1
|
Kallinowski F, Schlenger KH, Runkel S,
Kloes M, Stohrer M, Okunieff P and Vaupel P: Blood flow,
metabolism, cellular microenvironment, and growth rate of human
tumor xenografts. Cancer Res. 49:3759–3764. 1989.PubMed/NCBI
|
2
|
De Palma M and Naldini L: Role of
haematopoietic cells and endothelial progenitors in tumour
angiogenesis. Biochim Biophys Acta. 1766:159–166. 2006.PubMed/NCBI
|
3
|
Spring H, Schuler T, Arnold B, Hämmerling
GJ and Ganss R: Chemokines direct endothelial progenitors into
tumor neovessels. Proc Natl Acad Sci USA. 102:18111–18116. 2005.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Nolan DJ, Ciarrocchi A, Mellick AS, Jaggi
JS, Bambino K, Gupta S, Heikamp E, McDevitt MR, Scheinberg DA,
Benezra R and Mittal V: Bone marrow-derived endothelial progenitor
cells are a major determinant of nascent tumor neovascularization.
Genes Dev. 21:1546–1558. 2007. View Article : Google Scholar : PubMed/NCBI
|
5
|
Collet G, Skrzypek K, Grillon C, Matejuk
A, El Hafni-Rahbi B, Lamerant-Fayel N and Kieda C: Hypoxia control
to normalize pathologic angiogenesis: Potential role for
endothelial precursor cells and miRNAs regulation. Vascul
Pharmacol. 56:252–261. 2012. View Article : Google Scholar : PubMed/NCBI
|
6
|
Weidner N, Semple JP, Welch WR and Folkman
J: Tumor angiogenesis and metastasis-correlation in invasive breast
carcinoma. N Engl J Med. 324:1–8. 1991. View Article : Google Scholar : PubMed/NCBI
|
7
|
Macchiarini P, Fontanini G, Hardin MJ,
Squartini F and Angeletti CA: Relation of neovascularisation to
metastasis of non-small-cell lung cancer. Lancet. 340:145–146.
1992. View Article : Google Scholar : PubMed/NCBI
|
8
|
Weidner N, Carroll PR, Flax J, Blumenfeld
W and Folkman J: Tumor angiogenesis correlates with metastasis in
invasive prostate carcinoma. Am J Pathol. 143:401–409.
1993.PubMed/NCBI
|
9
|
Davidoff AM, Ng CY, Brown P, Leary MA,
Spurbeck WW, Zhou J, Horwitz E, Vanin EF and Nienhuis AW: Bone
marrow-derived cells contribute to tumor neovasculature and, when
modified to express an angiogenesis inhibitor, can restrict tumor
growth in mice. Clin Cancer Res. 7:2870–2879. 2001.PubMed/NCBI
|
10
|
Vajkoczy P, Blum S, Lamparter M,
Mailhammer R, Erber R, Engelhardt B, Vestweber D and Hatzopoulos
AK: Multistep nature of microvascular recruitment of ex
vivo-expanded embryonic endothelial progenitor cells during tumor
angiogenesis. J Exp Med. 197:1755–65. 2003. View Article : Google Scholar : PubMed/NCBI
|
11
|
Yu D, Sun X, Qiu Y, Zhou J, Wu Y, Zhuang
L, Chen J and Ding Y: Identification and clinical significance of
mobilized endothelial progenitor cells in tumor vasculogenesis of
hepatocellular carcinoma. Clin Cancer Res. 13:3814–3824. 2007.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Dome B, Hendrix MJ, Paku S, Tóvári J and
Tímár J: Alternative vascularization mechanisms in cancer:
Pathology and therapeutic implications. Am J Pathol. 170:1–15.
2007. View Article : Google Scholar : PubMed/NCBI
|
13
|
Kallinowski F and Vaupel P: pH
distributions in spontaneous and isotransplanted rat tumours. Br J
Cancer. 58:314–321. 1988. View Article : Google Scholar : PubMed/NCBI
|
14
|
Gerweck LE and Seetharaman K: Cellular pH
gradient in tumor versus normal tissue: Potential exploitation for
the treatment of cancer. Cancer Res. 56:1194–1198. 1996.PubMed/NCBI
|
15
|
Hjelmeland AB, Wu Q, Heddleston JM,
Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan
A and Rich JN: Acidic stress promotes a glioma stem cell phenotype.
Cell Death Differ. 18:829–840. 2011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Dietl K, Renner K, Dettmer K, Timischl B,
Eberhart K, Dorn C, Hellerbrand C, Kastenberger M, Kunz-Schughart
LA, Oefner PJ, et al: Lactic acid and acidification inhibit TNF
secretion and glycolysis of human monocytes. J Immunol.
184:1200–1209. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Kumar S, Reusch HP and Ladilov Y: Acidic
pre-conditioning suppresses apoptosis and increases expression of
Bcl-xL in coronary endothelial cells under simulated ischaemia. J
Cell Mol Med. 12:1584–1592. 2008. View Article : Google Scholar : PubMed/NCBI
|
18
|
Huang S, Peng L, Tang Y, Zhang L, Guo W,
Zou X and Peng X: Hypoxia of PC-3 prostate cancer cells enhances
migration and vasculogenesis in vitro of bone marrow-derived
endothelial progenitor cells by secretion of cytokines. Oncol Rep.
