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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2017 Volume 13 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Neoadjuvant chemotherapy for pancreatic cancer: Effects on cancer tissue and novel perspectives (Review)

Hidehiro Tajima, Isamu Makino, Yoshinao Ohbatake, Shinichi Nakanuma, Hironori Hayashi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hiroyuki Takamura, Tetsuo Ohta
Pages: 3975-3981
Published online on: 07 April 2017

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Review Open Access

Strategies for the evaluation of DNA damage and repair mechanisms in cancer (Review)

Gabriela Figueroa‑González, Carlos Pérez‑Plasencia
Pages: 3982-3988
Published online on: 06 April 2017

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Review Open Access

Effect of traditional Chinese medicine components on multidrug resistance in tumors mediated by P-glycoprotein (Review)

Xi Xia, Susan P.C. Cole, Tiange Cai, Yu Cai
Pages: 3989-3996
Published online on: 03 April 2017

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Review

Lunasin: A promising polypeptide for the prevention and treatment of cancer (Review)

Xing Wan, Hong Liu, Yong Sun, Jinlan Zhang, Xianbing Chen, Ning Chen
Pages: 3997-4001
Published online on: 10 April 2017

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Article Open Access

Ocoxin oral solution® as a complement to irinotecan chemotherapy in the metastatic progression of colorectal cancer to the liver

Iera Hernandez‑Unzueta, Aitor Benedicto, Elvira Olaso, Eduardo Sanz, Cristina Viera, Beatriz Arteta, Joana Márquez
Pages: 4002-4012
Published online on: 10 April 2017

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Article Open Access

Application of three-dimensional wire localization and orientation in the resection of non-palpable breast lesions

Dechun Li, Jingjing Xu, Jie Zhang, Dandan Xia, Guoqing Shao
Pages: 4013-4016
Published online on: 10 April 2017

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Article Open Access

High level of calpain1 promotes cancer cell invasion and migration in oral squamous cell carcinoma

Da Ma, Juan Fang, Ying Liu, Jing‑Jing Song, Yan‑Qiong Wang, Juan Xia, Bin Cheng, Zhi Wang
Pages: 4017-4026
Published online on: 03 April 2017

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Article Open Access

Canonical and alternative transcript expression of PAX6 and CXCR4 in pancreatic cancer

Elizabeth C. Little, Jennifer D. Kubic, Ravi Salgia, Paul J. Grippo, Deborah Lang
Pages: 4027-4034
Published online on: 29 March 2017

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Article Open Access

MAPK/P53-mediated FASN expression in bone tumors

Ye Jiang, Xiaofan Yin, Liang Wu, Qiang Qin, Jun Xu
Pages: 4035-4038
Published online on: 10 April 2017

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Article Open Access

MicroRNA-18a inhibits ovarian cancer growth via directly targeting TRIAP1 and IPMK

Ping Liu, Xiaorong Qi, Ce Bian, Fan Yang, Xiaojuan Lin, Shengtao Zhou, Chuan Xie, Xia Zhao, Tao Yi
Pages: 4039-4046
Published online on: 31 March 2017

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Article Open Access

Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer

Felicitas Mungenast, Stefanie Aust, Ignace Vergote, Adriaan Vanderstichele, Jalid Sehouli, Elena Braicu, Sven Mahner, Dan Cacsire Castillo‑Tong, Robert Zeillinger, Theresia Thalhammer
Pages: 4047-4054
Published online on: 03 April 2017

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Article Open Access

Expression of PGC1α in glioblastoma multiforme patients

Sang Yeon Cho, Seon‑Hwan Kim, Min‑Hee Yi, Enji Zhang, Eunjee Kim, Jisoo Park, Eun‑Kyeong Jo, Young Ho Lee, Min Soo Park, Yonghyun Kim, Jongsun Park, Dong Woon Kim
Pages: 4055-4076
Published online on: 03 April 2017

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Article Open Access

Genomic analysis of drug resistant small cell lung cancer cell lines by combining mRNA and miRNA expression profiling

Yitian Chen, Xiang Yang, Yichen Xu, Jiongrui Cao, Longbang Chen
Pages: 4077-4084
Published online on: 31 March 2017

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Article Open Access

Resistance to nanoparticle albumin-bound paclitaxel is mediated by ABCB1 in urothelial cancer cells

Stefan Vallo, Raoul Köpp, Martin Michaelis, Florian Rothweiler, Georg Bartsch, Maximilian P. Brandt, Kilian M. Gust, Felix Wezel, Roman A. Blaheta, Axel Haferkamp, Jindrich Cinatl
Pages: 4085-4092
Published online on: 05 April 2017

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Article Open Access

Efficacy and tolerability of lacosamide for secondary epileptic seizures in patients with brain tumor: A multicenter, observational retrospective study Corrigendum in /10.3892/ol.2017.6689

Juan Manuel Sepúlveda‑Sánchez, Antonio Conde‑Moreno, Manuel Barón, Javier Pardo, Gaspar Reynés, Antonio Belenguer
Pages: 4093-4100
Published online on: 05 April 2017

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Article Open Access

Irradiation of peripheral blood mononuclear cells with 7.5 Gy X‑rays prior to donor lymphocyte infusion inhibits proliferation while preserving cytotoxicity, and improves the effectiveness of HSCT in patients with hematological malignancies

Yong‑Qiu Wei, Xi‑Nan Cen, Hui‑Hui Liu, Yu‑Hua Sun, Yong‑Jin Shi, Wei Liu, Yu‑Jun Dong, Han‑Yun Ren
Pages: 4101-4108
Published online on: 31 March 2017

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Article Open Access

DNA topoisomerase IIα and Ki67 are prognostic factors in patients with hepatocellular carcinoma

Yi Cao, Ruisheng Ke, Shaohu Wang, Xu Zhu, Jianwei Chen, Chao Huang, Yi Jiang, Lizhi Lv
Pages: 4109-4116
Published online on: 06 April 2017

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Article Open Access

Expression of PRR11 protein and its correlation with pancreatic cancer and effect on survival

Song Tan, Zhonghua Jiang, Aihua Hou, Jihua Wang, Jinbo Zhang, Lingling Dai
Pages: 4117-4122
Published online on: 03 April 2017

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Article Open Access

Relationship between DLK1 gene promoter region DNA methylation and non-small cell lung cancer biological behavior Retraction in /10.3892/ol.2020.11577

