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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2017 Volume 14 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Renin angiotensin system deregulation as renal cancer risk factor (Review)

Paweł Sobczuk, Cezary Szczylik, Camillo Porta, Anna M. Czarnecka
Pages: 5059-5068
Published online on: 25 August 2017

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Review

MicroRNAs, a subpopulation of regulators, are involved in breast cancer progression through regulating breast cancer stem cells (Review)

Xuemei Fan, Wei Chen, Ziyi Fu, Lihua Zeng, Yongmei Yin, Hongyan Yuan
Pages: 5069-5076
Published online on: 01 September 2017

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Review Open Access

Role of galectins in lung cancer (Review)

Wei‑An Chang, Ming‑Ju Tsai, Po‑Lin Kuo, Jen‑Yu Hung
Pages: 5077-5084
Published online on: 04 September 2017

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Review

Current status of submucosal tunneling endoscopic resection for gastrointestinal submucosal tumors originating from the muscularis propria layer (Review)

Yuyong Tan, Jirong Huo, Deliang Liu
Pages: 5085-5090
Published online on: 01 September 2017

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Review Open Access

Research progress on circadian clock genes in common abdominal malignant tumors (Review)

Sheng‑Li Yang, Quan‑Guang Ren, Lu Wen, Jian‑Li Hu, Heng‑Yi Wang
Pages: 5091-5098
Published online on: 31 August 2017

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Review

Role and underlying mechanisms of the interstitial protein periostin in the diagnosis and treatment of malignant tumors (Review)

Dong Ye, Zhi Sen Shen, Shi Jie Qiu, Qun Li, Guo Li Wang
Pages: 5099-5106
Published online on: 01 September 2017

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Review

Aberrant chromatin remodeling in gynecological cancer (Review)

Ryuichiro Okawa, Kouji Banno, Miho Iida, Megumi Yanokura, Takashi Takeda, Moito Iijima, Haruko Kunitomi‑Irie, Kanako Nakamura, Masataka Adachi, Kiyoko Umene, Yuya Nogami, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
Pages: 5107-5113
Published online on: 06 September 2017

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Review Open Access

Alternative splicing regulation in tumor necrosis factor‑mediated inflammation (Review)

Eduardo López‑Urrutia, Alma Campos‑Parra, Luis Alonso Herrera, Carlos Pérez‑Plasencia
Pages: 5114-5120
Published online on: 06 September 2017

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Article Open Access

MicroRNA‑193a‑3p inhibits cell proliferation in prostate cancer by targeting cyclin D1

Yunfu Liu, Xin Xu, Xianglai Xu, Shiqi Li, Zhen Liang, Zhenghui Hu, Jian Wu, Yi Zhu, Xiaodong Jin, Xiao Wang, Yiwei Lin, Hong Chen, Yeqing Mao, Jindan Luo, Xiangyi Zheng, Liping Xie
Pages: 5121-5128
Published online on: 01 September 2017

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Article Open Access

Effect of surgical margins on prognosis in aggressive fibromatosis: A single‑institutional analysis of 90 patients

Kamran Harati, Anais Jaenisch, Björn Behr, Ole Goertz, Ali Harati, Tobias Hirsch, Ingo Stricker, Marcus Lehnhardt, Adrien Daigeler
Pages: 5129-5134
Published online on: 01 September 2017

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Article Open Access

Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL‑XL

Jun‑Hai Tang, Guo‑Hao Huang, Ke‑Jie Mou, Eric Erquan Zhang, Ningning Li, Lei Du, Xiao‑Peng Zhu, Ling Chen, Hui Yang, Ke‑Bin Zhang, Sheng‑Qing Lv
Pages: 5135-5144
Published online on: 28 August 2017

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Article Open Access

Expression profile of Oct‑4 lung cancer‑specific marker prior and subsequent to a salirasib treatment regime

Xiang Ao, Jie Zhou, Hong Ling Liang, Ming Jiang, Hong Sheng Li
Pages: 5145-5148
Published online on: 01 September 2017

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Article Open Access

The role of LASS2 in regulating bladder cancer cell tumorigenicity in a nude mouse model

Yujin Chen, Haifeng Wang, Tao Xiong, Renchao Zou, Zhaoran Tang, Jiansong Wang
Pages: 5149-5156
Published online on: 04 September 2017

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Article Open Access

Therapeutic effects of protein kinase N3 small interfering RNA and doxorubicin combination therapy on liver and lung metastases

Yoshiyuki Hattori, Takuto Kikuchi, Mari Nakamura, Kei‑Ichi Ozaki, Hiraku Onishi
Pages: 5157-5166
Published online on: 25 August 2017

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Case Report Open Access

Large Wolffian adnexal tumor of the ovary: A case report and literature review

Ya‑Qiong Du, Shu‑Zheng Song, Xiao‑Chun Ni, Ju‑Gang Wu, Shou‑Lian Wang, Bo‑Jian Jiang, Ji‑Wei Yu
Pages: 5167-5170
Published online on: 31 August 2017

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Article Open Access

Coexistence of p210BCR‑ABL and CBFβ‑MYH11 fusion genes in myeloid leukemia: A report of 4 cases

Yuan‑Yuan Wang, Wen‑Jing Ding, Feng Jiang, Zi‑Xing Chen, Jian‑Nong Cen, Xiao‑Fei Qi, Jian‑Ying Liang, Dan‑Dan Liu, Jin‑Lan Pan, Su‑Ning Chen
Pages: 5171-5178
Published online on: 24 August 2017

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Article Open Access

Detection of somatic mutations in the mitochondrial DNA control region D‑loop in brain tumors: The first report in Malaysian patients

Abdul Aziz Mohamed Yusoff, Khairol Naaim Mohd Nasir, Khalilah Haris, Siti Zulaikha Nashwa Mohd Khair, Abdul Rahman Izaini Abdul Ghani, Zamzuri Idris, Jafri Malin Abdullah
Pages: 5179-5188
Published online on: 28 August 2017

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Article Open Access

Synergistic inhibitory effects of an engineered antibody‑like molecule ATF‑Fc and trastuzumab on tumor growth and invasion in a human breast cancer xenograft mouse model

Hongwei Zhou, Hongwei Wang, Guangyuan Yu, Zhihong Wang, Xi Zheng, Haifeng Duan, Junzhong Sun
Pages: 5189-5196
Published online on: 06 September 2017

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Case Report Open Access

POEMS syndrome presentation with progressive weakness in upper and lower limbs: A case report

