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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2017 Volume 15 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Non‑coding RNAs and ovarian diseases (Review)

Dandan Li, Duo Xu, Yinggang Zou, Ying Xu, Lulu Fu, Xin Xu, Yongzheng Liu, Xueying Zhang, Jingshun Zhang, Hao Ming, Lianwen Zheng
Pages: 1435-1440
Published online on: 08 February 2017

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Article Open Access

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis

Feng‑Tao Shi, Mei Yu, David Zloty, Robert H. Bell, Eddy Wang, Noushin Akhoundsadegh, Gigi Leung, Anne Haegert, Nicholas Carr, Jerry Shapiro, Kevin J. McElwee
Pages: 1441-1454
Published online on: 02 February 2017

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Article Open Access

Increased Δ133p53 mRNA in lung carcinoma corresponds with reduction of p21 expression

Aikaterini Fragou, Georgios Tzimagiorgis, Christos Karageorgopoulos, Nikolaos Barbetakis, Axilleas Lazopoulos, Maria Papaioannou, Costas Haitoglou, Sofia Kouidou
Pages: 1455-1460
Published online on: 02 February 2017

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Article Open Access

Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer

Sheng Chen, Ye Wang, Wen‑Long Zhang, Mao‑Sheng Dong, Jian‑Hua Zhang
Pages: 1461-1470
Published online on: 08 February 2017

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Article Open Access

An improved method for the establishment of a model of Graves' disease in BALB/c mice

Wei Zheng, Renfei Wang, Jian Tan, Ning Li, Zhaowei Meng
Pages: 1471-1478
Published online on: 08 February 2017

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Article Open Access

The involvement of Eag1 potassium channels and miR-34a in rotenone-induced death of dopaminergic SH-SY5Y cells

Camila Hillesheim Horst, Ricardo Titze‑de‑Almeida, Simoneide Souza Titze‑de‑Almeida
Pages: 1479-1488
Published online on: 10 February 2017

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Article Open Access

MicroRNA‑185 regulates transforming growth factor‑β1 and collagen‑1 in hypertrophic scar fibroblasts

Kaiyan Xiao, Xusong Luo, Xiuxia Wang, Zhen Gao
Pages: 1489-1496
Published online on: 08 February 2017

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Article Open Access

Intermedin1‑53 enhances angiogenesis and attenuates adverse remodeling following myocardial infarction by activating AMP‑activated protein kinase

Kankai Chen, Meiling Yan, Yongguang Li, Zhifeng Dong, Dong Huang, Jingbo Li, Meng Wei
Pages: 1497-1506
Published online on: 10 February 2017

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Article Open Access

Expression of cyclooxygenase-2 is correlated with lncRNA-COX-2 in cirrhotic mice induced by carbon tetrachloride

Shi‑Hang Tang, Jin‑Hang Gao, Shi‑Lei Wen, Huan Tong, Zhao‑Ping Yan, Rui Liu, Cheng‑Wei Tang
Pages: 1507-1512
Published online on: 02 February 2017

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Article Open Access

Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia

Betty Kalikstad, Hanna Göransson Kultima, Terese Kristoffersen Andersstuen, Arne Klungland, Anders Isaksson
Pages: 1513-1526
Published online on: 08 February 2017

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Article Open Access

Overexpression of KAI1/CD82 suppresses in vitro cell growth, migration, invasion and xenograft growth in oral cancer

Juan Chai, Liangzhi Du, Jun Ju, Chao Ma, Zhiyuan Shen, Xiangming Yang, Liang Liang, Qianwei Ni, Moyi Sun
Pages: 1527-1532
Published online on: 09 February 2017

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Article Open Access

Comparative investigation of the effects of specific antigen‑sensitized DC‑CIK and DC‑CTL cells against B16 melanoma tumor cells

Peng‑Tao Ren, Yuan Zhang
Pages: 1533-1538
Published online on: 07 February 2017

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Article Open Access

Estrogen stimulates osteoprotegerin expression via the suppression of miR-145 expression in MG-63 cells

Jun Jia, Hengxing Zhou, Xiantie Zeng, Shiqing Feng
Pages: 1539-1546
Published online on: 06 February 2017