29:2369–2377. 2013. View Article : Google Scholar : PubMed/NCBI
|
19
|
Kumar S, Kasseckert S, Kostin S, Abdallah
Y, Schafer C, Kaminski A, Reusch HP, Piper HM, Steinhoff G and
Ladilov Y: Ischemic acidosis causes apoptosis in coronary
endothelial cells through activation of caspase-12. Cardiovasc Res.
73:172–180. 2007. View Article : Google Scholar : PubMed/NCBI
|
20
|
Ryschich E, Schmidt J, Hämmerling GJ, Klar
E and Ganss R: Transformation of the microvascular system during
multistage tumorigenesis. Int J Cancer. 97:719–725. 2002.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Ahn GO and Brown JM: Role of endothelial
progenitors and other bone marrow-derived cells in the development
of the tumor vasculature. Angiogenesis. 12:159–164. 2009.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Vaupel PW, Frinak S and Bicher HI:
Heterogeneous oxygen partial pressure and pH distribution in C3H
mouse mammary adenocarcinoma. Cancer Res. 41:2008–2013.
1981.PubMed/NCBI
|
23
|
D'Arcangelo D, Facchiano F, Barlucchi LM,
Melillo G, Illi B, Testolin L, Gaetano C and Capogrossi MC:
Acidosis inhibits endothelial cell apoptosis and function and
induces basic fibroblast growth factor and vascular endothelial
growth factor expression. Circ Res. 86:312–318. 2000. View Article : Google Scholar : PubMed/NCBI
|
24
|
Dairaghi DJ, Oldham ER, Bacon KB and
Schall TJ: Chemokine receptor CCR3 function is highly dependent on
local pH and ionic strength. J Biol Chem. 272:28206–28209. 1997.
View Article : Google Scholar : PubMed/NCBI
|
25
|
French AR, Tadaki DK, Niyogi SK and
Lauffenburger DA: Intracellular trafficking of epidermal growth
factor family ligands is directly influenced by the pH sensitivity
of the receptor/ligand interaction. J Biol Chem. 270:4334–4340.
1995. View Article : Google Scholar : PubMed/NCBI
|
26
|
Schmedtje JF Jr, Liu WL and Chen Y: pH is
critical to the regulation of expression of the beta 2-adrenergic
receptor gene in hypoxia. Biochim Biophys Acta. 1314:25–33. 1996.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Rofstad EK: Microenvironment-induced
cancer metastasis. Int J Radiat Biol. 76:589–605. 2000. View Article : Google Scholar : PubMed/NCBI
|
28
|
Martínez-Zaguilán R, Seftor EA, Seftor RE,
Chu YW, Gillies RJ and Hendrix MJ: Acidic pH enhances the invasive
behavior of human melanoma cells. Clin Exp Metastasis. 14:176–186.
1996. View Article : Google Scholar : PubMed/NCBI
|
29
|
Robey IF, Baggett BK, Kirkpatrick ND, Roe
DJ, Dosescu J, Sloane BF, Hashim AI, Morse DL, Raghunand N, Gatenby
RA and Gillies RJ: Bicarbonate increases tumor pH and inhibits
spontaneous metastases. Cancer Res. 69:2260–2268. 2009. View Article : Google Scholar : PubMed/NCBI
|
30
|
Cuvier C, Jang A and Hill RP: Exposure to
hypoxia, glucose starvation and acidosis: Effect on invasive
capacity of murine tumor cells and correlation with cathepsin (L +
B) secretion. Clin Exp Metastasis. 15:19–25. 1997. View Article : Google Scholar : PubMed/NCBI
|
31
|
Tomida A and Tsuruo T: Drug resistance
mediated by cellular stress response to the microenvironment of
solid tumors. Anticancer Drug Des. 14:169–177. 1999.PubMed/NCBI
|
32
|
Tannock IF and Rotin D: Acid pH in tumors
and its potential for therapeutic exploitation. Cancer Res.
49:4373–4384. 1989.PubMed/NCBI
|
33
|
Flacke JP, Kumar S, Kostin S, Reusch HP
and Ladilov Y: Acidic preconditioning protects endothelial cells
against apoptosis through p38- and Akt-dependent Bcl-xL
overexpression. Apoptosis. 14:90–96. 2009. View Article : Google Scholar : PubMed/NCBI
|
34
|
Putney LK and Barber DL: Na-H
exchange-dependent increase in intracellular pH times G2/M entry
and transition. J Biol Chem. 278:44645–44649. 2003. View Article : Google Scholar : PubMed/NCBI
|
35
|
Smallbone K, Maini PK and Gatenby RA:
Episodic, transient systemic acidosis delays evolution of the
malignant phenotype: Possible mechanism for cancer prevention by
increased physical activity. Biol Direct. 5:222010. View Article : Google Scholar : PubMed/NCBI
|
36
|
Burbridge MF, West DC, Atassi G and Tucker
GC: The effect of extracellular pH on angiogenesis in vitro.
Angiogenesis. 3:281–288. 1999. View Article : Google Scholar : PubMed/NCBI
|