|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
Statistics, 2017. CA Cancer J Clin. 67:7–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Litwin MS and Tan HJ: The diagnosis and
treatment of prostate cancer: A review. JAMA. 317:2532–2542. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Paul I and Ghosh MK: The E3 ligase CHIP:
Insights into its structure and regulation. BioMed Res Int.
2014:9181832014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Murata S, Minami Y, Minami M, Chiba T and
Tanaka K: CHIP is a chaperone-dependent E3 ligase that
ubiquitylates unfolded protein. EMBO Rep. 2:1133–1138. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Paul I and Ghosh MK: A CHIPotle in
physiology and disease. Int J Biochem Cell Biol. 58:37–52. 2015.
View Article : Google Scholar
|
|
7
|
McDonough H and Patterson C: CHIP: A link
between the chaperone and proteasome systems. Cell Stress
Chaperones. 8:303–308. 2003. View Article : Google Scholar
|
|
8
|
Connell P, Ballinger CA, Jiang J, Wu Y,
Thompson LJ, Höhfeld J and Patterson C: The co-chaperone CHIP
regulates protein triage decisions mediated by heat-shock proteins.
Nat Cell Biol. 3:93–96. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Shang Y, He J, Wang Y, Feng Q, Zhang Y,
Guo J, Li J, Li S, Wang Y, Yan G, et al: CHIP/Stub1 regulates the
Warburg effect by promoting degradation of PKM2 in ovarian
carcinoma. Oncogene. 36:4191–4200. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yonezawa T, Takahashi H, Shikata S, Liu X,
Tamura M, Asada S, Fukushima T, Fukuyama T, Tanaka Y, Sawasaki T,
et al: The ubiquitin ligase STUB1 regulates stability and activity
of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 292:12528–12541. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
1Liu F, Zhou J, Zhou P, Chen W and Guo F:
The ubiquitin ligase CHIP inactivates NF-κB signaling and impairs
the ability of migration and invasion in gastric cancer cells. Int
J Oncol. 46:2096–2106. 2015. View Article : Google Scholar
|
|
12
|
Zhang L, Liu L, He X, Shen Y, Liu X, Wei
J, Yu F and Tian J: CHIP promotes thyroid cancer proliferation via
activation of the MAPK and AKT pathways. Biochem Biophys Res
Commun. 477:356–362. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Jin Y, Zhou L, Liang ZY, Jin KM, Zhou WX
and Xing BC: Clinicopathologic and prognostic significance of
carboxyl terminus of Hsp70-interacting protein in HBV-related
hepatocellular carcinoma. Asian Pac J Cancer Prev. 16:3709–3713.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−ΔΔC(T)) Method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
15
|
Tang X, Zhang L and Wei W: Roles of TRAFs
in NF-κB signaling pathways mediated by BAFF. Immunol Lett.
196:113–118. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mali AV, Joshi AA, Hegde MV and Kadam ShS:
Enterolactone suppresses proliferation, migration and metastasis of
MDA-MB-231 breast cancer cells through inhibition of uPA induced
plasmin activation and MMPs-mediated ECM remodeling. Asian Pac J
Cancer Prev. 18:905–915. 2017.PubMed/NCBI
|
|
17
|
Kurozumi A, Goto Y, Matsushita R, Fukumoto
I, Kato M, Nishikawa R, Sakamoto S, Enokida H, Nakagawa M, Ichikawa
T, et al: Tumor-suppressive microRNA-223 inhibits cancer cell
migration and invasion by targeting ITGA3/ITGB1 signaling in
prostate cancer. Cancer Sci. 107:84–94. 2016. View Article : Google Scholar
|
|
18
|
Grant CM and Kyprianou N: Epithelial
mesenchymal transition (EMT) in prostate growth and tumor
progression. Transl Androl Urol. 2:202–211. 2013.
|
|
19
|
Nakazawa M and Kyprianou N:
Epithelial-mesenchymal-transition regulators in prostate cancer:
Androgens and beyond. J Steroid Biochem Mol Biol. 166:84–90. 2017.
View Article : Google Scholar
|
|
20
|
Zhang T, Zhao G, Yang C, Dong P, Watari H,
Zeng L, Pfeffer LM and Yue J: Lentiviral vector mediated-ASAP1
expression promotes epithelial to mesenchymal transition in ovarian
cancer cells. Oncol Lett. 15:4432–4438. 2018.PubMed/NCBI
|
|
21
|
Chaudhari PR, Charles SE, D'Souza ZC and
Vaidya MM: Hemidesmosomal linker proteins regulate cell motility,
invasion and tumorigenicity in oral squamous cell carcinoma derived
cells. Exp Cell Res. 360:125–137. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Nassour M, Idoux-Gillet Y, Selmi A, Côme
C, Faraldo ML, Deugnier MA and Savagner P: Slug controls
stem/progenitor cell growth dynamics during mammary gland
morphogenesis. PLoS One. 7:e534982012. View Article : Google Scholar
|
|
23
|
Wu F, Zhu J, Mao Y, Li X, Hu B and Zhang
D: Associations between the epithelial-mesenchymal transition
phenotypes of circulating tumor cells and the clinicopathological
features of patients with colorectal cancer. Dis Markers.
