Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review)

  • Authors:
    • Xing Wan
    • Hong Liu
    • Yong Sun
    • Jinlan Zhang
    • Xianbing Chen
    • Ning Chen
  • View Affiliations

  • Published online on: April 10, 2017     https://doi.org/10.3892/ol.2017.6017
  • Pages: 3997-4001
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Strategies for the treatment of cancer remain unsatisfactory due to the poor understanding of the complicated underlying molecular mechanisms of carcinogenesis. A number of types of cancer exhibit a marked association with dietary habits and lifestyles. Therefore, the modulation of dietary habits or lifestyles may be an effective strategy for preventing the formation and progression of cancer. Proteins and polypeptides from soybean have been developed as healthcare products due to their marked activity in inhibiting the progression of cancer at various stages. Lunasin, containing 43 amino acid residues, is one such example of a soybean‑derived polypeptide that has been demonstrated to exhibit marked anti-cancer activity. In the present review, studies of the underlying molecular mechanisms and potential advantages of lunasin in the prevention and treatment of cancer have been examined, to provide a theoretical reference for the development of natural product‑based agents or healthcare products for the prevention and treatment of cancer.
View Figures
View References

Related Articles

Journal Cover

June-2017
Volume 13 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Wan X, Liu H, Sun Y, Zhang J, Chen X and Chen N: Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review). Oncol Lett 13: 3997-4001, 2017
APA
Wan, X., Liu, H., Sun, Y., Zhang, J., Chen, X., & Chen, N. (2017). Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review). Oncology Letters, 13, 3997-4001. https://doi.org/10.3892/ol.2017.6017
MLA
Wan, X., Liu, H., Sun, Y., Zhang, J., Chen, X., Chen, N."Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review)". Oncology Letters 13.6 (2017): 3997-4001.
Chicago
Wan, X., Liu, H., Sun, Y., Zhang, J., Chen, X., Chen, N."Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review)". Oncology Letters 13, no. 6 (2017): 3997-4001. https://doi.org/10.3892/ol.2017.6017