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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2016 Volume 14 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

microRNAs involved in Parkinson's disease: A systematic review

Franciele Cascaes da Silva, Rodrigo da Rosa Iop, Giovanna Grunewald Vietta, Diego Alessandro Kair, Paulo José Barbosa Gutierres Filho, José Gustavo Souza de Alvarenga, Rudney da Silva
Pages: 4015-4022
Published online on: 22 September 2016

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Review Open Access

Molecular screening strategies for NF1-like syndromes with café-au-lait macules (Review)

Jia Zhang, Ming Li, Zhirong Yao
Pages: 4023-4029
Published online on: 22 September 2016

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Article Open Access

Insights into the pathogenesis of Mycoplasma pneumoniae (Review) Corrigendum in /10.3892/mmr.2017.8324

Jun He, Mihua Liu, Zhufeng Ye, Tianping Tan, Xinghui Liu, Xiaoxing You, Yanhua Zeng, Yimou Wu
Pages: 4030-4036
Published online on: 23 September 2016

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Review

New frontiers in human assisted reproduction ‑ from research to clinical practice: Several considerations (Review)

Salvatore Gizzo, Marco Noventa, Michela Quaranta, Roberta Venturella, Amerigo Vitagliano, Michele Gangemi, Donato D'Antona
Pages: 4037-4041
Published online on: 19 September 2016

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Article Open Access

Matrine induces cell cycle arrest and apoptosis with recovery of the expression of miR-126 in the A549 non-small cell lung cancer cell line

Qi An, Chao Han, Yubing Zhou, Feng Li, Duolu Li, Xiaojian Zhang, Zujiang Yu, Zhenfeng Duan, Quancheng Kan
Pages: 4042-4048
Published online on: 20 September 2016

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Article Open Access

Nagashima-type palmoplantar keratosis in a Chinese Han population

Jia Zhang, Guolong Zhang, Cheng Ni, Ruhong Cheng, Jianying Liang, Ming Li, Zhirong Yao
Pages: 4049-4054
Published online on: 21 September 2016

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Article Open Access

Involvement of peroxisome proliferator activated receptor-γ in the anti-inflammatory effects of atorvastatin in oxygen-glucose deprivation/reperfusion-stimulated RAW264.7 murine macrophages

Hong‑Yan Li, Yan‑Yan Su, Yun‑Fang Zhang, Zhi‑Qiang Liu, Bao‑Jun Hua
Pages: 4055-4062
Published online on: 15 September 2016

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Article Open Access

Chlorogenic acid prevents isoproterenol-induced DNA damage in vascular smooth muscle cells

Jingshuai Wang, Jiyang Li, Jie Liu, Mengjiao Xu, Xiaowen Tong, Jianjun Wang
Pages: 4063-4068
Published online on: 15 September 2016

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Article Open Access

Gap junction inhibition by heptanol increases ventricular arrhythmogenicity by reducing conduction velocity without affecting repolarization properties or myocardial refractoriness in Langendorff-perfused mouse hearts

Gary Tse, Jie Ming Yeo, Vivian Tse, Joseph Kwan, Bing Sun
Pages: 4069-4074
Published online on: 13 September 2016

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Article Open Access

Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis

Jinjiang Yang, Ying Lu, Ai Guo
Pages: 4075-4082
Published online on: 23 September 2016

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Article Open Access

Enhanced expression of Cx43 and gap junction communication in vascular smooth muscle cells of spontaneously hypertensive rats

Li‑Jie Wang, Wei‑Dong Liu, Liang Zhang, Ke‑Tao Ma, Lei Zhao, Wen‑Yan Shi, Wen‑Wen Zhang, Ying‑Zi Wang, Li Li, Jun‑Qiang Si
Pages: 4083-4090
Published online on: 26 September 2016

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Article Open Access

Glycogen synthase kinase‑3β is required for epithelial‑mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions Retraction in /10.3892/mmr.2020.11523

Jia Guo, Lili Yang, Yingjin Qiao, Zhangsuo Liu
Pages: 4091-4098
Published online on: 26 September 2016

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Article Open Access

Transcriptional profile of SH-SY5Y human neuroblastoma cells transfected by Toxoplasma rhoptry protein 16

Weiwei Fan, Shuang Chang, Xiumei Shan, Dejun Gao, Steven Qian Zhang, Jin Zhang, Nan Jiang, Duan Ma, Zuohua Mao
Pages: 4099-4108
Published online on: 21 September 2016

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Article Open Access

Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome

Hua Lin, Weiguo Sui, Wuxian Li, Qiupei Tan, Jiejing Chen, Xiuhua Lin, Hui Guo, Minglin Ou, Wen Xue, Ruohan Zhang, Yong Dai
Pages: 4109-4118
Published online on: 26 September 2016

