|
1
|
Prantera C and Marconi S:
Glucocorticosteroids in the treatment of inflammatory bowel disease
and approaches to minimizing systemic activity. Therap Adv
Gastroenterol. 6:137–156. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Cosnes J, Gower-Rousseau C, Seksik P and
Cortot A: Epidemiology and natural history of inflammatory bowel
diseases. Gastroenterology. 140:1785–1794. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Podolsky DK: Inflammatory bowel disease. N
Engl J Med. 347:417–429. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Podolsky DK: The current future
understanding of inflammatory bowel disease. Best Pract Res Clin
Gastroenterol. 16:933–943. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Carter MJ, Lobo AJ and Travis SP: IBD
Section, British Society of Gastroenterology: Guidelines for the
management of inflammatory bowel disease in adults. Gut 53 Suppl.
5:V1–V16. 2004. View Article : Google Scholar
|
|
6
|
Danese S and Fiocchi C: Etiopathogenesis
of inflammatory bowel diseases. World J Gastroenterol.
12:4807–4812. 2006.PubMed/NCBI
|
|
7
|
Nunes T, Fiorino G, Danese S and Sans M:
Familial aggregation in inflammatory bowel disease: Is it genes or
environment? World J Gastroenterol. 17:2715–2722. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
El-Salhy M, Gundersen D, Hatlebakk JG and
Hausken T: Clinical presentation, diagnosis, pathogenesis and
treatment options for lymphocytic colitis (Review). Int J Mol Med.
32:263–270. 2013.PubMed/NCBI
|
|
9
|
El-Salhy M, Seim I, Chopin L, Gundersen D,
Hatlebakk JG and Hausken T: Irritable bowel syndrome: The role of
gut neuroendocrine peptides. Front Biosci (Elite Ed). 4:2783–2800.
2012.PubMed/NCBI
|
|
10
|
El-Salhy M, Gundersen D, Hatlebakk JG and
Hausken T: Irritable bowel syndrome: Diagnosis, pathogenesis, and
treatment options. Nova Science Publishers, Inc., New York;
2012
|
|
11
|
El-Salhy M: Irritable bowel syndrome:
Diagnosis and pathogenesis. World J Gastroenterol. 18:5151–5163.
2012.PubMed/NCBI
|
|
12
|
El-Salhy M, Ostgaard H, Gundersen D,
Hatlebakk JG and Hausken T: The role of diet in the pathogenesis
and management of irritable bowel syndrome (Review). Int J Mol Med.
29:723–731. 2012.PubMed/NCBI
|
|
13
|
Mawe GM, Coates MD and Moses PL: Review
article: Intestinal serotonin signalling in irritable bowel
syndrome. Aliment Pharmacol Ther. 23:1067–1076. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wade PR, Chen J, Jaffe B, Kassem IS,
Blakely RD and Gershon MD: Localization and function of a 5-HT
transporter in crypt epithelia of the gastrointestinal tract. J
Neurosci. 16:2352–2364. 1996.PubMed/NCBI
|
|
15
|
Gershon MD and Tack J: The serotonin
signaling system: From basic understanding to drug development for
functional GI disorders. Gastroenterology. 132:397–414. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gershon MD: 5-Hydroxytryptamine
(serotonin) in the gastrointestinal tract. Curr Opin Endocrinol
Diabetes Obes. 20:14–21. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Gershon MD: Serotonin is a sword and a
shield of the bowel: Serotonin plays offense and defense. Trans Am
Clin Climatol Assoc. 123:268–280. 2012.PubMed/NCBI
|
|
18
|
El-Salhy M, Mazzawi T, Gundersen D,
Hatlebakk JG and Hausken T: The role of peptide YY in
gastrointestinal diseases and disorders (review). Int J Mol Med.
31:275–282. 2013.PubMed/NCBI
|
|
19
|
Dubrasquet M, Bataille D and Gespach C:
Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): A potent
inhibitor of pentagastrin-stimulated acid secretion in rats. Biosci
Rep. 2:391–395. 1982. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Schjoldager B, Mortensen PE, Myhre J,
Christiansen J and Holst JJ: Oxyntomodulin from distal gut. Role in
regulation of gastric and pancreatic functions. Dig Dis Sci.
34:1411–1419. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Schjoldager BT, Baldissera FG, Mortensen
PE, Holst JJ and Christiansen J: Oxyntomodulin: A potential hormone
from the distal gut. Pharmacokinetics and effects on gastric acid
and insulin secretion in man. Eur J Clin Invest. 18:499–503. 1988.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Dakin CL, Small CJ, Batterham RL, Neary
NM, Cohen MA, Patterson M, Ghatei MA and Bloom SR: Peripheral
oxyntomodulin reduces food intake and body weight gain in rats.
