1
|
Tymiak AA, Norman JA, Bolgar M, DiDonato
GC, Lee H, Parker WL, Lo LC, Berova N, Nakanishi K and Haber E:
Physicochemical characterization of a ouabain isomer isolated from
bovine hypothalamus. Proc Natl Acad Sci USA. 90:8189–8193. 1993.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Ludens JH, Clark MA, Robinson FG and
DuCharme DW: Rat adrenal cortex is a source of a circulating
ouabainlike compound. Hypertension. 19:721–724. 1992. View Article : Google Scholar : PubMed/NCBI
|
3
|
Hamlyn JM, Blaustein MP, Bova S, DuCharme
DW, Harris DW, Mandel F, Mathews WR and Ludens JH: Identification
and characterization of a ouabain-like compound from human plasma.
Proc Natl Acad Sci USA. 88:6259–6263. 1991. View Article : Google Scholar : PubMed/NCBI
|
4
|
Manunta P, Stella P, Rivera R, Ciurlino D,
Cusi D, Ferrandi M, Hamlyn JM and Bianchi G: Left ventricular mass,
stroke volume, and ouabain-like factor in essential hypertension.
Hypertension. 34:450–456. 1999. View Article : Google Scholar : PubMed/NCBI
|
5
|
Manunta P, Hamilton BP and Hamlyn JM:
Structure-activity relationships for the hypertensinogenic activity
of ouabain: Role of the sugar and lactone ring. Hypertension.
37:472–477. 2001. View Article : Google Scholar : PubMed/NCBI
|
6
|
Huang BS, Huang X, Harmsen E and Leenen
FH: Chronic central versus peripheral ouabain, blood pressure and
sympathetic activity in rats. Hypertension. 23:1087–1090. 1994.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Winnicka K, Bielawski K, Bielawska A and
Surazyński A: Antiproliferative activity of derivatives of ouabain,
digoxin and proscillaridin A in human MCF-7 and MDA-MB-231 breast
cancer cells. Biol Pharm Bull. 31:1131–1140. 2008. View Article : Google Scholar : PubMed/NCBI
|
8
|
Newman RA, Yang P, Pawlus AD and Block KI:
Cardiac glycosides as novel cancer therapeutic agents. Mol Interv.
8:36–49. 2008. View
Article : Google Scholar : PubMed/NCBI
|
9
|
Tailler M, Senovilla L, Lainey E, Thépot
S, Métivier D, Sébert M, Baud V, Billot K, Fenaux P, Galluzzi L, et
al: Antineoplastic activity of ouabain and pyrithione zinc in acute
myeloid leukemia. Oncogene. 31:3536–3546. 2012. View Article : Google Scholar : PubMed/NCBI
|
10
|
Pezzani R, Rubin B, Redaelli M, Radu C,
Barollo S, Cicala MV, Salvà M, Mian C, Mucignat-Caretta C, Simioni
P, et al: The antiproliferative effects of ouabain and everolimus
on adrenocortical tumor cells. Endocr J. 61:41–53. 2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Brouillard F, Tondelier D, Edelman A and
Baudouin-Legros M: Drug resistance induced by ouabain via the
stimulation of MDR1 gene expression in human carcinomatous
pulmonary cells. Cancer Res. 61:1693–1698. 2001.PubMed/NCBI
|
12
|
Riganti C, Campia I, Polimeni M,
Pescarmona G, Ghigo D and Bosia A: Digoxin and ouabain induce
P-glycoprotein by activating calmodulin kinase II and
hypoxia-inducible factor-1alpha in human colon cancer cells.
Toxicol Appl Pharmacol. 240:385–392. 2009. View Article : Google Scholar : PubMed/NCBI
|
13
|
Cordon-Cardo C, O'Brien JP, Boccia J,
Casals D, Bertino JR and Melamed MR: Expression of the multidrug
resistance gene product (P-glycoprotein) in human normal and tumor
tissues. J Histochem Cytochem. 38:1277–1287. 1990. View Article : Google Scholar : PubMed/NCBI
|
14
|
De Visser KE, Eichten A and Coussens LM:
Paradoxical roles of the immune system during cancer development.