Zhaokui Zhong, Yongting Ye, Wei Guo, Yi He, Weicai Hu
Pages: 4123-4126
Published online on: 10 April 2017

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Article Open Access

G9A performs important roles in the progression of breast cancer through upregulating its targets

Wenhua Jiang, Pengfei Liu, Xiaodong Li
Pages: 4127-4132
Published online on: 03 April 2017

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Article Open Access

Aberrant expression of AID and AID activators of NF-κB and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers

Takashi Mohri, Keiko Nagata, Satoshi Kuwamoto, Michiko Matsushita, Hirotsugu Sugihara, Masako Kato, Yasushi Horie, Ichiro Murakami, Kazuhiko Hayashi
Pages: 4133-4140
Published online on: 03 April 2017

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Article Open Access

Value of diffusion‑weighted magnetic resonance imaging in predicting World Health Organization grade in G1/G2 pancreatic neuroendocrine tumors

Chuangen Guo, Xiaoling Zhuge, Xiao Chen, Zhongqiu Wang, Wenbo Xiao, Qidong Wang
Pages: 4141-4146
Published online on: 11 April 2017

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Article Open Access

Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma

Zhongwu Su, Guo Li, Chao Liu, Shuling Ren, Tengbo Deng, Shuiting Zhang, Yongquan Tian, Yong Liu, Yuanzheng Qiu
Pages: 4147-4154
Published online on: 31 March 2017

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Article

miR-564 is downregulated in gastric carcinoma and targets E2F3

Yong Guo, Yong Qi, Aitao Guo, Chengxiong Du, Rong Zhang, Xiaoyong Chu
Pages: 4155-4160
Published online on: 31 March 2017

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Article Open Access

Decreased expression of insulin-like growth factor binding protein 6 is associated with gastric adenocarcinoma prognosis

Changqing Zeng, Xingyu Feng, Wei Wang, Lin Lv, Cheng Fang, Liangjie Chi, Liangxiang Huang, Zhiwei Zhou
Pages: 4161-4168
Published online on: 05 April 2017

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Case Report Open Access

Overexpression of the anti-apoptotic protein BAG3 in human choroidal melanoma: A case report

Tatsuya Yunoki, Yoshiaki Tabuchi, Takashi Kondo, Yoko Ishii, Atsushi Hayashi
Pages: 4169-4172
Published online on: 30 March 2017

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Article Open Access

Ell3 stimulates 5-FU resistance in a breast cancer cell line

Isaac Kim, Kwang‑Soo Kim, Ok‑Seon Kwon, Hyuk‑Jin Cha, Kyung‑Soon Park
Pages: 4173-4179
Published online on: 05 April 2017

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Case Report Open Access

Acute promyelocytic leukemia with a cryptic insertion of RARA into PML on chromosome 15 due to uniparental isodisomy: A case report

Anna Venci, Rita Mazza, Orietta Spinelli, Luciana Di Schiena, Daniela Bettio
Pages: 4180-4184
Published online on: 03 April 2017

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Article Open Access

A conditionally replicating adenovirus expressing IL-24 acts synergistically with temozolomide to enhance apoptosis in melanoma cells in vitro

Zhen Liang, Chun‑Sheng Yang, Feng Gu, Lan‑Sheng Zhang
Pages: 4185-4189
Published online on: 07 April 2017

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Article Open Access

Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation

Vaidotas Stankevicius, Karolina Kuodyte, Diana Schveigert, Danute Bulotiene, Tomas Paulauskas, Kristina Daniunaite, Kestutis Suziedelis
Pages: 4190-4200
Published online on: 20 March 2017

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Article Open Access

Age-associated prognostic and predictive biomarkers in patients with breast cancer

Markéta Kolečková, Zdeněk Kolář, Jiří Ehrmann, Gabriela Kořínková, Radek Trojanec
Pages: 4201-4207
Published online on: 06 April 2017

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Article Open Access

A low serum Tat-interacting protein 30 level is a diagnostic and prognostic biomarker for hepatocellular carcinoma

Sha‑Sha Fan, Chu‑Shu Liao, You‑De Cao, Pei‑Ling Xiao, Tan Deng, Rong‑Cheng Luo, Hua‑Xin Duan
Pages: 4208-4214
Published online on: 11 April 2017

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Article Open Access

GALNT14 genotype is associated with perineural invasion, lymph node metastasis and overall survival in resected cholangiocarcinoma

Kung‑Hao Liang, Ta‑Sen Yeh, Ren‑Chin Wu, Chun‑Nan Yeh, Chau‑Ting Yeh
Pages: 4215-4223
Published online on: 05 April 2017

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Article Open Access

Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells

Holger Bronger, Anne Karge, Tobias Dreyer, Daniela Zech, Sara Kraeft, Stefanie Avril, Marion Kiechle, Manfred Schmitt
Pages: 4224-4230
Published online on: 05 April 2017

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Article Open Access

Wnt10B is critical for the progression of gastric cancer

Xiao‑Dan Wu, Qing‑Li Bie, Bin Zhang, Zi‑He Yan, Zhi‑Jun Han
Pages: 4231-4237
Published online on: 05 April 2017

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Article Open Access

IL-17A promotes the proliferation of human nasopharyngeal carcinoma cells through p300-mediated Akt1 acetylation

Kemin Cai, Bing Wang, Hongmei Dou, Ronglan Luan, Xueli Bao, Jiusheng Chu
Pages: 4238-4244
Published online on: 31 March 2017

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Article Open Access

Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Pages: 4245-4251
Published online on: 11 April 2017

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Article Open Access

Dynamic monitoring of circulating microRNAs as a predictive biomarker for the diagnosis and recurrence of papillary thyroid carcinoma

Yanqing Zhang, Desheng Xu, Jiaqi Pan, Zhengkai Yang, Meijun Chen, Jun Han, Sijia Zhang, Lulu Sun, Hong Qiao
Pages: 4252-4266
Published online on: 11 April 2017

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Article Open Access

Identification of potential target genes associated with the effect of propranolol on angiosarcoma via microarray analysis

Shiyong Zhou, Pengfei Liu, Wenhua Jiang, Huilai Zhang
Pages: 4267-4275
Published online on: 31 March 2017

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Article Open Access

Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer

Chul Jang Kim, Yukihiro Tambe, Ken‑Ichi Mukaisho, Hiroyuki Sugihara, Susumu Kageyama, Akihiro Kawauchi, Hirokazu Inoue
Pages: 4276-4284
Published online on: 07 April 2017