Endocrinology. 145:2687–2695. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wynne K, Park AJ, Small CJ, Patterson M,
Ellis SM, Murphy KG, Wren AM, Frost GS, Meeran K, Ghatei MA and
Bloom SR: Subcutaneous oxyntomodulin reduces body weight in
overweight and obese subjects: A double-blind, randomized,
controlled trial. Diabetes. 54:2390–2395. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
El-Salhy M and Hausken T: The role of the
neuropeptide Y (NPY) family in the pathophysiology of inflammatory
bowel disease (IBD). Neuropeptides. 55:134–144. 2016. View Article : Google Scholar
|
|
25
|
Camilleri M: Peripheral mechanisms in
irritable bowel syndrome. N Engl J Med. 367:1626–1635. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Jianu CS, Fossmark R, Syversen U, Hauso Ø
and Waldum HL: A meal test improves the specificity of chromogranin
A as a marker of neuroendocrine neoplasia. Tumour Biol. 31:373–380.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
El-Salhy M, Danielsson A, Stenling R and
Grimelius L: Colonic endocrine cells in inflammatory bowel disease.
J Intern Med. 242:413–419. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
El-Salhy M, Gundersen D, Hatlebakk JG and
Hausken T: Chromogranin a cell density as a diagnostic marker for
lymphocytic colitis. Dig Dis Sci. 57:3154–3159. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
El-Salhy M, Gundersen D, Hatlebakk JG and
Hausken T: High densities of serotonin and peptide YY cells in the
colon of patients with lymphocytic colitis. World J Gastroenterol.
18:6070–6075. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
El-Salhy M, Lomholt-Beck B and Gundersen
TD: High chromogranin A cell density in the colon of patients with
lymphocytic colitis. Mol Med Rep. 4:603–605. 2011.PubMed/NCBI
|
|
31
|
Moran GW, Pennock J and McLaughlin JT:
Enteroendocrine cells in terminal ileal Crohn's disease. J Crohns
Colitis. 6:871–880. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Besterman HS, Mallinson CN, Modigliani R,
Christofides ND, Pera A, Ponti V, Sarson DL and Bloom SR: Gut
hormones in inflammatory bowel disease. Scand J Gastroenterol.
18:845–852. 1983. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
El-Salhy M, Suhr O and Danielsson A:
Peptide YY in gastrointestinal disorders. Peptides. 23:397–402.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tari A, Teshima H, Sumii K, Haruma K,
Ohgoshi H, Yoshihara M, Kajiyama G and Miyachi Y: Peptide YY
abnormalities in patients with ulcerative colitis. Jpn J Med.
27:49–55. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Sciola V, Massironi S, Conte D, Caprioli
F, Ferrero S, Ciafardini C, Peracchi M, Bardella MT and Piodi L:
Plasma chromogranin a in patients with inflammatory bowel disease.
Inflamm Bowel Dis. 15:867–871. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Bishop AE, Pietroletti R, Taat CW,
Brummelkamp WH and Polak JM: Increased populations of endocrine
cells in Crohn's ileitis. Virchows Arch A Pathol Anat Histopathol.
410:391–396. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Manocha M and Khan WI: Serotonin and GI
disorders: An update on clinical and experimental studies. Clin
Transl Gastroenterol. 3:e132012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Stoyanova II and Gulubova MV: Mast cells
and inflammatory mediators in chronic ulcerative colitis. Acta
Histochem. 104:185–192. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yamamoto H, Morise K, Kusugami K, Furusawa
A, Konagaya T, Nishio Y, Kaneko H, Uchida K, Nagai H, Mitsuma T and
Nagura H: Abnormal neuropeptide concentration in rectal mucosa of
patients with inflammatory bowel disease. J Gastroenterol.
31:525–532. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Payer J, Huorka M, Duris I, Mikulecky M,
Kratochvílová H, Ondrejka P and Lukác L: Plasma somatostatin levels
in ulcerative colitis. Hepatogastroenterology. 41:552–553.
1994.PubMed/NCBI
|
|
41
|
Watanabe T, Kubota Y, Sawada T and Muto T:
Distribution and quantification of somatostatin in inflammatory
disease. Dis Colon Rectum. 35:488–494. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Koch TR, Carney JA, Morris VA and Go VL:
Somatostatin in the idiopathic inflammatory bowel diseases. Dis
Colon Rectum. 31:198–203. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Khan WI and Ghia JE: Gut hormones:
Emerging role in immune activation and inflammation. Clin Exp
Immunol. 161:19–27. 2010.PubMed/NCBI
|
|
44
|
Margolis KG and Gershon MD: Neuropeptides
and inflammatory bowel disease. Curr Opin Gastroenterol.
