CT and MR imaging features in phosphaturic mesenchymal tumor-mixed connective tissue: A case report
- Zhenshan Shi
- Yiqiong Deng
- Xiumei Li
- Yueming Li
- Dairong Cao
- Vikash Sahadeo Coossa
Published online on: February 5, 2018
Copyright: © Shi et al.
This is an open access article distributed under the terms of Creative Commons Attribution License.
Phosphaturic mesenchymal tumor‑mixed connective tissue (PMT‑MCT) is rare and usually benign and slow‑growing. The majority of these tumors is associated with sporadic tumor‑induced osteomalacia (TIO) or rickets, affect middle‑aged individuals and are located in the extremities. Previous imaging studies often focused on seeking the causative tumors of TIO, not on the radiological features of these tumors, especially magnetic resonance imaging (MRI) features. PMT‑MCT remains a largely misdiagnosed, ignored or unknown entity by most radiologists and clinicians. In the present case report, a review of the known literature of PMT‑MCT was conducted and the CT and MRI findings from three patient cases were described for diagnosing the small subcutaneous tumor. Typical MRI appearances of PMT‑MCT were isointense relative to the muscles on T1‑weighted imaging, and markedly hyperintense on T2‑weighted imaging containing variably flow voids, with markedly heterogeneous/homogenous enhancement on post contrast T1‑weighted fat-suppression imaging. Short time inversion recovery was demonstrated to be the optimal sequence in localizing the tumor.