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Case Report Open Access

Bosutinib as a fourth-line therapy for a patient with T315I-positive lymphoid blastic phase chronic myeloid leukemia: A case report

Yukiko Komeno, Naoyuki Uchida, Yumiko Satoh, Hideki Uryu, Yuko Iwata, Akiko Masuda, Kuniko Iihara, Yutaka Yatomi, Shuichi Taniguchi, Tomiko Ryu
Pages: 4285-4289
Published online on: 05 April 2017

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Case Report Open Access

Disseminated carcinomatosis of the bone marrow with disseminated intravascular coagulation as the first symptom of recurrent rectal cancer successfully treated with chemotherapy: A case report and review of the literature

Hiroshi Takeyama, Tsutomu Sakiyama, Tomoko Wakasa, Kotaro Kitani, Keisuke Inoue, Hiroaki Kato, Shinya Ueda, Masanori Tsujie, Yoshinori Fujiwara, Masao Yukawa, Yoshio Ohta, Masatoshi Inoue
Pages: 4290-4294
Published online on: 04 April 2017

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Article Open Access

Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma

Liqun Yang, Mengying Huang, Juan Tan, Jianbing Hou, Jiang He, Feng Wang, Hongjuan Cui, Liang Yi
Pages: 4295-4301
Published online on: 12 April 2017

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Article Open Access

The expression of Duffy antigen receptor for chemokines by epithelial ovarian cancer decreases growth potential

Qinyi Zhu, Lu Jiang, Xipeng Wang
Pages: 4302-4306
Published online on: 29 March 2017

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Case Report Open Access

Indolent growth of low-grade myofibroblastic sarcoma of the cheek mimics benign lesions: A case report and literature review

Tessho Maruyama, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Toshihiro Kawano, Kazuhide Nishihara, Akira Arasaki
Pages: 4307-4314
Published online on: 10 April 2017

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Article

Efficacy and tolerability of nanoparticle albumin-bound paclitaxel in combination with carboplatin as a late-phase chemotherapy for recurrent and advanced non-small-cell lung cancer: A multi-center study of the Fukushima lung cancer association group of surgeons

Mitsunori Higuchi, Hironori Takagi, Yuki Owada, Takuya Inoue, Yuzuru Watanabe, Takumi Yamaura, Mitsuro Fukuhara, Satoshi Muto, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Atsushi Yonechi, Jun Osugi, Mika Hoshino, Yutaka Shio, Koichi Fujiu, Ryuzo Kanno, Akio Ohishi, Hiroyuki Suzuki, Mitsukazu Gotoh
Pages: 4315-4321
Published online on: 05 April 2017

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Article

CCAAT/enhancer-binding protein α decreases the viability of gastric cancer cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 4322-4326
Published online on: 05 April 2017

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Article

The role of microvessel density, lymph node metastasis, and tumor size as prognostic factors of distant metastasis in colorectal cancer

Tomonari Cho, Eisuke Shiozawa, Fumihiko Urushibara, Nana Arai, Toshitaka Funaki, Yusuke Takehara, Sakiko Tazawa, Masashi Misawa, Mayumi Homma, Tomoko Norose, Mutsuko Omatsu, Hideyuki Miyachi, Toshiko Yamochi, Toshiaki Kunimura, Genshu Tate, Fumio Ishida, Shin‑Ei Kudo, Masahumi Takimoto
Pages: 4327-4333
Published online on: 31 March 2017

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Article

Expression of regulatory factor X1 can predict the prognosis of breast cancer

Masahiro Shibata, Mitsuro Kanda, Dai Shimizu, Haruyoshi Tanaka, Shinichi Umeda, Masamichi Hayashi, Takahiro Inaishi, Noriyuki Miyajima, Yayoi Adachi, Yuko Takano, Kenichi Nakanishi, Dai Takeuchi, Sumiyo Noda, Yasuhiro Kodera, Toyone Kikumori
Pages: 4334-4340
Published online on: 07 April 2017

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Article

Upregulation of WEE1 is a potential prognostic biomarker for patients with colorectal cancer

Xiao‑Chuan Ge, Fan Wu, Wei‑Tao Li, Xuan‑Jin Zhu, Jian‑Wei Liu, Bai‑Lin Wang
Pages: 4341-4348
Published online on: 04 April 2017

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Article

B-cell specific Moloney leukemia virus insert site 1 and peptidyl arginine deiminase IV positively regulate carcinogenesis and progression of esophageal squamous cell carcinoma

Wei Wang, Huai‑Jun Ji, Ning‑Bo Sun, Xiao‑Tian Chang, Bing Xu, Yao Wang, Ming Cao, Qiang Zhu, Qi Zang, Zhong‑Min Jiang
Pages: 4349-4356
Published online on: 06 April 2017

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Article

Growth inhibition of human breast carcinoma cells by overexpression of regulator of G-protein signaling 4

Hyun‑Jung Park, Seung‑Hyun Kim, Dong‑Oh Moon
Pages: 4357-4363
Published online on: 07 April 2017

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Article

Androgen deprivation therapy has no effect on Pim-1 expression in a mouse model of prostate cancer

Jiang Wang, Gang Li, Bo Li, Hualin Song, Zhiqun Shang, Ning Jiang, Yuanjie Niu
Pages: 4364-4370
Published online on: 07 April 2017

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Article

Anti‑proliferative and anti‑metastasis effects of ten oligostilbenes from the seeds of Paeonia suffruticosa on human cancer cells

Ying Gao, Chunnian He
Pages: 4371-4377
Published online on: 04 April 2017

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Article

Identification of candidate drugs for the treatment of metastatic osteosarcoma through a subpathway analysis method

Xin Li, Ming‑Lan Yan, Qian Yu
Pages: 4378-4384
Published online on: 29 March 2017

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Article Open Access

The clinical analysis of small supernumerary marker chromosomes in 17 children with mos 45,X/46,X,+mar karyotype

Hongying Wang, Ting Wang, Naichao Yang, Yaxiang He, Linqi Chen, Liyi Hong, Xuejun Shao, Hong Li, Hong Zhu, Haibo Li
Pages: 4385-4389
Published online on: 31 March 2017

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Article

Effects of silencing endothelin‑1 on invasion and vascular formation in lung cancer

