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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2018 Volume 39 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

A double-edged function of DDX3, as an oncogene or tumor suppressor, in cancer progression (Review)

Yu He, Dan Zhang, Yanfang Yang, Xixi Wang, Xinyu Zhao, Peng Zhang, Hongxia Zhu, Ningzhi Xu, Shufang Liang
Pages: 883-892
Published online on: 09 January 2018

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Review

Application of multifunctional nanomaterials in cancer vaccines (Review)

Biao Fu, Xiaomei Huang, Jiaqi Deng, Daijiao Gu, Qibing Mei, Mingming Deng, Shixiao Tang, Muhan Lü
Pages: 893-900
Published online on: 10 January 2018

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Review

Mechanisms of the CDK4/6 inhibitor palbociclib (PD 0332991) and its future application in cancer treatment (Review)

Minghui Liu, Hongyu Liu, Jun Chen
Pages: 901-911
Published online on: 19 January 2018

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Article Open Access

Inactivation of DNA-PK by knockdown DNA-PKcs or NU7441 impairs non-homologous end-joining of radiation-induced double strand break repair

Jun Dong, Yufeng Ren, Tian Zhang, Zhenyu Wang, Clifton C. Ling, Gloria C. Li, Fuqiu He, Chengtao Wang, Bixiu Wen
Pages: 912-920
Published online on: 16 January 2018

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Article Open Access

Effects of diphyllin as a novel V-ATPase inhibitor on TE-1 and ECA-109 cells

Haijiao Chen, Pengfei Liu, Ting Zhang, Yi Gao, Yingdi Zhang, Xiuyun Shen, Xiao Li, Weidong Shen
Pages: 921-928
Published online on: 04 January 2018

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Article Open Access

Meta-analysis of mRNA expression profiles to identify differentially expressed genes in lung adenocarcinoma tissue from smokers and non-smokers

Xiaona He, Cheng Zhang, Chao Shi, Quqin Lu
Pages: 929-938
Published online on: 08 January 2018

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Article Open Access

Knockdown of hnRNP A2/B1 inhibits cell proliferation, invasion and cell cycle triggering apoptosis in cervical cancer via PI3K/AKT signaling pathway

Xiang Shi, Li Ran, Yao Liu, Shu‑Huai Zhong, Ping‑Ping Zhou, Ming‑Xin Liao, Wen Fang
Pages: 939-950
Published online on: 05 January 2018

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Article Open Access

CircDOCK1 suppresses cell apoptosis via inhibition of miR‑196a‑5p by targeting BIRC3 in OSCC

Liping Wang, Yongxiang Wei, Yongyong Yan, Haiyan Wang, Jiantin Yang, Zhichao Zheng, Jun Zha, Peng Bo, Yinghua Tang, Xueqi Guo, Weihong Chen, Xinxin Zhu, Linhu Ge
Pages: 951-966
Published online on: 28 December 2017

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Article Open Access

Chronic oxymatrine treatment induces resistance and epithelial‑mesenchymal transition through targeting the long non-coding RNA MALAT1 in colorectal cancer cells Retraction in /10.3892/or.2024.8732

Yibai Xiong, Jun Wang, Huirong Zhu, Lingshuang Liu, Yi Jiang
Pages: 967-976
Published online on: 10 January 2018

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Article Open Access

hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1 Retraction in /10.3892/or.2024.8818

Xin He, Saijun Fan
Pages: 977-984
Published online on: 15 December 2017

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Article Open Access

Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca2+ signaling in SKOV3 cells

Lu Xu, Qi Xie, Ling Qi, Chunyan Wang, Na Xu, Weimin Liu, Yang Yu, Songyan Li, Ye Xu
Pages: 985-992
Published online on: 19 December 2017

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Article Open Access

DNA methylation enzyme inhibitor RG108 suppresses the radioresistance of esophageal cancer

Yao Ou, Quan Zhang, Yiting Tang, Zhonghua Lu, Xujing Lu, Xifa Zhou, Changmin Liu
Pages: 993-1002
Published online on: 11 January 2018