2017:94745322017. View Article : Google Scholar
|
|
24
|
Szostak MJ and Kyprianou N:
Radiation-induced apoptosis: Predictive and therapeutic
significance in radiotherapy of prostate cancer (Review). Oncol
Rep. 7:699–706. 2000.PubMed/NCBI
|
|
25
|
Motta M, Dondi D, Moretti RM, Montagnani
Marelli M, Pimpinelli F, Maggi R and Limonta P: Role of growth
factors, steroid and peptide hormones in the regulation of human
prostatic tumor growth. J Steroid Biochem Mol Biol. 56:107–111.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang Y, Ren F, Wang Y, Feng Y, Wang D, Jia
B, Qiu Y, Wang S, Yu J, Sung JJ, et al: CHIP/Stub1 functions as a
tumor suppressor and represses NF-κB-mediated signaling in
colorectal cancer. Carcinogenesis. 35:983–991. 2014. View Article : Google Scholar
|
|
27
|
Wang S, Wu X, Zhang J, Chen Y, Xu J, Xia
X, He S, Qiang F, Li A, Shu Y, et al: CHIP functions as a novel
suppressor of tumour angiogenesis with prognostic significance in
human gastric cancer. Gut. 62:496–508. 2013. View Article : Google Scholar
|
|
28
|
Tsuchiya M, Nakajima Y, Hirata N,
Morishita T, Kishimoto H, Kanda Y and Kimura K: Ubiquitin ligase
CHIP suppresses cancer stem cell properties in a population of
breast cancer cells. Biochem Biophys Res Commun. 452:928–932. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Torres J and Pulido R: The tumor
suppressor PTEN is phosphorylated by the protein kinase CK2 at its
C terminus. Implications for PTEN stability to proteasome-mediated
degradation. J Biol Chem. 276:993–998. 2001. View Article : Google Scholar
|
|
30
|
Brazil DP, Yang ZZ and Hemmings BA:
Advances in protein kinase B signalling: AKTion on multiple fronts.
Trends Biochem Sci. 29:233–242. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lv Y, Song S, Zhang K, Gao H and Ma R:
CHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cells.
PLoS One. 8:e833122013. View Article : Google Scholar :
|
|
32
|
Ahmed SF, Deb S, Paul I, Chatterjee A,
Mandal T, Chatterjee U and Ghosh MK: The chaperone-assisted E3
ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN
for proteasomal degradation. J Biol Chem. 287:15996–16006. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Sarkar S, Brautigan DL, Parsons SJ and
Larner JM: Androgen receptor degradation by the E3 ligase CHIP
modulates mitotic arrest in prostate cancer cells. Oncogene.
33:26–33. 2014. View Article : Google Scholar :
|
|
34
|
Jang KW, Lee KH, Kim SH, Jin T, Choi EY,
Jeon HJ, Kim E, Han YS and Chung JH: Ubiquitin ligase CHIP induces
TRAF2 proteasomal degradation and NF-κB inactivation to regulate
breast cancer cell invasion. J Cell Biochem. 112:3612–3620. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Henshall DC, Araki T, Schindler CK, Lan
JQ, Tiekoter KL, Taki W and Simon RP: Activation of
Bcl-2-associated death protein and counter-response of Akt within
cell populations during seizure-induced neuronal death. J Neurosci.
22:8458–8465. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Datta SR, Dudek H, Tao X, Masters S, Fu H,
Gotoh Y and Greenberg ME: Akt phosphorylation of BAD couples
survival signals to the cell-intrinsic death machinery. Cell.
91:231–241. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Roy MJ, Vom A, Czabotar PE and Lessene G:
Cell death and the mitochondria: Therapeutic targeting of the BCL-2
family-driven pathway. Br J Pharmacol. 171:1973–1987. 2014.
View Article : Google Scholar :
|
|
38
|
Swanson PJ, Kuslak SL, Fang W, Tze L,
Gaffney P, Selby S, Hippen KL, Nunez G, Sidman CL and Behrens TW:
Fatal acute lymphoblastic leukemia in mice transgenic for B
cell-restricted Bcl-xL and c-myc. J Immunol. 172:6684–6691. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Lee JT, Lehmann BD, Terrian DM, Chappell
WH, Stivala F, Libra M, Martelli AM, Steelman LS and McCubrey JA:
Targeting prostate cancer based on signal transduction and cell
cycle pathways. Cell Cycle. 7:1745–1762. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Alan Diehl J, Cheng M and Martine F:
Roussel and Sherr CJ: Glycogen synthase kinase-3b regulates cyclin
D1 proteolysis and subcellular localization. Genes Dev.
