1
|
Esteller M: Cancer Epigenetics for the
21st Century: What’s Next? Genes Cancer. 2:604–606. 2011.
|
2
|
Daniel FI, Cherubini K, Yurgel LS, de
Figueiredo MA and Salum FG: The role of epigenetic transcription
repression and DNA methyltransferases in cancer. Cancer.
117:677–687. 2011. View Article : Google Scholar : PubMed/NCBI
|
3
|
Bender CM, Pao MM and Jones PA: Inhibition
of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth
of human tumor cell lines. Cancer Res. 58:95–101. 1998.
|
4
|
Fang JY, Cheng ZH, Chen YX, Lu R, Yang L,
Zhu HY and Lu LG: Expression of Dnmt1, demethylase, MeCP2 and
methylation of tumor-related genes in human gastric cancer. World J
Gastroenterol. 10:3394–3398. 2004.PubMed/NCBI
|
5
|
Choi MS, Shim YH, Hwa JY, Lee SK, Ro JY,
Kim JS and Yu E: Expression of DNA methyltransferases in multistep
hepatocarcinogenesis. Hum Pathol. 34:11–17. 2003. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ding WJ, Fang JY, Chen XY and Peng YS: The
expression and clinical significance of DNA methyltransferase
proteins in human gastric cancer. Dig Dis Sci. 53:2083–2089. 2008.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Peng DF, Kanai Y, Sawada M, Ushijima S,
Hiraoka N, Kosuge T and Hirohashi S: Increased DNA
methyltransferase 1 (DNMT1) protein expression in precancerous
conditions and ductal carcinomas of the pancreas. Cancer Sci.
96:403–408. 2005. View Article : Google Scholar : PubMed/NCBI
|
8
|
Arai E, Kanai Y, Ushijima S, Fujimoto H,
Mukai K and Hirohashi S: Regional DNA hypermethylation and DNA
methyltransferase (DNMT) 1 protein overexpression in both renal
tumors and corresponding nontumorous renal tissues. Int J Cancer.
119:288–296. 2006. View Article : Google Scholar : PubMed/NCBI
|
9
|
Vertino PM, Yen RW, Gao J and Baylin SB:
De novo methylation of CpG island sequences in human fibroblasts
overexpressing DNA (cytosine-5-)-methyltransferase. Mol Cell Biol.
16:4555–4565. 1996.PubMed/NCBI
|
10
|
Klotz DM, Nelson SA, Kroboth K, Newton IP,
Radulescu S, Ridgway RA, Sansom OJ, Appleton PL and Näthke IS: The
microtubule poison vinorelbine kills cells independently of mitotic
arrest and targets cells lacking the APC tumour suppressor more
effectively. J Cell Sci. 125:887–895. 2012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Ohta S, Lai EW, Pang AL, Brouwers FM, Chan
WY, Eisenhofer G, de Krijger R, Ksinantova L, Breza J, Blazicek P,
Kvetnansky R, Wesley RA and Pacak K: Downregulation of metastasis
suppressor genes in malignant pheochromocytoma. Int J Cancer.
114:139–143. 2005. View Article : Google Scholar : PubMed/NCBI
|
12
|
Gilham DE, Debets R, Pule M, Hawkins RE
and Abken H: CAR-T cells and solid tumors: tuning T cells to
challenge an inveterate foe. Trends Mol Med. 18:377–384. 2012.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Riccio A and Cubellis MV: Gain of function
in CDKN1C. Nat Genet. 44:737–738. 2012. View Article : Google Scholar : PubMed/NCBI
|
14
|
Harinck F, Kluijt I, van der Stoep N,
Oldenburg RA, Wagner A, Aalfs CM, Sijmons RH, Poley JW, Kuipers EJ,
Fockens P, van Os TA and Bruno MJ: Indication for CDKN2A-mutation
analysis in familial pancreatic cancer families without melanomas.
J Med Genet. 49:362–365. 2012. View Article : Google Scholar : PubMed/NCBI
|
15
|
Guan CN, Zhang PW, Lou HQ, Liao XH and
Chen BY: DLC-1 expression levels in breast cancer assessed by
qRT-PCR are negatively associated with malignancy. Asian Pac J
Cancer Prev. 13:1231–1233. 2012. View Article : Google Scholar : PubMed/NCBI
|
16
|
Liu J, Lin Y, Yang H, Deng Q, Chen G and
He J: The expression of p33(ING1), p53 and autophagy-related gene
Beclin1 in patients with non-small cell lung cancer. Tumour Biol.
