Prostate cancer metastasis to the distal phalanx of the left hallux: The first confirmed case and literature review

Sui,Xinbing; Hu,Yan; Zhang,Cheng; Pan,Hongming; Li,Da

doi:10.3892/ol.2016.4701

Prostate cancer metastasis to the distal phalanx of the left hallux: The first confirmed case and literature review

Authors:
- Xinbing Sui
- Yan Hu
- Cheng Zhang
- Hongming Pan
- Da Li
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Affiliations: Department of Medical Oncology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China, Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China, Department of Medical Oncology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310015, P.R. China
Published online on: June 13, 2016 https://doi.org/10.3892/ol.2016.4701
Pages: 1074-1078

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Abstract

Prostate cancer is one of the most common carcinomas in Asia, as well as all over the world. The vast majority of prostate cancer patients present with bone metastases, which mainly involve the axial bones, with pain as the most common symptom. The present study reports the first case of prostate cancer metastasis to the hallux in a 73-year-old man who presented with pain and a swollen phalanx of the left hallux. This symptom developed gradually over a period of several months and could not be improved with the common treatments. Due to a pathological fracture, amputation of the left phalanx was performed. Notably, the immunohistochemical examinations of the surgical sample demonstrated the presence of a metastatic lesion from prostate cancer. The present study describes an unusual presentation involving phalangeal metastasis in a prostate cancer patient, and a systematic review of reported cases of rare metastatic events in prostate cancer is also discussed.

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