Chuang‑Jie Cao, Cheng‑Yun Dou, Ke‑Hua Zhou, Jin‑Bo Liu, Hong Lai
Pages: 5197-5202
Published online on: 06 September 2017

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Article Open Access

Identification of potential therapeutic targets for gliomas by bioinformatics analysis

Ke Ma, Zhihua Cheng, Liqun Sun, Haibo Li
Pages: 5203-5210
Published online on: 28 August 2017

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Article Open Access

Azithromycin attenuates acute radiation‑induced lung injury in mice

Fei Tang, Rui Li, Jianxin Xue, Jie Lan, He Xu, Yongmei Liu, Lin Zhou, You Lu
Pages: 5211-5220
Published online on: 24 August 2017

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Article Open Access

Lack of microsatellite instability in gastrointestinal stromal tumors

Nathália C. Campanella, Cristovam Scapulatempo‑Neto, Lucas Faria Abrahão‑Machado, Antônio Talvane Torres De Oliveira, Gustavo N. Berardinelli, Denise Peixoto Guimarães, Rui M. Reis
Pages: 5221-5228
Published online on: 04 September 2017

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Article Open Access

Lysosome‑associated protein transmembrane4β is involved in multidrug resistance processes of colorectal cancer

Yue‑Nan Huang, Xin Guo, Liu‑Ping You, Chun‑Jing Wang, Jia‑Qi Liu, Yun‑Long Li
Pages: 5229-5234
Published online on: 06 September 2017

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Article Open Access

Lumican expression in gastric cancer and its association with biological behavior and prognosis

Li Chen, Yuxin Zhang, Yanjiao Zuo, Fei Ma, Hongjiang Song
Pages: 5235-5240
Published online on: 28 August 2017

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Article Open Access

Treatment of osteosarcoma around the knee in skeletally immature patients

Weitao Yao, Qiqing Cai, Jiaqiang Wang, Songtao Gao
Pages: 5241-5248
Published online on: 06 September 2017

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Article Open Access

Germline cytotoxic lymphocytes defective mutations in Chinese patients with lymphoma

Xue Chen, Yang Zhang, Fang Wang, Mangju Wang, Wen Teng, Yuehui Lin, Xiangping Han, Fangyuan Jin, Yuanli Xu, Panxiang Cao, Jiancheng Fang, Ping Zhu, Chunrong Tong, Hongxing Liu
Pages: 5249-5256
Published online on: 06 September 2017

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Article Open Access

Methylation of 14‑3‑3σ gene and prognostic significance of 14‑3‑3σ expression in non‑small cell lung cancer

Pritsana Raungrut, Pingpond Petjaroen, Sarayut Lucien Geater, Warangkana Keeratichananont, Monlika Phukaoloun, Supaporn Suwiwat, Paramee Thongsuksai
Pages: 5257-5264
Published online on: 04 September 2017

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Article Open Access

Retrospective analysis of the association between human epidermal growth factor receptor 2 amplification and chromosome enumeration probe 17 status in patients with breast cancer

Xiaoyu Hu, Yanan Li, Dong Yuan, Ruohan Li, Lingquan Kong, Hongyuan Li, Zhu Yang, Qiubo Yu
Pages: 5265-5270
Published online on: 06 September 2017

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Article Open Access

Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27

Jianbing Niu, Xiulian Zhao, Qingsheng Liu, Jinsan Yang
Pages: 5271-5278
Published online on: 01 September 2017

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Article Open Access

Mismatched intratumoral distribution of [18F] fluorodeoxyglucose and 3'‑deoxy‑3'‑[18F] fluorothymidine in patients with lung cancer Corrigendum in /10.3892/ol.2018.8756

Xiangcheng Wang, Yulin He, Weina Zhou, Xia Bai, Yiwei Wu, Xuemei Wang, Xiao‑Feng Li
Pages: 5279-5284
Published online on: 28 August 2017

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Article Open Access

Co‑activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer

Kimberly M. Arnold, Ryan T. Pohlig, Jennifer Sims‑Mourtada
Pages: 5285-5292
Published online on: 01 September 2017

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Article Open Access

Methylation and expression of RECK, P53 and RUNX genes in patients with esophageal cancer

Yanrong Lu, Baerxiaguli Zabihula, Waresijiang Yibulayin, Xiang Liu
Pages: 5293-5298
Published online on: 31 August 2017

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Article Open Access

Application of spontaneously closing cannula ileostomy in laparoscopic anterior resection of rectal cancer

Dong Chen, Huiying Zhao, Qiang Huang, Xiangming Xu, Xiaofei Cheng, Bingxin Ke, Danyang Wang, Hanju Hua, Jiahe Xu, Jianjiang Lin, Feng Ye
Pages: 5299-5306
Published online on: 01 September 2017

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Article Open Access

Fangchinoline inhibits migration and causes apoptosis of human breast cancer MDA-MB-231 cells

Binggao Wang, Zhibo Xing, Fengmei Wang, Xinyan Yuan, Yanhui Zhang
Pages: 5307-5312
Published online on: 25 August 2017

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Article Open Access

The prognostic significance of tumor lymphangiogenesis and lymphatic vessel density in endometrioid carcinoma of the uterine corpus

Mika Sakaki, Masanori Yasuda, Mitsutake Yano, Yoshiya Goto, Masaru Nakamura, Hidekazu Kayano, Kosei Hasegawa
Pages: 5313-5318
Published online on: 04 September 2017

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Article Open Access

Expression of circadian clock genes in human colorectal adenoma and carcinoma

Tomoyuki Momma, Hirokazu Okayama, Masaru Saitou, Hidekazu Sugeno, Nobuhiro Yoshimoto, Yuji Takebayashi, Shinji Ohki, Seiichi Takenoshita
Pages: 5319-5325
Published online on: 04 September 2017

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Article Open Access

Inhibitory effect of carboplatin in combination with bevacizumab on human retinoblastoma in an in vitro and in vivo model

Qi Zhang, Yong Cheng, Lvzhen Huang, Yujing Bai, Jianhong Liang, Xiaoxin Li
Pages: 5326-5332
Published online on: 25 August 2017

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Article Open Access

Endocan silencing induces programmed cell death in hepatocarcinoma

Jinghui Yang, Shihou Sheng, Qiwei Yang, Li Li, Shaoyou Qin, Shan Yu, Xuewen Zhang
Pages: 5333-5339
Published online on: 31 August 2017

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Article Open Access

Negative correlation between X‑linked inhibitors of apoptosis and second mitochondria‑derived activator of caspase expression levels in cervical carcinoma and cervical intraepithelial neoplasia