Zhen‑Yu Zhang, Li‑Li Chen, Wei Xu, Keshavraj Sigdel, Xing‑Tang Jiang
Pages: 4390-4396
Published online on: 11 April 2017

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Article

Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia

Ruei‑Nian Li, Chien‑Yu Li, Chien‑Hung Lee, Chiung‑Yu Peng, Ming‑Tsang Wu
Pages: 4397-4401
Published online on: 03 April 2017

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Article

Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Yawei Shi, Yang Zhao, Nan Shao, Runyi Ye, Yin Lin, Ning Zhang, Wen Li, Yunjian Zhang, Shenming Wang
Pages: 4402-4412
Published online on: 11 April 2017

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Article

Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazone

Jing Xie, Shanshan Shen, Ruhua Chen, Jun Xu, Kun Dong, Jiancui Huang, Qin Lu, Wenjiao Zhu, Tieliang Ma, Lei Jia, Hongxin Cai, Taofeng Zhu
Pages: 4413-4419
Published online on: 10 April 2017

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Article

Maximum standardized uptake value on FDG‑PET predicts survival in stage I non‑small cell lung cancer following carbon ion radiotherapy

Katsuyuki Shirai, Takanori Abe, Jun‑Ichi Saitoh, Tatsuji Mizukami, Daisuke Irie, Yosuke Takakusagi, Shintaro Shiba, Naoko Okano, Takeshi Ebara, Tatsuya Ohno, Takashi Nakano
Pages: 4420-4426
Published online on: 29 March 2017

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Article

Sulforaphane sensitizes human breast cancer cells to paclitaxel‑induced apoptosis by downregulating the NF‑κB signaling pathway

Seung‑Hyun Kim, Hyun‑Jung Park, Dong‑Oh Moon
Pages: 4427-4432
Published online on: 29 March 2017

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Article

Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene mutations

Pawel Krawczyk, Dariusz M. Kowalski, Rodryg Ramlau, Ewa Kalinka‑Warzocha, Kinga Winiarczyk, Katarzyna Stencel, Tomasz Powrózek, Katarzyna Reszka, Kamila Wojas‑Krawczyk, Maciej Bryl, Magdalena Wójcik‑Superczyńska, Maciej Głogowski, Aleksander Barinow‑Wojewódzki, Janusz Milanowski, Maciej Krzakowski
Pages: 4433-4444
Published online on: 03 April 2017

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Case Report

Neoadjuvant chemotherapy in borderline resectable pancreatic cancer: A case report

Maria Celeste Palmarocchi, Ruben Carlo Balzarotti Canger, Piercarlo Saletti
Pages: 4445-4452
Published online on: 11 April 2017

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Article

Oxymatrine inhibits proliferation of human bladder cancer T24 cells by inducing apoptosis and cell cycle arrest

Shun Li, Yi Zhang, Qingyong Liu, Qingli Zhao, Liuyu Xu, Shengliang Huang, Shiming Huang, Xuebin Wei
Pages: 4453-4458
Published online on: 07 April 2017

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Article

Giant cell tumor of the tendon sheath: Magnetic resonance imaging findings in 38 patients

Chao Wang, Rui‑Rui Song, Ping‑Ding Kuang, Liu‑Hong Wang, Min‑Ming Zhang
Pages: 4459-4462
Published online on: 07 April 2017

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Article

AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer

Ahmed S.K. Al‑Khafaji, Michael W. Marcus, Michael P.A. Davies, Janet M. Risk, Richard J. Shaw, John K. Field, Triantafillos Liloglou
Pages: 4463-4468
Published online on: 07 April 2017

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Article

Low expression of miR-1469 predicts disease progression and unfavorable post‑surgical clinical outcomes in patients with esophageal squamous cell cancer

Jin Liu, Chuifang Wang, Xiangyan Liu, Yu Wang, Haibo Liu, Guohua Ren, Liangming Zhu, Zhigang Sun, Zhitao Chen
Pages: 4469-4474
Published online on: 30 March 2017

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Article

Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line

Ladan Dawoody Nejad, Alireza Biglari, Tiziana Annese, Domenico Ribatti
Pages: 4475-4480
Published online on: 31 March 2017

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Article

Overexpression of the androgen receptor in human hepatoma cells and its effect on fatty acid metabolism

Tatsuo Kanda, Xia Jiang, Masato Nakamura, Yuki Haga, Reina Sasaki, Shuang Wu, Shingo Nakamoto, Fumio Imazeki, Osamu Yokosuka
Pages: 4481-4486
Published online on: 03 April 2017

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Article

lncRNA C22orf32-1 contributes to the tumorigenesis of nasopharyngeal carcinoma

Guo‑Hui Nie, Zhao Li, Hong‑Fang Duan, Liang Luo, Hong‑Yi Hu, Wei‑Qiang Yang, Li‑Ping Nie, Ru‑Fei Zhu, Xiao‑Fan Chen, Wei Zhang
Pages: 4487-4492
Published online on: 11 April 2017

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Article

Design and synthesis of novel N(4)-substituted thiosemicarbazones bearing a pyrrole unit as potential anticancer agents

Taofeng Zhu, Shanshan Shen, Qin Lu, Xingpei Ye, Weiliang Ding, Ruhua Chen, Jing Xie, Wenjiao Zhu, Jun Xu, Lei Jia, Weina Wu, Tieliang Ma
Pages: 4493-4500
Published online on: 05 April 2017

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Article

The distribution of human rectal aberrant crypt foci and criteria for defining the counting area

Tetsuro Fujii, Eiji Sakai, Hirokazu Takahashi, Eiji Yamada, Hidenori Ohkubo, Takuma Higurashi, Atsushi Nakajima
Pages: 4501-4504
Published online on: 07 April 2017

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Article

Interleukin-24 inhibits osteosarcoma cell migration and invasion via the JNK/c-Jun signaling pathways

Baobiao Zhuo, Yingchun Shi, Haihui Qin, Qingzeng Sun, Zhengwei Li, Fengfei Zhang, Rong Wang, Xiaodong Wang
Pages: 4505-4511
Published online on: 05 April 2017

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Article

miR-125b is associated with renal cell carcinoma cell migration, invasion and apoptosis

Lu Jin, Zeng Zhang, Yifan Li, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Yaoting Gui, Yun Chen, Yongqing Lai
Pages: 4512-4520
Published online on: 04 April 2017