25:503–511. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Bampton PA and Dinning PG: High resolution
colonic manometry-what have we learnt?-A review of the literature
2012. Curr Gastroenterol Rep. 15:3282013. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Wang J, Cortina G, Wu SV, Tran R, Cho JH,
Tsai MJ, Bailey TJ, Jamrich M, Ament ME, Treem WR, et al: Mutant
neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med.
355:270–280. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
El-Salhy M and Umezawa K: Treatment with
novel AP-1 and NF-κB inhibitors restores the colonic endocrine
cells to normal levels in rats with DSS-induced colitis. Int J Mol
Med. 37:556–564. 2016.PubMed/NCBI
|
|
48
|
Funakoshi T, Yamashita K, Ichikawa N,
Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T,
Ichihara S, et al: A novel NF-kappaB inhibitor,
dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic
injury in mice. J Crohns Colitis. 6:215–225. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
El-Salhy M, Umezawa K, Gilja OH, Hatlebakk
JG, Gundersen D and Hausken T: Amelioration of severe TNBS induced
colitis by novel AP-1 and NF-κB inhibitors in rats. Scientific
World Journal. 2014:8138042014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Grimstad T, Bjørndal B, Cacabelos D,
Aasprong OG, Omdal R, Svardal A, Bohov P, Pamplona R, Portero-Otin
M, Berge RK and Hausken T: A salmon peptide diet alleviates
experimental colitis as compared with fish oil. J Nutr Sci.
2:e22013. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Stucchi AF, Shofer S, Leeman S, Materne O,
Beer E, McClung J, Shebani K, Moore F, O'Brien M and Becker JM:
NK-1 antagonist reduces colonic inflammation and oxidative stress
in dextran sulfate-induced colitis in rats. Am J Physiol
Gastrointest Liver Physiol. 279:G1298–G1306. 2000.PubMed/NCBI
|
|
52
|
Ota E, Takeiri M, Tachibana M, Ishikawa Y,
Umezawa K and Nishiyama S: Synthesis and biological evaluation of
molecular probes based on the 9-methylstreptimidone derivative
DTCM-glutarimide. Bioorg Med Chem Lett. 22:164–167. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Takeiri M, Tachibana M, Kaneda A, Ito A,
Ishikawa Y, Nishiyama S, Goto R, Yamashita K, Shibasaki S, Hirokata
G, et al: Inhibition of macrophage activation and suppression of
graft rejection by DTCM-glutarimide, a novel piperidine derived
from the antibiotic 9-methylstreptimidone. Inflamm Res. 60:879–888.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Ishikawa Y, Tachibana M, Matsui C, Obata
R, Umezawa K and Nishiyama S: Synthesis and biological evaluation
on novel analogs of 9-methylstreptimidone, an inhibitor of
NF-kappaB. Bioorg Med Chem Lett. 19:1726–1728. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Umezawa N, Matsumoto N, Iwama S, Kato N
and Higuchi T: Facile synthesis of peptide-porphyrin conjugates:
Towards artificial catalase. Bioorg Med Chem. 18:6340–6350. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
el-Salhy M, Sandstrom O, Näsström E,
Mustajbasic M and Zachrisson S: Application of computer image
analysis in endocrine cell quantification. Histochem J. 29:249–256.
1997. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
El-Salhy M, Gilja OH, Gundersen D,
Hatlebakk JG and Hausken T: Duodenal chromogranin a cell density as
a biomarker for the diagnosis of irritable bowel syndrome.
Gastroenterol Res Pract. 2014:4628562014. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Elson CO, Sartor RB, Tennyson GS and
Riddell RH: Experimental models of inflammatory bowel disease.
Gastroenterology. 109:1344–1367. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Cardoso WV and Lü J: Regulation of early
lung morphogenesis: Questions, facts and controversies.
Development. 133:1611–1624. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Darlington GJ: Molecular mechanisms of
liver development and differentiation. Curr Opin Cell Biol.
11:678–682. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Fausto N, Campbell JS and Riehle KJ: Liver
regeneration. Hepatology. 43(2 Suppl 1): S45–S53. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Rawlins EL and Hogan BL: Ciliated
epithelial cell lifespan in the mouse trachea and lung. Am J
Physiol Lung Cell Mol Physiol. 295:L231–L234. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Zaret KS: Regulatory phases of early liver
development: Paradigms of organogenesis. Nat Rev Genet. 3:499–512.