Xue‑Jing Jin, Ping‑Sheng Cai, Shu‑Pin Zhu, Li‑Jie Wang, Hua Zhu
Pages: 5340-5346
Published online on: 04 September 2017

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Article Open Access

Synergistic anti‑proliferative and pro‑apoptotic activities of 5F and cisplatin in human non‑small cell lung cancer NCI‑H23 cells

Yuchan Li, Wende Li, Wusheng Deng, Yuhong Gan, Kefeng Wu, Jie Sun
Pages: 5347-5353
Published online on: 28 August 2017

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Article Open Access

Lentivirus‑mediated RNA interference inhibits the tumorigenicity of cluster of differentiation 44+ tumor cells in hypopharyngeal cancer

Chenling Shen, Bin Ye, Haixia Hu, Chen Nie, Yan Ma, Jingrong Lv, Hao Wu, Mingliang Xiang
Pages: 5354-5360
Published online on: 28 August 2017

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Article Open Access

Screening of potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles

Rui Zhao, Yao Wang, Muchun Zhang, Xinquan Gu, Weihua Wang, Jiufeng Tan, Xin Wei, Ning Jin
Pages: 5361-5369
Published online on: 04 September 2017

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Article Open Access

Clinicopathological features and prognostic factors in angiosarcoma: A retrospective analysis of 200 patients from a single Chinese medical institute

Lei Wang, I Weng Lao, Lin Yu, Jian Wang
Pages: 5370-5378
Published online on: 06 September 2017

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Article Open Access

Elevated FKBP52 expression indicates a poor outcome in patients with breast cancer

Chaoqun Hong, Ting Li, Fan Zhang, Xiao Wu, Xipeng Chen, Xiaojiang Cui, Guojun Zhang, Yukun Cui
Pages: 5379-5385
Published online on: 25 August 2017

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Article Open Access

Co‑expression and significance of Dok2 and Ras p21 protein activator 1 in breast cancer

Jiangrong Huang, Xiaochun Peng, Kun Zhang, Chunyan Li, Bo Su, Yanxiang Zhang, Wangui Yu
Pages: 5386-5392
Published online on: 28 August 2017

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Article Open Access

Bioinformatics analysis of SRSF1‑controlled gene networks in colorectal cancer

Junxiu Sheng, Jinyao Zhao, Qiuhong Xu, Linlin Wang, Wenjing Zhang, Yang Zhang
Pages: 5393-5399
Published online on: 06 September 2017

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Article Open Access

Astaxanthin inhibits gemcitabine‑resistant human pancreatic cancer progression through EMT inhibition and gemcitabine resensitization

Tao Yan, Hai‑Ying Li, Jian‑Song Wu, Qiang Niu, Wei‑Hong Duan, Qing‑Zeng Han, Wang‑Ming Ji, Tao Zhang, Wei Lv
Pages: 5400-5408
Published online on: 28 August 2017

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Article Open Access

Combined aspirin and apatinib treatment suppresses gastric cancer cell proliferation

Wei Zhang, Yongsheng Tan, Heping Ma
Pages: 5409-5417
Published online on: 31 August 2017

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Article Open Access

Quantitative analysis of permeability for glioma grading using dynamic contrast‑enhanced magnetic resonance imaging

Ming Zhao, Li‑Li Guo, Ning Huang, Qiong Wu, Li Zhou, Hui Zhao, Jing Zhang, Kuang Fu
Pages: 5418-5426
Published online on: 06 September 2017

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Article Open Access

Identification of miRNA and genes involving in osteosarcoma by comprehensive analysis of microRNA and copy number variation data

Tao Luo, Xiangli Yi, Wei Si
Pages: 5427-5433
Published online on: 28 August 2017

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Article Open Access

Impact of tumoral carbonic anhydrase IX and Ki‑67 expression on survival in oral squamous cell carcinoma patients

Nigel T. Brockton, Pawadee Lohavanichbutr, Emeka K. Enwere, Melissa P. Upton, Elizabeth N. Kornaga, Steven C. Nakoneshny, Pinaki Bose, Chu Chen, Joseph C. Dort
Pages: 5434-5442
Published online on: 25 August 2017

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Article Open Access

ASA404, a vascular disrupting agent, as an experimental treatment approach for brain tumors

Oliver Bähr, Stefanie Gross, Patrick N. Harter, Elmar Kirches, Christian Mawrin, Joachim P. Steinbach, Michel Mittelbronn
Pages: 5443-5451
Published online on: 28 August 2017

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Article Open Access

Correlation of MMP-9 and p53 protein expression with prognosis in metastatic spinal tumor of lung cancer

Shuquan Zhang, Minfei Wu, Yi Zhao, Rui Gu, Chuangang Peng, Jiabei Liu, Qingsan Zhu, Ye Li
Pages: 5452-5456
Published online on: 05 September 2017

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Article Open Access

Mammalian sterile 20‑like kinase 1 expression and its prognostic significance in patients with breast cancer

Xiao‑Yan Lin, Feng‑Feng Cai, Ming‑Hong Wang, Xin Pan, Fang Wang, Lu Cai, Rong‑Rong Cui, Su Chen, Ewelina Biskup
Pages: 5457-5463
Published online on: 28 August 2017

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Article Open Access

Classification and survival prediction for early‑stage lung adenocarcinoma and squamous cell carcinoma patients

Suyan Tian
Pages: 5464-5470
Published online on: 28 August 2017

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Article Open Access

Stereolithographic model‑assisted reconstruction of the mandibular condyle with a vascularized fibular flap following hemimandibulectomy: Evaluation of morphological and functional outcomes

Hitoshi Yoshimura, Shinpei Matsuda, Seigo Ohba, Yoshiki Minegishi, Kunihiro Nakai, Shigeharu Fujieda, Kazuo Sano
Pages: 5471-5483
Published online on: 07 September 2017

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Article

Role of cytochrome P450 2J2 on cell proliferation and resistance to an anticancer agent in hepatocellular carcinoma HepG2 cells

Geun Hye Hwang, So Mi Park, Ho Jae Han, Kyoung Min Baek, Joong Sun Kim, Woochul Chang, Ho Jin Lee, Seung Pil Yun, Jung Min Ryu, Min Young Lee
Pages: 5484-5490
Published online on: 28 August 2017

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Article

Expression and significance of secreted protein acidic and rich in cysteine in human osteosarcoma

Yongkun Yang, Xiaohui Niu, Weifeng Liu, Hairong Xu
Pages: 5491-5496
Published online on: 01 September 2017