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Article Open Access

Bioinformatic identification of chemoresistance-associated microRNAs in breast cancer based on microarray data

Ya-Wen Wang, Weiguo Zhang, Rong Ma
Pages: 1003-1010
Published online on: 10 January 2018

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Article Open Access

Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma

Da-Peng Yun, Yu-Qi Wang, De-Long Meng, Yuan-Yuan Ji, Ju-Xiang Chen, Hong-Yan Chen, Da-Ru Lu
Pages: 1011-1022
Published online on: 22 January 2018

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Article Open Access

NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition

Yi Zhang, Wei Wang, Yifei Wang, Xiaohui Huang, Zhaohui Zhang, Bin Chen, Wenxuan Xie, Shaoqiang Li, Shunli Shen, Baogang Peng
Pages: 1023-1033
Published online on: 22 January 2018

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Article Open Access

Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway Corrigendum in /10.3892/or.2025.8910

Ning Zhang, Junjun Qiu, Tingting Zheng, Xiaodan Zhang, Keqin Hua, Ying Zhang
Pages: 1034-1042
Published online on: 15 December 2017

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Article Open Access

Characterization of different osteoclast phenotypes in the progression of bone invasion by oral squamous cell carcinoma

Jingjing Quan, Yuluan Hou, Weiling Long, Shu Ye, Zhiyuan Wang
Pages: 1043-1051
Published online on: 19 December 2017

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Article Open Access

Paeoniflorin exerts antitumor effects by inactivating S phase kinase-associated protein 2 in glioma cells

Jia Ouyang, Hui Xu, Ming Li, Xingliang Dai, Fengqing Fu, Xueguang Zhang, Qing Lan
Pages: 1052-1062
Published online on: 28 December 2017

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Article Open Access

Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells Expression of Concern in /10.3892/or.2026.9146

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Pages: 1063-1071
Published online on: 29 December 2017

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Article Open Access

HIF‑1α‑induced upregulation of lncRNA UCA1 promotes cell growth in osteosarcoma by inactivating the PTEN/AKT signaling pathway

Tengfei Li, Yang Xiao, Tunsheng Huang
Pages: 1072-1080
Published online on: 03 January 2018

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Article Open Access

Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway

Liwen Chen, Ding'an Zhou, Zhehao Liu, Xinhao Huang, Qianfan Liu, Yiping Kang, Zili Chen, Yuntao Guo, Haitao Zhu, Chengyi Sun
Pages: 1081-1089
Published online on: 08 January 2018

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Article Open Access

miR‑873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1

Hui Gong, Lishan Fang, Yifan Li, Jihui Du, Bei Zhou, Xiu Wang, Hekai Zhou, Lingli Gao, Kaixin Wang, Juan Zhang
Pages: 1090-1098
Published online on: 08 January 2018

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Article Open Access

Detection of high-grade neoplasia in air-dried cervical PAP smears by a microRNA-based classifier

Mikhail K. Ivanov, Sergei E. Titov, Sergei A. Glushkov, Victoria V. Dzyubenko, Anastasia V. Malek, Polina A. Arkhangelskaya, Roman B. Samsonov, Andrey A. Mikhetko, Elena V. Bakhidze, Igor V. Berlev, Nikolay N. Kolesnikov
Pages: 1099-1111
Published online on: 12 January 2018

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Article Open Access

Fra‑1 enhances the radioresistance of colon cancer cells to X‑ray or C‑ion radiation

Satoshi Endo, Mayumi Fujita, Shigeru Yamada, Kaori Imadome, Fumiaki Nakayama, Tetsuro Isozaki, Takeshi Yasuda, Takashi Imai, Hisahiro Matsubara
Pages: 1112-1118
Published online on: 19 January 2018

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Article

Heat shock protein 27 knockdown using nucleotide‑based therapies enhances sensitivity to 5-FU chemotherapy in SW480 human colon cancer cells

