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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2018 Volume 53 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Roles of STAT3 in leukemia (Review)

Yin Shi, Zhen Zhang, Xintao Qu, Xiaoxiao Zhu, Lin Zhao, Ran Wei, Qiang Guo, Linlin Sun, Xunqiang Yin, Yunhong Zhang, Xia Li
Pages: 7-20
Published online on: 30 April 2018

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Article Open Access

Long non-coding RNA HOXD-AS1 promotes tumor progression and predicts poor prognosis in colorectal cancer

Xiang Li, Xinhan Zhao, Binhui Yang, Yuqing Li, Tao Liu, Linyuan Pang, Zhigang Fan, Wu Ma, Zhongqiu Liu, Zeng Li
Pages: 21-32
Published online on: 09 May 2018

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Article Open Access

Survivin knockdown induces senescence in TTF‑1-expressing, KRAS-mutant lung adenocarcinomas

Toshiyuki Sumi, Sachie Hirai, Miki Yamaguchi, Yusuke Tanaka, Makoto Tada, Gen Yamada, Tadashi Hasegawa, Yohei Miyagi, Toshiro Niki, Atsushi Watanabe, Hiroki Takahashi, Yuji Sakuma
Pages: 33-46
Published online on: 11 April 2018

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Article Open Access

Oct4 suppresses IR‑induced premature senescence in breast cancer cells through STAT3- and NF‑κB-mediated IL‑24 production

Jeong-Yub Kim, Jeong-Chul Kim, Ji-Yun Lee, Myung-Jin Park
Pages: 47-58
Published online on: 02 May 2018

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Article Open Access

MORC2, a novel oncogene, is upregulated in liver cancer and contributes to proliferation, metastasis and chemoresistance

Zhihong Pan, Qianshan Ding, Qian Guo, Yong Guo, Lianlian Wu, Lu Wu, Meng Tang, Honggang Yu, Fuxiang Zhou
Pages: 59-72
Published online on: 27 March 2018

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Article Open Access

Upregulation of HOXA1 promotes tumorigenesis and development of non‑small cell lung cancer: A comprehensive investigation based on reverse transcription-quantitative polymerase chain reaction and bioinformatics analysis

Yu Zhang, Xiao-Jiao Li, Rong-Quan He, Xiao Wang, Tong-Tong Zhang, Yuan Qin, Rui Zhang, Yun Deng, Han-Lin Wang, Dian-Zhong Luo, Gang Chen
Pages: 73-86
Published online on: 16 April 2018

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Article Open Access

Differences between carcinoma of the cecum and ascending colon: Evidence based on clinical and embryological data

Xin Xie, Zhangjian Zhou, Yongchun Song, Wei Wang, Chengxue Dang, Hao Zhang
Pages: 87-98
Published online on: 12 April 2018

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Article Open Access

HepaCAM inhibits the malignant behavior of castration-resistant prostate cancer cells by downregulating Notch signaling and PF-3084014 (a γ-secretase inhibitor) partly reverses the resistance of refractory prostate cancer to docetaxel and enzalutamide in vitro

Zhongbo Du, Luo Li, Wei Sun, Xiao Wang, Yao Zhang, Zhixiong Chen, Mengjuan Yuan, Zhen Quan, Nanjing Liu, Yanni Hao, Ting Li, Jinhua Wang, Chunli Luo, Xiaohou Wu
Pages: 99-112
Published online on: 12 April 2018

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Article Open Access

Antitumoral effect of Ocoxin, a natural compound-containing nutritional supplement, in small cell lung cancer

Elena Díaz-Rodríguez, Eduardo Sanz, Atanasio Pandiella
Pages: 113-123
Published online on: 16 April 2018

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Article Open Access

miR-125a induces apoptosis, metabolism disorder and migrationimpairment in pancreatic cancer cells by targeting Mfn2-related mitochondrial fission

Lichao Pan, Lin Zhou, Weijia Yin, Jia Bai, Rong Liu
Pages: 124-136
Published online on: 26 April 2018

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Article Open Access

Overexpression of PLIN2 is a prognostic marker and attenuates tumor progression in clear cell renal cell carcinoma

Qi Cao, Hailong Ruan, Keshan Wang, Zhengshuai Song, Lin Bao, Tianbo Xu, Haibing Xiao, Cheng Wang, Gong Cheng, Junwei Tong, Xiangui Meng, Di Liu, Hongmei Yang, Ke Chen, Xiaoping Zhang
Pages: 137-147
Published online on: 26 April 2018

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Article Open Access

The upregulation of TMPRSS4, partly ascribed to the downregulation of miR‑125a‑5p, promotes the growth of human lung adenocarcinoma via the NF‑κB signaling pathway

Xiaoxi Fan, Yicheng Liang, Yang Liu, Yunpeng Bai, Chunlu Yang, Shun Xu
Pages: 148-158
Published online on: 07 May 2018