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Article

Potential role of indoleamine 2,3‑dioxygenase in primary biliary cirrhosis

Kashif Asghar, John Brain, Jeremy M. Palmer, Stephen Douglass, Fatmah M. A. Naemi, Graeme O'Boyle, John Kirby, Simi Ali
Pages: 5497-5504
Published online on: 28 August 2017

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Article

Immunohistochemical profile and prognostic significance in primary central nervous system lymphoma: Analysis of 89 cases

Jing Liu, Yaming Wang, Yuantao Liu, Zhe Liu, Qu Cui, Nan Ji, Shengjun Sun, Bingxu Wang, Yajie Wang, Xuefei Sun, Yuanbo Liu
Pages: 5505-5512
Published online on: 06 September 2017

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Article

Blocking integrin β1 decreases adhesion in chemoresistant urothelial cancer cell lines

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Helicobacter pylori modulates cyclooxygenase‑2 and 15‑hydroxy prostaglandin dehydrogenase in gastric cancer

Jianqiu Zhao, Shujun Wen, Xingfen Wang, Zhiguang Zhang
Pages: 5519-5525
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Klotho expression is correlated to molecules associated with epithelial‑mesenchymal transition in lung squamous cell carcinoma

Takayuki Ibi, Jitsuo Usuda, Tatsuya Inoue, Akira Sato, Kyoshiro Takegahara
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MicroRNA profiling and bioinformatics analyses reveal the potential roles of microRNAs in chordoma

Kangwu Chen, Hao Chen, Kai Zhang, Siwei Sun, Jianqiang Mo, Jian Lu, Zhonglai Qian, Huilin Yang
Pages: 5533-5539
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Pteisolic acid G, a novel ent‑kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells

Shuangli Qiu, Xin Wu, Hongbo Liao, Xiaobin Zeng, Senwang Zhang, Xiaofen Lu, Xiaohong He, Xiaoqi Zhang, Wencai Ye, Hua Wu, Xiaohui Zhu
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Article

Function of the macrophage‑capping protein in colorectal carcinoma

Wei Wu, Jingdi Chen, Qianshan Ding, Sheng Yang, Jianping Wang, Honggang Yu, Jun Lin
Pages: 5549-5555
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LncRNA UCA1 promotes the invasion and EMT of bladder cancer cells by regulating the miR‑143/HMGB1 pathway

Junhua Luo, Jing Chen, Hang Li, Yu Yang, Haichao Yun, Shangqi Yang, Xiangming Mao
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Aviscumine, a recombinant ribosomal inhibitor, increases the antitumor activity of natural killer cells

Gabriele Gamerith, Arno Amann, Bettina Schenk, Thomas Auer, Hans Lentzen, Dirk O. Mügge, Katharina M. Cima, Judith Löffler‑Ragg, Wolfgang Hilbe, Heinz Zwierzina
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Hesperidin inhibits ovarian cancer cell viability through endoplasmic reticulum stress signaling pathways

Jun Zhao, Yali Li, Jinfang Gao, Yinshan De
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Article

Adenine causes cell cycle arrest and autophagy of chronic myelogenous leukemia K562 cells via AMP-activated protein kinase signaling

San-Yuan Chen, Chun-Hsiang Lin, Jiun-Tsai Lin, Yi-Fang Cheng, Han-Min Chen, Shao-Hsuan Kao
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Article

Curcumin inhibits MCF‑7 cells by modulating the NF‑κB signaling pathway

Jun‑Li Liu, Yan‑Yan Pan, Ou Chen, Yun Luan, Xia Xue, Jing‑Jie Zhao, Ling Liu, Hong‑Ying Jia
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Puerarin induces cell apoptosis in human chondrosarcoma cell line SW1353 via inhibition of the PI3K/Akt signaling pathway

Li Huang, Junqing Cao, Lan Cao, Ling Gao, Ying Yang, Li Xu
Pages: 5585-5590
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Overexpression of tumor suppressor gene ZNF750 inhibits oral squamous cell carcinoma metastasis

Hongli Yang, Li Pan, Cong Xu, Yingxin Zhang, Keyi Li, Shuangfeng Chen, Bin Zhang, Zhijun Liu, Le‑Xin Wang, Haiying Chen
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Zoledronic acid sensitizes rhabdomyosarcoma cells to cytolysis mediated by human γδ T cells

Ling‑Ling Sun, Zheng‑Liang Zhang, Ying‑Jun Li, Sheng‑Dong Wang, Heng‑Yuan Li, Bing‑Hao Li, Ting Zhu, Zhao‑Ming Ye
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The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells

Patricia Adamo, Sean Porazinski, Shavanthi Rajatileka, Samantha Jumbe, Rachel Hagen, Man‑Kim Cheung, Ian Wilson, Michael R. Ladomery
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Article

Predictors of EGFR mutation and factors associated with clinical tumor stage at diagnosis: Experience of the INSIGHT study in Poland

Rodryg Ramlau, Paweł Krawczyk, Rafał Dziadziuszko, Izabela Chmielewska, Janusz Milanowski, Włodzimierz Olszewski, Katarzyna Stencel, Katarzyna Ramlau‑Piątek, Agnieszka Segiet, Michał Skroński, Jacek Grudny, Joanna Chorostowska‑Wynimko
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Lin‑Hui Hu, Lian‑Fang Pu, Dong‑Dong Yang, Cui Zhang, Hui‑Ping Wang, Yang‑Yang Ding, Man‑Man Li, Zhi‑Min Zhai, Shudao Xiong
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miR‑514a‑3p functions as a tumor suppressor in renal cell carcinoma

Lu Jin, Yifan Li, Zeng Zhang, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yun Chen, Yongqing Lai
Pages: 5624-5630
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Article

Upregulation of microRNA‑18b induces phosphatase and tensin homolog to accelerate the migration and invasion abilities of ovarian cancer

Xiaofang Han, Yan Zhang, Dong Wang, Xinyun Fu, Meiqing Li, Aiming Wang
Pages: 5631-5637
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Article

Exogenous DKK‑3/REIC inhibits Wnt/β‑catenin signaling and cell proliferation in human kidney cancer KPK1

Jiaqi Xu, Takuya Sadahira, Rie Kinoshita, Shun‑Ai Li, Peng Huang, Koichiro Wada, Motoo Araki, Kazuhiko Ochiai, Hirofumi Noguchi, Masakiyo Sakaguchi, Yasutomo Nasu, Masami Watanabe
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Article

Similarity in the functions of HIF‑1α and HIF‑2α proteins in cervical cancer cells

Lixia Jiang, Shaohua Shi, Qiaofa Shi, Huijuan Zhang, Rong Hu, Meizhen Wang
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Article

