1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
2
|
Sohda M and Kuwano H: Current status and
future prospects for esophageal cancer treatment. Ann Thorac
Cardiovasc Surg. 23:1–11. 2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Belkhiri A and El-Rifai W: Advances in
targeted therapies and new promising targets in esophageal cancer.
Oncotarget. 6:1348–1358. 2015. View Article : Google Scholar : PubMed/NCBI
|
4
|
Darnell JE Jr: Transcription factors as
targets for cancer therapy. Nat Rev Cancer. 2:740–749. 2002.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Seo HS, Liu DD, Bekele BN, Kim MK, Pisters
K, Lippman SM, Wistuba II and Koo JS: Cyclic AMP response
element-binding protein overexpression: A feature associated with
negative prognosis in never smokers with non-small cell lung
cancer. Cancer Res. 68:6065–6073. 2008. View Article : Google Scholar : PubMed/NCBI
|
6
|
Shankar DB, Cheng JC, Kinjo K, Federman N,
Moore TB, Gill A, Rao NP, Landaw EM and Sakamoto KM: The role of
CREB as a proto-oncogene in hematopoiesis and in acute myeloid
leukemia. Cancer Cell. 7:351–362. 2005. View Article : Google Scholar : PubMed/NCBI
|
7
|
van der Sligte NE, Kampen KR, ter Elst A,
Scherpen FJ, Meeuwsen-de Boer TG, Guryev V, van Leeuwen FN,
Kornblau SM and de Bont ES: Essential role for cyclic-AMP
responsive element binding protein 1 (CREB) in the survival of
acute lymphoblastic leukemia. Oncotarget. 6:14970–14981. 2015.
View Article : Google Scholar : PubMed/NCBI
|
8
|
Shabestari RM, Safa M, Alikarami F, Banan
M and Kazemi A: CREB knockdown inhibits growth and induces
apoptosis in human pre-B acute lymphoblastic leukemia cells through
inhibition of prosurvival signals. Biomed Pharmacother. 87:274–279.
2017. View Article : Google Scholar : PubMed/NCBI
|
9
|
Aggarwal S, Kim SW, Ryu SH, Chung WC and
Koo JS: Growth suppression of lung cancer cells by targeting cyclic
AMP response element-binding protein. Cancer Res. 68:981–988. 2008.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Linnerth NM, Greenaway JB, Petrik JJ and
Moorehead RA: cAMP response element-binding protein is expressed at
high levels in human ovarian adenocarcinoma and regulates ovarian
tumor cell proliferation. Int J Gynecol Cancer. 18:1248–1257. 2008.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Tan X, Wang S, Yang B, Zhu L, Yin B, Chao
T, Zhao J, Yuan J, Qiang B and Peng X: The CREB-miR-9 negative
feedback minicircuitry coordinates the migration and proliferation
of glioma cells. PLoS One. 7:e495702012. View Article : Google Scholar : PubMed/NCBI
|
12
|
Son J, Lee JH, Kim HN, Ha H and Lee ZH:
cAMP-response-element-binding protein positively regulates breast
cancer metastasis and subsequent bone destruction. Biochem Biophys
Res Commun. 398:309–314. 2010. View Article : Google Scholar : PubMed/NCBI
|
13
|
Shukla A, Bosenberg MW, MacPherson MB,
Butnor KJ, Heintz NH, Pass HI, Carbone M, Testa JR and Mossman BT:
Activated cAMP response element binding protein is overexpressed in
human mesotheliomas and inhibits apoptosis. Am J Pathol.
175:2197–2206. 2009. View Article : Google Scholar : PubMed/NCBI
|
14
|
Jean D and Bar-Eli M: Regulation of tumor
growth and metastasis of human melanoma by the CREB transcription
factor family. Mol Cell Biochem. 212:19–28. 2000. View Article : Google Scholar : PubMed/NCBI
|
15
|
Liu YL, Lensing SY, Yan Y, Cooper TM, Loh
ML and Emanuel PD: Deficiency of CREB and over expression of
miR-183 in juvenile myelomonocytic leukemia. Leukemia.
27:1585–1588. 2013. View Article : Google Scholar : PubMed/NCBI
|
16
|
Huang GL, Liao D, Chen H, Lu Y, Chen L, Li
H, Li B, Liu W, Ye C, Li T, et al: The protein level and
transcription activity of activating transcription factor 1 is
regulated by prolyl isomerase Pin1 in nasopharyngeal carcinoma
progression. Cell Death Dis. 7:e25712016. View Article : Google Scholar : PubMed/NCBI
|
17
|
Li L, Wang M, Yu G, Chen P, Li H, Wei D,
Zhu J, Xie L, Jia H, Shi J, et al: Overactivated neddylation
pathway as a therapeutic target in lung cancer. J Natl Cancer Inst.