Takehiro Shimada, Masashi Tsuruta, Hirotoshi Hasegawa, Koji Okabayashi, Kohei Shigeta, Takashi Ishida, Yusuke Asada, Hirofumi Suzumura, Kaoru Koishikawa, Shingo Akimoto, Yuko Kitagawa
Pages: 1119-1124
Published online on: 03 January 2018

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Article

Immune response-associated gene profiling in Japanese melanoma patients using multi-omics analysis

Yasuto Akiyama, Yoshio Kiyohara, Shusuke Yoshikawa, Masaki Otsuka, Ryota Kondou, Chizu Nonomura, Haruo Miyata, Akira Iizuka, Tadashi Ashizawa, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Takashi Sugino, Ken Yamaguchi
Pages: 1125-1131
Published online on: 21 December 2017

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Article

Long non-coding RNA MEG3 functions as a tumour suppressor and has prognostic predictive value in human pancreatic cancer

Ling Ma, Feng Wang, Chong Du, Zhengkui Zhang, Huahu Guo, Xuehai Xie, Hongqiao Gao, Yan Zhuang, Marko Kornmann, Hong Gao, Xiaodong Tian, Yinmo Yang
Pages: 1132-1140
Published online on: 02 January 2018

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Article

Rhus verniciflua Stokes extract induces inhibition of cell growth and apoptosis in human chronic myelogenous leukemia K562 cells

Kyung-Wook Lee, Eun-Sik Um, Bo-Bae Jung, Eun-Sol Choi, Eun-Young Kim, Seungbo Lee, Eungyeong Jang, Jang-Hoon Lee, Youngchul Kim
Pages: 1141-1147
Published online on: 03 January 2018

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Article

Inhibition of Gli leads to antitumor growth and enhancement of cisplatin-induced cytotoxicity in large cell neuroendocrine carcinoma of the lung

Tsukasa Ishiwata, Shunichiro Iwasawa, Takahiro Ebata, Mengmeng Fan, Yuji Tada, Koichiro Tatsumi, Yuichi Takiguchi
Pages: 1148-1154
Published online on: 03 January 2018

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Article

Overexpression of interleukin-32α promotes invasion by modulating VEGF in hepatocellular carcinoma

Wen-Bo Zhao, Quan-Li Wang, Yan-Tian Xu, Shi-Feng Xu, Yang Qiu, Feng Zhu
Pages: 1155-1162
Published online on: 19 December 2017

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Article

α-solanine enhances the chemosensitivity of esophageal cancer cells by inducing microRNA‑138 expression

Jianbo Wu, Li Wang, Xinhui Du, Qianqian Sun, Yuanyuan Wang, Min Li, Wenqiao Zang, Kangdong Liu, Guoqiang Zhao
Pages: 1163-1172
Published online on: 04 January 2018

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Article

Function of miR‑152 as tumor suppressor in oral squamous cell carcinoma cells by targeting c‑MET Retraction in /10.3892/or.2022.8254

Minghe Li, Zhihong Li, Xue Wang, Yumei Wang, Cong Zhao, Lei Wang
Pages: 1173-1180
Published online on: 15 December 2017

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Article

Licochalcone A suppresses hexokinase 2-mediated tumor glycolysis in gastric cancer via downregulation of the Akt signaling pathway

Jian Wu, Xingxing Zhang, Yaohui Wang, Qingmin Sun, Min Chen, Shenlin Liu, Xi Zou
Pages: 1181-1190
Published online on: 14 December 2017

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Article

Inhibition effect of triptolide on human epithelial ovarian cancer via adjusting cellular immunity and angiogenesis

Hui Hu, Genhua Huang, Haibin Wang, Xiaoli Li, Xiaobing Wang, Ying Feng, Buzhen Tan, Tingtao Chen
Pages: 1191-1196
Published online on: 15 December 2017

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Article

Construction and investigation of lncRNA-associated ceRNA regulatory network in papillary thyroid cancer

