Extracts from guava fruit protect renal tubular endothelial cells against acetaminophen‑induced cytotoxicity
- Authors:
- Tsai‑Kun Wu
- Hsiao‑Chun Liu
- Shu‑Yu Lin
- Yung‑Luen Yu
- Chyou‑Wei Wei
-
Affiliations: The Ph.D. Program for Cancer Biology and Drug Discovery, China Medical University and Academia Sinica, Taichung 404, Taiwan, R.O.C., Department of Nursing, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan, R.O.C., Department of Nutrition, Master Program of Biomedical Nutrition, Hungkuang University, Taichung 433, Taiwan, R.O.C. - Published online on: January 31, 2018 https://doi.org/10.3892/mmr.2018.8529
- Pages: 5544-5551
This article is mentioned in:
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Bertolini A, Ferrari A, Ottani A, Guerzoni S, Tacchi R and Leone S: Paracetamol: New vistas of an old drug. CNS Drug Rev. 12:250–275. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Klotz U: Paracetamol (acetaminophen) - a popular and widely used nonopioid analgesic. Arzneimittelforschung. 62:355–359. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Yiang GT, Yu YL, Lin KT, Chen JN, Chang WJ and Wei CW: Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cells. Int J Mol Med. 36:485–492. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Bauer M, Babel B, Giesen H and Patzelt D: Fulminant liver failure in a young child following repeated acetaminophen overdosing. J Forensic Sci. 44:1299–1303. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Young RJ: Dextropropoxyphene overdosage. Pharmacological considerations and clinical management. Drugs. 26:70–79. 1983. View Article : Google Scholar : PubMed/NCBI | |
|
Yu YL, Yiang GT, Chou PL, Tseng HH, Wu TK, Hung YT, Lin PS, Lin SY, Liu HC, Chang WJ and Wei CW: Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation. Mol Med Rep. 9:2077–2084. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Hawton K, Bergen H, Simkin S, Arensman E, Corcoran P, Cooper J, Waters K, Gunnell D and Kapur N: Impact of different pack sizes of paracetamol in the United Kingdom and Ireland on intentional overdoses: A comparative study. BMC Public Health. 11:4602011. View Article : Google Scholar : PubMed/NCBI | |
|
Hawton K, Townsend E, Deeks J, Appleby L, Gunnell D, Bennewith O and Cooper J: Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: Before and after study. BMJ. 322:1203–1207. 2001. View Article : Google Scholar : PubMed/NCBI | |
|
Daly FF, Fountain JS, Murray L, Graudins A and Buckley NA; Panel of Australian and New Zealand clinical toxicologists, : Guidelines for the management of paracetamol poisoning in Australia and New Zealand-explanation and elaboration. A consensus statement from clinical toxicologists consulting to the Australasian poisons information centres. Med J Aust. 188:296–301. 2008.PubMed/NCBI | |
|
Guo C, Xie G, Su M, Wu X, Lu X, Wu K and Wei C: Characterization of acetaminophen-induced cytotoxicity in target tissues. Am J Transl Res. 8:4440–4445. 2016.PubMed/NCBI | |
|
Murad HA, Habib H, Kamel Y, Alsayed S, Shakweer M and Elshal M: Thearubigins protect against acetaminophen-induced hepatic and renal injury in mice: Biochemical, histopathological, immunohistochemical, and flow cytometry study. Drug Chem Toxicol. 39:190–198. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Ramachandran A, McGill MR, Xie Y, Ni HM, Ding WX and Jaeschke H: Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice. Hepatology. 58:2099–2108. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Inkielewicz-Stępniak I and Knap N: Effect of exposure to fluoride and acetaminophen on oxidative/nitrosative status of liver and kidney in male and female rats. Pharmacol Rep. 64:902–911. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Slitt AM, Dominick PK, Roberts JC and Cohen SD: Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. Basic Clin Pharmacol Toxicol. 96:487–494. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
McGill MR, Kennon-McGill S, Durham D and Jaeschke H: Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: An in vivo study. Toxicol Mech Methods. 26:104–111. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Galal RM, Zaki HF, Seif El-Nasr MM and Agha AM: Potential protective effect of honey against paracetamol-induced hepatotoxicity. Arch Iran Med. 15:674–680. 2012.PubMed/NCBI | |
|