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Article Open Access

Dysregulation of GTPase IMAP family members in hepatocellular cancer

Zhen Huang, Wei Zhang, Chunhai Gao, Baoju Ji, Xiuwen Chi, Wei Zheng, Hai Lan Wang
Pages: 4119-4123
Published online on: 22 September 2016

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Article Open Access

Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1

Shi Deng, Tao Jin, Li Zhang, Hong Bu, Peng Zhang
Pages: 4124-4134
Published online on: 13 September 2016

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Article Open Access

miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1

Hai‑Xiang Gao, Li Yan, Chunzhi Li, Lian‑Mei Zhao, Wei Liu
Pages: 4135-4143
Published online on: 23 September 2016

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Article Open Access

Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats

Bo Liu, Fei Li, Jingshan Shi, Danli Yang, Yuanyuan Deng, Qihai Gong
Pages: 4144-4152
Published online on: 26 September 2016

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Article Open Access

Apolipoprotein E genotyping using PCR-GoldMag lateral flow assay and its clinical applications

Ting Lian, Wenli Hui, Xianying Li, Chao Zhang, Juanli Zhu, Rui Li, Yinsheng Wan, Yali Cui
Pages: 4153-4161
Published online on: 23 September 2016

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Article Open Access

Cerebral ischemic post‑conditioning induces autophagy inhibition and a HMGB1 secretion attenuation feedback loop to protect against ischemia reperfusion injury in an oxygen glucose deprivation cellular model Corrigendum in /10.3892/mmr.2025.13641

Jue Wang, Dong Han, Miao Sun, Juan Feng
Pages: 4162-4172
Published online on: 19 September 2016

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Article Open Access

Upregulation of DAPK contributes to homocysteine-induced endothelial apoptosis via the modulation of Bcl2/Bax and activation of caspase 3

Xin Tian, Yongfeng Shi, Ning Liu, Youyou Yan, Tianyi Li, Peiyan Hua, Bin Liu
Pages: 4173-4179
Published online on: 12 September 2016

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Article Open Access

Arsenic trioxide and triptolide synergistically induce apoptosis in the SKM‑1 human myelodysplastic syndrome cell line

Hai‑Ying Hua, Hua‑Qiang Gao, Ai‑Ning Sun, Jian‑Nong Cen, Li‑Li Wu
Pages: 4180-4186
Published online on: 26 September 2016

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Article Open Access

Interferon‑γ alters the microRNA profile of umbilical cord‑derived mesenchymal stem cells

Ying Chi, Junjie Cui, Youwei Wang, Wenjing Du, Fang Chen, Zongjin Li, Fengxia Ma, Baoquan Song, Fangyun Xu, Qingjun Zhao, Zhibo Han, Zhongchao Han
Pages: 4187-4197
Published online on: 19 September 2016

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Article Open Access

Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+‑mediated mitochondrial pathway

Le Xie, Guang‑Hong Xiang, Tao Tang, Yan Tang, Ling‑Yun Zhao, Dong Liu, You‑Ren Zhang, Jin‑Tian Tang, Shen Zhou, Da‑Hua Wu
Pages: 4198-4208
Published online on: 26 September 2016

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Article Open Access

Efficacy of umbilical cord-derived mesenchymal stem cell-based therapy for osteonecrosis of the femoral head: A three-year follow-up study

Chun Chen, Zhiguo Qu, Xiaoguang Yin, Chunyu Shang, Qiang Ao, Yongquan Gu, Ying Liu
Pages: 4209-4215
Published online on: 16 September 2016

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Article Open Access

Trimetazidine protects against cardiac ischemia/reperfusion injury via effects on cardiac miRNA‑21 expression, Akt and the Bcl‑2/Bax pathway

Ning Ma, Jingyun Bai, Weihua Zhang, Hong Luo, Xin Zhang, Donghai Liu, Chenhui Qiao
Pages: 4216-4222
Published online on: 26 September 2016

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Article Open Access

Long non-coding RNAs regulate effects of β-crystallin B2 on mouse ovary development

Qian Gao, Hanxiao Ren, Mingkun Chen, Ziguang Niu, Haibo Tao, Yin Jia, Jianrong Zhang, Wenjie Li
Pages: 4223-4231
Published online on: 22 September 2016

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Article Open Access

Differences in atrial fibrillation‑associated proteins between the left and right atrial appendages from patients with rheumatic mitral valve disease: A comparative proteomic analysis Corrigendum in /10.3892/mmr.2018.9218

Hai Liu, Guangxian Chen, Hongsheng Zheng, Han Qin, Mengya Liang, Kangni Feng, Zhongkai Wu
Pages: 4232-4242
Published online on: 26 September 2016

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Article

A silkworm infection model to investigate Vibrio vulnificus virulence genes

Mai Yamamoto, Takashige Kashimoto, Yukihiro Yoshimura, Nao Tachibana, Shiho Kuroda, Yoshiko Miki, Sou Kitabayashi, Ping Tong, Jianbo Xiao, Koichi Tanaka, Hiroshi Hamamoto, Kazuhisa Sekimizu, Koichiro Yamamoto
Pages: 4243-4247
Published online on: 26 September 2016