32:1113–1121. 2011. View Article : Google Scholar : PubMed/NCBI
|
17
|
Schultz DC, Vanderveer L, Berman DB,
Hamilton TC, Wong AJ and Godwin AK: Identification of two candidate
tumor suppressor genes on chromosome 17p13.3. Cancer Res.
56:1997–2002. 1996.PubMed/NCBI
|
18
|
Vaidyanathan G, Cismowski MJ, Wang G,
Vincent TS, Brown KD and Lanier SM: The Ras-related protein
AGS1/RASD1 suppresses cell growth. Oncogene. 23:5858–5863. 2004.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Berman SD, Calo E, Landman AS, Danielian
PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein
ML, Mukherjee S and Lees JA: Metastatic osteosarcoma induced by
inactivation of Rb and p53 in the osteoblast lineage. Proc Natl
Acad Sci USA. 105:11851–11856. 2008. View Article : Google Scholar : PubMed/NCBI
|
20
|
Kanwal S, Kayani MA and Faryal R:
Identification of novel SNPs in SYK gene of breast cancer patients:
computational analysis of SNPs in the 5′UTR. Mol Biol Rep.
39:8345–8351. 2012.PubMed/NCBI
|
21
|
Behjati R, Kawai K, Inadome Y, Kano J,
Akaza H and Noguchi M: APAF-1 is related to an undifferentiated
state in the testicular germ cell tumor pathway. Cancer Sci.
102:267–274. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Chêne L, Giroud C, Desgrandchamps F,
Boccon-Gibod L, Cussenot O, Berthon P and Latil A: Extensive
analysis of the 7q31 region in human prostate tumors supports TES
as the best candidate tumor suppressor gene. Int J Cancer.
111:798–804. 2004.PubMed/NCBI
|
23
|
da Costa Prando E, Cavalli LR and Rainho
CA: Evidence of epigenetic regulation of the tumor suppressor gene
cluster flanking RASSF1 in breast cancer cell lines. Epigenetics.
6:1413–1424. 2011.PubMed/NCBI
|
24
|
Takahashi M, Fujita M, Furukawa Y,
Hamamoto R, Shimokawa T, Miwa N, Ogawa M and Nakamura Y: Isolation
of a novel human gene, APCDD1, as a direct target of the
beta-Catenin/T-cell factor 4 complex with probable involvement in
colorectal carcinogenesis. Cancer Res. 62:5651–5656.
2002.PubMed/NCBI
|
25
|
Agueli C, Cammarata G, Salemi D, Dagnino
L, Nicoletti R, La Rosa M, Messana F, Marfia A, Bica MG, Coniglio
ML, Pagano M, Fabbiano F and Santoro A: 14q32/miRNA clusters loss
of heterozygosity in acute lymphoblastic leukemia is associated
with up-regulation of BCL11a. Am J Hematol. 85:575–578. 2010.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Zhang X, Liu H, Li B, Huang P, Shao J and
He Z: Tumor suppressor BLU inhibits proliferation of nasopharyngeal
carcinoma cells by regulation of cell cycle, c-Jun N-terminal
kinase and the cyclin D1 promoter. BMC Cancer. 12:2672012.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Wheeler SE, Morariu EM, Bednash JS, Otte
CG, Seethala RR, Chiosea SI and Grandis JR: Lyn kinase mediates
cell motility and tumor growth in EGFRvIII-expressing head and neck
cancer. Clin Cancer Res. 18:2850–2860. 2012. View Article : Google Scholar : PubMed/NCBI
|
28
|
Persson M, andrén Y, Moskaluk CA, Frierson
HF Jr, Cooke SL, Futreal PA, Kling T, Nelander S, Nordkvist A,
Persson F and Stenman G: Clinically significant copy number
alterations and complex rearrangements of MYB and NFIB in head and
neck adenoid cystic carcinoma. Genes Chromosomes Cancer.
51:805–817. 2012. View Article : Google Scholar : PubMed/NCBI
|
29
|
Xiong F, Wu C, Chang J, Yu D, Xu B, Yuan
P, Zhai K, Xu J, Tan W and Lin D: Genetic variation in an
miRNA-1827 binding site in MYCL1 alters susceptibility to
small-cell lung cancer. Cancer Res. 71:5175–5181. 2011. View Article : Google Scholar : PubMed/NCBI
|
30
|
Gilmore TD and Gerondakis S: The c-Rel
transcription factor in development and disease. Genes Cancer.