Role of 5‑Aza‑CdR in mitomycin‑C chemosensitivity of T24 bladder cancer cells

Hui‑Hui Zhang, Bo Huang, You‑Han Cao, Qing Li , Han‑Feng Xu
Pages: 5652-5656
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Article

Value of endorectal ultrasonography in measuring the extent of mesorectal invasion and substaging of T3 stage rectal cancer

Guangxi Zhong, Yi Xiao, Weixun Zhou, Weidong Pan, Qingli Zhu, Jing Zhang, Yuxin Jiang
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Correction Open Access

[Corrigendum] A novel t(9;22;11) translocation involving 11q24 in a patient with chronic myeloid leukemia: A case report

Jaehyeon Lee, Dal Sik Kim, Hye Soo Lee, Sam Im Choi, Yong Gon Cho
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Immune‑related adverse events during anticancer immunotherapy: Pathogenesis and management (Review)

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Advances in targeting the transforming growth factor β1 signaling pathway in lung cancer radiotherapy (Review)

Zhonghua Lu, Yiting Tang, Judong Luo, Shuyu Zhang, Xifa Zhou, Lei Fu
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Inhibition of DMH‑DSS‑induced colorectal cancer by liposomal bovine lactoferrin in rats

Yuka Sugihara, Xiaoxu Zuo, Takashi Takata, Shengjian Jin, Mutumi Miyauti, Atusi Isikado, Hiromichi Imanaka, Masaaki Tatsuka, Guangying Qi, Fumio Shimamoto
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Acidic stress induces apoptosis and inhibits angiogenesis in human bone marrow‑derived endothelial progenitor cells

Shuai Huang, Peiheng He, Dongliang Xu, Jinglei Li, Xinsheng Peng, Yubo Tang
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miR‑214 targets the PTEN‑mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer

Jing Liu, Weiyan Chen, Haiyan Zhang, Ting Liu, Lin Zhao
Pages: 5711-5718
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Shizhen Zhang, Rui Lei, Jingjing Wu, Jinlan Shan, Zujian Hu, Lirong Chen, Xingchang Ren, Lifang Yao, Jian Wang, Xiaochen Wang
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High expression of monocarboxylate transporter 4 predicts poor prognosis in patients with lung adenocarcinoma

Yushu Ruan, Fanjun Zeng, Zhiqiang Cheng, Xianda Zhao, Pin Fu, Honglei Chen
Pages: 5727-5734
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EZH2 and histone deacetylase inhibitors induce apoptosis in triple negative breast cancer cells by differentially increasing H3 Lys27 acetylation in the BIM gene promoter and enhancers

Julia P. Huang, Kun Ling
Pages: 5735-5742
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Distribution of uridine diphosphate glucuronosyltransferase 1A polymorphisms and their role in irinotecan‑induced toxicity in patients with cancer

Yang Wang, Cuihua Yi, Yawei Wang, Hui Li, Bei Li, Dan Wang, Jintong Du, Lian Liu, Xiuwen Wang
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Dongwen Zhang, Aixia Xu
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RASSF1A and SIRT6 in non-small cell lung cancer: Relationship with clinical outcome

Tao Chen, Zhaojun Sun, Fengling Liu, Qiang Wang
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A novel method to identify differential pathways in uterine leiomyomata based on network strategy

Hui‑Ling Wang, Jing Liu, Zhao‑Min Qin
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Nuclear paraspeckle assembly transcript 1 promotes the metastasis and epithelial‑mesenchymal transition of hepatoblastoma cells by inhibiting miR‑129‑5p

Ming‑Cui Fu, Li‑Qun Yuan, Ting Zhang, Xiang‑Ming Yan, Yun Zhou, Hong‑Liang Xia, Yi Wu, Li‑Xiao Xu, Xu Cao, Jian Wang
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Brain metastatic alveolar soft‑part sarcoma: Clinicopathological profiles, management and outcomes

Xiaogang Tao, Zonggang Hou, Zhen Wu, Shuyu Hao, Baiyun Liu
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Shoko Gamoh, Hironori Akiyama, Chisato Furukawa, Yuki Matsushima, Tomio Iseki, Masahiro Wato, Akio Tanaka, Shosuke Morita, Kimishige Shimizutani
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Prognostic value of copper transporter 1 expression in patients with clear cell renal cell carcinoma

Yu Xia, Li Liu, Qi Bai, Qilai Long, Jiajun Wang, Wei Xi, Jiejie Xu, Jianming Guo
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Analysis of imaging characteristics of primary malignant bone tumors in children

Yingwei Sun, Xueyong Liu, Shinong Pan, Chunbo Deng, Xiaohan Li, Qiyong Guo
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Aberrant expression of CD133 and CD82 in patients with pediatric acute lymphoblastic leukemia and the clinical significance

Hongyan Ji, Li Chen, Yunpeng Dai, Xiaojun Sun, Xiuli Li, Qi Wang, Daoxin Ma, Dongdong Du, Ping Zhao, Yulin Wang
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Knockdown of FUSE binding protein 1 enhances the sensitivity of epithelial ovarian cancer cells to carboplatin

Jinli Zhang, Xifeng Xiong, Xing Hua, Wenjuan Cao, Shengnan Qin, Libing Dai, Peihong Liang, Huiling Zhang, Zhihe Liu
Pages: 5819-5824
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Correlation between the presence of circulating tumor cells and the pathologic type and staging of non-small cell lung cancer during the early postoperative period

Zhanqiang Xie, Xiaotian Gao, Keluo Cheng, Lishuang Yu
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Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation Corrigendum in /10.3892/ol.2025.15101

Lina Qiao, Jianbao Zheng, Xianzhen Jin, Guangbing Wei, Guanghui Wang, Xuejun Sun, Xuqi Li
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Functional analysis of BRCT missense mutations in BRCA1‑mutated Chinese Han familial breast cancer

Hong Zhang, Linsen Li, Yuxia Wang, C. Cameron Yin, Yuntao Xie, Xijuan Liu, Huirong Ding, Zhihua Tian, Jing Shen, Long He, Miaoran Xia, Xi Ma, Lina Wu
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MicroRNA‑10b expression in node‑negative breast cancer‑correlation with metastasis and angiogenesis

Xia Liu, Yong Guan, Li Wang, Yun Niu
Pages: 5845-5852
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Grape seed proanthocyanidins induce mitochondrial pathway‑mediated apoptosis in human colorectal carcinoma cells

