Sogabe, Hiromu Suzuki, Minoru Toyota, Kazuhiro Ogi, Takashi Imai, Masanori Nojima, Yasushi Sasaki, Hiroyoshi Hiratsuka, Takashi Tokino
Pages: 1253-1261
Published online on: 01 June 2008

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Article

Novel humanized anti-CD20 monoclonal antibodies with unique germline VH and VL gene recruitment and potent effector functions

Michio Nishida, Keisuke Teshigawara, Otsura Niwa, Sadakazu Usuda, Tetsuo Nakamura, Peter Ralph, Roland Newman, Eduardo A. Padlan
Pages: 1263-1274
Published online on: 01 June 2008

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Article

Planar scintimammography and SPECT in neoadjuvant chemo or hormonotherapy response evaluation in locally advanced primary breast cancer

Angela Spanu, Antonio Farris, Francesca Chessa, Daniela Sanna, Maria Pittalis, Alessandra Manca, Giuseppe Madeddu
Pages: 1275-1283
Published online on: 01 June 2008

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Article

DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis

Xiaoling Zhou, Drazen B. Zimonjic, Sang-Won Park, Xu-Yu Yang, Marian E. Durkin, Nicholas C. Popescu
Pages: 1285-1291
Published online on: 01 June 2008

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Article

Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells

Fortunata Iacopino, Raffaella Urbano, Grazia Graziani, Alessia Muzi, Pierluigi Navarra, Gigliola Sica
Pages: 1293-1303
Published online on: 01 June 2008

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Article

Mechanism of resistance to chemoradiation in p53 mutant human colon cancer

Junichiro Hiro, Yasuhiro Inoue, Yuji Toiyama, Chikao Miki, Masato Kusunoki
Pages: 1305-1310
Published online on: 01 June 2008

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Article

KR-31831, benzopyran derivative, inhibits VEGF-induced angiogenesis of HUVECs through suppressing KDR expression

Shi-Young Park, Eun-Hee Seo, Hyun Seok Song, Seung-Youn Jung, Young-Kyoung Lee, Kyu-Yang Yi, Sung-Eun Yoo, Yung-Jin Kim
Pages: 1311-1315
Published online on: 01 June 2008

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Article

IFN-γ down-regulates Hsp27 and enhances hyperthermia-induced tumor cell death in vitro and tumor suppression in vivo

Mariko Oba, Shuichiro Yano, Tsuyoshi Shuto, Mary Ann Suico, Ayaka Eguma, Hirofumi Kai
Pages: 1317-1324
Published online on: 01 June 2008

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Article

2-Chloro-2'-deoxyadenosine-induced apoptosis in T leukemia cells is mediated via a caspase-3-dependent mitochondrial feedback amplification loop

David M. Conrad, Matthew R.J. Robichaud, Jamie S. Mader, Robert T.M. Boudreau, Angela M. Richardson, Carman A. Giacomantonio, David W. Hoskin
Pages: 1325-1333
Published online on: 01 June 2008

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Article

Down-regulation of Notch-1 expression decreases PU.1-mediated myeloid differentiation signaling in acute myeloid leukemia

Po-Min Chen, Chueh-Chuan Yen, Wei-Shu Wang, Yu-Jen Lin, Chiau-Jun Chu, Tzeon-Jye Chiou, Jin-Hwang Liu, Muh-Hwa Yang
Pages: 1335-1341
Published online on: 01 June 2008

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Article

Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells

Kai Gao, William W. Lockwood, Jun Li, Wan Lam, Gang Li
Pages: 1343-1349
Published online on: 01 June 2008

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Regulatory T cells in lung adenocarcinoma: Mechanisms of immune escape, prognostic significance and therapeutic opportunities (Review)

Lijuan Wang, Chenjin Ruan
Article Number: 130
Published online on: 06 October 2026

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Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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