Yangjing Zhao, Hui Wang, Chengjiang Wu, Meina Yan, Haojie Wu, Jingzhe Wang, Xinxin Yang, Qixiang Shao
Pages: 1197-1206
Published online on: 10 January 2018

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Article

MicroRNA-let-7a regulates cell autophagy by targeting Rictor in gastric cancer cell lines MGC-803 and SGC-7901

Hao Fan, Mingkun Jiang, Bowen Li, Yu He, Chi Huang, Dakui Luo, Hao Xu, Li Yang, Jundong Zhou
Pages: 1207-1214
Published online on: 05 January 2018

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Article

Synthesis and application of 131I-fulvestrant as a targeted radiation drug for endocrine therapy in human breast cancer

Guobing Yin, Bin Zeng, Zhiping Peng, Ying Liu, Lu Sun, Changan Liu
Pages: 1215-1226
Published online on: 11 January 2018

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Article

Over-regulation of microRNA-133b inhibits cell proliferation of cisplatin-induced non-small cell lung cancer cells through PI3K/Akt and JAK2/STAT3 signaling pathway by targeting EGFR

Bin Li, Cui-Min Ding, Yan-Xiao Li, Jing-Cui Peng, Nan Geng, Wen-Wen Qin
Pages: 1227-1234
Published online on: 15 January 2018

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Article

MicroRNA‑16/VEGFR2/p38/NF‑κB signaling pathway regulates cell growth of human pituitary neoplasms

Bin Lu, Ge-Ling Liu, Fang Yu, Wei-Juan Li, Xiu-Xiu Xiang, Hong-Zhen Xiao
Pages: 1235-1244
Published online on: 22 January 2018

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Article

Targeting bladder cancer using activated T cells armed with bispecific antibodies

Juan Ma, Jing Ge, Xin Xue, Weigang Xiu, Pan Ma, Ximing Sun, Man Zhang
Pages: 1245-1252
Published online on: 11 January 2018

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Article

A 60 kDa prolactin variant secreted by cervical cancer cells modulates apoptosis and cytokine production

Adrián Ramírez De Arellano, Annie Riera Leal, Edgar I. Lopez-Pulido, Luis Renee González-Lucano, José Macías Barragan, Susana Del Toro Arreola, Mariel García-Chagollan, Claudia A. Palafox-Sánchez, José F. Muñoz-Valle, Ana Laura Pereira-Suárez
Pages: 1253-1260
Published online on: 19 January 2018

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Article

The role of aldehyde dehydrogenase 1A1 in B-cell non-Hodgkin's lymphoma

Ying-Hui Song, Mei-Zuo Zhong, Qin Chai, Kui-Yu Gong, Xiao-Lang Tan, Jin-Yue Hu, Gui-Hua Wang
Pages: 1261-1268
Published online on: 18 January 2018

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Article

Knockdown of immature colon carcinoma transcript 1 induces suppression of proliferation, S-phase arrest and apoptosis in leukemia cells

Guang-Yao Li, Ji-Zhu Liu, Li Zhang, Guo-Zhen Liu, Shuang-Jing Li, Tai-Wu Xiao, Jing-Xia Wang, Le-Xin Wang, Ming Hou
Pages: 1269-1275
Published online on: 03 January 2018

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Article

Mitochondrial pyruvate carrier modulates the epithelial-mesenchymal transition in cholangiocarcinoma

Tomofumi Ohashi, Hidetoshi Eguchi, Koichi Kawamoto, Masamitsu Konno, Ayumu Asai, Hugh Colvin, Yuji Ueda, Hirofumi Takaoka, Yoshifumi Iwagami, Daisaku Yamada, Tadafumi Asaoka, Takehiro Noda, Hiroshi Wada, Kunihito Gotoh, Shogo Kobayashi, Jun Koseki, Taroh Satoh, Kazuhiko Ogawa, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 1276-1282
Published online on: 20 December 2017

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Article

GC7 enhances cisplatin sensitivity via STAT3 signaling pathway inhibition and eIF5A2 inactivation in mesenchymal phenotype oral cancer cells

