1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
2
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Moch H, Cubilla AL, Humphrey PA, Reuter VE
and Ulbright TM: The 2016 WHO Classification of Tumours of the
Urinary System and Male Genital Organs-Part A: Renal, penile, and
testicular Tumours. Eur Urol. 70:93–105. 2016. View Article : Google Scholar : PubMed/NCBI
|
4
|
Novara G, Ficarra V, Antonelli A, Artibani
W, Bertini R, Carini M, Cosciani Cunico S, Imbimbo C, Longo N,
Martignoni G, et al: SATURN Project-LUNA Foundation: Validation of
the 2009 TNM version in a large multi-institutional cohort of
patients treated for renal cell carcinoma: Are further improvements
needed? Eur Urol. 58:588–595. 2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Gong J, Maia MC, Dizman N, Govindarajan A
and Pal SK: Metastasis in renal cell carcinoma: Biology and
implications for therapy. Asian J Urol. 3:286–292. 2016. View Article : Google Scholar : PubMed/NCBI
|
6
|
Pichler M, Hutterer GC, Chromecki TF,
Jesche J, Kampel-Kettner K, Rehak P, Pummer K and Zigeuner R:
External validation of the Leibovich prognosis score for
nonmetastatic clear cell renal cell carcinoma at a single European
center applying routine pathology. J Urol. 186:1773–1777. 2011.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Albiges L, Fay AP, Xie W, Krajewski K,
McDermott DF, Heng DY, Dariane C, DeVelasco G, Lester R, Escudier
B, et al: Efficacy of targeted therapies after PD-1/PD-L1 blockade
in metastatic renal cell carcinoma. Eur J Cancer. 51:2580–2586.
2015. View Article : Google Scholar : PubMed/NCBI
|
8
|
Oudard S and Vano Y: The role of
rechallenge with targeted therapies in metastatic renal-cell
carcinoma. Curr Opin Urol. 25:402–410. 2015. View Article : Google Scholar : PubMed/NCBI
|
9
|
Zanardi E, Verzoni E, Grassi P, Necchi A,
Giannatempo P, Raggi D, De Braud F and Procopio G: Clinical
experience with temsirolimus in the treatment of advanced renal
cell carcinoma. Ther Adv Urol. 7:152–161. 2015. View Article : Google Scholar : PubMed/NCBI
|
10
|
Bickel PE, Tansey JT and Welte MA: PAT
proteins, an ancient family of lipid droplet proteins that regulate
cellular lipid stores. Biochim Biophys Acta. 1791:419–440. 2009.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Kimmel AR, Brasaemle DL, McAndrews-Hill M,
Sztalryd C and Londos C: Adoption of PERILIPIN as a unifying
nomenclature for the mammalian PAT-family of intracellular lipid
storage droplet proteins. J Lipid Res. 51:468–471. 2010. View Article : Google Scholar :
|
12
|
Brasaemle DL: Thematic review series:
adipocyte biology. The perilipin family of structural lipid droplet
proteins: stabilization of lipid droplets and control of lipolysis.
J Lipid Res. 48:2547–2559. 2007. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ducharme NA and Bickel PE: Lipid droplets
in lipogenesis and lipolysis. Endocrinology. 149:942–949. 2008.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Londos C, Sztalryd C, Tansey JT and Kimmel
AR: Role of PAT proteins in lipid metabolism. Biochimie. 87:45–49.
2005. View Article : Google Scholar : PubMed/NCBI
|
15
|
Lu X, Gruia-Gray J, Copeland NG, Gilbert
DJ, Jenkins NA, Londos C and Kimmel AR: The murine perilipin gene:
The lipid droplet-associated perilipins derive from
tissue-specific, mRNA splice variants and define a gene family of
ancient origin. Mamm Genome. 12:741–749. 2001. View Article : Google Scholar : PubMed/NCBI
|
16
|
Miura S, Gan JW, Brzostowski J, Parisi MJ,
Schultz CJ, Londos C, Oliver B and Kimmel AR: Functional
conservation for lipid storage droplet association among Perilipin,
ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and
Dictyostelium. J Biol Chem. 277:32253–32257. 2002. View Article : Google Scholar : PubMed/NCBI
|
17
|
Thiele C and Spandl J: Cell biology of
lipid droplets. Curr Opin Cell Biol. 20:378–385. 2008. View Article : Google Scholar : PubMed/NCBI
|
18
|
Zehmer JK, Huang Y, Peng G, Pu J, Anderson
RG and Liu P: A role for lipid droplets in inter-membrane lipid
traffic. Proteomics. 9:914–921. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Walther TC and Farese RV Jr: Lipid
droplets and cellular lipid metabolism. Annu Rev Biochem.
