1
|
Goldring MB: Update on the biology of the
chondrocyte and new approaches to treating cartilage diseases. Best
Pract Res Clin Rheumatol. 20:1003–1025. 2006. View Article : Google Scholar : PubMed/NCBI
|
2
|
Guo FJ, Xiong Z, Lu X, Ye M, Han X and
Jiang R: ATF6 upregulates XBP1S and inhibits ER stress-mediated
apoptosis in osteoarthritis cartilage. Cell Signal. 26:332–342.
2014. View Article : Google Scholar
|
3
|
Goldring MB and Goldring SR:
Osteoarthritis. J Cell Physiol. 213:626–634. 2007. View Article : Google Scholar : PubMed/NCBI
|
4
|
Swingler TE, Wheeler G, Carmont V, Elliott
HR, Barter MJ, Abu-Elmagd M, Donell ST, Boot-Handford RP,
Hajihosseini MK, Münsterberg A, et al: The expression and function
of microRNAs in chondrogenesis and osteoarthritis. Arthritis Rheum.
64:1909–1919. 2012. View Article : Google Scholar
|
5
|
Bartel DP: MicroRNAs: Target recognition
and regulatory functions. Cell. 136:215–233. 2009. View Article : Google Scholar : PubMed/NCBI
|
6
|
Filipowicz W, Bhattacharyya SN and
Sonenberg N: Mechanisms of post-transcriptional regulation by
microRNAs: Are the answers in sight? Nat Rev Genet. 9:102–114.
2008. View
Article : Google Scholar : PubMed/NCBI
|
7
|
Wu C, Tian B, Qu X, Liu F, Tang T, Qin A,
Zhu Z and Dai K: MicroRNAs play a role in chondrogenesis and
osteoarthritis (Review). Int J Mol Med. 34:13–23. 2014.PubMed/NCBI
|
8
|
Zhang Y, Jia J, Yang S, Liu X, Ye S and
Tian H: MicroRNA-21 controls the development of osteoarthritis by
targeting GDF-5 in chondrocytes. Exp Mol Med. 46:e792014.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Li X, Kroin JS, Kc R, Gibson G, Chen D,
Corbett GT, Pahan K, Fayyaz S, Kim JS, van Wijnen AJ, et al:
Altered Spinal microRNA-146a and the microRNA-183 cluster
contribute to osteoarthritic pain in knee joints. J Bone and Miner
Res. 28:2512–2522. 2013. View Article : Google Scholar
|
10
|
Song J, Kim D, Lee CH, Lee MS, Chun CH and
Jin EJ: MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during
pathogenesis of osteoarthritis. J Biomed Sci. 20:312013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Vonk LA, Kragten AH, Dhert WJ, Saris DB
and Creemers LB: Overexpression of hsa-miR-148a promotes cartilage
production and inhibits cartilage degradation by osteoarthritic
chondrocytes. Osteoarthritis Cartilage. 22:145–153. 2014.
View Article : Google Scholar
|
12
|
Park SJ, Cheon EJ, Lee MH and Kim HA:
MicroRNA-127-5p regulates matrix metalloproteinase 13 expression
and interleukin-1β-induced catabolic effects in human chondrocytes.
Arthritis Rheum. 65:3141–3152. 2013. View Article : Google Scholar : PubMed/NCBI
|
13
|
Devlin C, Greco S, Martelli F and Ivan M:
miR-210: More than a silent player in hypoxia. IUBMB Life.
63:94–100. 2011.PubMed/NCBI
|
14
|
Bodempudi V, Hergert P, Smith K, Xia H,
Herrera J, Peterson M, Khalil W, Kahm J, Bitterman PB and Henke CA:
miR-210 promotes IPF fibroblast proliferation in response to
hypoxia. Am J Physiol Lung Cell Mol Physiol. 307:L283–L294. 2014.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Li L, Huang K, You Y, Fu X, Hu L, Song L
and Meng Y: Hypoxia-induced miR-210 in epithelial ovarian cancer
enhances cancer cell viability via promoting proliferation and
inhibiting apoptosis. Int J Oncol. 44:2111–2120. 2014.PubMed/NCBI
|
16
|
Chang Z, Huo L, Wu Y and Zhang P: HIF-1 α
had pivotal effects on downregulation of miR-210 decreasing
viability and inducing apoptosis in hypoxic chondrocytes.
Scientific World-Journal. 2014:8763632014. View Article : Google Scholar
|
17
|
Pfaffl MW: A new mathematical model for
relative quantification in real-time RT-PCR. Nucleic Acids Res.
29:e452001. View Article : Google Scholar : PubMed/NCBI
|
18
|
Burrage PS, Mix KS and Brinckerhoff CE:
Matrix metalloproteinases: Role in arthritis. Front Biosci.
11:529–543. 2005. View
Article : Google Scholar : PubMed/NCBI
|
19
|
Mackie EJ, Tatarczuch L and Mirams M: The
skeleton: A multi-functional complex organ. The growth plate
chondrocyte and endochondral ossification. J Endocrinol.