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Article

Hypoxia mediates osteocyte ORP150 expression and cell death in vitro

Monica Montesi, Katharina Jähn, Lynda Bonewald, Susanna Stea, Barbara Bordini, Alina Beraudi
Pages: 4248-4254
Published online on: 26 September 2016

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Article

Identification and clinical significance of an elevated level of serum aminoacylase-1 autoantibody in patients with hepatitis B virus-related liver cirrhosis

Xiaomin He, Yu Hong, Xiaomei Wang, Xiaohong Zhang, Jiang Long, Hai Li, Bei Zhang, Suhong Chen, Qiqi Liu, Hongyi Li, Xiaoming Wang, Xiaojuan Ou, Jian Huang
Pages: 4255-4262
Published online on: 14 September 2016

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Article

Effects of polysaccharides isolated from Inonotus obliquus against hydrogen peroxide-induced oxidative damage in RINm5F pancreatic β-cells

Ye Chan Sim, Jong Seok Lee, Sarah Lee, Youn Kyoung Son, Jung‑Eun Park, Jeong Eun Song, Suk‑Jin Ha, Eock Kee Hong
Pages: 4263-4270
Published online on: 22 September 2016

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Article

MicroRNA-181a promotes proliferation and inhibits apoptosis by suppressing CFIm25 in osteosarcoma

Zhong‑Jiao Zhu, Peng Huang, Yan‑Xue Chong, Li‑Xin Kang, Xing Huang, Zhong‑Xiu Zhu, Lin Nie
Pages: 4271-4278
Published online on: 14 September 2016

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Article

Matrix metalloproteinase 9 may be involved in contraction of vascular smooth muscle cells in an in vitro rat model of subarachnoid hemorrhage

Baoqi Dang, Haitao Shen, Haiying Li, Min Zhu, Chunhua Guo, Weichun He
Pages: 4279-4284
Published online on: 13 September 2016

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Article

An outbreak of HCV genotype 6a and 2a infection in South China: Confirmation of iatrogenic transmission by phylogenetic analysis of the NS5B region

Xiaoqiong Shao, Qiumin Luo, Qingxian Cai, Fulong Zhang, Jiangyun Zhu, Ying Liu, Zhixin Zhao, Zhiliang Gao, Xiaohong Zhang
Pages: 4285-4292
Published online on: 13 September 2016

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Article

Cyclical compressive stress induces differentiation of rat primary mandibular condylar chondrocytes through phosphorylated myosin light chain II

Limin Liu, Lin Chen, Zhihui Mai, Zhuli Peng, Kafung Yu, Guanqi Liu, Hong Ai
Pages: 4293-4300
Published online on: 26 September 2016

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Article

Flow cytometric analyses of the viability, surface marker expression and function of lymphocytes from children following cryopreservation

Xi Chen, Hui Zhang, Wenjun Mou, Zhan Qi, Xiaoya Ren, Guoliang Wang, Hong Jiao, Xiaohui Kong, Jingang Gui
Pages: 4301-4308
Published online on: 26 September 2016

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Article

Integrated analysis of DNA methylation and RNA‑sequencing data in Down syndrome

Jiantao Zhang, Wenli Zhou, Ying Liu, Nan Li
Pages: 4309-4314
Published online on: 26 September 2016

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Article

Proliferation of metanephric mesenchymal cells is inhibited by miR-743a-mediated WT1 suppression in vitro

Mingming Xue, Yuru Zhou, Xiaoyu Liu, Dongsheng Ni, Yanxia Hu, Yaoshui Long, Pan Ju, Qin Zhou
Pages: 4315-4320
Published online on: 22 September 2016

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Article

Cysteine‑rich 61 RNA interference inhibits pathological angiogenesis via the phosphatidylinositol 3‑kinase/Akt‑vascular endothelial growth factor signaling pathway in endothelial cells

Yu Di, Yiou Zhang, Linping Hui, Hongwei Yang, Yang Yang, Aiyuan Wang, Xiaolong Chen
Pages: 4321-4327
Published online on: 26 September 2016

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Article

Effect of BMPs and Wnt3a co-expression on the osteogenetic capacity of osteoblasts

Wendong Ruan, Yuan Xue, Yaqi Zong, Chao Sun
Pages: 4328-4334
Published online on: 12 September 2016

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Article

A3 adenosine receptor agonist, CF102, protects against hepatic ischemia/reperfusion injury following partial hepatectomy

Gil Ohana, Shira Cohen, Lea Rath‑Wolfson, Pnina Fishman
Pages: 4335-4341
Published online on: 19 September 2016

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Article

Molecular mechanisms of melatonin in the reversal of LPS-induced EMT in peritoneal mesothelial cells