Nat Rev Cancer. 6:24–37. 2006. View
Article : Google Scholar : PubMed/NCBI
|
15
|
Rodrigues-Mascarenhas S, Da Silva de
Oliveira A, Amoedo ND, Affonso-Mitidieri OR, Rumjanek FD and
Rumjanek VM: Modulation of the immune system by ouabain. Ann N Y
Acad Sci. 1153:153–163. 2009. View Article : Google Scholar : PubMed/NCBI
|
16
|
Honig SM, Fu S, Mao X, Yopp A, Gunn MD,
Randolph GJ and Bromberg JS: FTY720 stimulates multidrug
transporter- and cysteinyl leukotriene-dependent T cell chemotaxis
to lymph nodes. J Clin Invest. 111:627–637. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Eisenbraun MD, Mosley RL, Teitelbaum DH
and Miller RA: Altered development of intestinal intraepithelial
lymphocytes in P-glycoprotein-deficient mice. Dev Comp Immunol.
24:783–795. 2000. View Article : Google Scholar : PubMed/NCBI
|
18
|
Gupta S, Kim CH, Tsuruo T and Gollapudi S:
Preferential expression and activity of multidrug resistance gene 1
product (P-glycoprotein), a functionally active efflux pump, in
human CD8+ T cells: A role in cytotoxic effector function. J Clin
Immunol. 12:451–458. 1992. View Article : Google Scholar : PubMed/NCBI
|
19
|
Raghu G, Park SW, Roninson IB and
Mechetner EB: Monoclonal antibodies against P-glycoprotein, an MDR1
gene product, inhibit interleukin-2 release from PHA-activated
lymphocytes. Exp Hematol. 24:1258–1264. 1996.PubMed/NCBI
|
20
|
Valente RC, Capella LS, Nascimento CR,
Braga F, Echevarria-Lima J, Lopes AG and Capella MAM: ABCB1
(P-glycoprotein) but not ABCC1 (MRP1) is downregulated in
peripheral blood mononuclear cells of spontaneously hypertensive
rats. Pflugers Arch. 456:359–368. 2008. View Article : Google Scholar : PubMed/NCBI
|
21
|
Shapiro HM, Schildkraut ER, Curbelo R,
Turner RB, Webb RH, Brown DC and Block MJ: Cytomat-R: A
computer-controlled multiple laser source multiparameter flow
cytophotometer system. J Histochem Cytochem. 25:836–844. 1977.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Hoffman RA, Kung PC, Hansen WP and
Goldstein G: Simple and rapid measurement of human T lymphocytes
and their subclasses in peripheral blood. Proc Natl Acad Sci USA.
77:4914–4917. 1980. View Article : Google Scholar : PubMed/NCBI
|
23
|
Leite DF, Echevarria-Lima J, Salgado LT,
Capella MA, Calixto JB and Rumjanek VM: In vivo and in vitro
modulation of MDR molecules in murine thymocytes. Int
Immunopharmacol. 6:204–215. 2006. View Article : Google Scholar : PubMed/NCBI
|
24
|
Zhang J, Hamlyn JM, Karashima E, Raina H,
Mauban JR, Izuka M, Berra-Romani R, Zulian A, Wier WG and Blaustein
MP: Low-dose ouabain constricts small arteries from
ouabain-hypertensive rats: Implications for sustained elevation of
vascular resistance. Am J Physiol Heart Circ Physiol.
