[Retracted] Generation of induced pluripotent stem cells using skin fibroblasts from patients with myocardial infarction under feeder-free conditions
- Jun-Quan Li
- Ming Cheng
- Wei-Chen Tian
- Jian Zhang
Affiliations: Department of Cardiac Surgery, The Second Affiliated Hospital, Harbin Medical University, Nangang, Harbin, Heilongjiang 150086, P.R. China, Department of Surgery, The Affiliated Hospital of Medical College, Qingdao University, Qingdao, Shandong 266003, P.R. China
- Published online on: May 27, 2014 https://doi.org/10.3892/mmr.2014.2272
Copyright: © Li
et al. This is an open access article distributed under the
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Commons Attribution License [CC BY_NC 3.0].
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After the publication of the article, the authors decided they wished to retract their manuscript for the following reasons.
We wish to retract our research article entitled ‘Generation of induced pluripotent stem cells using skin fibroblasts from patients with myocardial infarction under feeder-free conditions’ published on the Molecular Medicine Reports 9: 837-842, 2014. In this article, we generated human iPSCs from skin fibroblasts from myocardial infarction patients in feeder-independent conditions. However, in subsequent researches, all of the cells generated and believed to be iPSCs showed negative expression of the pluripotent markers, Nanog and Rex1, and the cell surface marker, SSEA-1 and SSEA-4. Therefore we think the established iPS cells might not be real pluripotent stem cells. Based on the above mentioned, we ascertained that there must have some serious disadvantages in our design of experiment fundamentally. As a result, all authors involved unanimously agreed to retract this article and redesign our experiment. We deeply apologize to the readers for any inconvenience caused by this retraction. [the original article was published in the Molecular Medicine Reports 9: 837-842, 2014 DOI: 10.3892/mmr.2014.1885]