Shuaishuai Shi, Yiqiang Zhang, Wenbin Wen, Yine Zhao, Lin Sun
Pages: 4342-4348
Published online on: 16 September 2016

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Article

Diosgenin‑induced autophagy and apoptosis in a human prostate cancer cell line

Chao Nie, Jie Zhou, Xiaokang Qin, Xianming Shi, Qingqi Zeng, Jia Liu, Shihai Yan, Lei Zhang
Pages: 4349-4359
Published online on: 19 September 2016

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Article

α-lipoic acid exerts neuroprotective effects on neuronal cells by upregulating the expression of PCNA via the P53 pathway in neurodegenerative conditions

Da‑Wei Li, Ying‑Di Wang, Shi‑Yao Zhou, Wen‑Ping Sun
Pages: 4360-4366
Published online on: 20 September 2016

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Article

Identification of differentially expressed transcripts targeted by the knockdown of endogenous IFITM3

Chen Shen, Ying‑Jia Li, Qing‑Qin Yin, Wei‑Wei Jiao, Qin‑Jing Li, Jing Xiao, Lin Sun, Fang Xu, Jie‑Qiong Li, Hui Qi, A‑Dong Shen
Pages: 4367-4373
Published online on: 26 September 2016

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Article

CD38 gene-modified dendritic cells inhibit murine asthma development by increasing IL-12 production and promoting Th1 cell differentiation

Jiaoli Wang, Weiguo Zhu, Yinghu Chen, Zhendong Lin, Shenglin Ma
Pages: 4374-4382
Published online on: 21 September 2016

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Article

Expression and analyses of the HIF-1 pathway in the lungs of humans with pulmonary arterial hypertension

Wei Lei, Yuan He, Xiaorong Shui, Guoming Li, Guosen Yan, Yu Zhang, Shian Huang, Can Chen, Yuanlin Ding
Pages: 4383-4390
Published online on: 20 September 2016

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Article

Effects of adenosine stimulation on the mRNA expression of CLCNKB in the basolateral medullary thick ascending limb of the rat kidney

Haiyan Luan, Peng Wu, Mingxiao Wang, Hongyu Sui, Lili Fan, Ruimin Gu
Pages: 4391-4398
Published online on: 26 September 2016

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Article

Human parvovirus B19 antibodies induce altered membrane protein expression and apoptosis of BeWo trophoblasts

Bor‑Show Tzang, Szu‑Yi Chiang, Hsu‑Chin Chan, Chung‑Hsien Liu, Tsai‑Ching Hsu
Pages: 4399-4406
Published online on: 26 September 2016

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Article

Cardioprotective potential of Dendrobium officinale Kimura et Migo against myocardial ischemia in mice

Meng‑Meng Dou, Zhi‑Hao Zhang, Zhu‑Bo Li, Jie Zhang, Xiao‑Yan Zhao
Pages: 4407-4414
Published online on: 26 September 2016

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Article

An insertion/deletion polymorphism within the 3'‑untranslated region of COL1A2 confers susceptibility to osteoporosis

Zhen‑Song Jiang, Zhen‑Hai Hao
Pages: 4415-4421
Published online on: 21 September 2016

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Article

MicroRNA-138 inhibits migration and invasion of non-small cell lung cancer cells by targeting LIMK1 Retraction in /10.3892/mmr.2021.12209

Yanjuan Tan, Huaidong Hu, Wuyuan Tan, Longyu Jin, Jianxin Liu, Hui Zhou
Pages: 4422-4428
Published online on: 23 September 2016

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Article

Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-κB signaling pathway

Ki Rim Lee, Jong Seok Lee, Sarah Lee, Youn Kyoung Son, Ga Ryun Kim, Ye Chan Sim, Jeong Eun Song, Suk‑Jin Ha, Eock Kee Hong
Pages: 4429-4435
Published online on: 23 September 2016

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Article

Effect of Schiff base Cu(II) complexes on signaling pathways in HT-29 cells

Katarína Koňariková, Georgios A. Perdikaris, Helena Gbelcova, Lucia Andrezálová, Martin Švéda, Tomáš Ruml, Lucia Laubertová, Ingrid Žitňanová
Pages: 4436-4444
Published online on: 14 September 2016

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Article Open Access

Rab5a‑mediated autophagy regulates the phenotype and behavior of vascular smooth muscle cells

Jin‑Yun Tan, Luo‑Qi Jia, Wei‑Hao Shi, Qing He, Lei Zhu, Bo Yu
Pages: 4445-4453
Published online on: 26 September 2016

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Article

Caffeic acid, morin hydrate and quercetin partially attenuate sulfur mustard-induced cell death by inhibiting the lipoxygenase pathway

Shin Kim, Kwang‑Joon Jeong, Sung Kweon Cho, Joo‑Won Park, Woo‑Jae Park
Pages: 4454-4460
Published online on: 23 September 2016

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Review Open Access

Occupational exposure to carcinogens: Benzene, pesticides and fibers (Review)

