Ulcerated gastric leiomyoma causing massive upper gastrointestinal bleeding: A case report

Ramai,Daryl; Tan,Qiuxue  T.; Nigar,Sofia; Ofori,Emmanuel; Etienne,Denzil; Reddy,Madhavi

doi:10.3892/mco.2018.1597

Ulcerated gastric leiomyoma causing massive upper gastrointestinal bleeding: A case report

Authors:
- Daryl Ramai
- Qiuxue T. Tan
- Sofia Nigar
- Emmanuel Ofori
- Denzil Etienne
- Madhavi Reddy
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Affiliations: Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Academic Affiliate of The Icahn School of Medicine at Mount Sinai, Clinical Affiliate of The Mount Sinai Hospital, Brooklyn, New York, NY 11201, USA, Department of Anatomical Sciences, St. George's University School of Medicine, True Blue, Grenada, West Indies
Published online on: March 26, 2018 https://doi.org/10.3892/mco.2018.1597
Pages: 671-674

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Abstract

Leiomyomas are rare, benign submucosal tumors originating from smooth muscle cells. The clinical presentation is usually asymptomatic, with excellent prognosis. We herein report the case of a 68‑year‑old female with a solitary leiomyoma found during esophagogastroduodenoscopy for hematemesis. Histopathological examination revealed smooth muscle proliferation supported by positive staining for smooth muscle myosin heavy chain and negative staining for CD117 and S‑100, consistent with the marker expression pattern of leiomyoma. We report on the clinical presentation of this case, and discuss the origin, epidemiology, treatment and management of leiomyomas.

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