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Article Open Access

Expression of mmu-miR-96 in the endometrium during early pregnancy and its regulatory effects on stromal cell apoptosis via Bcl2

Yuan Yang, Yi Xie, Mengyun Wu, Yanqing Geng, Rong Li, Lei Xu, Xueqing Liu, Yongquan Pan
Pages: 1547-1554
Published online on: 17 February 2017

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Article Open Access

γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function

Changli Tao, Hongwei Shao, Wenfeng Zhang, Huaben Bo, Fenglin Wu, Han Shen, Shulin Huang
Pages: 1555-1564
Published online on: 15 February 2017

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Article Open Access

Inhibition of triggering receptor expressed on myeloid cells-1 ameliorates experimental autoimmune neuritis

Xiaoliang Zhou, Yanli Wang, Yuzhong Wang, Peter Cipriano, Bo Xiao, Wenbin Zhou
Pages: 1565-1570
Published online on: 06 February 2017

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Article Open Access

Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes

Xiaoyuan Xu, He Jiang, Xingnuan Li, Ping Wu, Jianyun Liu, Tao Wang, Xiaoou Zhou, Jianjun Xiong, Weidong Li
Pages: 1571-1576
Published online on: 08 February 2017

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Article Open Access

Identification of key genes and pathways associated with spinal cord injury

Yue‑Hui Zhang, Jia Song, Li‑Gang Wang, Jiang Shao
Pages: 1577-1584
Published online on: 10 February 2017

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Article Open Access

Inhibitory effects of vitamin E on osteocyte apoptosis and DNA oxidative damage in bone marrow hemopoietic cells at early stage of steroid-induced femoral head necrosis

Yan‑Bo Jia, Dian‑Ming Jiang, Yi‑Zhong Ren, Zi‑Hong Liang, Zhen‑Qun Zhao, Yu‑Xin Wang
Pages: 1585-1592
Published online on: 02 February 2017

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Article Open Access

Construction and verification of CYP3A5 gene polymorphisms using a Saccharomyces cerevisiae expression system to predict drug metabolism

Yao Lu, Hua Zhong, Qing Tang, Zhijun Huang, Ningning Jing, Julie Smith, Rujia Miao, Yapei Li, Hong Yuan
Pages: 1593-1600
Published online on: 17 February 2017

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Article Open Access

Spatiotemporal expression of Wnt3a during striated muscle complex development in rat embryos with ethylenethiourea-induced anorectal malformations

Yuanyuan Geng, Jie Mi, Hong Gao, Huimin Jia, Weilin Wang
Pages: 1601-1606
Published online on: 15 February 2017

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Article Open Access

The tripartite motif-containing protein 3 on the proliferation and cytokine secretion of rheumatoid arthritis fibroblast-like synoviocytes

Mingjun Wang, Jian Wu, Yufan Guo, Xin Chang, Tao Cheng
Pages: 1607-1612
Published online on: 02 February 2017

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Article Open Access

Ethyl acetate extract from Asparagus cochinchinensis exerts anti‑inflammatory effects in LPS‑stimulated RAW264.7 macrophage cells by regulating COX‑2/iNOS, inflammatory cytokine expression, MAP kinase pathways, the cell cycle and anti-oxidant activity

Hyun Ah Lee, Eun Kyoung Koh, Ji Eun Sung, Ji Eun Kim, Sung Hwa Song, Dong Seob Kim, Hong Joo Son, Chung Yeoul Lee, Hee Seob Lee, Chang Joon Bae, Dae Youn Hwang
Pages: 1613-1623
Published online on: 03 February 2017

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Article Open Access

Thin magnesium layer confirmed as an antibacterial and biocompatible implant coating in a co‑culture model

Sarah Zaatreh, David Haffner, Madlen Strauss, Thomas Dauben, Christiane Zamponi, Wolfram Mittelmeier, Eckhard Quandt, Bernd Kreikemeyer, Rainer Bader
Pages: 1624-1630
Published online on: 17 February 2017

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Article Open Access

miR-34a is downregulated in human osteosarcoma stem-like cells and promotes invasion, tumorigenic ability and self-renewal capacity Retraction in /10.3892/mmr.2024.13196