2:695–711. 2011. View Article : Google Scholar : PubMed/NCBI
|
31
|
Zhang L, Teng Y, Zhang Y, Liu J, Xu L, Qu
J, Hou K, Yang X, Liu Y and Qu X: C-Src-mediated RANKL-induced
breast cancer cell migration by activation of the ERK and Akt
pathway. Oncol Lett. 3:395–400. 2012.PubMed/NCBI
|
32
|
Memarian A, Hojjat-Farsangi M,
Asgarian-Omran H, Younesi V, Jeddi-Tehrani M, Sharifian RA,
Khoshnoodi J, Razavi SM, Rabbani H and Shokri F: Variation in WNT
genes expression in different subtypes of chronic lymphocytic
leukemia. Leuk Lymphoma. 50:2061–2070. 2009. View Article : Google Scholar : PubMed/NCBI
|
33
|
Dwyer MA, Joseph JD, Wade HE, Eaton ML,
Kunder RS, Kazmin D, Chang CY and McDonnell DP: WNT11 expression is
induced by estrogen-related receptor alpha and beta-catenin and
acts in an autocrine manner to increase cancer cell migration.
Cancer Res. 70:9298–9308. 2010. View Article : Google Scholar : PubMed/NCBI
|
34
|
Tanic M, Yanowsky K, Rodriguez-Antona C,
Andrés R, Márquez-Rodas I, Osorio A, Benitez J and Martinez-Delgado
B: Deregulated miRNAs in hereditary breast cancer revealed a role
for miR-30c in regulating KRAS oncogene. PLoS One. 7:e388472012.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Qiu JF, Zhang ZQ, Wang Y and You J:
Lentivirus-mediated RNAi knockdown of VEGFA in RKO colorectal
cancer cells decreases tumor formation and growth in vitro and in
vivo. Int J Clin Exp Pathol. 5:290–298. 2012.PubMed/NCBI
|
36
|
Seyhan AA, Varadarajan U, Choe S, Liu W
and Ryan TE: A genome-wide RNAi screen identifies novel targets of
neratinib resistance leading to identification of potential drug
resistant genetic markers. Mol Biosyst. 8:1553–1570. 2012.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Shen DW and Gottesman MM: RAB8 enhances
TMEM205-mediated cisplatin resistance. Pharm Res. 29:643–650. 2012.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Wang JS, Wang FB, Zhang QG, Shen ZZ and
Shao ZM: Enhanced expression of Rab27A gene by breast cancer cells
promoting invasiveness and the metastasis potential by secretion of
insulin-like growth factor-II. Mol Cancer Res. 6:372–382. 2008.
View Article : Google Scholar : PubMed/NCBI
|
39
|
Shibata D, Mori Y, Cai K, Zhang L, Yin J,
Elahi A, Hamelin R, Wong YF, Lo WK, Chung TK, Sato F, Karpeh MS Jr
and Meltzer SJ: RAB32 hypermethylation and microsatellite
instability in gastric and endometrial adenocarcinomas. Int J
Cancer. 119:801–806. 2006. View Article : Google Scholar : PubMed/NCBI
|
40
|
Cong XL, Li B, Yang RC, Feng SZ, Chen SJ
and Han ZC: Enhanced growth suppression of Philadephia1 leukemia
cells by targeting bcr3/abl2 and VEGF through antisense strategy.
Leukemia. 19:1517–1524. 2005. View Article : Google Scholar : PubMed/NCBI
|
41
|
Sonvilla G, Allerstorfer S, Stättner S,
Karner J, Klimpfinger M, Fischer H, Grasl-Kraupp B, Holzmann K,
Berger W, Wrba F, Marian B and Grusch M: FGF18 in colorectal tumour
cells: autocrine and paracrine effects. Carcinogenesis. 29:15–24.
2008. View Article : Google Scholar : PubMed/NCBI
|
42
|
Delfortrie S, Pinte S, Mattot V, Samson C,
Villain G, Caetano B, Lauridant-Philippin G, Baranzelli MC,
Bonneterre J, Trottein F, Faveeuw C and Soncin F: Egfl7 promotes
tumor escape from immunity by repressing endothelial cell
activation. Cancer Res. 71:7176–7186. 2011. View Article : Google Scholar : PubMed/NCBI
|
43
|
Schenone S, Brullo C, Musumeci F, Biava M,
Falchi F and Botta M: Fyn kinase in brain diseases and cancer: the
search for inhibitors. Curr Med Chem. 18:2921–2942. 2011.