106:dju0832014. View Article : Google Scholar : PubMed/NCBI
|
18
|
Chen P, Hu T, Liang Y, Li P, Chen X, Zhang
J, Ma Y, Hao Q, Wang J, Zhang P, et al: Neddylation inhibition
activates the extrinsic apoptosis pathway through ATF4-CHOP-DR5
axis in human esophageal cancer cells. Clin Cancer Res.
22:4145–4157. 2016. View Article : Google Scholar : PubMed/NCBI
|
19
|
Hu T, Qi H, Li P, Zhao G, Ma Y, Hao Q, Gao
C, Zhang Y, Wang C, Yang M, et al: Comparison of GFP-expressing
imageable mouse models of human esophageal squamous cell carcinoma
established in various anatomical sites. Anticancer Res.
35:4655–4663. 2015.PubMed/NCBI
|
20
|
Hu T, Fu Q, Chen P, Zhang K and Guo D:
Generation of a stable mammalian cell line for simultaneous
expression of multiple genes by using 2A peptide-based lentiviral
vector. Biotechnol Lett. 31:353–359. 2009. View Article : Google Scholar : PubMed/NCBI
|
21
|
Huang FL and Yu SJ: Esophageal cancer:
Risk factors, genetic association, and treatment. Asian J Surg.
S1015–S9584. 2016.
|
22
|
Sakamoto KM and Frank DA: CREB in the
pathophysiology of cancer: Implications for targeting transcription
factors for cancer therapy. Clin Cancer Res. 15:2583–2587. 2009.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Steven A and Seliger B: Control of CREB
expression in tumors: From molecular mechanisms and signal
transduction pathways to therapeutic target. Oncotarget.
7:35454–35465. 2016. View Article : Google Scholar : PubMed/NCBI
|
24
|
Rozenberg J, Rishi V, Orosz A, Moitra J,
Glick A and Vinson C: Inhibition of CREB function in mouse
epidermis reduces papilloma formation. Mol Cancer Res. 7:654–664.
2009. View Article : Google Scholar : PubMed/NCBI
|
25
|
Liu W, Wu Y, Wang L, Gao L, Wang Y, Liu X,
Zhang K, Song J, Wang H, Bayer TA, et al: Protein signature for
non-small cell lung cancer prognosis. Am J Cancer Res. 4:256–269.
2014.PubMed/NCBI
|
26
|
Pigazzi M, Ricotti E, Germano G, Faggian
D, Aricò M and Basso G: cAMP response element binding protein
(CREB) overexpression CREB has been described as critical for
leukemia progression. Haematologica. 92:1435–1437. 2007. View Article : Google Scholar : PubMed/NCBI
|
27
|
Jean D, Harbison M, McConkey DJ, Ronai Z
and Bar-Eli M: CREB and its associated proteins act as survival
factors for human melanoma cells. J Biol Chem. 273:24884–24890.
1998. View Article : Google Scholar : PubMed/NCBI
|
28
|
Abramovitch R, Tavor E, Jacob-Hirsch J,
Zeira E, Amariglio N, Pappo O, Rechavi G, Galun E and Honigman A: A
pivotal role of cyclic AMP-responsive element binding protein in
tumor progression. Cancer Res. 64:1338–1346. 2004. View Article : Google Scholar : PubMed/NCBI
|
29
|
Leslie MC and Bar-Eli M: Regulation of
gene expression in melanoma: New approaches for treatment. J Cell
Biochem. 94:25–38. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Xie F, Li BX, Kassenbrock A, Xue C, Wang
X, Qian DZ, Sears RC and Xiao X: Identification of a potent
inhibitor of CREB-mediated gene transcription with efficacious in
vivo anticancer activity. J Med Chem. 58:5075–5087. 2015.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Xie F, Li BX, Broussard C and Xiao X:
Identification, synthesis and evaluation of substituted
benzofurazans as inhibitors of CREB-mediated gene transcription.
Bioorg Med Chem Lett. 23:5371–5375. 2013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Mitton B, Hsu K, Dutta R, Tiu BC, Cox N,
McLure KG, Chae HD, Smith M, Eklund EA, Solow-Cordero DE and
Sakamoto KM: Small molecule screen for inhibitors of expression
from canonical CREB response element-containing promoters.