Yonggen Zou, Yuanshuai Huang, Jiexiang Yang, Jian Wu, Cheng Luo
Pages: 1631-1637
Published online on: 09 February 2017

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Article Open Access

Reduced expression of SIRT2 in serous ovarian carcinoma promotes cell proliferation through disinhibition of CDK4 expression

Yanhua Du, Jun Wu, Haiyan Zhang, Shaobo Li, Hong Sun
Pages: 1638-1646
Published online on: 08 February 2017

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Article Open Access

Low concentrations of bilirubin inhibit activation of hepatic stellate cells in vitro

Yinhe Tang, Qiyu Zhang, Yefan Zhu, Gang Chen, Fuxiang Yu
Pages: 1647-1653
Published online on: 14 February 2017

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Article Open Access

LATS1 suppresses proliferation and invasion of cervical cancer

Jihong Deng, Wen Zhang, Shuangyue Liu, Hongmei An, Lu Tan, Lisha Ma
Pages: 1654-1660
Published online on: 08 February 2017

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Article Open Access

Identification of prognostic genes in kidney renal clear cell carcinoma by RNA‑seq data analysis

Yanqin Gu, Linfeng Lu, Lingfeng Wu, Hao Chen, Wei Zhu, Yi He
Pages: 1661-1667
Published online on: 13 February 2017

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Article Open Access

A genetic risk factor for thrombophilia in a Han Chinese family

Guoping Sun, Yicong Jia, Jingye Meng, Minglin Ou, Peng Zhu, Shan Cong, Yadan Luo, Weiguo Sui, Yong Dai
Pages: 1668-1672
Published online on: 17 February 2017

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Article Open Access

Dickkopf-related protein 3 negatively regulates the osteogenic differentiation of rat dental follicle cells

Xinchun Zhang, Yu Du, Junqi Ling, Weiqiang Li, Yan Liao, Xi Wei
Pages: 1673-1681
Published online on: 03 February 2017

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Article Open Access

Signal transduction involved in lipoxin A4‑induced protection of tubular epithelial cells against hypoxia/reoxygenation injury

Sheng‑Hua Wu, Ming‑Jie Wang, Jing Lü, Xiao‑Qing Chen
Pages: 1682-1692
Published online on: 13 February 2017

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Article Open Access

Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells

Jinxi He, Juan Shi, Kangjian Zhang, Jing Xue, Jing Li, Jiali Yang, Juan Chen, Jun Wei, Hong Ren, Xiaoming Liu
Pages: 1693-1701
Published online on: 06 February 2017

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Article Open Access

Baicalin ameliorates renal fibrosis via inhibition of transforming growth factor β1 production and downstream signal transduction

Long Zheng, Chao Zhang, Long Li, Chao Hu, Mushuang Hu, Niyazi Sidikejiang, Xuanchuan Wang, Miao Lin, Ruiming Rong
Pages: 1702-1712
Published online on: 16 February 2017

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Article Open Access

CD164 regulates proliferation and apoptosis by targeting PTEN in human glioma

Ming Tu, Lin Cai, Weiming Zheng, Zhipeng Su, Yong Chen, Songtao Qi
Pages: 1713-1721
Published online on: 15 February 2017

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Article Open Access

Apoptosis‑independent cleavage of RhoGDIβ at Asp19 during PMA‑stimulated differentiation of THP‑1 cells to macrophages

Takahide Ota, Yong‑Sheng Jiang, Mamoru Fujiwara, Masaaki Tatsuka
Pages: 1722-1726
Published online on: 13 February 2017

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Article Open Access

Siamese crocodile bile induces apoptosis in NCI-H1299 human non-small cell lung cancer cells via a mitochondria-mediated intrinsic pathway and inhibits tumorigenesis

Ling Tian, Yi‑Tao Deng, Xin Dong, Jia‑Yi Fan, Hua‑Liang Li, Yu‑Mei Ding, Wei‑Xi Peng, Qing‑Xi Chen, Dong‑Yan Shen
Pages: 1727-1737
Published online on: 16 February 2017