297:H1140–H1150. 2009. View Article : Google Scholar : PubMed/NCBI
|
25
|
Nakanishi K: Basophils as APC in Th2
response in allergic inflammation and parasite infection. Curr Opin
Immunol. 22:814–820. 2010. View Article : Google Scholar : PubMed/NCBI
|
26
|
Cromheecke JL, Nguyen KT and Huston DP:
Emerging role of human basophil biology in health and disease. Curr
Allergy Asthma Rep. 14:4082014. View Article : Google Scholar : PubMed/NCBI
|
27
|
Cole SP: Targeting multidrug resistance
protein 1 (MRP1, ABCC1): Past, present and future. Annu Rev
Pharmacol Toxicol. 54:95–117. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Tacke F, Ginhoux F, Jakubzick C, van
Rooijen N, Merad M and Randolph GJ: Immature monocytes acquire
antigens from other cells in the bone marrow and present them to T
cells after maturing in the periphery. J Exp Med. 203:583–597.
2006. View Article : Google Scholar : PubMed/NCBI
|
29
|
Schiff DE, Kline L, Soldau K, Lee JD,
Pugin J, Tobias PS and Ulevitch RJ: Phagocytosis of gram-negative
bacteria by a unique CD14-dependent mechanism. J Leukoc Biol.
62:786–794. 1997.PubMed/NCBI
|
30
|
Akira S and Hemmi H: Recognition of
pathogen-associated molecular patterns by TLR family. Immunol Lett.
85:85–95. 2003. View Article : Google Scholar : PubMed/NCBI
|
31
|
Ebner S, Hofer S, Nguyen VA, Fürhapter C,
Herold M, Fritsch P, Heufler C and Romani N: A novel role for IL-3:
Human monocytes cultured in the presence of IL-3 and IL-4
differentiate into dendritic cells that produce less IL-12 and
shift Th cell responses toward a Th2 cytokine pattern. J Immunol.
168:6199–6207. 2002. View Article : Google Scholar : PubMed/NCBI
|
32
|
Tian J, Li X, Liang M, Liu L, Xie JX, Ye
Q, Kometiani P, Tillekeratne M, Jin R and Xie Z: Changes in sodium
pump expression dictate the effects of ouabain on cell growth. J
Biol Chem. 284:14921–14929. 2009. View Article : Google Scholar : PubMed/NCBI
|
33
|
Schoner W and Scheiner-Bobis G: Endogenous
and exogenous cardiac glycosides: Their roles in hypertension, salt
metabolism and cell growth. Am J Physiol Cell Physiol.
293:C509–C536. 2007. View Article : Google Scholar : PubMed/NCBI
|
34
|
De Rezende Corrêa G, dos Santos A Araujo,
Fontes C Frederico Leite and de Araujo E Giestal: Ouabain induces
an increase of retinal ganglion cell survival in vitro: The
involvement of protein kinase C. Brain Res. 1049:89–94. 2005.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Valente RC, Nascimento CR, Araujo EG and
Rumjanek VM: Mcd14 expression in human monocytes is downregulated
by ouabain via transactivation of epithelial growth factor receptor
and activation of p38 mitogen-activated protein kinase.
Neuroimmunomodulation. 16:228–236. 2009. View Article : Google Scholar : PubMed/NCBI
|
36
|
Pires V, Harab RC, Olej B and Rumjanek VM:
Ouabain effects on activated lymphocytes: Augmentation of CD25
expression on TPA-stimulated cells and of CD69 on PHA- end
TPA-stimulated cells. Int J Immunopharmacol. 19:143–148. 1997.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Matsumori A, Ono K, Nishio R, Igata H,
Shioi T, Matsui S, Furukawa Y, Iwasaki A, Nose Y and Sasayama S:
Modulation of cytokine production and protection against lethal
endotoxemia by the cardiac glycoside ouabain. Circulation.
