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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jan-Feb 1999 Volume 6 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Human chorionic gonadotropin as a target for cancer vaccines.

P L Triozzi, V C Stevens
Pages: 7-24
Published online on: 01 January 1999

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Article

Clinical significance of p53 in non-small-cell lung cancer.

T Komiya, T Hirashima, I Kawase
Pages: 19-47
Published online on: 01 January 1999

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Article

Post-transplantation lymphoproliferative disorder of the T-cell/B-cell type: an unusual manifestation in a renal allograft.

G H Wirnsberger, M Ratschek, H P Dimai, H Holzer, A K Mandal
Pages: 29-61
Published online on: 01 January 1999

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Article

Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.

H Kurokawa, K Nishio, H Fukumoto, A Tomonari, T Suzuki, N Saijo
Pages: 33-40
Published online on: 01 January 1999

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Article

Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity.

A S Multani, C Li, M Ozen, A S Imam, S Wallace, S Pathak
Pages: 39-83
Published online on: 01 January 1999

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Case Report

99m Tc MIBI prone scintimammography in breast Paget's disease: a case report.

S Mezi, F Scopinaro, A Marzullo, E Sallusti, V David, M Ierardi, N S Tiberio, M Modesti
Pages: 45-53
Published online on: 01 January 1999

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Article

Effects of interleukin-2 transduction on the human hepatoma cell lines using retroviral vector.

J H Kim, S J Gong, N C Yoo, H Lee, D H Shin, H D Uhm, S J Jeong, J Y Cho, S Y Rha, Y S Kim, H C Chung, J K Roh, J S Min, B S Kim
Pages: 49-103
Published online on: 01 January 1999

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Article

Scrotal ulcer occurring in patients with acute promyelocytic leukemia during treatment with all-trans retinoic acid.

A Mori, S Tamura, T Katsuno, Y Nishimura, T Itoh, K Saheki, H Takatsuka, H Wada, Y Fujimori, T Okamoto, Y Takemoto, E Kakishita
Pages: 55-63
Published online on: 01 January 1999

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Article

Increased chromosome exchange frequencies in iodo-deoxyuridine-sensitized human SW-1573 cells after gamma-irradiation.

N A Franken, C van Bree, M A Veltmaat, G Ludwików, J B Kipp, G W Barendsen
Pages: 59-122
Published online on: 01 January 1999

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Article

Cytokines in human breast cancer: IL-1alpha and IL-1beta expression.

S H Kurtzman, K H Anderson, Y Wang, L J Miller, M Renna, M Stankus, R R Lindquist, G Barrows, D L Kreutzer
Pages: 65-135
Published online on: 01 January 1999

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Article

Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.

R E Harris, S Kasbari, W B Farrar
Pages: 71-74
Published online on: 01 January 1999

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Article

Synchronous primary lung cancer presenting with small cell carcinoma and non-small cell carcinoma: diagnosis and treatment.

A Hiraki, H Ueoka, T Yoshino, K Chikamori, K Onishi, K Kiura, A Bessho, J Mimoto, H Date, A Ando, N Shimizu, M Harada
Pages: 75-155
Published online on: 01 January 1999

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Article

The reduced expression of e-cadherin, alpha-catenin and gamma-catenin but not beta-catenin in human lung cancer.

H Toyoyama, K Nuruki, H Ogawa, M Yanagi, H Matsumoto, H Nishijima, T Shimotakahara, T Aikou, M Ozawa
Pages: 81-86
Published online on: 01 January 1999

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Article

Fibroblast growth factor-9 (glia-activating factor) stimulates proliferation and production of glial fibrillary acidic protein in human gliomas either in the presence or in the absence of the endogenous growth factor expression.

N Miyagi, S Kato, M Terasaki, T Aoki, Y Sugita, M Yamaguchi, M Shigemori, M Morimatsu
Pages: 87-179
Published online on: 01 January 1999

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Article

Cyclin E overexpression in human gallbladder carcinomas.

N Eguchi, K Fujii, A Tsuchida, S Yamamoto, T Sasaki, G Kajiyama
Pages: 93-99
Published online on: 01 January 1999

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Article

Comparison of p53 and CD44 variant 6 expression between paired primary and recurrent ovarian cancer: an immunohistochemical analysis.

T Kamura, K Sakai, T Kaku, H Kobayashi, M Mitsumoto, M Tsuneyoshi, H Nakano
Pages: 97-198
Published online on: 01 January 1999

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Article

Management of primary gastric lymphomas from a surgeon's viewpoint.

H Ishizuka, T Kubota, N Hayashi, Y Otani, K Kumai, M Kitajima
Pages: 103-109
Published online on: 01 January 1999

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Article

A polyclonal antibody against synthetic peptide conserved in N-Myc protein reacts with water-soluble recombinant N-Myc protein.

H W Yang, H Hemmi, H Ikeda, K Kato, Y Tsuchida
Pages: 107-118
Published online on: 01 January 1999

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Article

High expression of glycosphingolipids involved in procoagulant activity of cancer cells.

M Suzuki, O Ando, T Ohta, H Inufusa, T Adachi, M Yasutomi, M Kurimoto
Pages: 113-118
Published online on: 01 January 1999

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Article

Replication error in human breast cancer: comparison with clinical variables and family history of cancer.

C Huiping, J T Johannsdottir, A Arason, G H Olafsdottir, G Eiriksdottir, V Egilsson, S Ingvarsson
Pages: 117-139
Published online on: 01 January 1999

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Case Report

Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: a case report.

N Umesaki, N Kawamura, A Tsujimura, T Ichimura, T Tanaka, S Ogita
Pages: 123-128
Published online on: 01 January 1999

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Article

Thallium-201-chloride and technetium-99m-MIBI SPECT of primary and metastatic lung carcinoma.