Wołonciej M, Milewska E and Roszkowska-Jakimiec W: Trace elements as an activator of antioxidant enzymes. Postepy Hig Med Dosw (Online). 70:1483–1498. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Kefer JC, Agarwal A and Sabanegh E: Role of antioxidants in the treatment of male infertility. Int J Urol. 16:449–457. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Lores Arnaiz S, Llesuy S, Cutrín JC and Boveris A: Oxidative stress by acute acetaminophen administration in mouse liver. Free Radic Biol Med. 19:303–310. 1995. View Article : Google Scholar : PubMed/NCBI | |
|
Ji L, Jiang P, Lu B, Sheng Y, Wang X and Wang Z: Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism. J Nutr Biochem. 24:1911–1919. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Wang AY, Lian LH, Jiang YZ, Wu YL and Nan JX: Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway. World J Gastroenterol. 16:384–391. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Ravi K and Divyashree P: Psidium guajava: A review on its potential as an adjunct in treating periodontal disease. Pharmacogn Rev. 8:96–100. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Morais-Braga MFB, Sales DL, Carneiro JNP, Machado AJT, Dos Santos ATL, de Freitas MA, Martins GMAB, Leite NF, de Matos YMLS, Tintino SR, et al: Psidium guajava L. and Psidium brownianum Mart ex DC.: Chemical composition and anti-Candida effect in association with fluconazole. Microb Pathog. 95:200–207. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Shao M, Wang Y, Huang XJ, Fan CL, Zhang QW, Zhang XQ and Ye WC: Four new triterpenoids from the leaves of Psidium guajava. J Asian Nat Prod Res. 14:348–354. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Lin HC and Lin JY: Immune cell-conditioned media suppress prostate cancer PC-3 cell growth correlating with decreased proinflammatory/anti-inflammatory cytokine ratios in the media using 5 selected crude polysaccharides. Integr Cancer Ther. 15:NP13–NP25. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Ashraf A, Sarfraz RA, Rashid MA, Mahmood A, Shahid M and Noor N: Chemical composition, antioxidant, antitumor, anticancer and cytotoxic effects of Psidium guajava leaf extracts. Pharm Biol. 54:1971–1981. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Lin J, Puckree T and Mvelase TP: Anti-diarrhoeal evaluation of some medicinal plants used by Zulu traditional healers. J Ethnopharmacol. 79:53–56. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
Obode O, Okafor O, Erukainure O, Ajayi A, Suberu Y, Ogunji A, Okporua T, Oluwole O, Ozumba A and Elemo G: Protective effect of some selected fruit blends on testicular toxicity in alloxan-induced diabetic rats. J Complement Integr Med. 12:137–142. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Tandon N, Roy M, Roy S and Gupta N: Protective effect of Psidium guajava in arsenic-induced oxidative stress and cytological damage in rats. Toxicol Int. 19:245–249. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Huang CS, Yin MC and Chiu LC: Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats. Food Chem Toxicol. 49:2189–2195. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Soman S, Rauf AA, Indira M and Rajamanickam C: Antioxidant and antiglycative potential of ethyl acetate fraction of Psidium guajava leaf extract in streptozotocin-induced diabetic rats. Plant Foods Hum Nutr. 65:386–391. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Lin CF, Kuo YT, Chen TY and Chien CT: Quercetin-rich guava (Psidium guajava) juice in combination with trehalose reduces autophagy, apoptosis and pyroptosis formation in the kidney and pancreas of type II diabetic rats. Molecules. 21:3342016. View Article : Google Scholar : PubMed/NCBI | |
|
Baek HJ, Lee YM, Kim TH, Kim JY, Park EJ, Iwabuchi K, Mishra L and Kim SS: Caspase-3/7-mediated cleavage of β2-spectrin is required for acetaminophen-induced liver damage. Int J Biol Sci. 12:172–183. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Posadas I, Santos P and Ceña V: Acetaminophen induces human neuroblastoma cell death through NFKB activation. PLoS One. 7:e501602012. View Article : Google Scholar : PubMed/NCBI | |
|
Fu L, Lu W and Zhou X: Phenolic compounds and in vitro antibacterial and antioxidant activities of three tropic fruits: Persimmon, Guava, and Sweetsop. Biomed Res Int. 2016:42874612016. View Article : Google Scholar : PubMed/NCBI | |
|
Cuadrado-Silva CT, Pozo-Bayón MÁ and Osorio C: Targeted metabolomic analysis of polyphenols with antioxidant activity in sour guava (Psidium friedrichsthalianum Nied.) fruit. Molecules. 22:E112016. View Article : Google Scholar : PubMed/NCBI | |
|