Chen Zhang, Weili Chen, Xuhao Zhang, Yanbing Zheng, Fengli Yu, Yulong Liu, Yi Wang
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Chest wall-parallel vs. conventional subclavian venous catheterization in cancer chemotherapy: A comparison of complication rates

Libo Li, Hang Li, Linli Xu, Lei Song
Pages: 5861-5864
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The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis

Hai Li, Zhenwei Qiu, Feng Li, Chunlei Wang
Pages: 5865-5870
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PAX8 is a potential marker for the diagnosis of primary epithelial ovarian cancer

Hong‑Juan Chai, Qing Ren, Qin Fan, Liu Ye, Guang‑Ye Du, Hua‑Wen Du, Wei Xu, Yue Li, Lan Zhang, Zhong‑Ping Cheng
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SPARC inhibits breast cancer bone metastasis and may be a clinical therapeutic target

Jingjing Ma, Sheng Gao, Xiju Xie, Erhu Sun, Min Zhang, Qian Zhou, Cheng Lu
Pages: 5876-5882
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High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis

Ying‑Yu Ma, Yuancheng Zhang, Xiao‑Zhou Mou, Zheng‑Chuang Liu, Guo‑Qing Ru, Erguang Li
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CD44+/CD24‑ phenotype predicts a poor prognosis in triple‑negative breast cancer

Hui Wang, Li Wang, Ying Song, Shuhuai Wang, Xu Huang, Qijia Xuan, Xinmei Kang, Qingyuan Zhang
Pages: 5890-5898
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T‑cell immunoglobulin mucin‑3 as a potential inducer of the epithelial‑mesenchymal transition in hepatocellular carcinoma

Huapeng Lin, Bin Yang, Mujian Teng
Pages: 5899-5905
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Effect of siRNA‑mediated gene silencing of transketolase on A549 lung cancer cells

Huan Lu, Huili Zhu
Pages: 5906-5912
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Silencing of semaphorin 3C suppresses cell proliferation and migration in MCF‑7 breast cancer cells

Xiaofang Zhu, Xiangjian Zhang, Zhiqiang Ye, Yizuo Chen, Lin Lv, Xiaohua Zhang, Hongye Hu
Pages: 5913-5917
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Low‑dose valproic acid with low‑dose gemcitabine augments MHC class I‑related chain A/B expression without inducing the release of soluble MHC class I‑related chain A/B

Tomoharu Miyashita, Kenji Miki, Takashi Kamigaki, Isamu Makino, Hidehiro Tajima, Shinichi Nakanuma, Hironori Hayashi, Hiroyuki Takamura, Sachio Fushida, Ali K. Ahmed, John W. Harmon, Tetsuo Ohta
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Intron‑specific shRNA‑mediated downregulation of survivin and promotion of apoptosis in HeLa cells

Yue‑Li Wang, Xin Shao, Fa Wang, Liang Zeng, Liang Hu, Shi‑Quan Cui, Gan Hou, Di‑Nan Huang
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Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma

Tingting Chen, Lan Zhou, Hua Li, Yuan Tian, Junqin Li, Lihua Dong, Yuhua Zhao, Dapeng Wei
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Squamous cell transformation and EGFR T790M mutation as acquired resistance mechanisms in a patient with lung adenocarcinoma treated with a tyrosine kinase inhibitor: A case report

Rossella Bruno, Agnese Proietti, Greta Alì, Gianfranco Puppo, Alessandro Ribechini, Antonio Chella, Gabriella Fontanini
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Reduced miR‑125a levels associated with poor survival of patients with hepatocellular cancer

Gaixia Lu, Yushui Ma, Chengyou Jia, Huiqiong Yang, Ruting Xie, Pei Luo, Li Chai, Haidong Cai, Mingxiang Cai, Zhongwei Lv, Xianling Cong, Da Fu
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Inhibition of cyclooxygenase‑2 sensitizes lung cancer cells to radiation‑induced apoptosis Corrigendum in /10.3892/ol.2019.10268

Zhi‑Qiang Han, Hongwei Liao, Feng Shi, Xiao‑Ping Chen, Hua‑Cheng Hu, Ming‑Qing Tian, Li‑Hua Wang, Songmin Ying
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Higher expression level of tyrosine kinase‑like orphan receptor 2 and Wnt member 5a in papillary thyroid carcinoma is associated with poor prognosis

Liang Chen, Lianmei Zhao, Mingjian Ding, Meng Yang, Wenhua Yang, Guozhong Cui, Baoen Shan
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Upregulation of TCTP is associated with cholangiocarcinoma progression and metastasis

Nattaporn Phanthaphol, Anchalee Techasen, Watcharin Loilome, Suyanee Thongchot, Raynoo Thanan, Sakkarn Sungkhamanon, Narong Khuntikeo, Puangrat Yongvanit, Nisana Namwat
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Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome

Radmila Lemstrova, Veronika Brynychova, David J. Hughes, Viktor Hlavac, Pavel Dvorak, Joanne E. Doherty, Helena A. Murray, Martin Crockard, Martin Oliverius, Jan Hlavsa, Eva Honsova, Jan Mazanec, Zdenek Kala, Martin Lovecek, Roman Havlik, Jiri Ehrmann, Ondrej Strouhal, Pavel Soucek, Bohuslav Melichar, Beatrice Mohelnikova-Duchonova
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Biochanin A induces anticancer effects in SK‑Mel‑28 human malignant melanoma cells via induction of apoptosis, inhibition of cell invasion and modulation of NF‑κB and MAPK signaling pathways Retraction in /10.3892/ol.2021.12724

Peng Xiao, Bowen Zheng, Jiaming Sun, Jia Yang
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MicroRNA‑10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway

Kongliang Ke, Tingting Lou
Pages: 5994-6000
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Selection of reference genes for gene expression studies in human bladder cancer using SYBR‑Green quantitative polymerase chain reaction Corrigendum in /10.3892/ol.2022.13205

Chuanxia Zhang, Yong Qiang Wang, Guangyi Jin, Song Wu, Jun Cui, Rong‑Fu Wang
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CD109 expression is upregulated in penile squamous cell carcinoma

Fengyun Dong, Jin Wang, Yinghua Xu, Zuowang Cheng, Xiaocui Chen, Yifan Wang, Ju Liu
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Downregulation of microRNA‑301a inhibited proliferation, migration and invasion of non‑small cell lung cancer by directly targeting DLC1

Zhuyu Wu, Yaojun Li, Guojun Zhang
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Expression of the cytoskeleton regulatory protein Mena in human gastric carcinoma and its prognostic significance