Luca Falzone, Andrea Marconi, Carla Loreto, Sabrina Franco, Demetrios A. Spandidos, Massimo Libra
Pages: 4467-4474
Published online on: 03 October 2016

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Review Open Access

Occupational exposure to pesticides as a possible risk factor for the development of chronic diseases in humans (Review)

Silvia Gangemi, Edoardo Miozzi, Michele Teodoro, Giusi Briguglio, Annamaria De Luca, Carmela Alibrando, Irene Polito, Massimo Libra
Pages: 4475-4488
Published online on: 10 October 2016

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Review

Betulinic acid and the pharmacological effects of tumor suppression (Review)

Xia Zhang, Jingyu Hu, Yan Chen
Pages: 4489-4495
Published online on: 04 October 2016

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Label-free LC-MS/MS shotgun proteomics to investigate the anti-inflammatory effect of rCC16

Min Pang, Xin‑Yan Bai, Yan Li, Ji‑Zhong Bai, Li‑Rong Yuan, Shou‑An Ren, Xiao‑Yun Hu, Xin‑Ri Zhang, Bao‑Feng Yu, Rui Guo, Hai‑Long Wang
Pages: 4496-4504
Published online on: 12 October 2016

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NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells

Jian Wan, Yi Shan, Yibo Fan, Conghui Fan, Song Chen, Jie Sun, Lili Zhu, Long Qin, Mengjin Yu, Zhaofen Lin
Pages: 4505-4510
Published online on: 12 October 2016

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Hematopoietic stem cells as a tool for the treatment of glioblastoma multiforme

Igor S. Bryukhovetskiy, Inessa V. Dyuizen, Valeriy E. Shevchenko, Andrey S. Bryukhovetskiy, Polina V. Mischenko, Elena V. Milkina, Yuri S. Khotimchenko
Pages: 4511-4520
Published online on: 13 October 2016

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Protective effects of Centella asiatica leaf extract on dimethylnitrosamine‑induced liver injury in rats

Myung‑Joo Choi, Hong‑Mei Zheng, Jae Min Kim, Kye Wan Lee, Yu Hwa Park, Don Haeng Lee
Pages: 4521-4528
Published online on: 05 October 2016

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Quantification of the asymmetric migration of the lipophilic dyes, DiO and DiD, in homotypic co-cultures of chondrosarcoma SW-1353 cells

Tomasz P. Lehmann, Wojciech Juzwa, Krystyna Filipiak, Patrycja Sujka‑Kordowska, Maciej Zabel, Jakub Głowacki, Maciej Głowacki, Paweł P. Jagodziński
Pages: 4529-4536
Published online on: 04 October 2016

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Effect of Salvia miltiorrhiza and ligustrazine injection on myocardial ischemia/reperfusion and hypoxia/reoxygenation injury

Wendong Huang, Yongfei Yang, Zhi Zeng, Meiling Su, Qi Gao, Banghao Zhu
Pages: 4537-4544
Published online on: 11 October 2016

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Bone morphogenetic protein‑9 promotes the differentiation of mouse spleen macrophages into osteoclasts via the ALK1 receptor and ERK 1/2 pathways in vitro

Hai Li, Dahang Zhao, Shengjing Wang, Jing Ding, Li Zhao
Pages: 4545-4550
Published online on: 05 October 2016

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Evodiamine inhibits PDGF‑BB‑induced proliferation of rat vascular smooth muscle cells through the suppression of cell cycle progression and oxidative stress

Xie Ge, Si‑Yu Chen, Mei Liu, Ting‑Ming Liang, Chang Liu
Pages: 4551-4558
Published online on: 05 October 2016

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Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis

Lin Yang, Yanqing Liu, Mei Wang, Yayun Qian, Xiaoyun Dong, Hao Gu, Haibo Wang, Shiyu Guo, Tadashi Hisamitsu
Pages: 4559-4566
Published online on: 10 October 2016

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MicroRNA expression profiles of granulocytic myeloid‑derived suppressor cells from mice bearing Lewis lung carcinoma

Jingwei Jiang, Qingmin Gao, Tian Wang, Hao Lin, Qiong Zhan, Zhaohui Chu, Ruofan Huang, Xinli Zhou, Xiaohua Liang, Weijian Guo
Pages: 4567-4574
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Changes of gene expression in T lymphocytes following Golli‑MBP gene RNA interference

Juanyong Xu, Dandan Zhu, Jing Shan, Yuan Fan
Pages: 4575-4580
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MCM2 and TIP30 are prognostic markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of the gallbladder

Ziru Liu, Zhulin Yang, Song Jiang, Qiong Zou, Yuan Yuan, Jinghe Li, Daiqiang Li, Lufeng Liang, Meigui Chen, Senlin Chen
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Effect of Survivin gene therapy via lentivirus vector on the course of intervertebral disc degeneration in an in vivo rabbit model