Oncotarget. 7:8653–8662. 2016. View Article : Google Scholar : PubMed/NCBI
|
33
|
Li BX, Yamanaka K and Xiao X:
Structure-activity relationship studies of naphthol AS-E and its
derivatives as anticancer agents by inhibiting CREB-mediated gene
transcription. Bioorg Med Chem. 20:6811–6820. 2012. View Article : Google Scholar : PubMed/NCBI
|
34
|
Li BX, Gardner R, Xue C, Qian DZ, Xie F,
Thomas G, Kazmierczak SC, Habecker BA and Xiao X: Systemic
inhibition of CREB is well-tolerated in vivo. Sci Rep. 6:345132016.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Pan J, Li X, Wu W, Xue M, Hou H, Zhai W
and Chen W: Long non-coding RNA UCA1 promotes cisplatin/gemcitabine
resistance through CREB modulating miR-196a-5p in bladder cancer
cells. Cancer Lett. 382:64–76. 2016. View Article : Google Scholar : PubMed/NCBI
|
36
|
Zhang Y, Yu J, Liu H, Ma W, Yan L, Wang J
and Li G: Novel epigenetic CREB-miR-630 signaling axis regulates
radiosensitivity in colorectal cancer. PLoS One. 10:e01338702015.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Suarez CD, Deng X and Hu CD: Targeting
CREB inhibits radiation-induced neuroendocrine differentiation and
increases radiation-induced cell death in prostate cancer cells. Am
J Cancer Res. 4:850–861. 2014.PubMed/NCBI
|
38
|
Pigazzi M, Manara E, Baron E and Basso G:
miR-34b targets cyclic AMP-responsive element binding protein in
acute myeloid leukemia. Cancer Res. 69:2471–2478. 2009. View Article : Google Scholar : PubMed/NCBI
|
39
|
De Falco V, Tamburrino A, Ventre S,
Castellone MD, Malek M, Manié SN and Santoro M: CD44 proteolysis
increases CREB phosphorylation and sustains proliferation of
thyroid cancer cells. Cancer Res. 72:1449–1458. 2012. View Article : Google Scholar : PubMed/NCBI
|
40
|
Desdouets C, Matesic G, Molina CA, Foulkes
NS, Sassone-Corsi P, Brechot C and Sobczak-Thepot J: Cell cycle
regulation of cyclin A gene expression by the cyclic AMP-responsive
transcription factors CREB and CREM. Mol Cell Biol. 15:3301–3309.
1995. View Article : Google Scholar : PubMed/NCBI
|
41
|
Yoshizumi M, Wang H, Hsieh CM, Sibinga NE,
Perrella MA and Lee ME: Down-regulation of the cyclin A promoter by
transforming growth factor-beta1 is associated with a reduction in
phosphorylated activating transcription factor-1 and cyclic
AMP-responsive element-binding protein. J Biol Chem.
272:22259–22264. 1997. View Article : Google Scholar : PubMed/NCBI
|
42
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
43
|
Dobroff AS, Wang H, Melnikova VO, Villares
GJ, Zigler M, Huang L and Bar-Eli M: Silencing cAMP-response
element-binding protein (CREB) identifies CYR61 as a tumor
suppressor gene in melanoma. J Biol Chem. 284:26194–26206. 2009.
View Article : Google Scholar : PubMed/NCBI
|
44
|
Wang X, Ren Y, Zhuang H, Meng X, Huang S,
Li Y, Hehir M and Wang P: Decrease of phosphorylated proto-oncogene
CREB at Ser 133 site inhibits growth and metastatic activity of
renal cell cancer. Expert Opin Ther Targets. 19:985–995. 2015.
View Article : Google Scholar : PubMed/NCBI
|
45
|
Wu D, Zhau HE, Huang WC, Iqbal S, Habib
FK, Sartor O, Cvitanovic L, Marshall FF, Xu Z and Chung LW:
cAMP-responsive element-binding protein regulates vascular
endothelial growth factor expression: Implication in human prostate
cancer bone metastasis. Oncogene. 26:5070–5077. 2007. View Article : Google Scholar : PubMed/NCBI
|
46
|
Melnikova VO, Dobroff AS, Zigler M,
Villares GJ, Braeuer RR, Wang H, Huang L and Bar-Eli M: CREB
inhibits AP-2alpha expression to regulate the malignant phenotype
of melanoma. PLoS One. 5:e124522010. View Article : Google Scholar : PubMed/NCBI
|