Flores G, Wu SB, Negrin A and Kennelly EJ: Chemical composition and antioxidant activity of seven cultivars of guava (Psidium guajava) fruits. Food Chem. 170:327–335. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Araújo HM, Rodrigues FF, Costa WD, Nonato Cde F, Rodrigues FF, Boligon AA, Athayde ML and Costa JG: Chemical profile and antioxidant capacity verification of Psidium guajava (Myrtaceae) fruits at different stages of maturation. EXCLI J. 14:1020–1030. 2015.PubMed/NCBI | |
|
Arrey Tarkang P, Nwachiban Atchan AP, Kuiate JR, Okalebo FA, Guantai AN and Agbor GA: Antioxidant potential of a polyherbal antimalarial as an indicator of its therapeutic value. Adv Pharmacol Sci. 2013:6784582013.PubMed/NCBI | |
|
Lin CY and Yin MC: Renal protective effects of extracts from guava fruit (Psidium guajava L.) in diabetic mice. Plant Foods Hum Nutr. 67:303–308. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Mondal K, Malhotra SP, Jain V and Singh R: Oxidative stress and antioxidant systems in Guava (Psidium guajava L.) fruits during ripening. Physiol Mol Biol Plants. 15:327–334. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Yiang GT, Chen JN, Lin PS, Liu HC, Chen SY and Wei CW: Combined treatment with vitamin E and gefitinib has synergistic effects to inhibit TGF-β1-induced renal fibroblast proliferation. Mol Med Rep. 13:5372–5378. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Kwon YJ, Baek HS, Ye DJ, Shin S, Kim D and Chun YJ: CYP1B1 enhances cell proliferation and metastasis through induction of EMT and activation of Wnt/β-catenin signaling via Sp1 upregulation. PLoS One. 11:e01515982016. View Article : Google Scholar : PubMed/NCBI | |
|
Imig JD and Khan MA: Cytochrome P450 and lipoxygenase metabolites on renal function. Compr Physiol. 6:423–441. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Johnson BP, Walisser JA, Liu Y, Shen AL, McDearmon EL, Moran SM, McIntosh BE, Vollrath AL, Schook AC, Takahashi JS and Bradfield CA: Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proc Natl Acad Sci USA. 111:pp. 18757–18762. 2014; View Article : Google Scholar : PubMed/NCBI | |
|
Yang Y, Wong SE and Lightstone FC: Understanding a substrate's product regioselectivity in a family of enzymes: A case study of acetaminophen binding in cytochrome P450s. PLoS One. 9:e870582014. View Article : Google Scholar : PubMed/NCBI | |
|
Miyakawa K, Albee R, Letzig LG, Lehner AF, Scott MA, Buchweitz JP, James LP, Ganey PE and Roth RA: A cytochrome P450-independent mechanism of acetaminophen-induced injury in cultured mouse hepatocytes. J Pharmacol Exp Ther. 354:230–237. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
McGill MR and Jaeschke H: Metabolism and disposition of acetaminophen: Recent advances in relation to hepatotoxicity and diagnosis. Pharm Res. 30:2174–2187. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Chatuphonprasert W and Jarukamjorn K: Impact of six fruits-banana, guava, mangosteen, pineapple, ripe mango and ripe papaya-on murine hepatic cytochrome P450 activities. J Appl Toxicol. 32:994–1001. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
James LP, Letzig L, Simpson PM, Capparelli E, Roberts DW, Hinson JA, Davern TJ and Lee WM: Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure. Drug Metab Dispos. 37:1779–1784. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Vargha R, Mostafa G, Burda G, Hermon M, Trittenwein G and Gole J: Treatment with N-acetylcystein and total plasma exchange for extracorporeal liver support in children with paracetamol intoxication. Klin Padiatr. 226:84–85. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Prescott LF, Park J, Ballantyne A, Adriaenssens P and Proudfoot AT: Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine. Lancet. 2:432–434. 1977. View Article : Google Scholar : PubMed/NCBI | |
|
Jiang Y, Fan X, Wang Y, Chen P, Zeng H, Tan H, Gonzalez FJ, Huang M and Bi H: Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. Toxicol Sci. 143:107–115. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Yi BR, Kim SU and Choi KC: Synergistic effect of therapeutic stem cells expressing cytosine deaminase and interferon-beta via apoptotic pathway in the metastatic mouse model of breast cancer. Oncotarget. 7:5985–5999. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Tang J, Yan Y, Zhao TC, Gong R, Bayliss G, Yan H and Zhuang S: Class I HDAC activity is required for renal protection and regeneration after acute kidney injury. Am J Physiol Renal Physiol. 307:F303–F316. 2014. View Article : Google Scholar : PubMed/NCBI |