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Article

NRP1 knockdown promotes the migration and invasion of human neuroblastoma-derived SK‑N‑AS cells via the activation of β1 integrin expression

Yoshiaki Ishizuka, Tsugumichi Koshinaga, Takayuki Hirano, Eri Nagasaki‑Maeoka, Yosuke Watanabe, Reina Hoshi, Shinsuke Yoshizawa, Kiminobu Sugito, Hiroyuki Kawashima, Shota Uekusa, Noboru Fukuda, Masayoshi Soma, Kyoko Fujiwara
Pages: 159-166
Published online on: 07 May 2018

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Article

C-terminal binding protein‑2 mediates cisplatin chemoresistance in esophageal cancer cells via the inhibition of apoptosis

Hui Shi, Yinting Mao, Qianqian Ju, Yingcheng Wu, Wen Bai, Peiwen Wang, Yudong Zhang, Maorong Jiang
Pages: 167-176
Published online on: 12 April 2018

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Article

Genistein reduces the activation of AKT and EGFR, and the production of IL6 in cholangiocarcinoma cells involving estrogen and estrogen receptors

Pariyada Tanjak, Apinya Thiantanawat, Piyajit Watcharasit, Jutamaad Satayavivad
Pages: 177-188
Published online on: 24 April 2018

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Article

Association between SOX9 and CA9 in glioma, and its effects on chemosensitivity to TMZ

Xiaoshan Xu, Zhen Wang, Nan Liu, Yingduan Cheng, Weilin Jin, Pengxing Zhang, Xin Wang, Hongwei Yang, Hui Liu, Yongsheng Zhang, Yanyang Tu
Pages: 189-202
Published online on: 26 April 2018

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Article

Ubiquitin ligase CHIP functions as an oncogene and activates the AKT signaling pathway in prostate cancer

Li Cheng, Jin Zang, Han-Jue Dai, Feng Li, Feng Guo
Pages: 203-214
Published online on: 24 April 2018

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Article

Hypoxia-induced autophagy promotes gemcitabine resistance in human bladder cancer cells through hypoxia-inducible factor 1α activation

Xiaoyu Yang, Hubin Yin, Yunzhi Zhang, Xinyuan Li, Hang Tong, Yizhou Zeng, Quan Wang, Weiyang He
Pages: 215-224
Published online on: 24 April 2018

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Article

Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway

Li Li, Yujuan Zhong, Zuheng Ma, Chengfang Yang, Hanning Wei, Li Chen, Chen Li, Dan Wu, Ming Zhi Rong, Yongwen Li
Pages: 225-236
Published online on: 26 April 2018

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Article

Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma

Naoto Iwai, Kohichiroh Yasui, Akira Tomie, Yasuyuki Gen, Kei Terasaki, Tomoko Kitaichi, Tomohiro Soda, Nobuhisa Yamada, Osamu Dohi, Yuya Seko, Atsushi Umemura, Taichiro Nishikawa, Kanji Yamaguchi, Michihisa Moriguchi, Hideyuki Konishi, Yuji Naito, Yoshito Itoh
Pages: 237-245
Published online on: 12 April 2018

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Article

Circular RNA circCDK13 suppresses cell proliferation, migration and invasion by modulating the JAK/STAT and PI3K/AKT pathways in liver cancer

Qu Lin, Yun-Biao Ling, Jun-Wei Chen, Chu-Ren Zhou, Jie Chen, Xing Li, Ming-Sheng Huang
Pages: 246-256
Published online on: 12 April 2018

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Article

miR‑145 inhibits human non‑small-cell lung cancer growth by dual-targeting RIOK2 and NOB1

Kun Liu, Honglin Chen, Qingsheng You, Qing Ye, Fei Wang, Shuo Wang, Shuanglong Zhang, Kangjun Yu, Weinan Li, Mingming Gu
Pages: 257-265
Published online on: 03 May 2018

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Article

Inhibition of CD9 expression reduces the metastatic capacity of human hepatocellular carcinoma cell line MHCC97-H

Qing Lin, Shifang Peng, Yixuan Yang
Pages: 266-274
Published online on: 26 April 2018

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Article

Production of an anti-TM4SF5 monoclonal antibody and its application in the detection of TM4SF5 as a possible marker of a poor prognosis in colorectal cancer

Byoung Kwon Park, Jae-Young Park, Te Ha Kim, Dongbum Kim, Guang Wu, Avishekh Gautam, Sony Maharjan, Su In Lee, Younghee Lee, Hyung-Joo Kwon, Kyung Chan Choi
Pages: 275-285
Published online on: 26 April 2018

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Article

Role of the overexpression of TRAF4 in predicting the prognosis of intrahepatic cholangiocarcinoma