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Article Open Access

Development of an assay to assess genotoxicity by particulate matter extract

Alexandros Priftis, Konstantinos Papikinos, Marina Koukoulanaki, Efthalia Kerasioti, Dimitrios Stagos, Konstantinos Konstantinopoulos, Demetrios A. Spandidos, Marianthi Kermenidou, Spyros Karakitsios, Dimosthenis Sarigiannis, Aristides M. Tsatsakis, Demetrios Kouretas
Pages: 1738-1746
Published online on: 06 February 2017

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Article

Curcumin inhibits hypoxia-induced proliferation and invasion of MG-63 osteosarcoma cells via downregulating Notch1

Zhan Wang, Kun Zhang, Yangjun Zhu, Dengfeng Wang, Yuxiong Shao, Jun Zhang
Pages: 1747-1752
Published online on: 30 January 2017

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Article

Tauroursodeoxycholic acid inhibits TNF-α-induced lipolysis in 3T3-L1 adipocytes via the IRE-JNK-perilipin-A signaling pathway

Wenyan Xia, Yu Zhou, Lijing Wang, Linxi Wang, Xiaoying Liu, Yichuan Lin, Qing Zhou, Jianqing Huang, Libin Liu
Pages: 1753-1758
Published online on: 16 February 2017

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Article

Activation‑induced upregulation of MMP9 in mast cells is a positive feedback mediator for mast cell activation

Lin Xu, Zhijian Cai, Fei Yang, Ming Chen
Pages: 1759-1764
Published online on: 17 February 2017

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Article

Astragaloside IV inhibits isoprenaline‑induced cardiac fibrosis by targeting the reactive oxygen species/mitogen‑activated protein kinase signaling axis

Hongliang Dai, Guizhi Jia, Meili Lu, Chunguang Liang, Yue Wang, Hongxin Wang
Pages: 1765-1770
Published online on: 17 February 2017

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Article

Effect of chloride channel activity on retinal pigment cell proliferation and migration

Jing Zhao, Wei Zhong, Lixia Sun, Yuan Yin, Yajuan Zheng
Pages: 1771-1776
Published online on: 14 February 2017

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Article

Reduced Klotho expression contributes to poor survival rates in human patients with ovarian cancer, and overexpression of Klotho inhibits the progression of ovarian cancer partly via the inhibition of systemic inflammation in nude mice

Youliang Yan, Yifeng Wang, Yi Xiong, Xiufeng Lin, Ping Zhou, Zhiying Chen
Pages: 1777-1785
Published online on: 07 February 2017

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Article

PPAR‑γ agonist rosiglitazone protects rat peritoneal mesothelial cells against peritoneal dialysis solution‑induced damage

Yun‑Fang Zhang, Qi Wang, Yan‑Yan Su, Jie‑Lin Wang, Bao‑Jun Hua, Shen Yang, Jun‑Xia Feng, Hong‑Yan Li
Pages: 1786-1792
Published online on: 13 February 2017

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Article

Increased β‑catenin and c-myc expression predict aggressive growth of non-functioning pituitary adenomas: An assessment using a tissue microarray-based approach

Chunhui Liu, Youtu Wu, Shengyuan Yu, Jiwei Bai, Chuzhong Li, Dan Wu, Yazhuo Zhang
Pages: 1793-1799
Published online on: 06 February 2017

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Article

Periostin is essential for periodontal ligament remodeling during orthodontic treatment

Hui‑Yong Xu, Er‑Min Nie, Gang Deng, Ling‑Zhi Lai, Feng‑Yang Sun, Hua Tian, Fu‑Chun Fang, Ya‑Guang Zou, Bu‑Ling Wu, Jun Ou‑Yang
Pages: 1800-1806
Published online on: 13 February 2017

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Article

Proteomic analysis of oridonin-induced apoptosis in multiple myeloma cells

Jing Zhao, Mei Zhang, Pengcheng He, Junjie Zhao, Ying Chen, Jun Qi, Yuan Wang
Pages: 1807-1815
Published online on: 17 February 2017

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Article

Photodynamic inactivation of fibroblasts and inhibition of Staphylococcus epidermidis adhesion and biofilm formation by toluidine blue O

Xin Li, Zizhong Liu, Houfang Liu, Xi Chen, Yue Liu, Honglue Tan
Pages: 1816-1822
Published online on: 08 February 2017