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Article

Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis

Qun Lu, Junlong Zhuang, Hongqian Guo
Pages: 4521-4525
Published online on: 04 April 2017

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Article

TUC338 promotes cell migration and invasion by targeting TIMP1 in cervical cancer

Qin Li, Feiyang Shen, Chenghai Wang
Pages: 4526-4532
Published online on: 03 April 2017

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Article

Differential expression of the Notch1 receptor, and its ligands Dll1, Dll3 and Dll4 in distinct human pituitary adenoma subtypes

Jianfu Zhang, Hua Gao, Yazhuo Zhang
Pages: 4533-4539
Published online on: 05 April 2017

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Article

Downregulation of NAD(P)H:quinone oxidoreductase 1 inhibits proliferation, cell cycle and migration of cholangiocarcinoma cells

Siriwoot Butsri, Veerapol Kukongviriyapan, Laddawan Senggunprai, Sarinya Kongpetch, Ponsilp Zeekpudsa, Auemduan Prawan
Pages: 4540-4548
Published online on: 29 March 2017

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Article

Dynamic monitoring of EGFR mutations in circulating cell-free DNA for EGFR-mutant metastatic patients with lung cancer: Early detection of drug resistance and prognostic significance

Jianjiao Ni, Linqian Weng, Yi Liu, Zhao Sun, Chunmei Bai, Yingyi Wang
Pages: 4549-4557
Published online on: 11 April 2017

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Article

Morusin induces apoptosis by regulating expression of Bax and Survivin in human breast cancer cells

Sukmin Kang, Eun‑Ok Kim, Sung‑Hoon Kim, Jun‑Hee Lee, Kwang Seok Ahn, Miyong Yun, Seok‑Geun Lee
Pages: 4558-4562
Published online on: 07 April 2017

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Review Open Access

E‑cadherin: A potential biomarker of colorectal cancer prognosis (Review)

Niki Christou, Aurélie Perraud, Sabrina Blondy, Marie‑Odile Jauberteau, Serge Battu, Muriel Mathonnet
Pages: 4571-4576
Published online on: 20 April 2017

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Review

Epithelial-mesenchymal transition in cancer: Role of the IL-8/IL-8R axis (Review)

Zhiwei Zhao, Shichao Wang, Yingbo Lin, Yali Miao, Ye Zeng, Yongmei Nie, Peng Guo, Guangyao Jiang, Jiang Wu
Pages: 4577-4584
Published online on: 13 April 2017

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Review

Advances in recurrence and malignant transformation of sinonasal inverted papillomas (Review)

Qingjia Sun, Lifeng An, Jun Zheng, Dongdong Zhu
Pages: 4585-4592
Published online on: 24 April 2017

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Review

Effects of traditional oriental medicines as anti-cytotoxic agents in radiotherapy (Review)

Wanyeon Kim, Jihoon Kang, Sungmin Lee, Buhyun Youn
Pages: 4593-4601
Published online on: 18 April 2017

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Article Open Access

SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial Δψ in neuroblastoma cells

Smita Tanpure, Jerusha Boyineini, Manu Gnanamony, Reuben Antony, Karen S. Fernández, Jaime Libes, Julian Lin, David Pinson, Pushpa A. Joseph, Christopher S. Gondi
Pages: 4602-4610
Published online on: 24 April 2017

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Article Open Access

Detection of Tax-specific CTLs in lymph nodes of adult T-cell leukemia/lymphoma patients and its association with Foxp3 positivity of regulatory T-cell function

Ayako Ichikawa, Hiroaki Miyoshi, Fumiko Arakawa, Junichi Kiyasu, Kensaku Sato, Daisuke Niino, Yoshizo Kimura, Maki Yoshida, Riko Kawano, Hiroko Muta, Yasuo Sugita, Koichi Ohshima
Pages: 4611-4618
Published online on: 21 April 2017

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Article Open Access

Synergistic activity of the histone deacetylase inhibitor trichostatin A and the proteasome inhibitor PS-341 against taxane-resistant ovarian cancer cell lines

Xin Jin, Yong Fang, Yi Hu, Jing Chen, Wei Liu, Gang Chen, Mei Gong, Peng Wu, Tao Zhu, Shixuan Wang, Jianfeng Zhou, Hui Wang, Ding Ma, Kezhen Li
Pages: 4619-4626
Published online on: 13 April 2017

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Article Open Access

Cancer gene panel analysis of cultured circulating tumor cells and primary tumor tissue from patients with breast cancer

Eunjoo Hwang, Ji‑Hyun Uh, Hye Seon Lee, Cham Han Lee, Soo Jeong Lee, Sei Hyun Ahn, Byung Ho Son, Jong Won Lee, Jong Han Yu, Nak‑Jung Kwon, Woo Chung Lee, Kap‑Seok Yang, Sung Ho Choi, Myoung Shin Kim, Jinseon Lee, Byung Hee Jeon
Pages: 4627-4632
Published online on: 24 April 2017

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Article Open Access

Palliative treatment of patients with inoperable locally advanced, recurrent or metastatic head and neck squamous cell cancer, using a low-dose and personalized chemotherapeutic regimen

Rohit Bishnoi, Jeffery Bennett, David N. Reisman
Pages: 4633-4640
Published online on: 21 April 2017

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Article Open Access

DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms

Ana P. Azevedo, Susana N. Silva, João P. de Lima, Alice Reichert, Fernando Lima, Esmeraldina Júnior, José Rueff
Pages: 4641-4650
Published online on: 21 April 2017

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Case Report

Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report

Wen‑Wen Sun, Zhi‑Hong Xu, Chao-Fu Wang, Fang Wu, Jiu‑Mei Cao, Pei‑Jing Cui, Wei Huang, Xiao‑Long Jin, Biao Li, Ke‑Min Chen, Bei‑Li Gao, Jia‑An Hu
Pages: 4651-4656
Published online on: 20 April 2017

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Article Open Access

IL-6 and TNF-α promote metastasis of lung cancer by inducing epithelial-mesenchymal transition

Guan-Sheng Shang, Lunxu Liu, Yi-Wei Qin
Pages: 4657-4660
Published online on: 19 April 2017

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Article Open Access

Association between CXCL16/CXCR6 expression and the clinicopathological features of patients with non-small cell lung cancer