2002. View
Article : Google Scholar : PubMed/NCBI
|
|
64
|
Barker N, van Es JH, Kuipers J, Kujala P,
van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H,
Peters PJ and Clevers H: Identification of stem cells in small
intestine and colon by marker gene Lgr5. Nature. 449:1003–1007.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Barker N, van de Wetering M and Clevers H:
The intestinal stem cell. Genes Dev. 22:1856–1864. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Cheng H and Leblond CP: Origin,
differentiation and renewal of the four main epithelial cell types
in the mouse small intestine. V. Unitarian theory of the origin of
the four epithelial cell types. Am J Anat. 141:537–561. 1974.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Le Douarin NM and Teillet MA: The
migration of neural crest cells to the wall of the digestive tract
in avian embryo. J Embryol Exp Morphol. 30:31–48. 1973.PubMed/NCBI
|
|
68
|
Rawdon BB and Andrew A: Origin and
differentiation of gut endocrine cells. Histol Histopathol.
8:567–580. 1993.PubMed/NCBI
|
|
69
|
Hoffman J, Kuhnert F, Davis CR and Kuo CJ:
Wnts as essential growth factors for the adult small intestine and
colon. Cell Cycle. 3:554–557. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Korinek V, Barker N, Moerer P, van
Donselaar E, Huls G, Peters PJ and Clevers H: Depletion of
epithelial stem-cell compartments in the small intestine of mice
lacking Tcf-4. Nat Genet. 19:379–383. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Montgomery RK and Breault DT: Small
intestinal stem cell markers. J Anat. 213:52–58. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Potten CS, Booth C, Tudor GL, Booth D,
Brady G, Hurley P, Ashton G, Clarke R, Sakakibara S and Okano H:
Identification of a putative intestinal stem cell and early lineage
marker; musashi-1. Differentiation. 71:28–41. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Kayahara T, Sawada M, Takaishi S, Fukui H,
Seno H, Fukuzawa H, Suzuki K, Hiai H, Kageyama R, Okano H and Chiba
T: Candidate markers for stem and early progenitor cells, Musashi-1
and Hes1, are expressed in crypt base columnar cells of mouse small
intestine. FEBS Lett. 535:131–135. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
He XC, Yin T, Grindley JC, Tian Q, Sato T,
Tao WA, Dirisina R, Porter-Westpfahl KS, Hembree M, Johnson T, et
al: PTEN-deficient intestinal stem cells initiate intestinal
polyposis. Nat Genet. 39:189–198. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Yang Q, Bermingham NA, Finegold MJ and
Zoghbi HY: Requirement of Math1 for secretory cell lineage
commitment in the mouse intestine. Science. 294:2155–2158. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Jenny M, Uhl C, Roche C, Duluc I,
Guillermin V, Guillemot F, Jensen J, Kedinger M and Gradwohl G:
Neurogenin3 is differentially required for endocrine cell fate
specification in the intestinal and gastric epithelium. EMBO J.
21:6338–6347. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Lee CS, Perreault N, Brestelli JE and
Kaestner KH: Neurogenin 3 is essential for the proper specification
of gastric enteroendocrine cells and the maintenance of gastric
epithelial cell identity. Genes Dev. 16:1488–1497. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo
FJ, Leiter AB and Tsai MJ: Diabetes, defective pancreatic
morphogenesis and abnormal enteroendocrine differentiation in
BETA2/neuroD-deficient mice. Genes Dev. 11:2323–2334. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Ahlgren U, Jonsson J and Edlund H: The
morphogenesis of the pancreatic mesenchyme is uncoupled from that
of the pancreatic epithelium in IPF1/PDX1-deficient mice.
Development. 122:1409–1416. 1996.PubMed/NCBI
|
|
80
|
Schonhoff SE, Giel-Moloney M and Leiter
AB: Minireview: Development and differentiation of gut endocrine
cells. Endocrinology. 145:2639–2644. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Yang G, Bibi S, Du M, Suzuki T and Zhu MJ:
Regulation of the intestinal tight junction by natural polyphenols:
A mechanistic perspective. Crit Rev Food Sci Nutr. Mar
23–2016.(Epub ahead of print). View Article : Google Scholar
|
|
82
|
Yang G, Wang H, Kang Y and Zhu MJ: Grape
seed extract improves epithelial structure and suppresses
inflammation in ileum of IL-10-deficient mice. Food Funct.
5:2558–2563. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Yang G, Xue Y, Zhang H, Du M and Zhu MJ:
Favourable effects of grape seed extract on intestinal epithelial
differentiation and barrier function in IL10-deficient mice. Br J
Nutr. 114:15–23. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Yang GB and Lackner AA: Proximity between
5-HT secreting enteroendocrine cells and lymphocytes in the gut
mucosa of rhesus macaques (Macaca mulatta) is suggestive of a role
for enterochromaffin cell 5-HT in mucosal immunity. J Neuroimmunol.
146:46–49. 2004. View Article : Google Scholar : PubMed/NCBI
|