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Article

Role of gap junctions in the contractile response to agonists in the mesenteric resistance artery of rats with acute hypoxia

Huan Liu, Xin‑Zhi Li, Min Peng, Wei Ji, Lei Zhao, Li Li, Liang Zhang, Jun‑Qiang Si, Ke‑Tao Ma
Pages: 1823-1831
Published online on: 09 February 2017

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Article

Molecular characterization of mitochondrial transferRNAGln and transferRNAMet A4401G mutations in a Chinese family with hypertension

Shuai‑Shuai Yu, Ji‑Mei Du, Zhi‑De Tang, Zhi‑Feng He
Pages: 1832-1836
Published online on: 17 February 2017

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Article

Identification of miR‑30b as an oncogene in renal cell carcinoma

Lu Jin, Yifan Li, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Min Shi, Zhimao Jiang, Shangqi Yang, Xiangming Mao, Yaoting Gui, Yongqing Lai
Pages: 1837-1846
Published online on: 13 February 2017

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Article

Attenuation of prostaglandin E1‑induced osteoprotegerin synthesis in osteoblasts by normoxic HIF inducers

Gen Kuroyanagi, Haruhiko Tokuda, Naohiro Yamamoto, Shingo Kainuma, Kazuhiko Fujita, Reou Ohguchi, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Takanobu Otsuka
Pages: 1847-1852
Published online on: 08 February 2017

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Article

The expression and significance of HOX transcript antisense RNA and epithelial-mesenchymal transition-related factors in esophageal squamous cell carcinoma

Chunli Da, Yiyi Zhan, Yu Li, Yao Tan, Ruiguang Li, Ruozheng Wang
Pages: 1853-1862
Published online on: 16 February 2017

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Article

Sevoflurane downregulates IGF‑1 via microRNA‑98

Jue Jiang, Zhifeng Chen, Yaqiong Yang, Jia Yan, Hong Jiang
Pages: 1863-1868
Published online on: 17 February 2017

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Article

Glycometabolic adaptation mediates the insensitivity of drug-resistant K562/ADM leukaemia cells to adriamycin via the AKT-mTOR/c-Myc signalling pathway

Xueyan Zhang, Ziying Ai, Jing Chen, Juan Yi, Zhuan Liu, Huaishun Zhao, Hulai Wei
Pages: 1869-1876
Published online on: 10 February 2017

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Article

EBV‑BART‑6‑3p and cellular microRNA‑197 compromise the immune defense of host cells in EBV‑positive Burkitt lymphoma

Yang‑Min Zhang, Yan Yu, He‑Ping Zhao
Pages: 1877-1883
Published online on: 07 February 2017

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Article

Overexpression of miR‑214 promotes the progression of human osteosarcoma by regulating the Wnt/β‑catenin signaling pathway

Xun‑Bing Zhu, Zhong‑Chuan Zhang, Guan‑Sheng Han, Jun‑Zhu Han, Da‑Peng Qiu
Pages: 1884-1892
Published online on: 14 February 2017

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Article

Synergistic antinociceptive effects of alfentanil and propofol in the formalin test

Na Jia, Xiaochun Zuo, Chao Guo, Yuwen Li, Jia Cui, Chao Zhao, Shanshan Cao, Chao Wang, Ruili Li, Yin Wu, Aidong Wen
Pages: 1893-1899
Published online on: 07 February 2017

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Article

TRPM8 downregulation by angiotensin II in vascular smooth muscle cells is involved in hypertension

Fang Huang, Min Ni, Jing‑Ming Zhang, Dong‑Jie Li, Fu‑Ming Shen
Pages: 1900-1908
Published online on: 30 January 2017

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Article

Metformin suppresses the expression of Sonic hedgehog in gastric cancer cells

Zhou Song, Bo Wei, Canrong Lu, Xiaohui Huang, Peiyu Li, Lin Chen
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Identification of miR‑195‑3p as an oncogene in RCC

Lu Jin, Xi Li, Yifan Li, Zeng Zhang, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Min Shi, Zhimao Jiang, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yongqing Lai
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Expression profile of BAFF in peripheral blood from patients of IgA nephropathy: Correlation with clinical features and Streptococcus pyogenes infection