Chuangwu Ke, Yanchen Ren, Lu Lv, Weidong Hu, Wenhui Zhou
Pages: 4661-4668
Published online on: 24 April 2017

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Article Open Access

Clinical significance of coagulation factors in operable colorectal cancer

Suee Lee, Seok Jae Huh, Sung Yong Oh, Myeong Seok Koh, Sung‑Hyun Kim, Ji Hyun Lee, Jin Young Han, Hong Jo Choi, Su Jin Kim, Hyo‑Jin Kim
Pages: 4669-4674
Published online on: 20 April 2017

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Article Open Access

Clinical analysis of bevacizumab targeting therapy in treating early colorectal carcinoma after operation

Tie-Ling Li, Zhi-Guo Sun, Xiaoming Jiang, Hai-Feng Guo
Pages: 4675-4678
Published online on: 24 April 2017

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Article Open Access

MED23 in endocrinotherapy for breast cancer

Benrui Lin, Lan Zhang, Dinuo Li, Hongzhi Sun
Pages: 4679-4684
Published online on: 13 April 2017

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Article Open Access

The lipid metabolism gene FTO influences breast cancer cell energy metabolism via the PI3K/Akt signaling pathway

Yazhuo Liu, Ruoyu Wang, Lichuan Zhang, Jianhua Li, Keli Lou, Bingyin Shi
Pages: 4685-4690
Published online on: 13 April 2017

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Article Open Access

Analysis of the correlation between the expression of miR-655 and esophageal cancer prognosis

Peng Chang, Xiangjun Wang, Ya Zhou, Yulong Hou
Pages: 4691-4694
Published online on: 19 April 2017

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Article Open Access

Upregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1

Jing‑Hao Wang, Xiu‑Wen Wang, Di Qu, Ji‑Wen Sun, Fei‑Xiao Guo, Dan Lu
Pages: 4695-4700
Published online on: 24 April 2017

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Article Open Access

miR‑200b inhibits CD133+ glioma cells by targeting the AKT pathway

Aiqun Liu, Qingyun Yu, Zhongxing Peng, Yeqing Huang, Shengpeng Diao, Jing Cheng, Wentao Wang, Mingfan Hong
Pages: 4701-4707
Published online on: 20 April 2017

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Article Open Access

Molecular characterization of breast cancer cell lines by clinical immunohistochemical markers

André de Lima Mota, Adriane Feijo Evangelista, Taciane Macedo, Renato Oliveira, Cristovam Scapulatempo‑Neto, René Aloisio da Costa Vieira, Marcia Maria Chiquitelli Marques
Pages: 4708-4712
Published online on: 25 April 2017

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Article Open Access

Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer

Kentaro Nakayama, Munmun Rahman, Mohammed Tanjimur Rahman, Kohei Nakamura, Emi Sato, Hiroshi Katagiri, Tomoka Ishibashi, Masako Ishikawa, Kouji Iida, Sultana Razia, Noriyuki Ishikawa, Satoru Kyo
Pages: 4713-4719
Published online on: 26 April 2017

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Article Open Access

Colorectal cancer in cases of multiple primary cancers: Clinical features of 59 cases and point mutation analyses

Anshan Wu, Siqi He, Jingjing Li, Ling Liu, Chunlan Liu, Qi Wang, Xiaowei Peng, Jianda Zhou, Pei‑Guo Cao, Ke Cao
Pages: 4720-4726
Published online on: 26 April 2017

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Article Open Access

Reduction of miR-21 induces SK-N-SH cell apoptosis and inhibits proliferation via PTEN/PDCD4

Zuopeng Wang, Wei Yao, Kai Li, Na Zheng, Chao Zheng, Xiaolong Zhao, Shan Zheng
Pages: 4727-4733
Published online on: 20 April 2017

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Article Open Access

Pathogenic mechanism of miR-21 in autoimmune lymphoid hyperplasia syndrome

Yonglong Yan, Xinna Deng, Xiaoran Ning, Fang Li, Jingjing Cao
Pages: 4734-4740
Published online on: 13 April 2017

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Article Open Access

Therapeutic results of a novel enzyme‑targeting radiosensitization treatment, Kochi oxydol-radiation therapy for unresectable carcinomas II, in patients with stage I primary breast cancer

Nobutaka Aoyama, Yasuhiro Ogawa, Miki Yasuoka, Kenta Ohgi, Hitomi Iwasa, Kana Miyatake, Rika Yoshimatsu, Tomoaki Yamanishi, Norihiko Hamada, Taiji Tamura, Kana Kobayashi, Yoriko Murata, Mitsuhiko Miyamura, Takuji Yamagami
Pages: 4741-4747
Published online on: 21 April 2017

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Article Open Access

Synergistic cytotoxic effects of a combined treatment of a Pinellia pedatisecta lipid-soluble extract and cisplatin on human cervical carcinoma in vivo

Mingxing Zhang, Yi Yu, Hongwei Zhang, Haixia Huang, Qingqing Cai, Yu Kang, Guiling Li, Congjian Xu
Pages: 4748-4754
Published online on: 25 April 2017

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Article Open Access

Identification of gene markers associated with metastasis in clear cell renal cell carcinoma

Hailing Yang, Pengfei Huo, Guozhang Hu, Bo Wei, Dalian Kong, Hongjun Li
Pages: 4755-4761
Published online on: 24 April 2017

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Article Open Access

Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cells in vitro and in vivo

Ying Wang, Shoujun Yuan, Linna Li, Dexuan Yang, Chengwang Xu, Shanshan Wang, Danshen Zhang
Pages: 4762-4768
Published online on: 19 April 2017

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Article Open Access

MicroRNA-375 suppresses esophageal cancer cell growth and invasion by repressing metadherin expression

Changmei Hu, Liang Lv, Jie Peng, Deliang Liu, Xuehong Wang, Yuqian Zhou, Jirong Huo
Pages: 4769-4775
Published online on: 26 April 2017

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Article Open Access

Dynamin 3 suppresses growth and induces apoptosis of hepatocellular carcinoma cells by activating inducible nitric oxide synthase production

Chao Gu, Junliang Yao, Peilong Sun
Pages: 4776-4784
Published online on: 20 April 2017

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Article Open Access

Downregulation of eIF4G by microRNA-503 enhances drug sensitivity of MCF-7/ADR cells through suppressing the expression of ABC transport proteins