Liang Fang, Li Gao, Lei Xie, Guizhou Xiao
Pages: 1283-1291
Published online on: 15 December 2017

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Article

Additive antitumour effect of D‑allose in combination with cisplatin in non-small cell lung cancer cells

Nobuhiro Kanaji, Kazuyo Kamitori, Akram Hossain, Chisato Noguchi, Ayako Katagi, Norimitsu Kadowaki, Masaaki Tokuda
Pages: 1292-1298
Published online on: 04 January 2018

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Article

Peiminine serves as an adriamycin chemosensitizer in gastric cancer by modulating the EGFR/FAK pathway

Qianqian Tang, Yunfei Wang, Lanjing Ma, Meiling Ding, Tingyu Li, Yongzhan Nie, Zhengyi Gu
Pages: 1299-1305
Published online on: 03 January 2018

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Article

Effects of epidermal growth factor receptor fusion protein on the cytotoxic activity of SOCS1-silenced dendritic cells in vitro

Qichuan Jiang, Xuefeng Wang, Ming Qian, Dong Chen, Yanan Xu
Pages: 1306-1312
Published online on: 15 December 2017

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Article

Estrogen receptor β1 activation accelerates resistance to epidermal growth factor receptor-tyrosine kinase inhibitors in non-small cell lung cancer

Shengling Fu, Changyu Liu, Quanfu Huang, Sheng Fan, Hexiao Tang, Xiangning Fu, Bo Ai, Yongde Liao, Qian Chu
Pages: 1313-1321
Published online on: 04 January 2018

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Article

CHK1 inhibition sensitizes pancreatic cancer cells to gemcitabine via promoting CDK-dependent DNA damage and ribonucleotide reductase downregulation

Min Liang, Tiangang Zhao, Linfeng Ma, Yingjie Guo
Pages: 1322-1330
Published online on: 20 December 2017

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Article

2-Phenyl-4-quinolone (YT-1) induces G2/M phase arrest and an intrinsic apoptotic mechanism in human leukemia cells

Meng‑Wei Lin, Jai‑Sing Yang, Chi‑Cheng Lu, Chingju Lin, Sheng‑Chu Kuo, Fuu‑Jen Tsai, Miau‑Rong Lee
Pages: 1331-1337
Published online on: 20 December 2017

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Article

Serum microRNA panel excavated by machine learning as a potential biomarker for the detection of gastric cancer

Yao Huang, Jie Zhu, Wenshuai Li, Ziqiang Zhang, Panpan Xiong, Hong Wang, Jun Zhang
Pages: 1338-1346
Published online on: 19 December 2017

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Article

Galectin-1 expression in activated pancreatic satellite cells promotes fibrosis in chronic pancreatitis/pancreatic cancer via the TGF-β1/Smad pathway

Dong Tang, Qi Wu, Jingqiu Zhang, Hongpeng Zhang, Zhongxu Yuan, Jiaming Xu, Yang Chong, Yuqin Huang, Qingquan Xiong, Sen Wang, Ying Tian, Yongdie Lu, Xiao Ge, Wenjing Shen, Daorong Wang
Pages: 1347-1355
Published online on: 09 January 2018

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Article

Epithelial mesenchymal transition induced by the CXCL9/CXCR3 axis through AKT activation promotes invasion and metastasis in tongue squamous cell carcinoma Corrigendum in /10.3892/or.2020.7883

Ziliang Li, Jianqi Liu, Lei Li, Shuai Shao, Jianhua Wu, Li Bian, Yongwen He
Pages: 1356-1368
Published online on: 20 December 2017

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Article

Targeting the overexpressed CREB inhibits esophageal squamous cell carcinoma cell growth

Ping Chen, Miaomiao Li, Qianyun Hao, Xuesong Zhao, Tao Hu
Pages: 1369-1377
Published online on: 19 December 2017

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Article

Terrein inhibits migration of human breast cancer cells via inhibition of the Rho and Rac signaling pathways