Nuoyan Zheng, Jinjin Fan, Bing Wang, Dongxian Wang, Pinning Feng, Qiongqiong Yang, Xueqing Yu
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Bin Chen, Jia Li, Chongru He, Dahe Li, Wenwen Tong, Yuming Zou, Weidong Xu
Pages: 1943-1951
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Comparison of the early response of human embryonic stem cells and human induced pluripotent stem cells to ionizing radiation

Wiktoria Maria Suchorska, Ewelina Augustyniak, Magdalena Łukjanow
Pages: 1952-1962
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Atorvastatin protects against contrast-induced nephropathy via anti-apoptosis by the upregulation of Hsp27 in vivo and in vitro

Xuyu He, Junqing Yang, Liwen Li, Hong Tan, Ying Wu, Peng Ran, Shuo Sun, Jiyan Chen, Yingling Zhou
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Effects of probiotics on Toll‑like receptor expression in ulcerative colitis rats induced by 2,4,6‑trinitro‑benzene sulfonic acid

Ping Yao, Fang Tan, Hongliang Gao, Lei Wang, Tao Yang, Yongbo Cheng
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Expression profiles and circulation dynamics of rat mesenteric lymph microRNAs

Wakako Sakamoto, Tomohiko Masuno, Hiroyuki Yokota, Toshihiro Takizawa
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Identification of crucial genes associated with rat traumatic spinal cord injury

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Subgingival dysbiosis in smoker and non‑smoker patients with chronic periodontitis

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LMTK3 knockdown retards cell growth and invasion and promotes apoptosis in thyroid cancer

Lu Lu, Xueli Yuan, Qiang Zhang, Hong Zhang, Baozhong Shen
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Pathway‑based detection of idiopathic pulmonary fibrosis at an early stage

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Screening of potential gene markers for predicting carotid atheroma plaque formation using bioinformatics approaches

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Induced pluripotent stem cells from patients with focal cortical dysplasia and refractory epilepsy

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A herbal formula, SYKT, reverses doxorubicin‑induced myelosuppression and cardiotoxicity by inhibiting ROS‑mediated apoptosis

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Lymphatic invasion is a significant indicator of poor patient prognosis in lung squamous cell carcinoma

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IQGAP1‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines Retraction in /10.3892/mmr.2023.13094

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O-GlcNAcylation promotes migration and invasion in human ovarian cancer cells via the RhoA/ROCK/MLC pathway

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Recombinant adeno-associated virus serotype 9 in a mouse model of atherosclerosis: Determination of the optimal expression time in vivo

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Role of hypoxia‑inducible factor‑1α in autophagic cell death in microglial cells induced by hypoxia

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Abnormal differentiation of stem cells into enteroendocrine cells in rats with DSS-induced colitis

Magdy El‑Salhy, Kazuo Umezawa, Jan Gunnar Hatlebakk, Odd Helge Gilja
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Identification of characteristic gene modules of osteosarcoma using bioinformatics analysis indicates the possible molecular pathogenesis

Hongmin Li, Yangke He, Peng Hao, Pan Liu
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Gene expression profiles reveal key pathways and genes associated with neuropathic pain in patients with spinal cord injury

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Dynamics of MMP‑9, MMP‑2 and TIMP‑1 in a rat model of brain injury combined with traumatic heterotopic ossification

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Insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTOR signaling pathway

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Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population

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Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis

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HIF-2α affects proliferation and apoptosis of MG-63 osteosarcoma cells through MAPK signaling

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Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells

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microRNA-125b reverses the multidrug resistance of nasopharyngeal carcinoma cells via targeting of Bcl-2

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Identification of the long non‑coding RNA LET as a novel tumor suppressor in gastric cancer

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Association between injury severity and amyloid β protein levels in serum and cerebrospinal fluid in rats with traumatic spinal cord injury

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Prevalence and spectrum of NKX2.5 mutations in patients with congenital atrial septal defect and atrioventricular block

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Immunosuppressive macrophages induced by IDO1 promote the growth of endometrial stromal cells in endometriosis

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Revealing differential modules in uveal melanoma by analyzing differential networks

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Comprehensive bioinformatics analyses of Crohn's disease

