New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review)

  • Authors:
    • Salvatore Gizzo
    • Marco Noventa
    • Michela Quaranta
    • Roberta Venturella
    • Amerigo Vitagliano
    • Michele Gangemi
    • Donato D'Antona
  • View Affiliations

  • Published online on: September 19, 2016     https://doi.org/10.3892/mmr.2016.5749
  • Pages: 4037-4041
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Abstract

In the era of very late, or advanced, motherhood, in which ‘egg banks’, ʻsocialʼ egg‑freezing, egg donation and surrogacy represent a potential solution to a number of obstacles to human reproduction, what is the role of scientists and clinicians involved in assisted reproduction? In light of the apprehension that, in the future, through fertility treatment infertility may be passed on to the offspring, boundaries of medical vs. ʻsocialʼ infertility are being created. Scientists and clinicians are joining forces in a synergistic effort to improve the effectiveness of infertility care by introducing novel therapeutic protocols with the intent of customising care and improving cost‑effectiveness, testing novel drugs and formulations, and searching for novel markers (for estimating biological age) and nomograms (to optimise the yield of a controlled ovarian hyperstimulation cycle). On the other hand, political, social and health institutions are doing little to educate young women with respect to disinformation and to increase their awareness regarding age as the predominant factor that contributes towards the decline in fertility. Nevertheless, despite the great advances that have been made, 38 years after the birth of the first baby via in vitro fertilisation, the intricate road leading from the antral follicle to the fully developed baby continues to be designated as being too ‘expensive’, ‘empirical’, ‘mysterious’ or ‘bound by ethics’, with few significant improvements in terms of real cost‑effectiveness.
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November-2016
Volume 14 Issue 5

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Gizzo S, Noventa M, Quaranta M, Venturella R, Vitagliano A, Gangemi M and D'Antona D: New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review). Mol Med Rep 14: 4037-4041, 2016
APA
Gizzo, S., Noventa, M., Quaranta, M., Venturella, R., Vitagliano, A., Gangemi, M., & D'Antona, D. (2016). New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review). Molecular Medicine Reports, 14, 4037-4041. https://doi.org/10.3892/mmr.2016.5749
MLA
Gizzo, S., Noventa, M., Quaranta, M., Venturella, R., Vitagliano, A., Gangemi, M., D'Antona, D."New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review)". Molecular Medicine Reports 14.5 (2016): 4037-4041.
Chicago
Gizzo, S., Noventa, M., Quaranta, M., Venturella, R., Vitagliano, A., Gangemi, M., D'Antona, D."New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review)". Molecular Medicine Reports 14, no. 5 (2016): 4037-4041. https://doi.org/10.3892/mmr.2016.5749