81:687–714. 2012. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhou C, Wang M, Zhou L, Zhang Y, Liu W,
Qin W, He R, Lu Y, Wang Y, Chen XZ, et al: Prognostic significance
of PLIN1 expression in human breast cancer. Oncotarget.
7:54488–54502. 2016.PubMed/NCBI
|
21
|
Szigeti A, Minik O, Hocsak E, Pozsgai E,
Boronkai A, Farkas R, Balint A, Bodis J, Sumegi B and Bellyei S:
Preliminary study of TIP47 as a possible new biomarker of cervical
dysplasia and invasive carcinoma. Anticancer Res. 29:717–724.
2009.PubMed/NCBI
|
22
|
Jiang HP, Harris SE and Serrero G:
Molecular cloning of a differentiation-related mRNA in the
adipogenic cell line 1246. Cell Growth Differ. 3:21–30.
1992.PubMed/NCBI
|
23
|
Jiang HP and Serrero G: Isolation and
characterization of a full-length cDNA coding for an adipose
differentiation-related protein. Proc Natl Acad Sci USA.
89:7856–7860. 1992. View Article : Google Scholar : PubMed/NCBI
|
24
|
Chong BM, Reigan P, Mayle-Combs KD,
Orlicky DJ and McManaman JL: Determinants of adipophilin function
in milk lipid formation and secretion. Trends Endocrinol Metab.
22:211–217. 2011. View Article : Google Scholar : PubMed/NCBI
|
25
|
Brasaemle DL, Barber T, Wolins NE, Serrero
G, Blanchette-Mackie EJ and Londos C: Adipose
differentiation-related protein is an ubiquitously expressed lipid
storage droplet-associated protein. J Lipid Res. 38:2249–2263.
1997.PubMed/NCBI
|
26
|
Phillips SA, Choe CC, Ciaraldi TP,
Greenberg AS, Kong AP, Baxi SC, Christiansen L, Mudaliar SR and
Henry RR: Adipocyte differentiation-related protein in human
skeletal muscle: Relationship to insulin sensitivity. Obes Res.
13:1321–1329. 2005. View Article : Google Scholar : PubMed/NCBI
|
27
|
Heid HW, Moll R, Schwetlick I, Rackwitz HR
and Keenan TW: Adipophilin is a specific marker of lipid
accumulation in diverse cell types and diseases. Cell Tissue Res.
294:309–321. 1998. View Article : Google Scholar : PubMed/NCBI
|
28
|
Zhang XD, Li W, Zhang N, Hou YL, Niu ZQ,
Zhong YJ, Zhang YP and Yang SY: Identification of adipophilin as a
potential diagnostic tumor marker for lung adenocarcinoma. Int J
Clin Exp Med. 7:1190–1196. 2014.PubMed/NCBI
|
29
|
Matsubara J, Honda K, Ono M, Sekine S,
Tanaka Y, Kobayashi M, Jung G, Sakuma T, Nakamori S, Sata N, et al:
Identification of adipophilin as a potential plasma biomarker for
colorectal cancer using label-free quantitative mass spectrometry
and protein microarray. Cancer Epidemiol Biomarkers Prev.
20:2195–2203. 2011. View Article : Google Scholar : PubMed/NCBI
|
30
|
Mentrikoski MJ, Wendroth SM and Wick MR:
Immunohistochemical distinction of renal cell carcinoma from other
carcinomas with clear-cell histomorphology: Utility of CD10 and
CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin. Appl
Immunohistochem Mol Morphol. 22:635–641. 2014. View Article : Google Scholar : PubMed/NCBI
|
31
|
Straub BK, Herpel E, Singer S, Zimbelmann
R, Breuhahn K, Macher-Goeppinger S, Warth A, Lehmann-Koch J,
Longerich T, Heid H, et al: Lipid droplet-associated PAT-proteins
show frequent and differential expression in neoplastic
steatogenesis. Mod Pathol. 23:480–492. 2010. View Article : Google Scholar : PubMed/NCBI
|
32
|
Yao M, Huang Y, Shioi K, Hattori K,
Murakami T, Nakaigawa N, Kishida T, Nagashima Y and Kubota Y:
Expression of adipose differentiation-related protein: A predictor
of cancer-specific survival in clear cell renal carcinoma. Clin
Cancer Res. 13:152–160. 2007. View Article : Google Scholar : PubMed/NCBI
|
33
|
Tolkach Y, Lüders C, Meller S, Jung K,
Stephan C and Kristiansen G: Adipophilin as prognostic biomarker in
clear cell renal cell carcinoma. Oncotarget. 8:28672–28682. 2017.