Xia Pan, Xiaoyan Yang, Jinglei Zang, Si Zhang, Nan Huang, Xinxin Guan, Jianhua Zhang, Zhihui Wang, Xi Li, Xiaoyong Lei
Pages: 4785-4793
Published online on: 19 April 2017

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Article Open Access

Maternal embryonic leucine zipper kinase inhibits epithelial-mesenchymal transition by regulating transforming growth factor-β signaling

Jianjian Cheng, Binyu Qin, Bao Liu, Taibo Huang, Yuguang Li, Lijun Ma
Pages: 4794-4798
Published online on: 24 April 2017

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Article Open Access

Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma

Zensho Ito, Kazuki Takakura, Machi Suka, Tomoya Kanai, Ryota Saito, Shuichi Fujioka, Mikio Kajihara, Hiroyuki Yanagisawa, Takeyuki Misawa, Tadashi Akiba, Shigeo Koido, Toshifumi Ohkusa
Pages: 4799-4805
Published online on: 21 April 2017

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Article Open Access

Grifolin induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways

Hong Yan, Xiaoxia Che, Qingtao Lv, Lili Zhang, Samina Dongol, Yilin Wang, Hengzi Sun, Jie Jiang
Pages: 4806-4812
Published online on: 25 April 2017

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Case Report Open Access

An unusual case of pseudomyxoma peritonei associated with synchronous primary mucinous tumors of the ovary and appendix: A case report

Dong Soo Suh, Yong Jung Song, Byung Su Kwon, Sul Lee, Nam Kyung Lee, Kyung Un Choi, Ki Hyung Kim
Pages: 4813-4817
Published online on: 24 April 2017

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Article Open Access

Effects of programmed death-ligand 1 expression on OK-432 immunotherapy following transurethral resection in non-muscle invasive bladder cancer

Zhi‑Hua Liu, Fu‑Fu Zheng, Yu‑Ling Mao, Lie‑Fu Ye, Jun Bian, De‑Hui Lai, Yun‑Lin Ye, Yu‑Ping Dai
Pages: 4818-4824
Published online on: 24 April 2017

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Article Open Access

Anticancer effect of curcumin inhibits cell growth through miR-21/PTEN/Akt pathway in breast cancer cell

Xinzheng Wang, Yakai Hang, Jinbiao Liu, Yongqiang Hou, Ning Wang, Mingjun Wang
Pages: 4825-4831
Published online on: 20 April 2017

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Article

Conversion to monotherapy with luteinizing‑hormone releasing hormone agonist or orchiectomy after reaching PSA nadir following maximal androgen blockade is able to prolong progression‑free survival in patients with metastatic prostate cancer: A propensity score matching analysis

Gyeong Eun Min, Hanjong Ahn
Pages: 4832-4836
Published online on: 20 April 2017

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Article

miRNA-34a enhances the sensitivity of gastric cancer cells to treatment with paclitaxel by targeting E2F5

Lina Li, Cuiling Wu, Yue Zhao
Pages: 4837-4842
Published online on: 18 April 2017

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Article

Knockout of krüppel-like factor 10 suppresses hepatic cell proliferation in a partially hepatectomized mouse model

Seung‑Ho Heo, Eui‑Suk Jeong, Kyoung‑Sun Lee, Jin‑Hee Seo, Woon‑Kyu Lee, Yang‑Kyu Choi
Pages: 4843-4848
Published online on: 19 April 2017

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Article Open Access

Anti-rheumatic drug iguratimod protects against cancer-induced bone pain and bone destruction in a rat model

Yue Sun, Ying‑Xing Wu, Peng Zhang, Guang Peng, Shi‑Ying Yu
Pages: 4849-4856
Published online on: 19 April 2017

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Article

Calreticulin is a novel independent prognostic factor for oral squamous cell carcinoma

Koji Harada, Takanori Takenawa, Tarannum Ferdous, Yasuhiro Kuramitsu, Yoshiya Ueyama
Pages: 4857-4862
Published online on: 20 April 2017

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Article

TRUS-guided transperineal prostate 12+X core biopsy with template for the diagnosis of prostate cancer

Gang Guo, Yong Xu, Xu Zhang
Pages: 4863-4867
Published online on: 20 April 2017

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Article

Histone deacetylase inhibitor trichostatin A enhances the antitumor effect of the oncolytic adenovirus H101 on esophageal squamous cell carcinoma in vitro and in vivo

Junfen Ma, Nan Li, Jimin Zhao, Jing Lu, Yanqiu Ma, Qinghua Zhu, Ziming Dong, Kangdong Liu, Liang Ming
Pages: 4868-4874
Published online on: 21 April 2017

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Article

Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway

Deyou Wang, Sifeng Tang, Qiwen Zhang
Pages: 4875-4881
Published online on: 21 April 2017

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Article

Circulating tumor cell detection: A direct comparison between negative and unbiased enrichment in lung cancer

Yan Xu, Biao Liu, Fengan Ding, Xiaodie Zhou, Pin Tu, Bo Yu, Yan He, Peilin Huang
Pages: 4882-4886
Published online on: 19 April 2017

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Case Report

Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report

Run‑Song Jiang, Zheng‑Yan Zhao
Pages: 4887-4891
Published online on: 20 April 2017

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Article

Histological evaluations of primary lesions are independently associated with prognosis in patients with gastric cancer who receive neoadjuvant chemotherapy

Tomomitsu Tahara, Tomoyuki Shibata, Masaaki Okubo, Dai Yoshida, Tomohiko Kawamura, Noriyuki Horiguchi, Takamitsu Ishizuka, Mitsuo Nagasaka, Yoshihito Nakagawa, Naoki Ohmiya
Pages: 4892-4896
Published online on: 18 April 2017

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Article

Blueberries inhibit cyclooxygenase-1 and cyclooxygenase-2 activity in human epithelial ovarian cancer

Wumei Lin, Zhigang Li
Pages: 4897-4904
Published online on: 25 April 2017

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Article

Cucurbitacin E induces apoptosis of human prostate cancer cells via cofilin-1 and mTORC1

Xiaolong He, Qi Gao, Yayong Qiang, Wei Guo, Yadong Ma
Pages: 4905-4910
Published online on: 24 April 2017

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Article

Investigation of the relative biological effectiveness and uniform isobiological killing effects of irradiation with a clinical carbon SOBP beam on DNA repair deficient CHO cells

