1.
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar
|
2.
|
Ceelen W, Van Nieuwenhove Y and Pattyn P:
Surgery and intracavitary chemotherapy for peritoneal
carcinomatosis from colorectal origin. Acta Gastroenterol Belg.
71:373–378. 2008.PubMed/NCBI
|
3.
|
Watson AJ: An overview of apoptosis and
the prevention of colorectal cancer. Crit Rev Oncol Hematol.
57:107–121. 2006. View Article : Google Scholar : PubMed/NCBI
|
4.
|
Huang WW, Ko SW, Tsai HY, et al:
Cantharidin induces G2/M phase arrest and apoptosis in human
colorectal cancer colo 205 cells through inhibition of CDK1
activity and caspase-dependent signaling pathways. Int J Oncol.
38:1067–1073. 2011.
|
5.
|
Sato S: Modulation of Akt kinase activity
by binding to Hsp90. Proc Natl Acad Sci USA. 97:10832–10837. 2000.
View Article : Google Scholar : PubMed/NCBI
|
6.
|
Sreedhar AS, Sti C and Csermely P:
Inhibition of Hsp90: a new strategy for inhibiting protein kinases.
Biochim Biophys Acta. 1697:233–242. 2004. View Article : Google Scholar : PubMed/NCBI
|
7.
|
Schmitt E, Gehrmann M, Brunet M, Multhoff
G and Garrido C: Intracellular and extracellular functions of heat
shock proteins: repercussions in cancer therapy. J Leukoc Biol.
81:15–27. 2007. View Article : Google Scholar : PubMed/NCBI
|
8.
|
Morrow CJ: Bub1 and aurora B cooperate to
maintain BubR1-mediated inhibition of APC/CCdc20. J Cell Sci.
118:3639–3652. 2005. View Article : Google Scholar : PubMed/NCBI
|
9.
|
Peters JM: The anaphase promoting
complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell
Biol. 7:644–656. 2006. View Article : Google Scholar : PubMed/NCBI
|
10.
|
Jordan MA and Wilson L: Microtubules as a
target for anti-cancer drugs. Nat Rev Cancer. 4:253–265. 2004.
View Article : Google Scholar
|
11.
|
Bhalla KN: Microtubule-targeted anticancer
agents and apoptosis. Oncogene. 22:9075–9086. 2003. View Article : Google Scholar : PubMed/NCBI
|
12.
|
Carvajal RD, Tse A and Schwartz GK: Aurora
kinases: new targets for cancer therapy. Clin Cancer Res.
12:6869–6875. 2006. View Article : Google Scholar : PubMed/NCBI
|
13.
|
Pérez Fidalgo J, Roda D, Roselló S,
Rodríguez-Braun E and Cervantes A: Aurora kinase inhibitors: a new
class of drugs targeting the regulatory mitotic system. Clin Transl
Oncol. 11:787–798. 2009.PubMed/NCBI
|
14.
|
Fu J, Bian M, Jiang Q and Zhang C: Roles
of aurora kinases in mitosis and tumorigenesis. Mol Cancer Res.
5:1–10. 2007. View Article : Google Scholar : PubMed/NCBI
|
15.
|
Keen N and Taylor S: Aurora-kinase
inhibitors as anticancer agents. Nat Rev Cancer. 4:927–936. 2004.
View Article : Google Scholar : PubMed/NCBI
|
16.
|
Carpinelli P, Ceruti R, Giorgini ML, et
al: PHA-739358, a potent inhibitor of Aurora kinases with a
selective target inhibition profile relevant to cancer. Mol Cancer
Ther. 6:3158–3168. 2007. View Article : Google Scholar : PubMed/NCBI
|
17.
|
Andrews PD: Aurora kinases: shining lights
on the therapeutic horizon? Oncogene. 24:5005–5015. 2005.
View Article : Google Scholar : PubMed/NCBI
|
18.
|
Ruchaud S, Carmena M and Earnshaw WC:
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell
Biol. 8:798–812. 2007. View Article : Google Scholar : PubMed/NCBI
|
19.
|
Monaco L: Inhibition of Aurora-B kinase
activity by poly(ADP-ribosyl)ation in response to DNA damage. Proc
Natl Acad Sci USA. 102:14244–14248. 2005. View Article : Google Scholar : PubMed/NCBI
|
20.
|
Yasui Y: Autophosphorylation of a newly
identified site of aurora-B is indispensable for cytokinesis. J
Biol Chem. 279:12997–13003. 2003. View Article : Google Scholar : PubMed/NCBI
|
21.
|
Ghobrial IM, Witzig TE and Adjei AA:
Targeting apoptosis pathways in cancer therapy. CA Cancer J Clin.
55:178–194. 2005. View Article : Google Scholar : PubMed/NCBI
|
22.
|
O’Brien MA and Kirby R: Apoptosis: a
review of pro-apoptotic and anti-apoptotic pathways and
dysregulation in disease. J Vet Emerg Crit Care. 18:572–585.
2008.
|
23.
|
Lawen A: Apoptosis? an introduction.
BioEssays. 25:888–896. 2003. View Article : Google Scholar
|
24.
|
Cai Y, Cai B, Cui CB, Zhang DY, Han B,
Wang YG and Wang MW: Apoptosis-inducing effect of carbazole
alkaloid (HY-1) in human erythroleukemia K562 cells. Zhonghua Zhong
Liu Za Zhi. 27:457–460. 2005.(In Chinese).
|
25.
|
Roy M: Mechanism of mahanine-induced
apoptosis in human leukemia cells (HL-60). Biochem Pharmacol.
