Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review)

  • Authors:
    • Sukant Garg
    • Sunil C. Kaul
    • Renu Wadhwa
  • View Affiliations

  • Published online on: November 10, 2017     https://doi.org/10.3892/ijo.2017.4203
  • Pages:19-37
Metrics: HTML 0 views | PDF 0 views
0

Abstract

Cancer is one of the most important healthcare matters, with the worst prognosis but the best possibilities for scientific development. It is likely to increase in the future and cause global havoc designating it as an epidemic. Cancer development requires urgent intervention. Past few decades have witnessed extensive research to challenge carcinogenesis. Treatment involving synthetic discipline is often associated with severe adverse effects, or even worsened prognosis. Accordingly, newer economic and patient friendly molecules are warranted. Many natural substances have proved their potential so far. Cucurbitacin B against cancer and other diseases has achieved towering popularity among the researchers around the world, as detailed in the below sections with summarized tables. In line with the fascinating role of cucurbitacin B against various types of cancers, through various molecular signaling pathways, it is justifiable to propose cucurbitacin B as a mainline chemotherapy before the onset and after the diagnosis of cancer.

Related Articles

Journal Cover

January 2018
Volume 52 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

2016 Impact Factor: 3.079
Ranked #33/217 Oncology
(total number of cites)

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
APA
Garg, S., Kaul, S.C., & Wadhwa, R. (2018). Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review). International Journal of Oncology, 52, 19-37. https://doi.org/10.3892/ijo.2017.4203
MLA
Garg, S., Kaul, S. C., Wadhwa, R."Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review)". International Journal of Oncology 52.1 (2018): 19-37.
Chicago
Garg, S., Kaul, S. C., Wadhwa, R."Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review)". International Journal of Oncology 52, no. 1 (2018): 19-37. https://doi.org/10.3892/ijo.2017.4203