Molecular pathological predictive diagnostics in a patient with non‑small cell lung cancer treated with crizotinib therapy: A case report

  • Authors:
    • Libor Stanek
    • Drahomira Springer
    • Bohuslav Konopasek
    • Michal Vocka
    • Petra Tesarova
    • Martin Syrucek
    • Lubos Petruzelka
    • Ales Vicha
    • Zdenek Musil
  • View Affiliations

  • Published online on: October 11, 2017     https://doi.org/10.3892/ol.2017.7167
  • Pages:7545-7548
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Abstract

Lung cancer is one of the most common malignant cancers in the Czech Republic in men, with the highest mortality rate of all the malignant diseases. The development of biological treatment enables study into novel personalized treatment options. This type of treatment is usually of high quality, and is often demanding of predictive and biopsy diagnostics, which is dependent on the quality of the collected material and close cooperation among particular departments. The present study describes the complete biopsy and predictive examinations performed in a male patient with lung adenocarcinoma, with an emphasis on the logistics of the whole process and the application of the tyrosine kinase inhibitors, crizotinib and LDK378. The patient experienced a long overall survival time of 28 months from diagnosis.

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December 2017
Volume 14 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

2016 Impact Factor: 1.39
Ranked #68/217 Oncology
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APA
Stanek, L., Springer, D., Konopasek, B., Vocka, M., Tesarova, P., Syrucek, M. ... Musil, Z. (2017). Molecular pathological predictive diagnostics in a patient with non‑small cell lung cancer treated with crizotinib therapy: A case report. Oncology Letters, 14, 7545-7548. https://doi.org/10.3892/ol.2017.7167
MLA
Stanek, L., Springer, D., Konopasek, B., Vocka, M., Tesarova, P., Syrucek, M., Petruzelka, L., Vicha, A., Musil, Z."Molecular pathological predictive diagnostics in a patient with non‑small cell lung cancer treated with crizotinib therapy: A case report". Oncology Letters 14.6 (2017): 7545-7548.
Chicago
Stanek, L., Springer, D., Konopasek, B., Vocka, M., Tesarova, P., Syrucek, M., Petruzelka, L., Vicha, A., Musil, Z."Molecular pathological predictive diagnostics in a patient with non‑small cell lung cancer treated with crizotinib therapy: A case report". Oncology Letters 14, no. 6 (2017): 7545-7548. https://doi.org/10.3892/ol.2017.7167