Qiang Kang, Hao Zou, Lei Zhou, Li-Xin Liu, Jia-Bin Cai, Nan Xie, Wei-Hao Li, Chao Zhang, Wan-Hong Shi, Lian-Min Wang, Wei-Han Zhang, Hong Zhu, Shu-Fen Wang, Xiao-Wen Zhang
Pages: 286-296
Published online on: 26 April 2018

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Article

SPAG6 silencing induces apoptosis in the myelodysplastic syndrome cell line SKM‑1 via the PTEN/PI3K/AKT signaling pathway in vitro and in vivo

Jiaxiu Yin, Xinxin Li, Zaili Zhang, Xiaohua Luo, Li Wang, Lin Liu
Pages: 297-306
Published online on: 02 May 2018

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Article

12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18

Adryan Fristiohady, Daniela Milovanovic, Sigurd Krieger, Nicole Huttary, Chi Huu Nguyen, Jose Basilio, Walter Jäger, Rainer De Martin, Georg Krupitza
Pages: 307-316
Published online on: 26 April 2018

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Article

Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells Corrigendum in /10.3892/ijo.2020.5113

Mingjing Shen, Yongbing Chen, Lijun Xu, Rongying Zhu, Xiang Xue, Ying Tsai, Peter C. Keng, Soo Ok Lee, Yuhchyau Chen
Pages: 317-328
Published online on: 04 May 2018

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Article

MicroRNA-18a inhibits cell growth and induces apoptosis in osteosarcoma by targeting MED27

Jing Ding, Lin Sha, Pinquan Shen, Man Huang, Qixun Cai, Jiyu Li
Pages: 329-338
Published online on: 16 April 2018

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Article

Stat3/Oct-4/c-Myc signal circuit for regulating stemness-mediated doxorubicin resistance of triple-negative breast cancer cells and inhibitory effects of WP1066

Cong-Cong Cheng, Li-Hong Shi, Xue-Jian Wang, Shu-Xiao Wang, Xiao-Qing Wan, Shu-Rong Liu, Yi-Fei Wang, Zhong Lu, Li-Hua Wang, Yi Ding
Pages: 339-348
Published online on: 08 May 2018

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Article

Inhibition of interleukin 8/C‑X-C chemokine receptor 1,/2 signaling reduces malignant features in human pancreatic cancer cells

Shengling Fu, Xiang Chen, Huey-Jen Lin, Jiayuh Lin
Pages: 349-357
Published online on: 30 April 2018

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Article

High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways

Yaling Qi, Wenjie Zhao, Mengsen Li, Mingliang Shao, Jingtao Wang, Hongyu Sui, Haibo Yu, Wenwu Shao, Shiliang Gui, Jing Li, Xiuyue Jia, Dali Jiang, Yue Li, Pengxia Zhang, Shuqiu Wang, Weiqun Wang
Pages: 358-370
Published online on: 30 April 2018

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Article

USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT/Skp2 pathway

Yawen Tan, Guanglin Zhou, Xianming Wang, Weicai Chen, Haidong Gao
Pages: 371-383
Published online on: 30 April 2018

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Article

Knockdown of SNHG15 suppresses renal cell carcinoma proliferation and EMT by regulating the NF-κB signaling pathway Corrigendum in /10.3892/ijo.2022.5326

Yang Du, Chuize Kong, Yuyan Zhu, Meng Yu, Zeliang Li, Jianbin Bi, Zhenhua Li, Xiankui Liu, Zhe Zhang, Xiuyue Yu
Pages: 384-394
Published online on: 04 May 2018

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Article

Oncogenic IL7R is downregulated by histone deacetylase inhibitor in esophageal squamous cell carcinoma via modulation of acetylated FOXO1

Myoung Jun Kim, Sung Kyung Choi, Seong Hwi Hong, Jung Woo Eun, Suk Woo Nam, Jeung-Whan Han, Jueng Soo You
Pages: 395-403
Published online on: 02 May 2018

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Article

PGC1α promotes cisplatin resistance in human ovarian carcinoma cells through upregulation of mitochondrial biogenesis

Luyan Shen, Boyang Sun, Jiyao Sheng, Sihang Yu, Yanqing Li, Huadan Xu, Jing Su, Liankun Sun
Pages: 404-416
Published online on: 09 May 2018

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Article

Genome-wide analysis of lncRNAs in 3'-untranslated regions: CR933609 acts as a decoy to protect the INO80D gene

Chun‑Chi Chang, Ting-Yuan Liu, Ya‑Ting Lee, Yu-Chia Chen, Kun‑Tu Yeh, Chien‑Chin Lee, Ya‑Ling Chen, Pei-Chin Lin, Ya‑Sian Chang, Wen‑Ling Chan, Ta‑Chih Liu, Jan‑Gowth Chang
Pages: 417-433
Published online on: 08 May 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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