Bin Yue, Yazhou Lin, Xuexiao Ma, Guoqing Zhang, Bohua Chen
Pages: 4593-4598
Published online on: 12 October 2016

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Dynamic expression of srGAP2 in cell nuclei and cytoplasm during the differentiation of rat neural stem cells in vitro

Qian Jiao, Li Wang, Zhichao Zhang, Yuanyuan Wang, Hanqi Yan, Wen Ma, Weilin Jin, Haixia Lu, Yong Liu
Pages: 4599-4605
Published online on: 04 October 2016

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Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma

Tian Lan, Lei Chang, Long Wu, Yufeng Yuan
Pages: 4606-4612
Published online on: 12 October 2016

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Mechanism of G9a inhibitor BIX‑01294 acting on U251 glioma cells

Ai‑Shun Guo, Yi‑Qun Huang, Xu‑Dong Ma, Rui‑Sheng Lin
Pages: 4613-4621
Published online on: 06 October 2016

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Protocadherin γ A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth

Xueyan Zhang, Katsuyoshi Takata, Wei Cui, Tomoko Miyata‑Takata, Yasuharu Sato, Mai Noujima‑Harada, Tadashi Yoshino
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Screening of differentially expressed protein kinases in bone marrow endothelial cells and the protective effects of the p38a inhibitor SB203580 on bone marrow in liver fibrosis

Bo Gao, Wang Sun, Xianzhi Meng, Dongbo Xue, Weihui Zhang
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Autophagy is involved in aldosterone‑induced mesangial cell proliferation

Min Yang, Bin Wang, Liying Miao, Xianlin Xu, Xiaozhou He
Pages: 4638-4642
Published online on: 05 October 2016

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Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact

Tian Yang, Jinyuan Wang, Yamei Pang, Xiaomin Dang, Hui Ren, Ya Liu, Mingwei Chen, Dong Shang
Pages: 4643-4649
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Analysis of altered microRNA expression profiles in the kidney tissues of ethylene glycol-induced hyperoxaluric rats

Zhuo Liu, Hongyang Jiang, Jun Yang, Tao Wang, Yufeng Ding, Jihong Liu, Shaogang Wang, Zhangqun Ye
Pages: 4650-4658
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Protective effect of resveratrol on spermatozoa function in male infertility induced by excess weight and obesity

Xiangrong Cui, Xuan Jing, Xueqing Wu, Meiqin Yan
Pages: 4659-4665
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Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment

Qingye Li, Yuxian Tang, Jing Qin, Lan Yi, Yening Yang, Juan Wang, Jie He, Qi Su, Hui Tan
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CXCL1 gene silencing inhibits HGC803 cell migration and invasion and acts as an independent prognostic factor for poor survival in gastric cancer

Liang Wang, Changhua Zhang, Jianbo Xu, Hui Wu, Jianjun Peng, Shirong Cai, Yulong He
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Collagen-binding vascular endothelial growth factor attenuates CCl4-induced liver fibrosis in mice

Kangkang Wu, Rui Huang, Hongyan Wu, Yong Liu, Chenchen Yang, Shufeng Cao, Xianglin Hou, Bing Chen, Jianwu DaI, Chao Wu
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Novel mutation of EXT2 identified in a large family with multiple osteochondromas

Xiao‑Jun Chen, Hong Zhang, Zhi‑Ping Tan, Wen Hu, Yi‑Feng Yang
Pages: 4687-4691
Published online on: 06 October 2016

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Musulju improves benign prostatic hyperplasia by regulating inflammatory and apoptotic proteins

Jae‑Yun Ju, Kyung‑Sook Chung, Se‑Yun Cheon, Hyo‑Jin An
Pages: 4692-4698
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Release from optimal compressive force suppresses osteoclast differentiation

Masaaki Ikeda, Yoshitaka Yoshimura, Takashi Kikuiri, Mino Matsuno, Tomokazu Hasegawa, Kumu Fukushima, Takako Hayakawa, Hajime Minamikawa, Kuniaki Suzuki, Junichiro Iida
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Hypoxia induces glucose uptake and metabolism of adipose‑derived stem cells

Hyoung Sook Park, Ji Hye Kim, Bo Kyung Sun, Sun U. Song, Wonhee Suh, Jong‑Hyuk Sung
Pages: 4706-4714
Published online on: 05 October 2016

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Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus

Hong Zhang, Peng He, Rongzhong Huang, Lin Sun, Siwen Liu, Jingjing Zhou, Yujie Guo, Deyu Yang, Peng Xie
Pages: 4715-4722
Published online on: 13 October 2016

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Danggui‑Sayuk‑Ga‑Osuyu‑Senggang‑Tang ameliorates cold‑induced vasoconstriction in vitro and in vivo

