Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.

  • Authors:
    • R E Harris
    • S Kasbari
    • W B Farrar
  • View Affiliations

  • Published online on: January 1, 1999     https://doi.org/10.3892/or.6.1.71
  • Pages: 71-74
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Abstract

We conducted a prospective cohort study of Nonsteroidal anti-inflammatory drugs (NSAIDs) and breast cancer among 32,505 women in central Ohio, USA. After 5 years of follow-up, a total of 393 cases have been detected. The annual incidence of breast cancer per 100,00 women varied inversely with increasing intake of NSAIDs, declining from 323 among non-users to 183 among heavy users (p<0.01). Breast cancer rates decreased by about 50% with regular ibuprofen intake (p<0.01), and by about 40% with regular aspirin intake (p<0.05). The results suggest that specific NSAIDs may be effective chemopreventive agents against breast cancer.

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January 1999
Volume 6 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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APA
Harris, R., Kasbari, S., & Farrar, W. (1999). Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.. Oncology Reports, 6, 71-74. https://doi.org/10.3892/or.6.1.71
MLA
Harris, R., Kasbari, S., Farrar, W."Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.". Oncology Reports 6.1 (1999): 71-74.
Chicago
Harris, R., Kasbari, S., Farrar, W."Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.". Oncology Reports 6, no. 1 (1999): 71-74. https://doi.org/10.3892/or.6.1.71