N Kashitani, S Makihara, T Maeda, R Eda, H Takeyama, Y Hiraki
Pages: 127-160
Published online on: 01 January 1999

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Article

Surgical margin and breast recurrence after breast-conserving therapy.

J Horiguchi, Y Iino, H Takei, M Maemura, T Yokoe, H Niibe, M Yamakawa, T Nakajima, T Oyama, Y Morishita
Pages: 135-143
Published online on: 01 January 1999

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Article

A case-control study of the relationship between dietary factors and risk of lung cancer in women of Shenyang, China.

B Zhou, T Wang, G Sun, P Guan, J M Wu
Pages: 139-182
Published online on: 01 January 1999

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Article

Detection of UV-induced K-ras codon 12 mutation by PCR and differential dot-blot hybridization in cells from Down syndrome and Cockayne syndrome.

K Sugita, N Suzuki, K Ohno, Y Suzuki, J I Takanashi, K Kita, H Yamamori, N Nakajima
Pages: 145-152
Published online on: 01 January 1999

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Article

Expression of type I interferon receptor and its relation with other prognostic factors in human neuroblastoma.

C Mejía, S Navarro, O R Colamonici, A Pellín, V Castel, A Llombart-Bosch
Pages: 149-202
Published online on: 01 January 1999

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Article

The measurement of cadmium in biological materials, using graphite furnace atomic absorption spectrometry with Zeeman background correction.

T V Abernathy, K B Lee, R J Parker, E Reed
Pages: 155-164
Published online on: 01 January 1999

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Article

Penclomedine-induced DNA fragmentation and p53 accumulation correlate with reproductive cell death in colorectal carcinoma cells with altered p53 status.

E Rakovitch, W Mellado, E J Hall, S G Sawant, C R Geard, R A Newman, T K Pandita
Pages: 161-166
Published online on: 01 January 1999

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Article

Comparative p53 mutational spectra in aerodigestive tract tumors in Hong Kong Chinese patients.

W C Chan, C S Leung, M L Lung
Pages: 167-239
Published online on: 01 January 1999

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Article

Toxicity and antitumor activity of interferon gamma alone and in combinations with TNFalpha and melphalan in isolated limb perfusion in the BN175 sarcoma tumor model in rats.

E R Manusama, J H De Wilt, T L Ten Hagen, R L Marquet, A M Eggermont
Pages: 173-180
Published online on: 01 January 1999

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Article

Radioimmunotherapy of orthotopically transplanted pancreatic cancer with 131I-labeled chimeric monoclonal antibody Nd2.

A Yamamoto, T Sawada, Y Yamashita, T Nishihara, J J Ho, Y Kim, K H Chung
Pages: 179-263
Published online on: 01 January 1999

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Article

Bone scan and bone biopsy in the detection of skeletal metastases.

I G Ron, A Striecker, H Lerman, A Bar-Am, B Frisch
Pages: 185-193
Published online on: 01 January 1999

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Case Report

Spontaneous pelvic hematoma simulating neoplasm: case report and literature review.

S H Chia, M H Torosian
Pages: 189-280
Published online on: 01 January 1999

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Article

Polymorphisms of the p53 gene in women with ovarian or endometrial carcinoma.

S Peller, R Halperin, D Schneider, Y Kopilova, V Rotter
Pages: 193-200
Published online on: 01 January 1999

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Article

Cytological diagnosis and telomerase activity of cells in effusions of body cavities.

S Toshima, T Arai, Y Yasuda, T Takaya, Y Ito, K Hayakawa, C Shibuya, N Yoshimi, M Shibayama, Y Kashiki
Pages: 199-402
Published online on: 01 January 1999

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Article

Absence of epidermal growth factor receptor expression in squamous cell carcinoma of the uterine cervix is an indicator of limited tumor disease.

S Biesterfeld, S Schuh, L Muys, W Rath, C Mittermayer, W Schröder
Pages: 205-214
Published online on: 01 January 1999

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Article

DNA vaccine against oncogenic hamster cells transformed by HPV16 E6/E7 oncogenes and the activated ras oncogene.

M Smahel, E Sobotkova, V Vonka, E Hamsikova, R Zak, H Kitasato, V Ludvikova
Pages: 211-216
Published online on: 01 January 1999

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Article

The chemosensitizing potential of GF120918 is independent of the magnitude of P-glycoprotein-mediated resistance to conventional chemotherapeutic agents in a small cell lung cancer line.

M S Myer, G Joone, M R Chasen, C E van Rensburg
Pages: 217-225
Published online on: 01 January 1999

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Article

Alternative exon-specific PCR method for the analysis of human CD44 isoform expression.

M S Lockhart, M J Gravisaco, C Mongini, C Waldner, E Alvarez, S E Hajos
Pages: 219-243
Published online on: 01 January 1999

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Article

Effect induced by interleukin-1 on the behaviour of B16F10 melanoma cells.

A G De Galdeano, D Boyano, L Cañavate
Pages: 225-233
Published online on: 01 January 1999

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Article

Analysis of the cyclin-dependent kinase inhibitor p27Kip1 in muscle invasive bladder cancer.

J Serth, M Kuczyk, S Machtens, C Bokemeyer, R Herrmann, J Hartmann, R Knüchel, U Jonas
Pages: 229-262
Published online on: 01 January 1999

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Article

Relationships betxween Fas expression, activation molecule CD25, and functional activity of tumor-associated lymphomonocytes from neoplastic effusions.

G Mantovani, A Macciò, E Massa, P Lai, G Manca, C Mudu, R Versace, G Pusceddu
Pages: 235-244
Published online on: 01 January 1999

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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