View Article : Google Scholar : PubMed/NCBI
|
44
|
Jacobs JF, van Bokhoven H, van Leeuwen FN,
Hulsbergen-van de Kaa CA, de Vries IJ, Adema GJ, Hoogerbrugge PM
and de Brouwer AP: Regulation of MYCN expression in human
neuroblastoma cells. BMC Cancer. 9:2392009. View Article : Google Scholar : PubMed/NCBI
|
45
|
Lankat-Buttgereit B, Fehmann HC, Hering
BJ, Bretzel RG and Göke B: Expression of the ras-related rab3a gene
in human insulinomas and normal human pancreatic islets. Pancreas.
9:434–438. 1994. View Article : Google Scholar : PubMed/NCBI
|
46
|
Jang KW, Lee KH, Kim SH, Jin T, Choi EY,
Jeon HJ, Kim E, Han YS and Chung JH: Ubiquitin ligase CHIP induces
TRAF2 proteasomal degradation and NF-κB inactivation to regulate
breast cancer cell invasion. J Cell Biochem. 112:3612–3620.
2011.PubMed/NCBI
|
47
|
Kawaguchi-Ihara N, Murohashi I, Nara N and
Tohda S: Promotion of the self-renewal capacity of human acute
leukemia cells by Wnt3A. Anticancer Res. 28:2701–2704.
2008.PubMed/NCBI
|
48
|
Charlton A, Blair V, Shaw D, Parry S,
Guilford P and Martin IG: Hereditary diffuse gastric cancer:
predominance of multiple foci of signet ring cell carcinoma in
distal stomach and transitional zone. Gut. 53:814–820. 2004.
View Article : Google Scholar : PubMed/NCBI
|
49
|
Rountree MR, Bachman KE, Herman JG and
Baylin SB: DNA methylation, chromatin inheritance and cancer.
Oncogene. 20:3156–3165. 2001. View Article : Google Scholar : PubMed/NCBI
|
50
|
Schaefer M, Hagemann S, Hanna K and Lyko
F: Azacytidine inhibits RNA methylation at DNMT2 target sites in
human cancer cell lines. Cancer Res. 69:8127–8132. 2009. View Article : Google Scholar : PubMed/NCBI
|
51
|
Ooi SK, Qiu C, Bernstein E, Li K, Jia D,
Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X
and Bestor TH: DNMT3L connects unmethylated lysine 4 of histone H3
to de novo methylation of DNA. Nature. 448:714–717. 2007.
View Article : Google Scholar : PubMed/NCBI
|
52
|
Bourc’his D, Xu GL, Lin CS, Bollman B and
Bestor TH: Dnmt3L and the establishment of maternal genomic
imprints. Science. 294:2536–2539. 2001.PubMed/NCBI
|
53
|
Jia D, Jurkowska RZ, Zhang X, Jeltsch A
and Cheng X: Structure of Dnmt3a bound to Dnmt3L suggests a model
for de novo DNA methylation. Nature. 449:248–251. 2007. View Article : Google Scholar : PubMed/NCBI
|
54
|
Stefanska B, Huang J, Bhattacharyya B,
Suderman M, Hallett M, Han ZG and Szyf M: Definition of the
landscape of promoter DNA hypomethylation in liver cancer. Cancer
Res. 71:5891–5903. 2011. View Article : Google Scholar : PubMed/NCBI
|
55
|
Tan AC, Jimeno A, Lin SH, Wheelhouse J,
Chan F, Solomon A, Rajeshkumar NV, Rubio-Viqueira B and Hidalgo M:
Characterizing DNA methylation patterns in pancreatic cancer
genome. Mol Oncol. 3:425–438. 2009. View Article : Google Scholar : PubMed/NCBI
|
56
|
Dimberg J, Ström K, Löfgren S, Zar N,
Lindh M and Matussek A: DNA promoter methylation status and protein
expression of interleukin-8 in human colorectal adenocarcinomas.
Int J Colorectal Dis. 27:709–714. 2012. View Article : Google Scholar : PubMed/NCBI
|
57
|
Radhakrishnan VM, Jensen TJ, Cui H,
Futscher BW and Martinez JD: Hypomethylation of the 14-3-3σ
promoter leads to increased expression in non-small cell lung
cancer. Genes Chromosomes Cancer. 50:830–836. 2011.
|