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1,25(OH)2D3/VDR attenuates high glucose‑induced epithelial‑mesenchymal transition in human peritoneal mesothelial cells via the TGFβ/Smad3 pathway

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Cytoprotective effects of myristicin against hypoxia‑induced apoptosis and endoplasmic reticulum stress in rat dorsal root ganglion neurons

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Wogonin protects human retinal pigment epithelium cells from LPS-induced barrier dysfunction and inflammatory responses by regulating the TLR4/NF-κB signaling pathway

Chen Chen, Danni Guo, Guohua Lu
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Genistein decreases A549 cell viability via inhibition of the PI3K/AKT/HIF‑1α/VEGF and NF‑κB/COX‑2 signaling pathways

Juan Zhang, Hongzheng Su, Qingfeng Li, Jing Li, Qianfeng Zhao
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Clinical significance of the phosphorylation of MAPK and protein expression of cyclin D1 in human osteosarcoma tissues

Jian Wu, Lei‑Lei Cui, Jun Yuan, Yuan Wang, Shu Song
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Antiproliferation effect of the uremic toxin para‑cresol on endothelial progenitor cells is related to its antioxidant activity Retraction in /10.3892/mmr.2025.13584

Limin Pan, Xiaoting Ye, Jiguang Ding, Yu Zhou
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Mutational spectrum of CENP-B box and α-satellite DNA on chromosome 21 in Down syndrome children

Qian Chen, Bin Tan, Jun‑Lin He, Xue‑Qing Liu, Xue‑Mei Chen, Ru‑Fei Gao, Jing Zhu, Ying‑Xiong Wang, Hong‑Bo Qi
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Differences in IP‑10, TLR4 and IRF5/3 between SVR and non‑SVR HCV‑1 patients treated with PEG‑IFN and ribavirin

Min Zhang, Yongfang Jiang, Xinqiang Xiao, Milin Peng, Feng Peng, Guozhong Gong
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Fucoidan modulates cytokine production and migration of THP‑1‑derived macrophages via colony‑stimulating factor‑1

Peng Li, Huayang Wang, Qianqian Shao, Beihua Kong, Xun Qu
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Plumbagin prevents osteoarthritis in human chondrocytes through Nrf-2 activation

Yong‑Xian Guo, Liang Liu, Dong‑Zhan Yan, Jian‑Ping Guo
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D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways

Lihua Yu, Jing Yan, Zhiguang Sun
Pages: 2339-2346
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Taraxacum coreanum protects against glutamate-induced neurotoxicity through heme oxygenase-1 expression in mouse hippocampal HT22 cells

Chi-Su Yoon, Wonmin Ko, Dong-Sung Lee, Dong-Cheol Kim, Jongsu Kim, Moonbum Choi, Jin Seon Beom, Ren-Bo An, Hyuncheol Oh, Youn-Chul Kim
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Methotrexate improves perivascular adipose tissue/endothelial dysfunction via activation of AMPK/eNOS pathway

Yanmin Ma, Li Li, Yating Shao, Xiaohong Bai, Tiao Bai, Xinliang Huang
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Downregulation of NPM reverses multidrug resistance in human hepatoma cells via inhibition of P-glycoprotein expression

Fei Luo, Huiyu Li, Jianfang Liang, Hongyan Jia, Xiaoyu Li, Hong Xiao, Xuehua He, Jiefeng He, Yanzhang Tian, Haoliang Zhao
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Protection against Staphylococcus aureus and tetanus infections by a combined vaccine containing SasA and TeNT‑Hc in mice

Yilong Yang, Rui Yu, Xiuxu Yang, Shuling Liu, Ting Fang, Xiaohong Song, Lihua Hou, Changming Yu, Junjie Xu, Ling Fu, Shaoqiong Yi, Wei Chen
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Intraparenchymal treatment with bone marrow mesenchymal stem cell-conditioned medium exerts neuroprotection following intracerebral hemorrhage

Changmeng Cui, Ying Cui, Junling Gao, Ran Li, Xiaohua Jiang, Yanxia Tian, Kaijie Wang, Jianzhong Cui
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Review Open Access

Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Article Open Access

Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Article Open Access

Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Article Open Access

Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Article Open Access

Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Article Open Access

Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Review Open Access

Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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