View Article : Google Scholar : PubMed/NCBI
|
34
|
Qiu B, Ackerman D, Sanchez DJ, Li B,
Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B
and Simon MC: HIF2α-dependent lipid storage promotes endoplasmic
reticulum homeostasis in clear-cell renal cell carcinoma. Cancer
Discov. 5:652–667. 2015. View Article : Google Scholar : PubMed/NCBI
|
35
|
Ruan H, Li X, Yang H, Song Z, Tong J, Cao
Q, Wang K, Xiao W, Xiao H, Chen X, et al: Enhanced expression of
caveolin-1 possesses diagnostic and prognostic value and promotes
cell migration, invasion and sunitinib resistance in the clear cell
renal cell carcinoma. Exp Cell Res. 358:269–278. 2017. View Article : Google Scholar : PubMed/NCBI
|
36
|
Liu R, Qin X, Ji C, Zeng W, Yang Y and Tan
W: Pygopus 2 promotes kidney cancer OS-RC-2 cells proliferation and
inva-sionin vitroandin vivo. Asian J Urol. 2:151–157. 2015.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Cline MS, Craft B, Swatloski T, Goldman M,
Ma S, Haussler D and Zhu J: Exploring TCGA pan-cancer data at the
UCSC cancer genomics browser. Sci Rep. 3:26522013. View Article : Google Scholar : PubMed/NCBI
|
38
|
Subramanian A, Tamayo P, Mootha VK,
Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub
TR, Lander ES, et al: Gene set enrichment analysis: A
knowledge-based approach for interpreting genome-wide expression
profiles. Proc Natl Acad Sci USA. 102:15545–15550. 2005. View Article : Google Scholar : PubMed/NCBI
|
39
|
Targett-Adams P, Chambers D, Gledhill S,
Hope RG, Coy JF, Girod A and McLauchlan J: Live cell analysis and
targeting of the lipid droplet-binding adipocyte
differentiation-related protein. J Biol Chem. 278:15998–16007.
2003. View Article : Google Scholar : PubMed/NCBI
|
40
|
Morrissey JJ, Mobley J, Figenshau RS,
Vetter J, Bhayani S and Kharasch ED: Urine aquaporin 1 and
perilipin 2 differentiate renal carcinomas from other imaged renal
masses and bladder and prostate cancer. Mayo Clin Proc. 90:35–42.
2015. View Article : Google Scholar : PubMed/NCBI
|
41
|
Ambrosio MR, Piccaluga PP, Ponzoni M,
Rocca BJ, Malagnino V, Onorati M, De Falco G, Calbi V, Ogwang M,
Naresh KN, et al: The alteration of lipid metabolism in Burkitt
lymphoma identifies a novel marker: Adipophilin. PLoS One.
7:e443152012. View Article : Google Scholar : PubMed/NCBI
|
42
|
Fujimoto M, Matsuzaki I, Yamamoto Y,
Yoshizawa A, Warigaya K, Iwahashi Y, Kojima F, Furukawa F and
Murata SI: Adipophilin expression in cutaneous malignant melanoma.
J Cutan Pathol. 44:228–236. 2017. View Article : Google Scholar
|
43
|
Lucenay KS, Doostan I, Karakas C, Bui T,
Ding Z, Mills GB, Hunt KK and Keyomarsi K: Cyclin E associates with
the lipogenic enzyme ATP-citrate lyase to enable malignant growth
of breast cancer cells. Cancer Res. 76:2406–2418. 2016. View Article : Google Scholar : PubMed/NCBI
|
44
|
Yao M, Tabuchi H, Nagashima Y, Baba M,
Nakaigawa N, Ishiguro H, Hamada K, Inayama Y, Kishida T, Hattori K,
et al: Gene expression analysis of renal carcinoma: Adipose
differentiation-related protein as a potential diagnostic and
prognostic biomarker for clear-cell renal carcinoma. J Pathol.
205:377–387. 2005. View Article : Google Scholar : PubMed/NCBI
|
45
|
Targett-Adams P, McElwee MJ, Ehrenborg E,
Gustafsson MC, Palmer CN and McLauchlan J: A PPAR response element
regulates transcription of the gene for human adipose
differentiation-related protein. Biochim Biophys Acta. 1728:95–104.
2005. View Article : Google Scholar : PubMed/NCBI
|