67:41–51. 2004. View Article : Google Scholar : PubMed/NCBI
|
26.
|
Roy MK, Thalang VN, Trakoontivakorn G and
Nakahara K: Mahanine, a carbazole alkaloid from Micromelum
minutum, inhibits cell growth and induces apoptosis in U937
cells through a mitochondrial dependent pathway. Br J Pharmacol.
145:145–155. 2005.
|
27.
|
Nafisi S, Malekabady ZM and Khalilzadeh
MA: Interaction of β-carboline alkaloids with RNA. DNA Cell Biol.
29:753–761. 2010.
|
28.
|
Mosmann T: Rapid colorimetric assay for
cellular growth and survival: application to proliferation and
cytotoxicity assays. J Immunol Methods. 65:55–63. 1983. View Article : Google Scholar : PubMed/NCBI
|
29.
|
Chang YH, Hsu MH, Wang SH, et al: Design
and synthesis of
2-(3-benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one analogues as
potent antitumor agents that inhibit tubulin assembly. J Med Chem.
52:4883–4891. 2009.
|
30.
|
Zhai D, Jin C, Huang Z, Satterthwait AC
and Reed JC: Differential regulation of Bax and Bak by
anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. J Biol Chem.
283:9580–9586. 2008. View Article : Google Scholar : PubMed/NCBI
|
31.
|
Brunelle JK and Letai A: Control of
mitochondrial apoptosis by the Bcl-2 family. Cell Sci. 122:437–441.
2009. View Article : Google Scholar : PubMed/NCBI
|
32.
|
Tsai JY, Lin YC, Hsu MH, Kuo SC and Huang
LJ: Synthesis and cytotoxicity of 1,6,8,9-substituted α-carboline
derivatives. Kaohsiung J of Med Sci. 26:593–602. 2010.
|
33.
|
Tasi JY, Hung CM, Bai ST, et al: Induction
of apoptosis by HAC-Y6, a novel microtubule inhibitor, through
activation of the death receptor 4 signaling pathway in human
hepatocellular carcinoma cells. Oncol Rep. 24:1169–1178. 2010.
|
34.
|
Perez EA: Microtubule inhibitors:
differentiating tubulin-inhibiting agents based on mechanisms of
action, clinical activity, and resistance. Mol Cancer Ther.
8:2086–2095. 2009. View Article : Google Scholar
|
35.
|
Yang J, Chen G, Hsia T, et al: Diallyl
disulfide induces apoptosis in human colon cancer cell line (COLO
205) through the induction of reactive oxygen species, endoplasmic
reticulum stress, caspases casade and mitochondrial-dependent
pathways. Food Chem Toxicol. 47:171–179. 2009. View Article : Google Scholar
|
36.
|
Yang J, Ikezoe T, Nishioka C, et al:
AZD1152, a novel and selective aurora B kinase inhibitor, induces
growth arrest, apoptosis and sensitization for tubulin
depolymerizing agent or topoisomerase II inhibitor in human acute
leukemia cells in vitro and in vivo. Blood. 110:2034–2040. 2007.
View Article : Google Scholar
|
37.
|
Lowe SW and Lin AW: Apoptosis in cancer.
Carcinogenesis. 21:485–495. 2000. View Article : Google Scholar
|
38.
|
Green DR and Reed JC: Mitochondria and
apoptosis. Science. 281:1309–1312. 1998. View Article : Google Scholar : PubMed/NCBI
|
39.
|
Eberle J, Fecker LF, Forschner T, Ulrich
C, Rowert-Huber J and Stockfleth E: Apoptosis pathways as promising
targets for skin cancer therapy. Br J Dermatol. 156(Suppl 3):
18–24. 2007. View Article : Google Scholar
|
40.
|
Dlamini Z, Mbita Z and Zungu M: Genealogy,
expression, and molecular mechanisms in apoptosis. Pharmacol Ther.
101:1–15. 2004. View Article : Google Scholar
|
41.
|
Bagci EZ, Vodovotz Y, Billiar TR,
Ermentrout GB and Bahar I: Bistability in apoptosis: roles of Bax,
Bcl-2, and mitochondrial permeability transition pores. Biophys J.
90:1546–1559. 2006. View Article : Google Scholar : PubMed/NCBI
|
42.
|
Antonsson B, Conti F, Ciavatta A, et al:
Inhibition of Bax channel-forming activity by Bcl-2. Science.
277:370–372. 1997. View Article : Google Scholar : PubMed/NCBI
|
43.
|
Pratt WB and Toft DO: Regulation of
signaling protein function and trafficking by the hsp90/hsp70-based
chaperone machinery. Exp Biol Med (Maywood). 228:111–133.
2003.PubMed/NCBI
|
44.
|
Bai L, Xu S, Chen W, et al: Blocking
NF-kappaB and Akt by Hsp90 inhibition sensitizes Smac mimetic
compound 3-induced extrinsic apoptosis pathway and results in
synergistic cancer cell death. Apoptosis. 16:45–54. 2011.
View Article : Google Scholar : PubMed/NCBI
|