12:3499–3511. 1998. View Article : Google Scholar
|
|
41
|
Shaw M, Cohen P and Alessi DR: The
activation of protein kinase B by H2O2 or
heat shock is mediated by phosphoinositide 3-kinase and not by
mitogen-activated protein kinase-activated protein kinase-2.
Biochem J. 336:241–246. 1998. View Article : Google Scholar
|
|
42
|
Zhang BG, Li JF, Yu BQ, Zhu ZG, Liu BY and
Yan M: microRNA-21 promotes tumor proliferation and invasion in
gastric cancer by targeting PTEN. Oncol Rep. 27:1019–1026. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Vazquez F, Ramaswamy S, Nakamura N and
Sellers WR: Phosphorylation of the PTEN tail regulates protein
stability and function. Mol Cell Biol. 20:5010–5018. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Hill R and Wu H: PTEN, stem cells, and
cancer stem cells. J Biol Chem. 284:11755–11759. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Biswas K, Sarkar S, Du K, Brautigan DL,
Abbas T and Larner JM: The E3 ligase CHIP mediates p21 degradation
to maintain radio-resistance. Mol Cancer Res. 15:651–659. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Canaff L, Vanbellinghen JF, Kanazawa I,
Kwak H, Garfield N, Vautour L and Hendy GN: Menin missense mutants
encoded by the MEN1 gene that are targeted to the proteasome:
Restoration of expression and activity by CHIP siRNA. J Clin
Endocrinol Metab. 97:E282–E291. 2012. View Article : Google Scholar
|
|
47
|
Massagué J and Gomis RR: The logic of
TGFbeta signaling. FEBS Lett. 580:2811–2820. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhou W, He MR, Jiao HL, He LQ, Deng DL,
Cai JJ, Xiao ZY, Ye YP, Ding YQ, Liao WT, et al: The
tumor-suppressor gene LZTS1 suppresses colorectal cancer
proliferation through inhibition of the AKT-mTOR signaling pathway.
Cancer Lett. 360:68–75. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Roy SK, Srivastava RK and Shankar S:
Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of
FOXO transcription factor, leading to cell cycle arrest and
apoptosis in pancreatic cancer. J Mol Signal. 5:102010. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Cui YM, Jiang D, Zhang SH, Wu P, Ye YP,
Chen CM, Tang N, Liang L, Li TT, Qi L, et al: FOXC2 promotes
colorectal cancer proliferation through inhibition of FOXO3a and
activation of MAPK and AKT signaling pathways. Cancer Lett.
353:87–94. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Singh M, Yelle N, Venugopal C and Singh
SK: EMT: Mechanisms and therapeutic implications. Pharmacol Ther.
182:80–94. 2018. View Article : Google Scholar
|
|
52
|
Werb Z: ECM and cell surface proteolysis:
Regulating cellular ecology. Cell. 91:439–442. 1997. View Article : Google Scholar
|
|
53
|
Lukaszewicz-Zając M, Mroczko B and
Szmitkowski M: Gastric cancer - The role of matrix
metalloproteinases in tumor progression. Clin Chim Acta.
412:1725–1730. 2011. View Article : Google Scholar
|
|
54
|
Rao JS: Molecular mechanisms of glioma
invasiveness: The role of proteases. Nat Rev Cancer. 3:489–501.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Dass K, Ahmad A, Azmi AS, Sarkar SH and
Sarkar FH: Evolving role of uPA/uPAR system in human cancers.
Cancer Treat Rev. 34:122–136. 2008. View Article : Google Scholar
|
|
56
|
Yuan ZL, Guan YJ, Chatterjee D and Chin
YE: Stat3 dimerization regulated by reversible acetylation of a
single lysine residue. Science. 307:269–273. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Nalla AK, Gorantla B, Gondi CS, Lakka SS
and Rao JS: Targeting MMP-9, uPAR, and cathepsin B inhibits
invasion, migration and activates apoptosis in prostate cancer
cells. Cancer Gene Ther. 17:599–613. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Gurzu S, Turdean S, Kovecsi A, Contac AO
and Jung I: Epithelial-mesenchymal, mesenchymal-epithelial, and
endothelial-mesenchymal transitions in malignant tumors: An update.
World J Clin Cases. 3:393–404. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Xu T, Zhou Q, Zhou J, Huang Y, Yan Y, Li
W, Wang C, Hu G, Lu Y and Chen J: Carboxyl terminus of
Hsp70-interacting protein (CHIP) contributes to human glioma
oncogenesis. Cancer Sci. 102:959–966. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Wen J, Luo KJ, Hu Y, Yang H and Fu JH:
Metastatic lymph node CHIP expression is a potential prognostic
marker for resected esophageal squamous cell carcinoma patients.
Ann Surg Oncol. 20:1668–1675. 2013. View Article : Google Scholar : PubMed/NCBI
|