96:1501–1506. 1997. View Article : Google Scholar : PubMed/NCBI
|
38
|
Foey AD, Crawford A and Hall ND:
Modulation of cytokine production by human mononuclear cells
following impairment of Na, K-ATPase activity. Biochim Biophys
Acta. 1355:43–49. 1997. View Article : Google Scholar : PubMed/NCBI
|
39
|
de Vasconcelos DI, Leite JA, Carneiro LT,
Piuvezam MR, de Lima MR, de Morais LC, Rumjanek VM and
Rodrigues-Mascarenhas S: Anti-inflammatory and antinociceptive
activity of ouabain in mice. Mediators Inflamm. 2011:9129252011.
View Article : Google Scholar : PubMed/NCBI
|
40
|
De Paiva LS, Costa KM, Canto FB, Cabral
VR, Fucs R, Nobrega A and Rumjanek VM: Modulation of mature B cells
in mice following treatment with ouabain. Immunobiology.
216:1038–1043. 2011. View Article : Google Scholar : PubMed/NCBI
|
41
|
Echevarria-Lima J and Rumjanek VM: Effect
of ouabain on the immune system. Curr Hypertens Rev. 2:83–95. 2006.
View Article : Google Scholar
|
42
|
De Sá Lima L, Kawamoto EM, Munhoz CD,
Kinoshita PF, Orellana AM, Curi R, Rossoni LV, Avellar MC and
Scavone C: Ouabain activates NFκB through an NMDA signaling pathway
in cultured cerebellar cells. Neuropharmacology. 73:327–336. 2013.
View Article : Google Scholar : PubMed/NCBI
|
43
|
Vairo G and Hamilton JA: Activation and
proliferation signals in murine macrophages: Stimulation of Na+,
K+-ATPase activity by hemopoietic growth factors and other agents.
J Cell Physiol. 134:13–24. 1988. View Article : Google Scholar : PubMed/NCBI
|
44
|
Teixeira MP and Rumjanek VM: Ouabain
affects the expression of activation markers, cytokine production
and endocytosis of human monocytes. Mediators Inflamm.
2014:7603682014. View Article : Google Scholar : PubMed/NCBI
|
45
|
Wimazal F, Germing U, Kundi M, Noesslinger
T, Blum S, Geissler P, Baumgartner C, Pfeilstoecker M, Valent P and
Sperr WR: Evaluation of the prognostic significance of eosinophilia
and basophilia in a larger cohort of patients with myelodysplastic
syndromes. Cancer. 116:2372–2381. 2010.PubMed/NCBI
|
46
|
Bishara S, Griffin M, Cargill A, Bali A,
Gore ME, Kaye SB, Shepherd JH and Van Trappen PO: Pre-treatment
white blood cell subtypes as prognostic indicators in ovarian
cancer. Eur J Obstet Gynecol Reprod Biol. 138:71–75. 2008.
View Article : Google Scholar : PubMed/NCBI
|
47
|
Delou JM, Lopes AG and Capella M:
Unveiling the role of multidrug resistance proteins in
hypertension. Hypertension. 54:210–216. 2009. View Article : Google Scholar : PubMed/NCBI
|
48
|
Dostanic I, Paul RJ, Lorenz JN, Theriault
S, Van Huysse JW and Lingrel JB: The alpha2-isoform of Na-K-ATPase
mediates ouabain-induced hypertension in mice and increased
vascular contractility in vitro. Am J Physiol Heart Circ Physiol.
288:H477–H485. 2005. View Article : Google Scholar : PubMed/NCBI
|
49
|
Ueda K, Okamura N, Hirai M, Tanigawara Y,
Saeki T, Kioka N, Komano T and Hori R: Human P-glycoprotein
transports cortisol, aldosterone, and dexamethasone, but not
progesterone. J Biol Chem. 267:24248–24252. 1992.PubMed/NCBI
|
50
|
Van Helvoort A, Smith AJ, Sprong H,
Fritzsche I, Schinkel AH, Borst P and Van Meer G: MDR1
P-glycoprotein is a lipid translocase of broad specificity, while
MDR3 P-glycoprotein specifically translocates phosphatidylcholine.
Cell. 87:507–517. 1996. View Article : Google Scholar : PubMed/NCBI
|