Kangwook Lee, Sung‑Gook Cho, Sang‑Mi Woo, Ah Jeong Kim, Kang Min Lee, Ho Yeon Go, Seung‑Ho Sun, Tae‑Hun Kim, Ki‑Yong Jung, You‑Kyung Choi, Eun Mee Lim, Yun‑Kyung Song, Jong‑Hyeong Park, Chan‑Yong Jun, Seong‑Gyu Ko
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Hydrogen sulfide suppresses angiotensin II-stimulated endothelin-1 generation and subsequent cytotoxicity-induced endoplasmic reticulum stress in endothelial cells via NF-κB

Heng‑Jing Hu, Zhi‑Sheng Jiang, Sheng‑Hua Zhou, Qi‑Ming Liu
Pages: 4729-4740
Published online on: 12 October 2016

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Differential expression of multidrug resistance‑related proteins in adriamycin‑resistant (pumc‑91/ADM) and parental (pumc‑91) human bladder cancer cell lines

Man Zhao, Shuliang Yu, Man Zhang
Pages: 4741-4746
Published online on: 05 October 2016

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Zoledronate induces autophagic cell death in human umbilical vein endothelial cells via Beclin-1 dependent pathway activation

Yong Lu, Zhiyong Wang, Wei Han, Hao Li
Pages: 4747-4754
Published online on: 12 October 2016

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Reduction of dynamin 1 in the hippocampus of aged mice is associated with the decline in hippocampal‑dependent memory

Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Hee Sun Yim, Dae Won Kim, Hajin Nam, Jun Gyo Suh, Jung Hoon Choi, Moo‑Ho Won, Yeo Sung Yoon, In Koo Hwang
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Alterations in the expression of Hs1-associated protein X-1 in the rat retina after optic nerve crush

Ling Cui, Wen‑Jing He, Fan Xu, Li Jiang, Ming‑Liang Lv, Hui Huang, Ji‑Ping Xu, Yu Wu, Hai‑Bin Zhong, Shao‑Yang Zhang, Li‑Fei Chen, Chao‑Lan Shen, Gang Yao, Li Li, Min Li, Si‑Ming Zeng
Pages: 4761-4766
Published online on: 11 October 2016

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Fructus Ligustri Lucidi ethanol extract inhibits osteoclastogenesis in RAW264.7 cells via the RANKL signaling pathway

Dan Xu, Ying Lyu, Xiaowen Chen, Xiaoyu Zhu, Jinqiu Feng, Yajun Xu
Pages: 4767-4774
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Suppression of GRASP65 phosphorylation by tetrahydrocurcumin protects against cerebral ischemia/reperfusion injury via ERK signaling

Bin Lin, Heng Yu, Yuting Lin, Chao Cai, Huoquan Lu, Xinbo Zhu
Pages: 4775-4780
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Lenalidomide induces apoptosis and inhibits angiogenesis via caspase‑3 and VEGF in hepatocellular carcinoma cells

Zhen Qu, Chunping Jiang, Junhua Wu, Yitao Ding
Pages: 4781-4786
Published online on: 05 October 2016

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Article

Ginkgolide B enhances the differentiation of preosteoblastic MC3T3-E1 cells through VEGF: Involvement of the p38 MAPK signaling pathway

Jiaquan Luo, Yu Zhong, Sheng Huang, Liangping Li, Chi Zhang, Xuenong Zou
Pages: 4787-4794
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miR-203 inhibits cell growth and regulates G1/S transition by targeting Bmi-1 in myeloma cells

Shun‑Quan Wu, Wen‑Yan Niu, Ya‑Ping Li, Hao‑Bo Huang, Rong Zhan
Pages: 4795-4801
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Biological characterization of three immortalized esophageal epithelial cell lines

Fa‑Min Zeng, Yang‑Min Xie, Lian‑Di Liao, Li‑Yan Li, Bo Chen, Jian‑Jun Xie, Li‑Yan Xu, En‑Min Li
Pages: 4802-4810
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RGR variants in different forms of retinal diseases: The undetermined role of truncation mutations

Jiali Li, Xueshan Xiao, Shiqiang Li, Xiaoyun Jia, Xiangming Guo, Qingjiong Zhang
Pages: 4811-4815
Published online on: 13 October 2016

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Mimotope identification of dust mite allergen Der f 5 using phage‑displayed random peptide libraries

Yubao Cui, Lili Yu, Ying Zhou, Li Yang, Chengbo Zhang
Pages: 4816-4822
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Proteins associated with EGFR-TKIs resistance in patients with non-small cell lung cancer revealed by mass spectrometry

Shaoyu Yang, Xueqin Chen, Yuelong Pan, Jiekai Yu, Xin Li, Shenglin Ma
Pages: 4823-4829
Published online on: 11 October 2016

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Endothelial‑like cells differentiated from mesenchymal stem cells attenuate neointimal hyperplasia after vascular injury

Jianzhong Xu, Duojiao Wu, Yan Yang, Kaida Ji, Pingjin Gao
Pages: 4830-4836
Published online on: 05 October 2016