Anongnard Kasorn, Fabien Loison, Thaned Kangsamaksin, Suchada Jongrungruangchok, Mathurose Ponglikitmongkol
Pages: 1378-1386
Published online on: 04 January 2018

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Article

Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells

Xianliang Zeng, Sizeng Chen, Yanfeng Lin, Zhao Ke
Pages: 1387-1395
Published online on: 12 January 2018

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Article

Antibody-nanoparticle conjugate constructed with trastuzumab and nanoparticle albumin-bound paclitaxel for targeted therapy of human epidermal growth factor receptor 2-positive gastric cancer

Jian Xiong, Shuhua Han, Shuang Ding, Jingchao He, Haijun Zhang
Pages: 1396-1404
Published online on: 09 January 2018

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Article

Sigma-1 receptor (σ1R) is downregulated in hepatic malignant tumors and regulates HepG2 cell proliferation, migration and apoptosis

Qingxia Xu, Liang Li, Cuihong Han, Li Wei, Lingling Kong, Fanzhong Lin
Pages: 1405-1413
Published online on: 22 January 2018

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Article

Aspirin and metformin exhibit antitumor activity in murine breast cancer

Maoyuan Zhao, Yuyi Wang, Chi Du, Yanyang Liu, Nan Zhang, Feng Luo
Pages: 1414-1422
Published online on: 04 January 2018

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Article

TTF1‑NP induces protective autophagy during apoptosis by inhibiting the Akt/mTOR pathway and activating JNK in human liver cancer cells

Xuan Zhang, Meilan Zhang, Bin Xiao, Wenjun Jiao, Silin Zhang, Xuewu Zhang
Pages: 1423-1431
Published online on: 05 January 2018

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Article

Expression and prognostic significance of TRPV6 in the development and progression of pancreatic cancer Corrigendum in /10.3892/or.2022.8395

He Song, Ming Dong, Jianping Zhou, Weiwei Sheng, Xin Li, Wei Gao
Pages: 1432-1440
Published online on: 15 January 2018

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Article

CLDN5 affects lncRNAs acting as ceRNA dynamics contributing to regulating blood‑brain barrier permeability in tumor brain metastasis

Shun‑Chang Ma, Qi Li, Jia‑Yi Peng, Jian‑Long Zhouwen, Dai‑Nan Zhang, Chuan‑Bao Zhang, Wen‑Guo Jiang, Wang Jia
Pages: 1441-1453
Published online on: 10 January 2018

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Article

miR-141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1 Retraction in /10.3892/or.2023.8679

Song Xu, Jingping Ge, Zhengyu Zhang, Wenquan Zhou
Pages: 1454-1460
Published online on: 11 January 2018

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Article

miR-375 inhibits IFN-γ-induced programmed death 1 ligand 1 surface expression in head and neck squamous cell carcinoma cells by blocking JAK2/STAT1 signaling

Qingwei Wu, Yingying Zhao, Yiyuan Sun, Xiaojun Yan, Peihua Wang
Pages: 1461-1468
Published online on: 02 January 2018

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Article

Polysaccharide sulphated derivative from Aconitum coreanum induces cell apoptosis in the human brain glioblastoma U87MG cell line via the NF-κB/Bcl-2 cell apoptotic signaling pathway

Libo Sun, Zhijun Wang, Hailiang Wang, Jincheng Li, Huaxin Liang
Pages: 1469-1474
Published online on: 19 December 2017

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Article

Cytisine induces endoplasmic reticulum stress caused by calcium overload in HepG2 cells

Lei Yu, Bo Jiang, Zhifeng Chen, Xin Wang, Dongxue Shang, Xiaopo Zhang, Yongxue Sun, Jinghui Yang, Yubin Ji
Pages: 1475-1484
Published online on: 08 January 2018

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Article

Garcinone C exerts antitumor activity by modulating the expression of ATR/Stat3/4E‑BP1 in nasopharyngeal carcinoma cells