211:109–121. 2011. View Article : Google Scholar : PubMed/NCBI
|
20
|
Loeser RF: Osteoarthritis year in review
2013: Biology. Osteoarthritis Cartilage. 21:1436–1442. 2013.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Lawrence RC, Felson DT, Helmick CG, Arnold
LM, Choi H, Deyo RA, Gabriel S, Hirsch R, Hochberg MC, Hunder GG,
et al: Estimates of the prevalence of arthritis and other rheumatic
conditions in the United States: Part II. Arthritis Rheum.
58:26–35. 2008. View Article : Google Scholar : PubMed/NCBI
|
22
|
Loeser RF, Goldring SR, Scanzello CR and
Goldring MB: Osteoarthritis: A disease of the joint as an organ.
Arthritis Rheum. 64:1697–1707. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Felson DT, Lawrence RC, Dieppe PA, Hirsch
R, Helmick CG, Jordan JM, Kington RS, Lane NE, Nevitt MC, Zhang Y,
et al: Osteoarthritis: New insights. Part 1: The disease and its
risk factors. Ann Intern Med. 133:635–646. 2000. View Article : Google Scholar : PubMed/NCBI
|
24
|
Blagojevic M, Jinks C, Jeffery A and
Jordan K: Risk factors for onset of osteoarthritis of the knee in
older adults: A systematic review and meta-analysis. Osteoarthritis
Cartilage. 18:24–33. 2010. View Article : Google Scholar
|
25
|
Staal B, Williams BO, Beier F, Vande Woude
GF and Zhang YW: Cartilage-specific deletion of Mig-6 results in
osteoarthritis-like disorder with excessive articular chondrocyte
proliferation. Proc Natl Acad Sci USA. 111:2590–2595. 2014.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Tchetina EV: Developmental mechanisms in
articular cartilage degradation in osteoarthritis. Arthritis.
2011:6839702011. View Article : Google Scholar : PubMed/NCBI
|
27
|
Aigner T, Fundel K, Saas J, Gebhard PM,
Haag J, Weiss T, Zien A, Obermayr F, Zimmer R and Bartnik E:
Large-scale gene expression profiling reveals major pathogenetic
pathways of cartilage degeneration in osteoarthritis. Arthritis
Rheum. 54:3533–3544. 2006. View Article : Google Scholar : PubMed/NCBI
|
28
|
Kobayashi T, Lu J, Cobb BS, Rodda SJ,
McMahon AP, Schipani E, Merkenschlager M and Kronenberg HM:
Dicer-dependent pathways regulate chondrocyte proliferation and
differentiation. Proc Natl Acad Sci USA. 105:1949–1954. 2008.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Tardif G, Hum D, Pelletier JP, Duval N and
Martel-Pelletier J: Regulation of the IGFBP-5 and MMP-13 genes by
the microRNAs miR-140 and miR-27a in human osteoarthritic
chondrocytes. BMC Musculoskelet Disord. 10:1482009. View Article : Google Scholar : PubMed/NCBI
|
30
|
Akhtar N, Rasheed Z, Ramamurthy S,
Anbazhagan AN, Voss FR and Haqqi TM: MicroRNA-27b regulates the
expression of matrix metalloproteinase 13 in human osteoarthritis
chondrocytes. Arthritis Rheum. 62:1361–1371. 2010. View Article : Google Scholar : PubMed/NCBI
|
31
|
Abouheif MM, Nakasa T, Shibuya H, Niimoto
T, Kongcharoensombat W and Ochi M: Silencing microRNA-34a inhibits
chondrocyte apoptosis in a rat osteoarthritis model in vitro.
Rheumatology (Oxford). 49:2054–2060. 2010. View Article : Google Scholar
|
32
|
Heikkilä M, Pasanen A, Kivirikko KI and
Myllyharju J: Roles of the human hypoxia-inducible factor (HIF)-3α
variants in the hypoxia response. Cell Mol Life Sci. 68:3885–3901.
2011. View Article : Google Scholar
|
33
|
Ando H, Natsume A, Iwami K, Ohka F,
Kuchimaru T, Kizaka-Kondoh S, Ito K, Saito K, Sugita S, Hoshino T
and Wakabayashi T: A hypoxia-inducible factor (HIF)-3α splicing
variant, HIF-3α4 impairs angiogenesis in hypervascular malignant
meningiomas with epigenetically silenced HIF-3α4. Biochem Biophys
Res Commun. 433:139–144. 2013. View Article : Google Scholar : PubMed/NCBI
|
34
|
Murphy CL, Thoms BL, Vaghjiani RJ and
Lafont JE: Hypoxia, HIF-mediated articular chondrocyte function:
Prospects for cartilage repair. Arthritis Res Ther. 11:2132009.
View Article : Google Scholar
|
35
|
Schipani E, Ryan HE, Didrickson S,
Kobayashi T, Knight M and Johnson RS: Hypoxia in cartilage:
HIF-1alpha is essential for chondrocyte growth arrest and survival.
Genes Dev. 15:2865–2876. 2001.PubMed/NCBI
|