Lihua Xu, Huo Tan, Ruiming Liu, Qungai Huang, Nana Zhang, Xi Li, Jiani Wang
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Eupatolide inhibits the TGF‑β1‑induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5 Corrigendum in /10.3892/ol.2018.8427

Ariundavaa Boldbaatar, Sunyi Lee, Sora Han, Ae Lee Jeong, Hye In Ka, Sumiyasuren Buyanravjikh, Jeong Hyung Lee, Jong‑Seok Lim, Myung Sok Lee, Young Yang
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Differential gene expression analysis in glioblastoma cells and normal human brain cells based on GEO database

Anping Wang, Guibin Zhang
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Impact of the individualization of the first‑line chemotherapy for advanced colorectal cancer based on collagen gel droplet‑embedded drug sensitivity test

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Akinori Nakatani, Kiichi Nagayasu, Shigetoshi Naito, Tsuyoshi Sato, Kenji Kishine, Yu Abe, Chihiro Hara, Susumu Yamada, Satomi Mashiko, Isao Nagaoka
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Temporomandibular dislocation caused by pancreatic cancer metastasis: A case report

Shinpei Matsuda, Hitoshi Yoshimura, Sadahiko Kondo, Kazuo Sano
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Effect of pretreatment psoas muscle mass on survival for patients with unresectable pancreatic cancer undergoing systemic chemotherapy

Noriko Ishii, Yoshinori Iwata, Hiroki Nishikawa, Hirayuki Enomoto, Nobuhiro Aizawa, Akio Ishii, Yuho Miyamoto, Yukihisa Yuri, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Ryo Takata, Hiroko Iijima, Shuhei Nishiguchi
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Article

Induction of oxidative stress by anticancer drugs in the presence and absence of cells

Chikako Yokoyama, Yuto Sueyoshi, Mika Ema, Yumi Mori, Kazuto Takaishi, Hisashi Hisatomi
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Gene expression profile comparison between colorectal cancer and adjacent normal tissues

Qian Yang, Maohui Feng, Xiang Ma, Huachi Li, Wei Xie
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Transcriptome analysis reveals dysregulated long non‑coding RNAs and mRNAs associated with extrahepatic cholangiocarcinoma progression

Fumin Zhang, Ming Wan, Yi Xu, Zhenglong Li, Pengcheng Kang, Xingming Jiang, Yimin Wang, Zhidong Wang, Xiangyu Zhong, Chunlong Li, Yunfu Cui
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Article

Comparison of miRNA and gene expression profiles between metastatic and primary prostate cancer

Kaimin Guo, Zuowen Liang, Fubiao Li, Hongliang Wang
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Structural MRI research in patients with nasopharyngeal carcinoma following radiotherapy: A DTI and VBM study

Xi Leng, Peng Fang, Huan Lin, Jie An, Xin Tan, Chi Zhang, Donglin Wu, Wen Shen, Shijun Qiu
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MicroRNA‑25 contributes to cisplatin resistance in gastric cancer cells by inhibiting forkhead box O3a

Jingbo He, Huixiong Qi, Fang Chen, Chuanhua Cao
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Overexpression of CD164 in oral cavity squamous cell carcinoma predicts a favourable prognosis

Jia‑Hong Chen, Wei‑Liang Chen, James Yi‑Hsin Chan, Yuan‑Wu Chen, Yi‑Jen Peng, Ming‑Fang Cheng, Chun‑Shu Lin
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Article

Epigenetic analysis of FHL1 tumor suppressor gene in human liver cancer

Jun Wang, Fang Huang, Jian Huang, Jindan Kong, Shenglan Liu, Jun Jin
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Case Report

Acute renal failure due to small cell neuroendocrine carcinoma of the left kidney: A case report

Hakan Bahadir Haberal, Şenol Tonyali, Dilek Ertoy Baydar, Cenk Yücel Bilen
Pages: 6117-6120
Published online on: 15 September 2017

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Article

NUDT expression is predictive of prognosis in patients with clear cell renal cell carcinoma

Yue Wang, Fangning Wan, Kun Chang, Xiaolin Lu, Bo Dai, Dingwei Ye
Pages: 6121-6128
Published online on: 18 September 2017

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Article

Potato freeze‑thaw solution enhances immune function and antitumor activity in vivo

Guihua Xu, Jie Shen, Peng Sun, Yan Niu, Pengwei Zhao, Pingping Tang, Jiayi Zhang, Chunxue Fei, Leinan Bu, Zhiyi Yue, Honghao Liu, Zhiqiang Wang, Limin Yang, Dejun Sun
Pages: 6129-6134
Published online on: 15 September 2017

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Article

Combination of calcineurin B subunit (CnB) and 5‑fluorouracil reverses 5‑fluorouracil‑induced immunosuppressive effect and enhances the antitumor activity in hepatocellular carcinoma

Wenlong Zhang, Youxiu Zhong, Hongfei Cui, Liya Wang, Rui Yang, Zhenyi Su, Benqiong Xiang, Qun Wei
Pages: 6135-6142
Published online on: 15 September 2017

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Article

Downregulated long non‑coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells

Zhiwei Zhao, Junlai Xue, Yan Song, Tianyou Liu, Daxun Piao
Pages: 6143-6150
Published online on: 15 September 2017

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Article

Expression of c‑Met and hepatocyte growth factor in various gastric pathologies and its association with Helicobacter pylori infection

Chuan Xie, Zhen Yang, Yi Hu, Ximei Cao, Jiang Chen, Yin Zhu, Nonghua Lu
Pages: 6151-6155
Published online on: 18 September 2017

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Article

Rs1008805 polymorphism of CYP19A1 gene is associated with the efficacy of hormone therapy in stage I‑II and operable stage III breast cancer

Xiying Shao, Lei Luo, Yong Guo, Xiaohong Xu, Dehou Deng, Jianguo Feng, Yuheng Ding, Hanzhou Mou, Ping Huang, Lei Shi, Yuan Huang, Weiwu Ye, Caijin Lou, Zhanhong Chen, Yabing Zheng, Xiaojia Wang
Pages: 6156-6162
Published online on: 18 September 2017

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Article

Preparation, pharmacokinetics, tissue distribution and antitumor effect of sorafenib‑incorporating nanoparticles in vivo

Xia Sheng, Tao Huang, Jianmin Qin, Qi Li, Weiwei Wang, Liandong Deng, Anjie Dong
Pages: 6163-6169
Published online on: 14 September 2017

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Article

Artesunate inhibits proliferation and invasion of mouse hemangioendothelioma cells in vitro and of tumor growth in vivo

Ning Wang, Hongxia Chen, Yinping Teng, Xionghui Ding, Huan Wu, Xianqing Jin
Pages: 6170-6176
Published online on: 18 September 2017