Yudui Xia, Xia Liu, Chunlin Zou, Shixiu Feng, Hongwei Guo, Yeguo Yang, Yong Lei, Jian Zhang, Yi Lu
Pages: 1485-1493
Published online on: 16 January 2018

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Article

MicroRNA-454 inhibits the malignant biological behaviours of gastric cancer cells by directly targeting mitogen-activated protein kinase 1 Retraction in /10.3892/or.2022.8276

Xiaodong Wang, Baichun Liu, Fuxing Wen, Ying Song
Pages: 1494-1504
Published online on: 20 December 2017

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Article

Serum and glucocorticoid-regulated kinase 1 (SGK1) is a predictor of poor prognosis in non-small cell lung cancer, and its dynamic pattern following treatment with SGK1 inhibitor and γ-ray irradiation was elucidated

Zhiyuan Tang, Qin Shen, Hao Xie, Zhu Zhou, Guanglin Shi, Caixin Zhang, Anaz Mohammed, Yi Wu, Songshi Ni, Xiaoyu Zhou
Pages: 1505-1515
Published online on: 03 January 2018

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Article

Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells

In-Hye Kim, Taek-Jeong Nam
Pages: 1516-1522
Published online on: 04 January 2018

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Article

Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway

Furong Liu, Song Gao, Yuxuan Yang, Xiaodan Zhao, Yameng Fan, Wenxia Ma, Danrong Yang, Aimin Yang, Yan Yu
Pages: 1523-1531
Published online on: 04 January 2018

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Article

MicroRNA-125 modulates radioresistance through targeting p21 in cervical cancer

Abraham Pedroza‑Torres, Alma D. Campos‑Parra, Oliver Millan‑Catalan, Yahir A. Loissell‑Baltazar, Horacio Zamudio‑Meza, David Cantú de León, Gonzalo Montalvo‑Esquivel, David Isla‑Ortiz, Luis A. Herrera, Óscar Ángeles‑Zaragoza, Guadalupe Robelo‑Romero, Ángel Herrera‑Gómez, Carlos Pérez‑Plasencia
Pages: 1532-1540
Published online on: 18 January 2018

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability

An Ni Lee, Chia Chang Wu, Su Wei Hu, Chih Heng Chen, Yi Te Chiang, Wei Tang Kao, Kai Yi Tzou, Chia Hung Liu, Shao Wei Dong, Yu Ting Wang, Yueh Lin Lee, Siou Bi Li, Che An Wu, Chiao Chun Liao, Ming Hsien Chan, Po Han Chiu, Chien Hsiu Li
Article Number: 198
Published online on: 30 September 2026

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Article Open Access

Loperamide enhances the radiosensitivity of cervical cancer cells via ferroptosis induction

Huarong Guo, Haixia Li, Shunkang Tian, Yunkai Zhang, Fuyun Wu, Jing Ke
Article Number: 197
Published online on: 30 September 2026

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Review Open Access

Mitochondrial mechanisms underlying spatial immune phenotypes in non‑small cell lung cancer: Implications for ICI response and cold‑to‑hot tumor conversion (Review)

Hongyi Lai, Ke Sun, Tong Mu, Xi Liu, Mingshan Liu
Article Number: 196
Published online on: 30 September 2026

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Article Open Access

PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway

Xu Li, Yuhui Ma
Article Number: 195
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑195‑5p is a potential diagnostic and therapeutic target for breast cancer

Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Article Number: 194
Published online on: 23 September 2026

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Article Open Access

SGPP1 as a tumor suppressor in esophageal squamous cell carcinoma: Potential molecular mechanisms involving UGT1A9/UGT2B28 and clinical prognostic significance

Linlin Su, Liubing Hou, Xuetao Han, Ge Zhang, Jiayuan Li, Yu Wang, Yuxin Han, Xiaoying Xue, Huandi Zhou
Article Number: 193
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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Journal Cover
December-2026 Volume 56 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang
Article Number: 199
Published online on: 30 September 2026

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