Shigeaki Sunada, Ian M. Cartwright, Hirokazu Hirakawa, Akira Fujimori, Mitsuru Uesaka, Takamitsu A. Kato
Pages: 4911-4916
Published online on: 21 April 2017

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Article

Use of gemcitabine as a second‑line treatment following chemotherapy with folfirinox for metastatic pancreatic adenocarcinoma

Matthieu Sarabi, Laetitia Mais, Nadia Oussaid, Françoise Desseigne, Pierre Guibert, Christelle De La Fouchardiere
Pages: 4917-4924
Published online on: 20 April 2017

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Article

Monoclonal antibodies against autocrine motility factor suppress gastric cancer

Hahn‑Sun Jung, Su In Lee, Seung‑Hoon Kang, Jin Sang Wang, Eun Hee Yang, Byungwook Jeon, Jayhyuk Myung, Ji Young Baek, Song‑Kyu Park
Pages: 4925-4932
Published online on: 13 April 2017

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Article

Differences in the sensitivity of ovarian cancer to photodynamic therapy and the mechanisms for those differences

Yoshihito Yokoyama, Tatsuhiko Shigeto, Rie Miura, Asami Kobayashi, Makito Mizunuma, Aisa Yamauchi, Masayuki Futagami, Hideki Mizunuma
Pages: 4933-4938
Published online on: 25 April 2017

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Article

Plasma T790M and HGF as potential predictive markers for EGFR-TKI re-challenge

Tomomi Nakamura, Naomi Watanabe, Akemi Sato, Kazutoshi Komiya, Hitomi Umeguchi, Toshiya Hosomi, Mitsuharu Hirai, Eisaburo Sueoka, Shinya Kimura, Naoko Sueoka‑Aragane
Pages: 4939-4946
Published online on: 24 April 2017

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Article

Sequential administration of XELOX and XELIRI is effective, feasible and well tolerated by patients with metastatic colorectal cancer

Taro Fukui, Koichi Suzuki, Kosuke Ichida, Yuji Takayama, Nao Kakizawa, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Masaaki Saito, Shingo Tsujinaka, Yasuyuki Miyakura, Toshiki Rikiyama
Pages: 4947-4952
Published online on: 26 April 2017

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Article

Comparison of hand-assisted laparoscopic surgery (HALS) and conventional laparotomy in patients with colorectal cancer: Final results from a single center

Takayuki Tajima, Masaya Mukai, Daiki Yokoyama, Shigeo Higami, Shuji Uda, Sayuri Hasegawa, Eiji Nomura, Sotaro Sadahiro, Seiei Yasuda, Hiroyasu Makuuchi
Pages: 4953-4958
Published online on: 13 April 2017

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Article

Treatment outcomes of concurrent hyperthermia and chemoradiotherapy for pancreatic cancer: Insights into the significance of hyperthermia treatment

Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Tsutomu Sato, Jiro Kawamori, Yoshiaki Tanaka
Pages: 4959-4964
Published online on: 21 April 2017

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Article

Comparative secretome of ovarian serous carcinoma: Gelsolin in the spotlight

Sandra Pierredon, Pascale Ribaux, Jean‑Christophe Tille, Patrick Petignat, Marie Cohen
Pages: 4965-4973
Published online on: 25 April 2017

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Article

Myricetin induces apoptosis and enhances chemosensitivity in ovarian cancer cells

Ai‑Wen Zheng, Ya‑Qing Chen, Ling‑Qin Zhao, Jian‑Guo Feng
Pages: 4974-4978
Published online on: 13 April 2017

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Article

Notable roles of EZH2 and DNMT1 in epigenetic dormancy of the SHP1 gene during the progression of chronic myeloid leukaemia

Jing Wang, Luoming Hua, Ming Guo, Lin Yang, Xiaojun Liu, Yanmeng Li, Xiaoyan Shang, Jianmin Luo
Pages: 4979-4985
Published online on: 19 April 2017

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MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS Retraction in /10.3892/ol.2026.15482

Yi Xiao, Taoran Deng, Changliang Su, Zhen Shang
Pages: 4986-4994
Published online on: 24 April 2017

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Article

Prostate cancer downregulated SIRP-α modulates apoptosis and proliferation through p38-MAPK/NF-κB/COX-2 signaling

Chen Yao, Gang Li, Ming Cai, Yeyong Qian, Liqin Wang, Li Xiao, Friedrich Thaiss, Bingyi Shi
Pages: 4995-5001
Published online on: 21 April 2017

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The clinicopathological and prognostic role of thrombocytosis in patients with cancer: A meta-analysis

Xiaojing Zhang, Zunfu Lv, Hua Yu, Jianqing Zhu
Pages: 5002-5008
Published online on: 20 April 2017

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Article

MicroRNA-10b inhibits proliferation, migration and invasion in cervical cancer cells via direct targeting of insulin-like growth factor-1 receptor

Ren Hou, Daixian Wang, Jian Lu
Pages: 5009-5015
Published online on: 13 April 2017

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Article

Effects of inflammatory factors including plasma tumor necrosis factor-α in the clinical treatment of acute respiratory distress syndrome

Shu Ran Huang, Ai Ying Ma, Yuan Liu, Yan Qu
Pages: 5016-5020
Published online on: 25 April 2017

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Article

microRNA-497 overexpression decreases proliferation, migration and invasion of human retinoblastoma cells via targeting vascular endothelial growth factor A

Jianjun Li, Yinghui Zhang, Xiuchao Wang, Ruibo Zhao
Pages: 5021-5027
Published online on: 24 April 2017

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Article

Combination of wogonin and sorafenib effectively kills human hepatocellular carcinoma cells through apoptosis potentiation and autophagy inhibition

Li‑Wen Rong, Rui‑Xue Wang, Xue‑Lian Zheng, Xu‑Qin Feng, Lei Zhang, Lin Zhang, Yong Lin, Zhi‑Ping Li, Xia Wang
Pages: 5028-5034
Published online on: 20 April 2017

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Correction Open Access

[Corrigendum] Vinflunine treatment in patients with metastatic urothelial cancer: A Nordic retrospective multicenter analysis

Karin Holmsten, Line Hammer Dohn, Niels Viggo Jensen, Carl‑Henrik Shah, Fredrik Jäderling, Helle Pappot, Anders Ullén
Pages: 5035-5035
Published online on: 24 April 2017

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

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Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

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Case Report Open Access

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Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

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Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

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Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
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Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
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Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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