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Article

Cancer cell‑expressed B7‑H3 regulates the differentiation of tumor‑associated macrophages in human colorectal carcinoma

Yong Mao, Lujun Chen, Fengming Wang, Dawei Zhu, Xiaosong Ge, Dong Hua, Jing Sun
Pages: 6177-6183
Published online on: 14 September 2017

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Article

CDX2 is involved in microRNA‑associated inflammatory carcinogenesis in gastric cancer

Motonobu Saito, Hirokazu Okayama, Katsuharu Saito, Jin Ando, Kensuke Kumamoto, Izumi Nakamura, Shinji Ohki, Yoshimasa Ishi, Seiichi Takenoshita
Pages: 6184-6190
Published online on: 15 September 2017

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Article

Overexpression of HS6ST2 is associated with poor prognosis in patients with gastric cancer

Yi Jin, Jun He, Jing Du, Ru‑Xuan Zhang, Hai‑Bo Yao, Qin‑Shu Shao
Pages: 6191-6197
Published online on: 14 September 2017

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Article

Overexpression of Rictor protein in colorectal cancer is correlated with tumor progression and prognosis

Lifeng Wang, Jia Qi, Jinlong Yu, Haijin Chen, Zhaowei Zou, Xiaohua Lin, Linlang Guo
Pages: 6198-6202
Published online on: 14 September 2017

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Article

JAB1‑STAT3 activation loop is associated with recurrence following 5‑fluorouracil‑based adjuvant chemotherapy in human colorectal cancer

Naruji Kugimiya, Arata Nishimoto, Tohru Hosoyama, Koji Ueno, Yoshihiro Takemoto, Eijiro Harada, Tadahiko Enoki , Kimikazu Hamano
Pages: 6203-6209
Published online on: 18 September 2017

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Article

The expression and significance of histone lysine methylation in endometrial cancer

Qing Li, Nan Jia, Xiang Tao, Keqin Hua, Weiwei Feng
Pages: 6210-6216
Published online on: 15 September 2017

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Article

Cleistanthin A inhibits the invasion and metastasis of human melanoma cells by inhibiting the expression of matrix metallopeptidase‑2 and ‑9

Sheng Pan, Hengji Cai, Lixiong Gu, Shuanglin Cao
Pages: 6217-6223
Published online on: 08 September 2017

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Article

Significance of imaging and clinical features in the differentiation between primary and secondary pulmonary lymphoma

Yuhao Dong, Miaoyu Zeng, Bin Zhang, Lujun Han, Entao Liu, Zhouyang Lian, Jing Liu, Changhong Liang, Shuixing Zhang
Pages: 6224-6230
Published online on: 15 September 2017

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Article

Overexpression of calcyphosine is associated with poor prognosis in esophageal squamous cell carcinoma

Feng Li, Dengyan Zhu, Yang Yang, Kai Wu, Song Zhao
Pages: 6231-6237
Published online on: 15 September 2017

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Case Report

Yolk sac tumor of upper lip: A case report

Zhanwei Chen, Peihui Zheng, Shengyun Huang, Dongsheng Zhang
Pages: 6238-6242
Published online on: 08 September 2017

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Article

Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Pages: 6243-6250
Published online on: 21 August 2017

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Article

E6/E7 proteins are potential markers for the screening and diagnosis of cervical pre‑cancerous lesions and cervical cancer in a Chinese population

Wen‑Jing Shi, Hao Liu, Dan Wu, Zhen‑Hua Tang, Yu‑Chen Shen, Lin Guo
Pages: 6251-6258
Published online on: 14 September 2017

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Article

Regulatory network involving miRNAs and genes in serous ovarian carcinoma

Haiyan Zhao, Hao Xu, Luchen Xue
Pages: 6259-6268
Published online on: 14 September 2017

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Article

Sequence variations of mitochondrial DNA D‑loop region in patients with acute myeloid leukemia

Juan Zhou, Haimei Gou, Yuanxin Ye, Yi Zhou, Xiaojun Lu, Binwu Ying
Pages: 6269-6276
Published online on: 18 September 2017

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Article

Serum Golgi protein 73 is a prognostic rather than diagnostic marker in hepatocellular carcinoma

Min Dong, Zhan‑Hong Chen, Xing Li, Xiao‑Yun Li, Jing‑Yun Wen, Qu Lin, Xiao‑Kun Ma, Li Wei, Jie Chen, Dan‑Yun Ruan, Ze‑Xiao Lin, Tian‑Tian Wang, Dong‑Hao Wu, Xiang‑Yuan Wu
Pages: 6277-6284
Published online on: 14 September 2017

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Article

HMGB1‑mediated autophagy confers resistance to gemcitabine in hormone‑independent prostate cancer cells

Yi‑Xiang Zhang, Ye‑Qing Yuan, Xue‑Qi Zhang, Dong‑Long Huang, Yu‑Ying Wei, Jiang‑Gen Yang
Pages: 6285-6290
Published online on: 15 September 2017

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Article

Association between CBR1 polymorphisms and NSCLC in the Chinese population

Yong Guo, Yingying Shen, Yongming Xia, Jianzhong Gu
Pages: 6291-6297
Published online on: 14 September 2017

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Article

Direct effects of phenformin on metabolism/bioenergetics and viability of SH‑SY5Y neuroblastoma cells

Fintan Geoghegan, Naomi Chadderton, G. Jane Farrar, Daniela M. Zisterer, Richard K. Porter
Pages: 6298-6306
Published online on: 14 September 2017

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Article

Common mechanism of pathogenesis in various types of metastatic osteosarcoma

Dongqi Wang, Zongrang Song, Zhan Wang
Pages: 6307-6313
Published online on: 15 September 2017

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Article

Epigallocatechin‑3‑gallate induces apoptosis in acute promyelocytic leukemia cells via a SHP‑1‑p38α MAPK‑Bax cascade

Liugen Gan, Liang Zhong, Zhiling Shan, Chunlan Xiao, Ting Xu, Hao Song, Liu Li, Rong Yang, Beizhong Liu
Pages: 6314-6320
Published online on: 18 September 2017

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Retraction Open Access

[Retracted] Proteasome inhibitors in glioblastoma (Review)

Wen-Juan Huang, Wei-Wei Chen, Xia Zhang
Pages: 6321-6321
Published online on: 08 September 2017

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Article Open Access

Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Article Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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Article Open Access

NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Article Open Access

Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Article Open Access

Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Review Open Access

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Article Open Access

Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Article Open Access

Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Article Open Access

Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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