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Article

Interleukin‑33‑induced immune tolerance is associated with the imbalance of memory and naïve T‑lymphocyte subsets

Xu Shi, Ying Tang, Xiguang Sun, Yufei Liu, Ying Sun, Munan Sun, Yanfang Jiang, Yulin Li
Pages: 4837-4843
Published online on: 13 October 2016

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Identification of therapeutic targets for Alzheimer's disease via differentially expressed gene and weighted gene co-expression network analyses

Yujie Jia, Kun Nie, Jing Li, Xinyue Liang, Xuezhu Zhang
Pages: 4844-4848
Published online on: 12 October 2016

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Protective and anti‑angiopathy effects of ginsenoside Re against diabetes mellitus via the activation of p38 MAPK, ERK1/2 and JNK signaling

Yawei Shi, Xuesi Wan, Nan Shao, Runyi Ye, Ning Zhang, Yunjian Zhang
Pages: 4849-4856
Published online on: 11 October 2016

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Antioxidant and immunostimulatory activities of polysaccharides extracted from Tremella aurantialba mycelia

Chao Deng, Yuanyuan Sun, Haitian Fu, Sixiu Zhang, Jinghua Chen, Xin Xu
Pages: 4857-4864
Published online on: 04 October 2016

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Antidiabetic activities of a cucurbitane‑type triterpenoid compound from Momordica charantia in alloxan‑induced diabetic mice

Bowen Jiang, Mingli Ji, Wei Liu, Lili Chen, Zhiyu Cai, Yuqing Zhao, Xiuli Bi
Pages: 4865-4872
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Article

Neurotoxin β‑N‑methylamino‑L‑alanine induces endoplasmic reticulum stress‑mediated neuronal apoptosis Corrigendum in /10.3892/mmr.2018.9242

Haiying Shen, Kiyoon Kim, Yoojung Oh, Kyung Sik Yoon, Hyung Hwan Baik, Sung Soo Kim, Joohun Ha, Insug Kang, Wonchae Choe
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Published online on: 05 October 2016

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Article

Protective effect of Pyropia yezoensis glycoprotein on chronic ethanol consumption-induced hepatotoxicity in rats

Jeong‑Wook Choi, In‑Hye Kim, Young‑Min Kim, Min‑Kyeong Lee, Youn‑Hee Choi, Taek‑Jeong Nam
Pages: 4881-4886
Published online on: 11 October 2016

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Article

Tc‑99m Ser‑Asp‑Val‑Glu‑Cys‑Gly: A novel Tc‑99m labeled hexapeptide for molecular and non‑invasive tumor imaging

Dae‑Weung Kim, Myoung Hyoun Kim, Chang Guhn Kim
Pages: 4887-4892
Published online on: 06 October 2016

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Article

Gap junction composed of connexin43 modulates 5‑fluorouracil, oxaliplatin and irinotecan resistance on colorectal cancers

Zhao‑Wei Zou, Hai‑Jin Chen, Jin‑Long Yu, Zong‑Hai Huang, Shun Fang, Xiao‑Hua Lin
Pages: 4893-4900
Published online on: 06 October 2016

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Article

Decreased expression of miR‑9 due to E50K OPTN mutation causes disruption of the expression of BDNF leading to RGC‑5 cell apoptosis

Bo Jiang, Lin Gao, Dawei Lei, Jiannan Liu, Zhengbo Shao, Xinrong Zhou, Renke Li, Donglai Wu, Fei Xue, Yuanmao Zhu, Huiping Yuan
Pages: 4901-4905
Published online on: 06 October 2016

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Exon 10 skipping in ACAT1 caused by a novel c.949G>A mutation located at an exonic splice enhancer site

Hiroki Otsuka, Hideo Sasai, Mina Nakama, Yuka Aoyama, Elsayed Abdelkreem, Hidenori Ohnishi, Vassiliki Konstantopoulou, Jörn Oliver Sass, Toshiyuki Fukao
Pages: 4906-4910
Published online on: 10 October 2016

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Exogenous hydrogen sulfide protects against high glucose‑induced inflammation and cytotoxicity in H9c2 cardiac cells

Zena Huang, Xiaobian Dong, Xiaodong Zhuang, Xun Hu, Lichun Wang, Xinxue Liao
Pages: 4911-4917
Published online on: 13 October 2016

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Clinical characteristics and the identification of novel mutations of COL1A1 and COL1A2 in 61 Chinese patients with osteogenesis imperfecta Corrigendum in /10.3892/mmr.2016.6095

Hao Zhang, Hua Yue, Chun Wang, Weiwei Hu, Jiemei Gu, Jinwei He, Wenzhen Fu, Yunqiu Hu, Miao Li, Zhenlin Zhang
Pages: 4918-4926
Published online on: 12 October 2016

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August-2026 Volume 34 Issue 2

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Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

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SCImago Journal Rank (SJR): 0.841

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[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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